Catalog No: ARP43653_P050
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ARP43653_P050
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Datasheets/ManualsPrintable datasheet for anti-ABCC1 (ARP43653_P050) antibody
Product Info
Tested Species ReactivityHuman
Predicted Species ReactivityHuman, Rat, Cow, Dog, Guinea Pig, Horse, Pig, Rabbit
Product FormatLiquid. Purified antibody supplied in 1x PBS buffer with 0.09% (w/v) sodium azide and 2% sucrose.
ClonalityPolyclonal
HostRabbit
ApplicationWB
Reconstitution and StorageFor short term use, store at 2-8C up to 1 week. For long term storage, store at -20C in small aliquots to prevent freeze-thaw cycles.
ImmunogenThe immunogen is a synthetic peptide directed towards the middle region of human ABCC1
PurificationAffinity Purified
Predicted Homology Based on Immunogen SequenceCow: 100%; Dog: 100%; Guinea Pig: 77%; Horse: 92%; Human: 100%; Pig: 100%; Rabbit: 93%; Rat: 85%
Peptide SequenceSynthetic peptide located within the following region: LFISFLSIFLFMCNHVSALASNYWLSLWTDDPIVNGTQEHTKVRLSVYGA
Concentration0.5 mg/ml
Blocking PeptideFor anti-ABCC1 (ARP43653_P050) antibody is Catalog # AAP43653 (Previous Catalog # AAPP11642)
ReferenceNabekura,T., (2008) Biochem. Biophys. Res. Commun. 369 (2), 363-368
Gene SymbolABCC1
Gene Full NameATP-binding cassette, sub-family C (CFTR/MRP), member 1
Alias SymbolsMRP, ABCC, GS-X, MRP1, ABC29, DFNA77
NCBI Gene Id4363
Protein NameMultidrug resistance-associated protein 1
Description of TargetABCC1 is a member of the superfamily of ATP-binding cassette (ABC) transporters. ABC proteins transport various molecules across extra-and intra-cellular membranes. ABC genes are divided into seven distinct subfamilies (ABC1, MDR/TAP, MRP, ALD, OABP, GCN20, White). This full transporter is a member of the MRP subfamily which is involved in multi-drug resistance. This protein functions as a multispecific organic anion transporter, with oxidized glutatione, cysteinyl leukotrienes, and activated aflatoxin B1 as substrates. This protein also transports glucuronides and sulfate conjugates of steroid hormones and bile salts. Alternative splicing by exon deletion results in several splice variants but maintains the original open reading frame in all forms. The protein encoded by this gene is a member of the superfamily of ATP-binding cassette (ABC) transporters. ABC proteins transport various molecules across extra-and intra-cellular membranes. ABC genes are divided into seven distinct subfamilies (ABC1, MDR/TAP, MRP, ALD, OABP, GCN20, White). This full transporter is a member of the MRP subfamily which is involved in multi-drug resistance. This protein functions as a multispecific organic anion transporter, with oxidized glutatione, cysteinyl leukotrienes, and activated aflatoxin B1 as substrates. This protein also transports glucuronides and sulfate conjugates of steroid hormones and bile salts. Alternative splicing by exon deletion results in several splice variants but maintains the original open reading frame in all forms.
Uniprot IDP33527
Protein Accession #NP_004987
Nucleotide Accession #NM_004996
Protein Size (# AA)1531
Molecular Weight171kDa
Protein InteractionsUBC; ABCC1; CAV1; TRAF3; NPM1; AZGP1; STT3B; RAVER1; MCU; MRPL17; TMCO1; ATP6V1H; TMX2; TMOD2; NDUFAF3; FKBP8; PUF60; PGRMC2; FLOT1; PDCD6IP; ATP6V1F; EIF3C; PDHX; VDAC3; SURF1; STX4; SAFB; RPS7; NDUFB9; DBT; TMEM173; UNC93B1;
  1. What is the species homology for "ABCC1 Antibody - middle region (ARP43653_P050)"?

    The tested species reactivity for this item is "Human". This antibody is predicted to have homology to "Human, Rat, Cow, Dog, Guinea Pig, Horse, Pig, Rabbit".

  2. How long will it take to receive "ABCC1 Antibody - middle region (ARP43653_P050)"?

    This item is available "Domestic: within 1-2 days delivery | International: 1-2 days".

  3. What buffer format is "ABCC1 Antibody - middle region (ARP43653_P050)" provided in?

    This item is provided in "Liquid. Purified antibody supplied in 1x PBS buffer with 0.09% (w/v) sodium azide and 2% sucrose.".
    Additional format options may be available. For more information please contact info@avivasysbio.com.

  4. What are other names for "ABCC1 Antibody - middle region (ARP43653_P050)"?

    This target may also be called "MRP, ABCC, GS-X, MRP1, ABC29, DFNA77" in publications.

  5. What is the shipping cost for "ABCC1 Antibody - middle region (ARP43653_P050)"?

    The shipping cost for this item is $40 within the US. Please contact us for specific shipping prices for international orders.

  6. What is the guarantee for "ABCC1 Antibody - middle region (ARP43653_P050)"?

    All Aviva products have been through rigorous validations and carry 100% satisfaction guarantee.

  7. Can I get bulk pricing for "ABCC1 Antibody - middle region (ARP43653_P050)"?

    You can get bulk pricing for this item by going here.

  8. What is the molecular weight of the protein?

    The molecular weight reported by Uniprot for this item is "171kDa".
    Please note observed molecular weights in western blot applications may differ depending on a variety of protein characteristics.

  9. What protocols are available for "ABCC1 Antibody - middle region (ARP43653_P050)"?

    We may have detailed protocol data avaialble for this item. To learn more, please view the "Protocols & Data" tab on the product page.

  10. What are positive controls for "ABCC1"?

    We have listed RNA Seq and gene expression data in the "Target Info" tab. You may be able to find adequate positive controls there.

  11. What are negative controls for "ABCC1"?

    We have listed RNA Seq and gene expression data in the "Target Info" tab. You may be able to find adequate positive controls there.

  12. What other proteins interact with "ABCC1"?

    This protein has been reported to interact with "Protein Interactions". Please view the "Related Categories" tab on the product page for more information.

  13. What biological processes are associated with "ABCC1"?

    This protein has been associated with "Biological Processes". Please view the "Related Categories" tab on the product page for more information.

  14. What cellular components are associated with "ABCC1"?

    This protein has been associated with "Cellular Components". Please view the "Related Categories" tab on the product page for more information.

  15. What protein functions are associated with "ABCC1"?

    This protein has been associated with "Protein Functions". Please view the "Related Categories" tab on the product page for more information.

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