Catalog No: ARP61563_P050
Price: $0.00
SKU
ARP61563_P050
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Datasheets/ManualsPrintable datasheet for anti-PRKAR2A (ARP61563_P050) antibody
Product Info
Tested Species ReactivityHuman, Mouse
Predicted Species ReactivityHuman, Mouse, Rat, Cow, Dog, Guinea Pig, Horse, Pig, Rabbit
Product FormatLiquid. Purified antibody supplied in 1x PBS buffer with 0.09% (w/v) sodium azide and 2% sucrose.
ClonalityPolyclonal
HostRabbit
ApplicationWB
Reconstitution and StorageFor short term use, store at 2-8C up to 1 week. For long term storage, store at -20C in small aliquots to prevent freeze-thaw cycles.
PurificationAffinity Purified
Predicted Homology Based on Immunogen SequenceCow: 100%; Dog: 100%; Guinea Pig: 93%; Horse: 100%; Human: 100%; Mouse: 100%; Pig: 100%; Rabbit: 93%; Rat: 100%
Peptide SequenceSynthetic peptide located within the following region: DILVTKDNQTRSVGQYDNRGSFGELALMYNTPRAATIVATSEGSLWGLDR
Concentration0.5 mg/ml
Blocking PeptideFor anti-PRKAR2A (ARP61563_P050) antibody is Catalog # AAPP47674
Gene SymbolPRKAR2A
Gene Full NameProtein kinase, cAMP-dependent, regulatory, type II, alpha
Alias SymbolsPKR2, PRKAR2
NCBI Gene Id5576
Protein NamecAMP-dependent protein kinase type II-alpha regulatory subunit
Description of TargetcAMP is a signaling molecule important for a variety of cellular functions. cAMP exerts its effects by activating the cAMP-dependent protein kinase, which transduces the signal through phosphorylation of different target proteins. The inactive kinase holoenzyme is a tetramer composed of two regulatory and two catalytic subunits. cAMP causes the dissociation of the inactive holoenzyme into a dimer of regulatory subunits bound to four cAMP and two free monomeric catalytic subunits. Four different regulatory subunits and three catalytic subunits have been identified in humans. The protein encoded by this gene is one of the regulatory subunits. This subunit can be phosphorylated by the activated catalytic subunit. It may interact with various A-kinase anchoring proteins and determine the subcellular localization of cAMP-dependent protein kinase. This subunit has been shown to regulate protein transport from endosomes to the Golgi apparatus and further to the endoplasmic reticulum (ER).
Uniprot IDP13861
Protein Accession #NP_004148
Nucleotide Accession #NM_004157
Protein Size (# AA)404
Molecular Weight44kDa
Protein InteractionsUBC; SUZ12; IMPDH2; GPS1; CSRP1; KPNA6; PRKACB; PRKACA; GCH1; WASF1; VCP; CIRBP; ELAVL1; PJA2; Dynll1; AKAP7; PPP1CB; MYCBPAP; ARFGEF2; AKAP2; RAB32; NBEA; AKAP12; AKAP11; AKAP10; AKAP8; AKAP6; AKAP3; AKAP5; AKAP13; AKAP9; CBFA2T3; SMAD3; AKAP1; CFTR; SMA
  1. What is the species homology for "PRKAR2A Antibody - middle region (ARP61563_P050)"?

    The tested species reactivity for this item is "Human, Mouse". This antibody is predicted to have homology to "Human, Mouse, Rat, Cow, Dog, Guinea Pig, Horse, Pig, Rabbit".

  2. How long will it take to receive "PRKAR2A Antibody - middle region (ARP61563_P050)"?

    This item is available "Domestic: within 1-2 days delivery | International: 1-2 days".

  3. What buffer format is "PRKAR2A Antibody - middle region (ARP61563_P050)" provided in?

    This item is provided in "Liquid. Purified antibody supplied in 1x PBS buffer with 0.09% (w/v) sodium azide and 2% sucrose.".
    Additional format options may be available. For more information please contact info@avivasysbio.com.

  4. What are other names for "PRKAR2A Antibody - middle region (ARP61563_P050)"?

    This target may also be called "PKR2, PRKAR2" in publications.

  5. What is the shipping cost for "PRKAR2A Antibody - middle region (ARP61563_P050)"?

    The shipping cost for this item is $40 within the US. Please contact us for specific shipping prices for international orders.

  6. What is the guarantee for "PRKAR2A Antibody - middle region (ARP61563_P050)"?

    All Aviva products have been through rigorous validations and carry 100% satisfaction guarantee.

  7. Can I get bulk pricing for "PRKAR2A Antibody - middle region (ARP61563_P050)"?

    You can get bulk pricing for this item by going here.

  8. What is the molecular weight of the protein?

    The molecular weight reported by Uniprot for this item is "44kDa".
    Please note observed molecular weights in western blot applications may differ depending on a variety of protein characteristics.

  9. What protocols are available for "PRKAR2A Antibody - middle region (ARP61563_P050)"?

    We may have detailed protocol data avaialble for this item. To learn more, please view the "Protocols & Data" tab on the product page.

  10. What are positive controls for "PRKAR2A"?

    We have listed RNA Seq and gene expression data in the "Target Info" tab. You may be able to find adequate positive controls there.

  11. What are negative controls for "PRKAR2A"?

    We have listed RNA Seq and gene expression data in the "Target Info" tab. You may be able to find adequate positive controls there.

  12. What other proteins interact with "PRKAR2A"?

    This protein has been reported to interact with "Protein Interactions". Please view the "Related Categories" tab on the product page for more information.

  13. What biological processes are associated with "PRKAR2A"?

    This protein has been associated with "Biological Processes". Please view the "Related Categories" tab on the product page for more information.

  14. What cellular components are associated with "PRKAR2A"?

    This protein has been associated with "Cellular Components". Please view the "Related Categories" tab on the product page for more information.

  15. What protein functions are associated with "PRKAR2A"?

    This protein has been associated with "Protein Functions". Please view the "Related Categories" tab on the product page for more information.

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