GDI1 Antibody - C-terminal region (AVARP13086_T100)

Catalog No: AVARP13086_T100

WB Suggested Anti-GDI1 Antibody Titration: 1.25ug/ml
ELISA Titer: 1:312500
Positive Control: HepG2 cell lysate

Human, Mouse

Host: Mouse
Target Name: GDI1
Sample Tissue: Mouse Heart
Antibody Dilution: 1ug/ml

Product Info

• Tested Species Reactivity: Human, Mouse
• Predicted Species Reactivity: Human, Mouse, Guinea Pig, Horse, Rabbit, Sheep, Zebrafish
• Product Format: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09% (w/v) sodium azide and 2% sucrose.
• Clonality: Polyclonal
• Host: Rabbit
• Application: WB
• Reconstitution and Storage: For short term use, store at 2-8C up to 1 week. For long term storage, store at -20C in small aliquots to prevent freeze-thaw cycles.
• Immunogen: The immunogen is a synthetic peptide directed towards the C terminal region of human GDI1
• Purification: Protein A purified
• Predicted Homology Based on Immunogen Sequence: Guinea Pig: 92%; Horse: 92%; Human: 100%; Mouse: 92%; Rabbit: 92%; Sheep: 92%; Zebrafish: 92%
• Peptide Sequence: Synthetic peptide located within the following region: VFCSCSYDATTHFETTCNDIKDIYKRMAGTAFDFENMKRKQNDVFGEAEQ
• Concentration: 1.0 mg/ml
• Blocking Peptide: For anti-GDI1 (AVARP13086_T100) antibody is Catalog # AAP30750 (Previous Catalog # AAPP01411)
• Reference: Papaharalambus,C., et al., (2005) J. Biol. Chem. 280 (19), 18790-18796

Target Info

• Gene Symbol: GDI1
• Gene Full Name: GDP dissociation inhibitor 1
• Alias Symbols: 1A, GDIL, MRX41, MRX48, OPHN2, XAP-4, RABGD1A, RABGDIA
• NCBI Gene Id: 2664
• Protein Name: Rab GDP dissociation inhibitor alpha
• Description of Target: GDP dissociation inhibitors are proteins that regulate the GDP-GTP exchange reaction of members of the rab family, small GTP-binding proteins of the ras superfamily, that are involved in vesicular trafficking of molecules between cellular organelles. GDIs slow the rate of dissociation of GDP from rab proteins and release GDP from membrane-bound rabs. GDI1 is expressed primarily in neural and sensory tissues. Mutations in GDI1 have been linked to X-linked nonspecific mental retardation.
• Uniprot ID: P31150
• Protein Accession #: NP_001484
• Nucleotide Accession #: NM_001493
• Protein Size (# AA): 447
• Molecular Weight: 51kDa
• Protein Interactions: LNX1; UBC; RCC2; DCUN1D1; ACOT7; GGH; HIST1H2BO; SGTA; NEDD8; HEXA; GNAI2; ASL; ALDH9A1; SCRN1; GINS3; IQCB1; GNL1; RAB11B; RAB1A; PCMT1; UBQLN4; CUL5; CDK2; SIRT7; MINOS1; TK1; RAB24; RAB1B; RABAC1; RAB27A; RAC2; RHOH; RAB9A; RAB6A; EPB41; CDC42; PSEN1;