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Catalog No: OAEB00589 (Formerly GWB-45B8FD)
Size:100UG
Price: $379.00
SKU
OAEB00589
Availability: Domestic: within 1-2 week delivery | International: 1-2 weeks
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  • $55: Antibody & Protein in US
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Datasheets/ManualsPrintable datasheet for Goat Anti-HYPB / SETD2 (internal region) Antibody (OAEB00589)
Product Info
Predicted Species ReactivityDog|Human|Mouse|Porcine
Product FormatSupplied at 0.5 mg/ml in Tris saline, 0.02% sodium azide, pH7.3 with 0.5% bovine serum albumin. Aliquot and store at -20°C. Minimize freezing and thawing.
ClonalityPolyclonal
HostGoat
ApplicationP-ELISA, FC
Reconstitution and StorageAliquot and store at -20°C. Minimize freezing and thawing.
ImmunogenSETD2
PurificationAmmonium Sulfate Precipitated; Affinity Purified
Peptide SequenceC-ERDPDKQTQNKE
Concentration0.5 mg/ml
Application InfoPeptide ELISA: antibody detection limit dilution 1:128000.
FC: Flow cytometric analysis of HepG2 cells. Recommended concentration: 10 ug/ml Optimal dilutions should be determined by the end user.
ReferenceThis antibody (previous batch) has been successfully used in Western blot on Mouse:
Yi X, Tao Y, Lin X, Dai Y, Yang T, Yue X, Jiang X, Li X, Jiang DS, Andrade KC, Chang J. Histone methyltransferase Setd2 is critical for the proliferation and differentiation of myoblasts. Biochim Biophys Acta. 2017 Apr;1864(4):697-707. PMID: 28130125
Publications

Structural basis of the interaction between SETD2 methyltransferase and hnRNP L paralogs for governing co-transcriptional splicing. Nat Commun. 12, 6452 (2021). 34750379

The methyltransferase SETD2 couples transcription and splicing by engaging mRNA processing factors through its SHI domain. Nat Commun. 12, 1443 (2021) 33664260

Description
Gene SymbolSetd2|SETD2
Gene Full NameSET domain containing 2|SET domain containing 2, histone lysine methyltransferase
Alias Symbols4921524K10Rik;BC031601;HBP231;HIF-1;HIP-1;histone-lysine N-methyltransferase SETD2;HSPC069;huntingtin interacting protein 1;huntingtin yeast partner B;huntingtin-interacting protein B;HYPB;KMT3;KMT3A;LLS;lysine N-methyltransferase 3A;p231HBP;protein-lysine N-methyltransferase SETD2;SET domain-containing protein 2;SET2.
NCBI Gene Id235626|29072
Protein NameHistone-lysine N-methyltransferase SETD2
Uniprot IDQ9BYW2
Protein Accession #NP_054878.3
Molecular Weight231
  1. What is the species homology for "Goat Anti-HYPB / SETD2 (internal region) Antibody (OAEB00589)"?

    The tested species reactivity for this item is "". This antibody is predicted to have homology to "Dog|Human|Mouse|Porcine".

  2. How long will it take to receive "Goat Anti-HYPB / SETD2 (internal region) Antibody (OAEB00589)"?

    This item is available "Domestic: within 1-2 week delivery | International: 1-2 weeks".

  3. What buffer format is "Goat Anti-HYPB / SETD2 (internal region) Antibody (OAEB00589)" provided in?

    This item is provided in "Supplied at 0.5 mg/ml in Tris saline, 0.02% sodium azide, pH7.3 with 0.5% bovine serum albumin. Aliquot and store at -20°C. Minimize freezing and thawing.".
    Additional format options may be available. For more information please contact info@avivasysbio.com.

  4. What are other names for "Goat Anti-HYPB / SETD2 (internal region) Antibody (OAEB00589)"?

    This target may also be called "4921524K10Rik;BC031601;HBP231;HIF-1;HIP-1;histone-lysine N-methyltransferase SETD2;HSPC069;huntingtin interacting protein 1;huntingtin yeast partner B;huntingtin-interacting protein B;HYPB;KMT3;KMT3A;LLS;lysine N-methyltransferase 3A;p231HBP;protein-lysine N-methyltransferase SETD2;SET domain-containing protein 2;SET2." in publications.

  5. What is the shipping cost for "Goat Anti-HYPB / SETD2 (internal region) Antibody (OAEB00589)"?

    The shipping cost for this item is $40 within the US. Please contact us for specific shipping prices for international orders.

  6. What is the guarantee for "Goat Anti-HYPB / SETD2 (internal region) Antibody (OAEB00589)"?

    All Aviva products have been through rigorous validations and carry 100% satisfaction guarantee.

  7. Can I get bulk pricing for "Goat Anti-HYPB / SETD2 (internal region) Antibody (OAEB00589)"?

    You can get bulk pricing for this item by going here.

  8. What is the molecular weight of the protein?

    The molecular weight reported by Uniprot for this item is "231".
    Please note observed molecular weights in western blot applications may differ depending on a variety of protein characteristics.

  9. What protocols are available for "Goat Anti-HYPB / SETD2 (internal region) Antibody (OAEB00589)"?

    We may have detailed protocol data avaialble for this item. To learn more, please view the "Protocols & Data" tab on the product page.

  10. What are positive controls for "Setd2|SETD2"?

    We have listed RNA Seq and gene expression data in the "Target Info" tab. You may be able to find adequate positive controls there.

  11. What are negative controls for "Setd2|SETD2"?

    We have listed RNA Seq and gene expression data in the "Target Info" tab. You may be able to find adequate positive controls there.

  12. What other proteins interact with "Setd2|SETD2"?

    This protein has been reported to interact with "Protein Interactions". Please view the "Related Categories" tab on the product page for more information.

  13. What biological processes are associated with "Setd2|SETD2"?

    This protein has been associated with "Biological Processes". Please view the "Related Categories" tab on the product page for more information.

  14. What cellular components are associated with "Setd2|SETD2"?

    This protein has been associated with "Cellular Components". Please view the "Related Categories" tab on the product page for more information.

  15. What protein functions are associated with "Setd2|SETD2"?

    This protein has been associated with "Protein Functions". Please view the "Related Categories" tab on the product page for more information.

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