POLG2 Antibody - N-terminal region (ARP61960_P050)

Catalog No: ARP61960_P050

25 ug of the indicated Human whole cell extracts was loaded onto a 12% SDS-PAGE gel. 4 ug/mL of the antibody was used in this experiment.

WB Suggested Anti-POLG2 Antibody
Titration: 1.0 ug/ml
Positive Control: Fetal kidney

Product Info

• Tested Species Reactivity: Human
• Predicted Species Reactivity: Human
• Product Format: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09% (w/v) sodium azide and 2% sucrose.
• Clonality: Polyclonal
• Host: Rabbit
• Application: WB
• Reconstitution and Storage: For short term use, store at 2-8C up to 1 week. For long term storage, store at -20C in small aliquots to prevent freeze-thaw cycles.
• Purification: Affinity Purified
• Predicted Homology Based on Immunogen Sequence: Human: 100%
• Peptide Sequence: Synthetic peptide located within the following region: KSHAELEGNGEHPEAPGSGEGSEALLEICQRRHFLSGSKQQLSRDSLLSG
• Concentration: 0.5 mg/ml
• Blocking Peptide: For anti-POLG2 (ARP61960_P050) antibody is Catalog # AAP61960 (Previous Catalog # AAPP48301)
• Subunit: gamma-2, mitochondrial

Target Info

• Gene Symbol: POLG2
• Gene Full Name: Polymerase (DNA directed), gamma 2, accessory subunit
• Alias Symbols: HP55, POLB, PEOA4, POLGB, MTPOLB, MTDPS16, POLG-BETA
• NCBI Gene Id: 11232
• Protein Name: DNA polymerase subunit gamma-2, mitochondrial
• Description of Target: This gene encodes the processivity subunit of the mitochondrial DNA polymerase gamma. The encoded protein forms a heterotrimer containing one catalytic subunit and two processivity subunits. This protein enhances DNA binding and promotes processive DNA synthesis. Mutations in this gene result in autosomal dominant progressive external ophthalmoplegia with mitochondrial DNA deletions.
• Uniprot ID: Q9UHN1
• Protein Accession #: NP_009146
• Nucleotide Accession #: NM_007215
• Protein Size (# AA): 485
• Molecular Weight: 55 kDa
• Protein Interactions: PARP1; SUMO1;