WRNIP1 Antibody - N-terminal region (ARP36470_P050)

Catalog No: ARP36470_P050

WB Suggested Anti-WRNIP1 Antibody Titration: 0.2-1 ug/ml
ELISA Titer: 1:312500
Positive Control: HepG2 cell lysate

Sample Type: HeLa cell lysateDilution: 1:1000

Product Info

• Tested Species Reactivity: Human
• Predicted Species Reactivity: Human, Mouse, Rat, Cow, Dog, Pig, Yeast, Zebrafish
• Product Format: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09% (w/v) sodium azide and 2% sucrose.
• Clonality: Polyclonal
• Host: Rabbit
• Application: WB
• Reconstitution and Storage: For short term use, store at 2-8C up to 1 week. For long term storage, store at -20C in small aliquots to prevent freeze-thaw cycles.
• Immunogen: The immunogen is a synthetic peptide directed towards the N terminal region of human WRNIP1
• Purification: Affinity Purified
• Predicted Homology Based on Immunogen Sequence: Cow: 79%; Dog: 100%; Human: 100%; Mouse: 100%; Pig: 79%; Rat: 100%; Yeast: 77%; Zebrafish: 85%
• Peptide Sequence: Synthetic peptide located within the following region: PGAKRRRLSESSALKQPATPTAAESSEGEGEEGDDGGETESRESYDAPPT
• Concentration: 0.5 mg/ml
• Blocking Peptide: For anti-WRNIP1 (ARP36470_P050) antibody is Catalog # AAP36470 (Previous Catalog # AAPP08529)
• Reference: Tsurimoto,T., et al., (2005) Genes Cells 10 (1), 13-22

Target Info

• Gene Symbol: WRNIP1
• Gene Full Name: Werner helicase interacting protein 1
• Alias Symbols: WHIP, FAP93, CFAP93, bA420G6.2
• NCBI Gene Id: 56897
• Protein Name: ATPase WRNIP1
• Description of Target: Werner's syndrome is a rare autosomal recessive disorder characterized by premature aging. The protein encoded by this gene interacts with the N-terminal portion of Werner protein containing the exonuclease domain. This protein shows homology to replication factor C family proteins, and is conserved from E. coli to human. Studies in yeast suggest that this gene may influence the aging process. Two transcript variants encoding different isoforms have been isolated for this gene.Werner's syndrome is a rare autosomal recessive disorder characterized by premature aging. The protein encoded by this gene interacts with the N-terminal portion of Werner protein containing the exonuclease domain. This protein shows homology to replication factor C family proteins, and is conserved from E. coli to human. Studies in yeast suggest that this gene may influence the aging process. Two transcript variants encoding different isoforms have been isolated for this gene.
• Uniprot ID: Q96S55
• Protein Accession #: NP_569079
• Nucleotide Accession #: NM_130395
• Protein Size (# AA): 640
• Molecular Weight: 72kDa
• Protein Interactions: UBC; RNF31; PIN1; ELP2; ELP3; TRIM28; HDAC11; EPAS1; VCP; SRSF4; SMAD2; RAD18; NUP107; WRNIP1; FGFR1OP; POLD1; ABL1; SUMO2; TOLLIP; DDX58; USP11; OSBPL10; USP25; POLD4; POLD2; WRN;