Catalog No: ARP46268_P050
Price: $0.00
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ARP46268_P050
Availability: Domestic: within 1-2 days delivery | International: 1-2 days
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Datasheets/ManualsPrintable datasheet for anti-NDC1 (ARP46268_P050) antibody
Product Info
Tested Species ReactivityHuman
Predicted Species ReactivityHuman, Mouse, Rat, Cow, Dog, Guinea Pig, Horse, Rabbit, Zebrafish
Product FormatLiquid. Purified antibody supplied in 1x PBS buffer with 0.09% (w/v) sodium azide and 2% sucrose.
ClonalityPolyclonal
HostRabbit
ApplicationWB
Reconstitution and StorageFor short term use, store at 2-8C up to 1 week. For long term storage, store at -20C in small aliquots to prevent freeze-thaw cycles.
ImmunogenThe immunogen is a synthetic peptide directed towards the middle region of human TMEM48
PurificationAffinity Purified
Predicted Homology Based on Immunogen SequenceCow: 100%; Dog: 100%; Guinea Pig: 100%; Horse: 100%; Human: 100%; Mouse: 100%; Rabbit: 100%; Rat: 100%; Zebrafish: 100%
Peptide SequenceSynthetic peptide located within the following region: PPIIKYLALQDLMLLSQYSPSRRQEVFSLSQPGGHPHNWTAISRECLNLL
Concentration0.5 mg/ml
Blocking PeptideFor anti-NDC1 (ARP46268_P050) antibody is Catalog # AAP46268 (Previous Catalog # AAPS17511)
Enhanced Validation
WBY
SPR
YCHAROS
ReferenceOlsen,J.V., (2006) Cell 127 (3), 635-648
Publications

Tarazón, E. et al. Heart failure induces significant changes in nuclear pore complex of human cardiomyocytes. PLoS One 7, e48957 (2012). 23152829

Gene SymbolNDC1
Gene Full NameTransmembrane protein 48
Alias SymbolsNET3, TMEM48
NCBI Gene Id55706
Protein NameNucleoporin NDC1
Description of TargetTMEM48 is a component of the nuclear pore complex (NPC), which plays a key role in de novo assembly and insertion of NPC in the nuclear envelope. TMEM48 is required for NPC and nuclear envelope assembly, possibly by forming a link between the nuclear envelope membrane and soluble nucleoporins, thereby anchoring the NPC in the membrane.
Uniprot IDQ9BTX1
Protein Accession #NP_060557
Nucleotide Accession #NM_018087
Protein Size (# AA)674
Molecular Weight76 kDa
Protein InteractionsUBC; Ndc1; NUP93;
  1. What is the species homology for "TMEM48 Antibody - middle region (ARP46268_P050)"?

    The tested species reactivity for this item is "Human". This antibody is predicted to have homology to "Human, Mouse, Rat, Cow, Dog, Guinea Pig, Horse, Rabbit, Zebrafish".

  2. How long will it take to receive "TMEM48 Antibody - middle region (ARP46268_P050)"?

    This item is available "Domestic: within 1-2 days delivery | International: 1-2 days".

  3. What buffer format is "TMEM48 Antibody - middle region (ARP46268_P050)" provided in?

    This item is provided in "Liquid. Purified antibody supplied in 1x PBS buffer with 0.09% (w/v) sodium azide and 2% sucrose.".
    Additional format options may be available. For more information please contact info@avivasysbio.com.

  4. What are other names for "TMEM48 Antibody - middle region (ARP46268_P050)"?

    This target may also be called "NET3, TMEM48" in publications.

  5. What is the shipping cost for "TMEM48 Antibody - middle region (ARP46268_P050)"?

    The shipping cost for this item is $40 within the US. Please contact us for specific shipping prices for international orders.

  6. What is the guarantee for "TMEM48 Antibody - middle region (ARP46268_P050)"?

    All Aviva products have been through rigorous validations and carry 100% satisfaction guarantee.

  7. Can I get bulk pricing for "TMEM48 Antibody - middle region (ARP46268_P050)"?

    You can get bulk pricing for this item by going here.

  8. What is the molecular weight of the protein?

    The molecular weight reported by Uniprot for this item is "76 kDa".
    Please note observed molecular weights in western blot applications may differ depending on a variety of protein characteristics.

  9. What protocols are available for "TMEM48 Antibody - middle region (ARP46268_P050)"?

    We may have detailed protocol data avaialble for this item. To learn more, please view the "Protocols & Data" tab on the product page.

  10. What are positive controls for "NDC1"?

    We have listed RNA Seq and gene expression data in the "Target Info" tab. You may be able to find adequate positive controls there.

  11. What are negative controls for "NDC1"?

    We have listed RNA Seq and gene expression data in the "Target Info" tab. You may be able to find adequate positive controls there.

  12. What other proteins interact with "NDC1"?

    This protein has been reported to interact with "Protein Interactions". Please view the "Related Categories" tab on the product page for more information.

  13. What biological processes are associated with "NDC1"?

    This protein has been associated with "Biological Processes". Please view the "Related Categories" tab on the product page for more information.

  14. What cellular components are associated with "NDC1"?

    This protein has been associated with "Cellular Components". Please view the "Related Categories" tab on the product page for more information.

  15. What protein functions are associated with "NDC1"?

    This protein has been associated with "Protein Functions". Please view the "Related Categories" tab on the product page for more information.

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