WFDC1 Antibody - N-terminal region (ARP57525_P050)

Catalog No: ARP57525_P050

WB Suggested Anti-WFDC1 Antibody Titration: 0.2-1 ug/ml
ELISA Titer: 1:312500
Positive Control: Human Placenta

Product Info

• Tested Species Reactivity: Human
• Predicted Species Reactivity: Human, Dog
• Product Format: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09% (w/v) sodium azide and 2% sucrose.
• Clonality: Polyclonal
• Host: Rabbit
• Application: WB
• Reconstitution and Storage: For short term use, store at 2-8C up to 1 week. For long term storage, store at -20C in small aliquots to prevent freeze-thaw cycles.
• Immunogen: The immunogen is a synthetic peptide directed towards the N terminal region of human WFDC1
• Purification: Affinity Purified
• Predicted Homology Based on Immunogen Sequence: Dog: 91%; Human: 100%
• Peptide Sequence: Synthetic peptide located within the following region: WKRALPARLAEKSRAEEAGAPGGPRQPRADRCPPPPRTLPPGACQAARCQ
• Concentration: 0.5 mg/ml
• Blocking Peptide: For anti-WFDC1 (ARP57525_P050) antibody is Catalog # AAP57525 (Previous Catalog # AAPP41638)

Target Info

• Gene Symbol: WFDC1
• Gene Full Name: WAP four-disulfide core domain 1
• Alias Symbols: PS20
• NCBI Gene Id: 58189
• Protein Name: WAP four-disulfide core domain protein 1
• Description of Target: This gene encodes a member of the WAP-type four disulfide core domain family. The WAP-type four-disulfide core domain, or WAP signature motif, contains eight cysteines forming four disulfide bonds at the core of the protein, and functions as a protease inhibitor in many family members. The encoded protein shares 81% amino acid identity with the rat ps20 protein, which was originally identified as a secreted growth inhibitor. This gene is mapped to chromosome 16q24, an area of frequent loss of heterozygosity in cancers, including prostate, breast and hepatocellular cancers and Wilms' tumor. Owing to its location and a possible growth inhibitory property of its gene product, this gene is suggested to be a tumor suppressor gene.
• Uniprot ID: Q9HC57
• Protein Accession #: NP_067020
• Nucleotide Accession #: NM_021197
• Protein Size (# AA): 220
• Molecular Weight: 21kDa
• Protein Interactions: EZR; ZNF677; RAB40B; FOSL1; XRCC2;