LITAF Antibody - N-terminal region (ARP74033_P050)

Catalog No: ARP74033_P050

Host: Rabbit
Target Name: LITAF
Sample Type: 786-0 Whole Cell lysates
Antibody Dilution: 1.0ug/ml

Product Info

• Tested Species Reactivity: Human
• Predicted Species Reactivity: Human
• Product Format: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09% (w/v) sodium azide and 2% sucrose.
• Clonality: Polyclonal
• Host: Rabbit
• Application: WB
• Reconstitution and Storage: For short term use, store at 2-8C up to 1 week. For long term storage, store at -20C in small aliquots to prevent freeze-thaw cycles.
• Immunogen: The immunogen is a synthetic peptide directed towards the N-terminal region of Human LITAF
• Purification: Affinity Purified
• Peptide Sequence: Synthetic peptide located within the following region: PSYEETVAVNSYYPTPPAPMPGPTTGLVTGPDGKGMNPPSYYTQPAPIPN
• Concentration: 0.5 mg/ml
• Blocking Peptide: For anti-LITAF (ARP74033_P050) antibody is Catalog # AAP74033

Target Info

• Gene Symbol: LITAF
• Alias Symbols: PIG7, SIMPLE, TP53I7
• NCBI Gene Id: 9516
• Description of Target: Lipopolysaccharide is a potent stimulator of monocytes and macrophages, causing secretion of tumor necrosis factor-alpha (TNF-alpha) and other inflammatory mediators. This gene encodes lipopolysaccharide-induced TNF-alpha factor, which is a DNA-binding protein and can mediate the TNF-alpha expression by direct binding to the promoter region of the TNF-alpha gene. The transcription of this gene is induced by tumor suppresor p53 and has been implicated in the p53-induced apoptotic pathway. Mutations in this gene cause Charcot-Marie-Tooth disease type 1C (CMT1C) and may be involved in the carcinogenesis of extramammary Paget's disease (EMPD). Multiple alternatively spliced transcript variants have been found for this gene.
• Uniprot ID: Q99732-2
• Protein Size (# AA): 228
• Molecular Weight: 25kDa
• Protein Interactions: REEP6; UBQLN1; STAM2; CALCOCO2; BAG3; HGS; UBC; STAT6; ATXN1; ITCH; TSG101; NEDD4; ELAVL1; RADIL; SMAD2; COMT;