Catalog No: ARP50888_P050
Price: $0.00
SKU
ARP50888_P050
Availability: Domestic: within 1-2 days delivery | International: 1-2 days
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Datasheets/ManualsPrintable datasheet for ARP50888_P050
Product Info
Tested Species ReactivityHuman
Predicted Species ReactivityHuman
Product FormatLiquid. Purified antibody supplied in 1x PBS buffer with 0.09% (w/v) sodium azide and 2% sucrose.
ClonalityPolyclonal
HostRabbit
ApplicationWB
Reconstitution and StorageFor short term use, store at 2-8C up to 1 week. For long term storage, store at -20C in small aliquots to prevent freeze-thaw cycles.
ImmunogenThe immunogen is a synthetic peptide directed towards the middle region of human RBBP8
PurificationAffinity Purified
Predicted Homology Based on Immunogen SequenceHuman: 100%
Peptide SequenceSynthetic peptide located within the following region: CQQKKEKRNWLPAQDTDSATFHPTHQRIFGKLVFLPLRLVWKEVILRKIL
Concentration0.5 mg/ml
Blocking PeptideCatalog # AAP50888 (Previous Catalog # AAPs30412)
Sample Type Confirmation

RBBP8 is supported by BioGPS gene expression data to be expressed in ACHN

Gene SymbolRBBP8
Gene Full NameRetinoblastoma binding protein 8
Alias SymbolsRIM, COM1, CTIP, JWDS, SAE2, SCKL2
NCBI Gene Id5932
Protein NameDNA endonuclease RBBP8 Ensembl ENSP00000382630
Description of TargetRBBP8 is a ubiquitously expressed nuclear protein. It is found among several proteins that bind directly to retinoblastoma protein, which regulates cell proliferation. This protein complexes with transcriptional co-repressor CTBP. It is also associated with BRCA1 and is thought to modulate the functions of BRCA1 in transcriptional regulation, DNA repair, and/or cell cycle checkpoint control. It is suggested that this gene may itself be a tumor suppressor acting in the same pathway as BRCA1. Three transcript variants encoding two different isoforms have been found for this gene. More transcript variants exist, but their full-length natures have not been determined.
Uniprot IDA6NKN2
Protein Accession #NP_976037
Nucleotide Accession #NM_203292
Protein Size (# AA)867
Molecular Weight98kDa
Protein InteractionsLMO4; PIN1; LMO1; MDM2; BRCA1; RBL1; TMEM54; PRRG4; RGS17; IKBKG; IGFBP7; EEF1A1; CTBP2; CLU; MAP2K4; RAF1; RBL2; PCNA; ZNF350; NBN; UIMC1; PALB2; BARD1; SPEN; RAD50; CTBP1; RB1; UBC; FXR2; RBBP8; IKZF1; LIMS1; SIAH2; SIAH1; LMO2; WDYHV1; ATM; TGIF2; IKZF
  1. What is the species homology for "RBBP8 Antibody - middle region (ARP50888_P050)"?

    The tested species reactivity for this item is "Human". This antibody is predicted to have homology to "Human".

  2. How long will it take to receive "RBBP8 Antibody - middle region (ARP50888_P050)"?

    This item is available "Domestic: within 1-2 days delivery | International: 1-2 days".

  3. What buffer format is "RBBP8 Antibody - middle region (ARP50888_P050)" provided in?

    This item is provided in "Liquid. Purified antibody supplied in 1x PBS buffer with 0.09% (w/v) sodium azide and 2% sucrose.".
    Additional format options may be available. For more information please contact info@avivasysbio.com.

  4. What are other names for "RBBP8 Antibody - middle region (ARP50888_P050)"?

    This target may also be called "RIM, COM1, CTIP, JWDS, SAE2, SCKL2" in publications.

  5. What is the shipping cost for "RBBP8 Antibody - middle region (ARP50888_P050)"?

    The shipping cost for this item is $40 within the US. Please contact us for specific shipping prices for international orders.

  6. What is the guarantee for "RBBP8 Antibody - middle region (ARP50888_P050)"?

    All Aviva products have been through rigorous validations and carry 100% satisfaction guarantee.

  7. Can I get bulk pricing for "RBBP8 Antibody - middle region (ARP50888_P050)"?

    You can get bulk pricing for this item by going here.

  8. What is the molecular weight of the protein?

    The molecular weight reported by Uniprot for this item is "98kDa".
    Please note observed molecular weights in western blot applications may differ depending on a variety of protein characteristics.

  9. What protocols are available for "RBBP8 Antibody - middle region (ARP50888_P050)"?

    We may have detailed protocol data avaialble for this item. To learn more, please view the "Protocols & Data" tab on the product page.

  10. What are positive controls for "RBBP8"?

    We have listed RNA Seq and gene expression data in the "Target Info" tab. You may be able to find adequate positive controls there.

  11. What are negative controls for "RBBP8"?

    We have listed RNA Seq and gene expression data in the "Target Info" tab. You may be able to find adequate positive controls there.

  12. What other proteins interact with "RBBP8"?

    This protein has been reported to interact with "Protein Interactions". Please view the "Related Categories" tab on the product page for more information.

  13. What biological processes are associated with "RBBP8"?

    This protein has been associated with "Biological Processes". Please view the "Related Categories" tab on the product page for more information.

  14. What cellular components are associated with "RBBP8"?

    This protein has been associated with "Cellular Components". Please view the "Related Categories" tab on the product page for more information.

  15. What protein functions are associated with "RBBP8"?

    This protein has been associated with "Protein Functions". Please view the "Related Categories" tab on the product page for more information.

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