KLC3 Antibody - middle region (ARP53346_P050)

Catalog No: ARP53346_P050

WB Suggested Anti-KLC3 Antibody Titration: 0.2-1 ug/ml
Positive Control: Jurkat cell lysate

Product Info

• Tested Species Reactivity: Human
• Predicted Species Reactivity: Human, Mouse, Rat, Cow, Dog, Guinea Pig, Horse, Rabbit
• Product Format: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09% (w/v) sodium azide and 2% sucrose.
• Clonality: Polyclonal
• Host: Rabbit
• Application: WB
• Reconstitution and Storage: For short term use, store at 2-8C up to 1 week. For long term storage, store at -20C in small aliquots to prevent freeze-thaw cycles.
• Immunogen: The immunogen is a synthetic peptide directed towards the middle region of human KLC3
• Purification: Affinity Purified
• Predicted Homology Based on Immunogen Sequence: Cow: 93%; Dog: 86%; Guinea Pig: 86%; Horse: 92%; Human: 100%; Mouse: 100%; Rabbit: 77%; Rat: 100%
• Peptide Sequence: Synthetic peptide located within the following region: LLCQNQGKFEDVERHYARALSIYEALGGPHDPNVAKTKNNLASAYLKQNK
• Concentration: 0.5 mg/ml
• Blocking Peptide: For anti-KLC3 (ARP53346_P050) antibody is Catalog # AAP53346 (Previous Catalog # AAPP30929)
• Reference: Zhang,Y., (2004) Dev. Biol. 275 (1), 23-33

Target Info

• Gene Symbol: KLC3
• Gene Full Name: Kinesin light chain 3
• Alias Symbols: KLC2, KLCt, KLC2L, KNS2B
• NCBI Gene Id: 147700
• Protein Name: Kinesin light chain 3
• Description of Target: KLC3 is a member of the kinesin light chain gene family. Kinesins are molecular motors involved in the transport of cargo along microtubules, and are composed of two kinesin heavy chain (KHC) and two kinesin light chain (KLC) molecules. KLCs are thought to typically be involved in binding cargo and regulating kinesin activity. In the rat, a protein similar to this gene product is expressed in post-meiotic spermatids, where it associates with structural components of sperm tails and mitochondria.This gene encodes a member of the kinesin light chain gene family. Kinesins are molecular motors involved in the transport of cargo along microtubules, and are composed of two kinesin heavy chain (KHC) and two kinesin light chain (KLC) molecules. KLCs are thought to typically be involved in binding cargo and regulating kinesin activity. In the rat, a protein similar to this gene product is expressed in post-meiotic spermatids, where it associates with structural components of sperm tails and mitochondria.
• Uniprot ID: Q6P597
• Protein Accession #: NP_803136
• Nucleotide Accession #: NM_177417
• Protein Size (# AA): 504
• Molecular Weight: 55kDa
• Protein Interactions: CENPP; CCDC36; CEP57L1; SPERT; KLC3; ZNF417; CCDC64B; ZNF572; BBS5; SNAP47; DTX2; USHBP1; IMP3; NECAB2; MBIP; WAC; ABI3; KDM1A; NDC80; PDE4DIP; STX11; TSNAX; TCF4; VPS52; QARS; KRT15; KRT13; GEM; CCNH; YWHAE; DYNC1I1; CUL2; CROCC; KIF5A; KIF5B; YWHAG; YWH