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Datasheets/Manuals | Printable datasheet for anti-ABCB4 (ARP41741_P050) antibody |
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Tested Species Reactivity | Human | ||||||
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Predicted Species Reactivity | Human, Mouse, Rat, Cow, Dog, Guinea Pig, Horse, Pig, Rabbit, Sheep | ||||||
Product Format | Liquid. Purified antibody supplied in 1x PBS buffer with 0.09% (w/v) sodium azide and 2% sucrose. | ||||||
Clonality | Polyclonal | ||||||
Host | Rabbit | ||||||
Application | WB | ||||||
Reconstitution and Storage | For short term use, store at 2-8C up to 1 week. For long term storage, store at -20C in small aliquots to prevent freeze-thaw cycles. | ||||||
Immunogen | The immunogen is a synthetic peptide directed towards the N terminal region of human ABCB4 | ||||||
Purification | Affinity Purified | ||||||
Predicted Homology Based on Immunogen Sequence | Cow: 86%; Dog: 77%; Guinea Pig: 77%; Horse: 77%; Human: 100%; Mouse: 100%; Pig: 93%; Rabbit: 100%; Rat: 100%; Sheep: 77% | ||||||
Peptide Sequence | Synthetic peptide located within the following region: AGAVAEEALGAIRTVIAFGGQNKELERYQKHLENAKEIGIKKAISANISM | ||||||
Concentration | 0.5 mg/ml | ||||||
Blocking Peptide | For anti-ABCB4 (ARP41741_P050) antibody is Catalog # AAP41741 (Previous Catalog # AAPP24384) | ||||||
Enhanced Validation |
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Reference | Floreani,A., (2008) Dig Liver Dis 40 (5), 366-370 |
Gene Symbol | ABCB4 |
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Gene Full Name | ATP-binding cassette, sub-family B (MDR/TAP), member 4 |
Alias Symbols | GBD1, ICP3, MDR2, MDR3, PGY3, ABC21, MDR2/3, PFIC-3 |
NCBI Gene Id | 5244 |
Protein Name | Phosphatidylcholine translocator ABCB4 |
Description of Target | ABCB4, a membrane-associated protein, is a member of the superfamily of ATP-binding cassette (ABC) transporters. ABC proteins transport various molecules across extra- and intra-cellular membranes. This protein is a member of the MDR/TAP subfamily. Members of the MDR/TAP subfamily are involved in multidrug resistance as well as antigen presentation. ABCB4 is a full transporter and member of the p-glycoprotein family of membrane proteins with phosphatidylcholine as its substrate. The function of this protein has not yet been determined; however, it may involve transport of phospholipids from liver hepatocytes into bile.The membrane-associated protein encoded by this gene is a member of the superfamily of ATP-binding cassette (ABC) transporters. ABC proteins transport various molecules across extra- and intra-cellular membranes. ABC genes are divided into seven distinct subfamilies (ABC1, MDR/TAP, MRP, ALD, OABP, GCN20, White). This protein is a member of the MDR/TAP subfamily. Members of the MDR/TAP subfamily are involved in multidrug resistance as well as antigen presentation. This gene encodes a full transporter and member of the p-glycoprotein family of membrane proteins with phosphatidylcholine as its substrate. The function of this protein has not yet been determined; however, it may involve transport of phospholipids from liver hepatocytes into bile. Alternative splicing of this gene results in several products of undetermined function. |
Uniprot ID | A4D1D4 |
Protein Accession # | NP_000434 |
Nucleotide Accession # | NM_000443 |
Protein Size (# AA) | 1279 |
Molecular Weight | 142 kDa |
Protein Interactions | PIGY; TESK1; HAX1; |
- Protocol:
- Reconstitution & Storage Instructions
- Western Blotting/Immunoblotting (WB/IB) Protocol
- Immunohistochemistry (IHC) Protocol
- Immunocytochemistry (ICC) Protocol
- Enzyme-Linked ImmunoSorbent Assay (ELISA) Protocol
- Blocking Peptide Competition Protocol (BPCP)
- Immunoprecipitation (IP) Protocol
- Antibody Array (AA) Protocol
- Tips Information:
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See our General FAQ page.
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What is the species homology for "ABCB4 Antibody - N-terminal region (ARP41741_P050)"?
The tested species reactivity for this item is "Human". This antibody is predicted to have homology to "Human, Mouse, Rat, Cow, Dog, Guinea Pig, Horse, Pig, Rabbit, Sheep".
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How long will it take to receive "ABCB4 Antibody - N-terminal region (ARP41741_P050)"?
This item is available "Domestic: within 1-2 days delivery | International: 1-2 days".
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What buffer format is "ABCB4 Antibody - N-terminal region (ARP41741_P050)" provided in?
This item is provided in "Liquid. Purified antibody supplied in 1x PBS buffer with 0.09% (w/v) sodium azide and 2% sucrose.".
Additional format options may be available. For more information please contact info@avivasysbio.com. -
What are other names for "ABCB4 Antibody - N-terminal region (ARP41741_P050)"?
This target may also be called "GBD1, ICP3, MDR2, MDR3, PGY3, ABC21, MDR2/3, PFIC-3" in publications.
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What is the shipping cost for "ABCB4 Antibody - N-terminal region (ARP41741_P050)"?
The shipping cost for this item is $40 within the US. Please contact us for specific shipping prices for international orders.
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What is the guarantee for "ABCB4 Antibody - N-terminal region (ARP41741_P050)"?
All Aviva products have been through rigorous validations and carry 100% satisfaction guarantee.
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Can I get bulk pricing for "ABCB4 Antibody - N-terminal region (ARP41741_P050)"?
You can get bulk pricing for this item by going here.
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What is the molecular weight of the protein?
The molecular weight reported by Uniprot for this item is "142 kDa".
Please note observed molecular weights in western blot applications may differ depending on a variety of protein characteristics. -
What protocols are available for "ABCB4 Antibody - N-terminal region (ARP41741_P050)"?
We may have detailed protocol data avaialble for this item. To learn more, please view the "Protocols & Data" tab on the product page.
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What are positive controls for "ABCB4"?
We have listed RNA Seq and gene expression data in the "Target Info" tab. You may be able to find adequate positive controls there.
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What are negative controls for "ABCB4"?
We have listed RNA Seq and gene expression data in the "Target Info" tab. You may be able to find adequate positive controls there.
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What other proteins interact with "ABCB4"?
This protein has been reported to interact with "Protein Interactions". Please view the "Related Categories" tab on the product page for more information.
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What biological processes are associated with "ABCB4"?
This protein has been associated with "Biological Processes". Please view the "Related Categories" tab on the product page for more information.
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What cellular components are associated with "ABCB4"?
This protein has been associated with "Cellular Components". Please view the "Related Categories" tab on the product page for more information.
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What protein functions are associated with "ABCB4"?
This protein has been associated with "Protein Functions". Please view the "Related Categories" tab on the product page for more information.