- Description of Target:
- This protein is a member of the non-histone chromosomal high mobility group family. The proteins of this family are chromatin-associated and ubiquitously distributed in the nucleus of higher eukaryotic cells. In vitro studies have demonstrated that this protein is able to efficiently bend DNA and form DNA circles. These studies suggest a role in facilitating cooperative interactions between cis-acting proteins by promoting DNA flexibility. This protein was also reported to be involved in the final ligation step in the DNA end-joining processes of DNA double-strand breaks repair and V(D)J recombination.This gene encodes a member of the non-histone chromosomal high mobility group protein family. The proteins of this family are chromatin-associated and ubiquitously distributed in the nucleus of higher eukaryotic cells. In vitro studies have demonstrated that this protein is able to efficiently bend DNA and form DNA circles. These studies suggest a role in facilitating cooperative interactions between cis-acting proteins by promoting DNA flexibility. This protein was also reported to be involved in the final ligation step in DNA end-joining processes of DNA double-strand breaks repair and V(D)J recombination. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Entrez Gene record to access additional publications.
- Gene Symbol:
- HMGB2
- Official Gene Full Name:
- High mobility group box 2
- Alias Symbols:
- HMG2
- Tissue Tool:
- Find tissues and cell lines supported to express HMGB2.
- Protein Accession# :
- NP_002120
- Nucleotide Accession#:
- NM_002129
- Swissprot Id:
- P26583
- Host:
- Rabbit
- Clonality:
- Polyclonal
- Protein Size (# AA):
- 209
- Molecular Weight:
- 24kDa
- Application:
- WB, IHC
- Partner Proteins:
- AKT1, ARHGEF10L, ATXN1, BCL2, EP300, FXYD3, GADD45GIP1, KAT2B, MAPK1, MED1, NCOA1, NCOA2, NCOA3, NCOR2, NR4A1, PML, RPS6KA1, RPS6KA3, RPS6KA5, RPS6KA6, RXRG, TP53, YWHAZ, AKT1, BCL2, EP300, FXYD3, GADD45GIP1, HIF1A, KAT2B, MAPK8, NCOA1, NCOA3, NCOR2, PML, RPS6KA6, RXRA, RXRG, TP53, VHL
- Immunogen:
- The immunogen for anti-HMGB2 antibody: synthetic peptide directed towards the C terminal of human HMGB2
- Product Format:
- Lyophilized powder
- Purification:
- Affinity Purified
- Complete computational species homology data:
- HMGB2 antibody - C-terminal region (ARP31939_P050)
- Predicted Homology Based on Immunogen Sequence:
- Bovine: 100%; Dog: 100%; Human: 100%; Mouse: 100%; Pig: 100%; Rat: 100%; African clawed frog: 92%; Chicken: 92%
- Datasheets / Downloads:
- Printable datasheet for
anti-HMGB2 antibody
- ARP31939_P050 - Peptide Sequence:
- Synthetic peptide located within the following region: AAYRAKGKSEAGKKGPGRPTGSKKKNEPEDEEEEEEEEDEDEEEEDEDEE
- Blocking Peptide:
- For anti-HMGB2 antibody is Catalog # AAP31939 (Previous Catalog # AAPP02836)
- Key Reference:
- Melvin,V.S., et al., (2004) J. Biol. Chem. 279 (15), 14763-14771
- Reconstitution and Storage:
- Add 50 μl of distilled water. Final anti-HMGB2 antibody concentration is 1 mg/ml in PBS buffer. For longer periods of storage, store at -20°C. Avoid repeat freeze-thaw cycles.
Product Protocols: HMGB2 antibody tested with Human Jurkat Cells (ARP31939_P050)
Aviva Systems Biology is the original manufacturer of this HMGB2 antibody (ARP31939_P050)
Click here to view the HMGB2 antibody Western Blot Protocol
Product Datasheet Link: HMGB2 antibody (ARP31939_P050)
WB Suggested Anti-HMGB2 Antibody Titration: 0.2-1 ug/ml
ELISA Titer: 1:62500
Positive Control: Jurkat
Western Blot image: 
Description of Target: This protein is a member of the non-histone chromosomal high mobility group family. The proteins of this family are chromatin-associated and ubiquitously distributed in the nucleus of higher eukaryotic cells. In vitro studies have demonstrated that this protein is able to efficiently bend DNA and form DNA circles. These studies suggest a role in facilitating cooperative interactions between cis-acting proteins by promoting DNA flexibility. This protein was also reported to be involved in the final ligation step in the DNA end-joining processes of DNA double-strand breaks repair and V(D)J recombination.This gene encodes a member of the non-histone chromosomal high mobility group protein family. The proteins of this family are chromatin-associated and ubiquitously distributed in the nucleus of higher eukaryotic cells. In vitro studies have demonstrated that this protein is able to efficiently bend DNA and form DNA circles. These studies suggest a role in facilitating cooperative interactions between cis-acting proteins by promoting DNA flexibility. This protein was also reported to be involved in the final ligation step in DNA end-joining processes of DNA double-strand breaks repair and V(D)J recombination. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Entrez Gene record to access additional publications.
Questions pertaining to this data can be directed to techsupport@avivasysbio.com
Aviva Systems Biology’s HMGB2 antibody (ARP31939_P050) has been tested using other cell lysates and tissues. To obtain more data about this antibody please email us at info@avivasysbio.com.
To order by phone call us at (888) 880-0001, fax us at (858) 552-6975 or send an email to info@avivasysbio.com. Aviva manufactures this antibody so we can offer the best price. Please contact us to request pricing information.
All of Aviva’s products are guaranteed for the applications and experimental sample types mentioned in the datasheet below. Are you curious if this product will work for you? Please contact us at techsupport@avivasysbio.com
Product Protocols: HMGB2 antibody tested by IHC with human lung (ARP31939)
Aviva Systems Biology is the original manufacturer of this HMGB2 antibody.
Click here to view the HMGB2 antibody Immunohistochemistry (IHC) protocol
Product Datasheet Link: HMGB2 antibody (ARP31939)
IHC Information:
Rabbit Anti-HMGB2 Antibody
Catalog Number: ARP31939
Paraffin Embedded Tissue: Human Lung
Cellular Data: Alveolar cells
Antibody Concentration: 4.0-8.0 ug/ml
Magnification: 400X
IHC Image:
Product Protocols: HMGB2 antibody tested by IHC with human liver (ARP31939)
Aviva Systems Biology is the original manufacturer of this HMGB2 antibody.
Click here to view the HMGB2 antibody Immunohistochemistry (IHC) protocol
Product Datasheet Link: HMGB2 antibody (ARP31939)
IHC Information:
Rabbit Anti-HMGB2 Antibody
Catalog Number: ARP31939
Paraffin Embedded Tissue: Human Liver
Cellular Data: Hepatocytes
Antibody Concentration: 4.0-8.0 ug/ml
Magnification: 400X
IHC Image:
- Protocol:
- Tips Information:
See our General FAQ page.
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Fax:(858) 552-6975
