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Catalog No: ARP32466_T100
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ARP32466_T100
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PCAF Antibody - N-terminal region (ARP32466_T100)

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Datasheets/ManualsPrintable datasheet for anti-KAT2B (ARP32466_T100) antibody
Product Info
Tested Species ReactivityHuman
Predicted Species ReactivityHuman, Mouse, Rat, Cow, Dog, Guinea Pig, Horse, Rabbit, Zebrafish
Product FormatLiquid. Purified antibody supplied in 1x PBS buffer with 0.09% (w/v) sodium azide and 2% sucrose.
ClonalityPolyclonal
HostRabbit
ApplicationWB
Reconstitution and StorageFor short term use, store at 2-8C up to 1 week. For long term storage, store at -20C in small aliquots to prevent freeze-thaw cycles.
ImmunogenThe immunogen is a synthetic peptide directed towards the N terminal region of human PCAF
PurificationProtein A purified
Predicted Homology Based on Immunogen SequenceCow: 100%; Dog: 100%; Guinea Pig: 100%; Horse: 100%; Human: 100%; Mouse: 100%; Rabbit: 100%; Rat: 100%; Zebrafish: 90%
Peptide SequenceSynthetic peptide located within the following region: LFKLLRKSILQRGKPVVEGSLEKKPPFEKPSIEQGVNNFVQYKFSHLPAK
Concentration1.0 mg/ml
Blocking PeptideFor anti-KAT2B (ARP32466_T100) antibody is Catalog # AAP32466 (Previous Catalog # AAPP03464)
ReferenceChu,B.Y., Biochem. J. 392 (PT 3), 589-599 (2005)
Gene SymbolKAT2B
Gene Full NameK(lysine) acetyltransferase 2B
Alias SymbolsCAF, PCAF, P/CAF
NCBI Gene Id8850
Protein NameHistone acetyltransferase KAT2B
Description of TargetCBP and p300 are large nuclear proteins that bind to many sequence-specific factors involved in cell growth and/or differentiation, including c-jun and the adenoviral oncoprotein E1A. PCAF associates with p300/CBP. It has in vitro and in vivo binding activity with CBP and p300, and competes with E1A for binding sites in p300/CBP. It has histone acetyl transferase activity with core histones and nucleosome core particles, indicating that this protein plays a direct role in transcriptional regulation.CBP and p300 are large nuclear proteins that bind to many sequence-specific factors involved in cell growth and/or differentiation, including c-jun and the adenoviral oncoprotein E1A. The protein encoded by this gene associates with p300/CBP. It has in vitro and in vivo binding activity with CBP and p300, and competes with E1A for binding sites in p300/CBP. It has histone acetyl transferase activity with core histones and nucleosome core particles, indicating that this protein plays a direct role in transcriptional regulation.
Uniprot IDQ92831
Protein Accession #NP_003875
Nucleotide Accession #NM_003884
Protein Size (# AA)832
Molecular Weight93kDa
Protein InteractionsMDM2; HNRNPD; ACLY; KLF2; E2F1; VHL; IRF1; TAL1; TAF12; TAF10; TAF9; TADA2A; RB1; HIST1H1B; TAF5L; TAF6L; TADA3; SUPT3H; TWIST1; PDK1; AKT1; UBC; SIAH2; UBE2D3; UBE2D1; TP73; TP53; SRC; PGR; YEATS2; MBIP; WDR5; PTEN; DR1; HIF1A; HIST2H3C; CHEK2; HIST1H4A;
  1. What is the species homology for "PCAF Antibody - N-terminal region (ARP32466_T100)"?

    The tested species reactivity for this item is "Human". This antibody is predicted to have homology to "Human, Mouse, Rat, Cow, Dog, Guinea Pig, Horse, Rabbit, Zebrafish".

  2. How long will it take to receive "PCAF Antibody - N-terminal region (ARP32466_T100)"?

    This item is available "Domestic: within 1-2 days delivery | International: 1-2 days".

  3. What buffer format is "PCAF Antibody - N-terminal region (ARP32466_T100)" provided in?

    This item is provided in "Liquid. Purified antibody supplied in 1x PBS buffer with 0.09% (w/v) sodium azide and 2% sucrose.".
    Additional format options may be available. For more information please contact info@avivasysbio.com.

  4. What are other names for "PCAF Antibody - N-terminal region (ARP32466_T100)"?

    This target may also be called "CAF, PCAF, P/CAF" in publications.

  5. What is the shipping cost for "PCAF Antibody - N-terminal region (ARP32466_T100)"?

    The shipping cost for this item is $40 within the US. Please contact us for specific shipping prices for international orders.

  6. What is the guarantee for "PCAF Antibody - N-terminal region (ARP32466_T100)"?

    All Aviva products have been through rigorous validations and carry 100% satisfaction guarantee.

  7. Can I get bulk pricing for "PCAF Antibody - N-terminal region (ARP32466_T100)"?

    You can get bulk pricing for this item by going here.

  8. What is the molecular weight of the protein?

    The molecular weight reported by Uniprot for this item is "93kDa".
    Please note observed molecular weights in western blot applications may differ depending on a variety of protein characteristics.

  9. What protocols are available for "PCAF Antibody - N-terminal region (ARP32466_T100)"?

    We may have detailed protocol data avaialble for this item. To learn more, please view the "Protocols & Data" tab on the product page.

  10. What are positive controls for "KAT2B"?

    We have listed RNA Seq and gene expression data in the "Target Info" tab. You may be able to find adequate positive controls there.

  11. What are negative controls for "KAT2B"?

    We have listed RNA Seq and gene expression data in the "Target Info" tab. You may be able to find adequate positive controls there.

  12. What other proteins interact with "KAT2B"?

    This protein has been reported to interact with "Protein Interactions". Please view the "Related Categories" tab on the product page for more information.

  13. What biological processes are associated with "KAT2B"?

    This protein has been associated with "Biological Processes". Please view the "Related Categories" tab on the product page for more information.

  14. What cellular components are associated with "KAT2B"?

    This protein has been associated with "Cellular Components". Please view the "Related Categories" tab on the product page for more information.

  15. What protein functions are associated with "KAT2B"?

    This protein has been associated with "Protein Functions". Please view the "Related Categories" tab on the product page for more information.

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