SNX6 Antibody - C-terminal region (ARP65276_P050)

Catalog No: ARP65276_P050

25 ug of the indicated Human whole cell extracts was loaded onto a 12% SDS-PAGE gel. 1 ug/mL of the antibody was used in this experiment.

Product Info

• Tested Species Reactivity: Human
• Predicted Species Reactivity: Human, Mouse, Rat, Cow, Dog, Guinea Pig, Horse, Rabbit, Zebrafish
• Product Format: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09% (w/v) sodium azide and 2% sucrose.
• Clonality: Polyclonal
• Host: Rabbit
• Application: WB
• Reconstitution and Storage: For short term use, store at 2-8C up to 1 week. For long term storage, store at -20C in small aliquots to prevent freeze-thaw cycles.
• Purification: Affinity Purified
• Predicted Homology Based on Immunogen Sequence: Cow: 100%; Dog: 100%; Guinea Pig: 100%; Horse: 100%; Human: 100%; Mouse: 100%; Rabbit: 100%; Rat: 100%; Zebrafish: 100%
• Peptide Sequence: Synthetic peptide located within the following region: LRESQAAKDLLYRRSRSLVDYENANKALDKARAKNKDVLQAETSQQLCCQ
• Concentration: 0.5 mg/ml
• Blocking Peptide: For anti-SNX6 (ARP65276_P050) antibody is Catalog # AAP65276

Target Info

• Gene Symbol: SNX6
• Gene Full Name: Sorting nexin 6
• Alias Symbols: TFAF2, MSTP010
• NCBI Gene Id: 58533
• Protein Name: Sorting nexin-6
• Description of Target: This gene encodes a member of the sorting nexin family. Members of this family contain a phox (PX) domain, which is a phosphoinositide binding domain, and are involved in intracellular trafficking. This protein associates with the long isoform of the leptin receptor, the transforming growth factor-beta family of receptor serine-threonine kinases, and with receptor tyrosine kinases for platelet-derived growth factor, insulin, and epidermal growth factor. This protein may form oligomeric complexes with family member proteins through interactions of both the PX domain and the coiled coil regions of the molecules. Translocation of this protein from the cytoplasm to the nucleus occurs after binding to proviral integration site 1 protein. This gene results in two transcripts encoding two distinct isoforms.
• Uniprot ID: Q9UNH7
• Protein Accession #: NP_689419
• Nucleotide Accession #: NM_152233
• Protein Size (# AA): 418
• Molecular Weight: 47 kDa
• Protein Interactions: UBC; FAM129B; VPS35; VPS29; RTF1; ATG7; TSNAX; TSN; STAT1; SNX2; SHMT2; SHMT1; PAWR; H3F3A; GTF2A1; ATP6V1C1; APEH; ANP32E; CSNK2A2; SNX1; BRCA1; PHLPP1; COIL; GIT1; ELAVL1; NDEL1; DISC1; TNIK; CALM1; TPT1; SNX6; SNX4; BMPR1B; ACVR2B; ACVRL1; LEPR; TGFBR2