GTF2I Antibody - N-terminal region (ARP31910_T100)

Catalog No: ARP31910_T100

WB Suggested Anti-GTF2I Antibody
Titration: 2.5 ug/ml
Positive Control: HepG2 Whole CellThere is BioGPS gene expression data showing that GTF2I is expressed in HepG2

WB Suggested Anti-GTF2I Antibody Titration: 0.2-1 ug/mlELISA Titer: 1:312500Positive Control: HepG2There is BioGPS gene expression data showing that GTF2I is expressed in HepG2

Rabbit Anti-GTF21 Antibody
Catalog Number: ARP31910
Paraffin Embedded Tissue: Human Skin
Cellular Data: Squamous epithelial cells
Antibody Concentration: 4.0-8.0 ug/ml
Magnification: 400X

Rabbit Anti-GTF21 Antibody
Catalog Number: ARP31910
Paraffin Embedded Tissue: Human Pancreas
Cellular Data: Epithelial cells of pancreatic acinus
Antibody Concentration: 4.0-8.0 ug/ml
Magnification: 400X

Product Info

• Tested Species Reactivity: Human
• Predicted Species Reactivity: Human, Mouse, Rat, Cow, Dog, Guinea Pig, Horse, Rabbit
• Product Format: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09% (w/v) sodium azide and 2% sucrose.
• Clonality: Polyclonal
• Host: Rabbit
• Application: IHC, WB
• Reconstitution and Storage: For short term use, store at 2-8C up to 1 week. For long term storage, store at -20C in small aliquots to prevent freeze-thaw cycles.
• Immunogen: The immunogen is a synthetic peptide directed towards the N terminal region of human GTF2I
• Purification: Protein A purified
• Predicted Homology Based on Immunogen Sequence: Cow: 100%; Dog: 100%; Guinea Pig: 100%; Horse: 100%; Human: 100%; Mouse: 100%; Rabbit: 100%; Rat: 100%
• Peptide Sequence: Synthetic peptide located within the following region: ILSPGGSCGPIKVKTEPTEDSGISLEMAAVTVKEESEDPDYYQYNIQGSH
• Concentration: 1.0 mg/ml
• Blocking Peptide: For anti-GTF2I (ARP31910_T100) antibody is Catalog # AAP31910
• Sample Type Confirmation:

  There is BioGPS gene expression data showing that GTF2I is expressed in HepG2

• Reference: Desgranges,Z.P., (2005) Mol. Cell. Biol. 25 (24), 10940-10952

Target Info

• Gene Symbol: GTF2I
• Gene Full Name: General transcription factor IIi
• Alias Symbols: WBS, DIWS, SPIN, IB291, BAP135, BTKAP1, TFII-I, WBSCR6, GTFII-I
• NCBI Gene Id: 2969
• Protein Name: General transcription factor II-I
• Description of Target: GTF2I is a multifunctional phosphoprotein with roles in transcription and signal transduction. It is deleted in Williams-Beuren syndrome, a multisystem developmental disorder caused by the deletion of contiguous genes at chromosome 7q11.23.This gene encodes a multifunctional phosphoprotein with roles in transcription and signal transduction. It is deleted in Williams-Beuren syndrome, a multisystem developmental disorder caused by the deletion of contiguous genes at chromosome 7q11.23. The exon(s) encoding 5' UTR has not been fully defined, but this gene is known to contain at least 34 exons, and its alternative splicing generates 4 transcript variants.
• Uniprot ID: Q75M85
• Protein Accession #: NP_001509
• Nucleotide Accession #: NM_001518
• Protein Size (# AA): 957
• Molecular Weight: 108kDa
• Protein Interactions: TP53; ZMYM3; PIAS2; TUBG1; TRAF6; SUMO2; SUMO3; AP2B1; DPY30; GCC1; MTUS2; MDM2; UBC; SUMO1; RPA3; RPA2; RPA1; EED; RNF2; SUZ12; CTPS2; WARS; RPL28; RAD23B; PRPS2; PRKDC; NUCB1; METTL1; ADSL; FBXO6; UBD; CBX2; TAB2; AP4S1; CBX4; MAPK12; C4BPA; MAP3K3; SLU