RBM8A Antibody - N-terminal region (ARP40576_T100)

Catalog No: ARP40576_T100

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WB Suggested Anti-RBM8A Antibody Titration: 1.25ug/ml
Positive Control: Jurkat cell lysateThere is BioGPS gene expression data showing that RBM8A is expressed in Jurkat

Rabbit Anti-RBM8A Antibody
Catalog Number: ARP40576
Paraffin Embedded Tissue: Human Heart
Cellular Data: Myocardial cells
Antibody Concentration: 4.0-8.0 ug/ml
Magnification: 400X

Rabbit Anti-RBM8A Antibody
Catalog Number: ARP40576
Paraffin Embedded Tissue: Human alveolar cell
Cellular Data: Epithelial cells of renal tubule
Antibody Concentration: 4.0-8.0 ug/ml
Magnification: 400X

Product Info

• Tested Species Reactivity: Human
• Predicted Species Reactivity: Human, Mouse, Rat, Cow, Dog, Horse, Pig, Rabbit, Zebrafish
• Product Format: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09% (w/v) sodium azide and 2% sucrose.
• Clonality: Polyclonal
• Host: Rabbit
• Application: IHC, WB
• Reconstitution and Storage: For short term use, store at 2-8C up to 1 week. For long term storage, store at -20C in small aliquots to prevent freeze-thaw cycles.
• Immunogen: The immunogen is a synthetic peptide directed towards the N terminal region of human RBM8A
• Purification: Protein A purified
• Predicted Homology Based on Immunogen Sequence: Cow: 100%; Dog: 100%; Horse: 100%; Human: 100%; Mouse: 100%; Pig: 82%; Rabbit: 82%; Rat: 100%; Zebrafish: 100%
• Peptide Sequence: Synthetic peptide located within the following region: LHEAGGEDFAMDEDGDESIHKLKEKAKKRKGRGFGSEEGSRARMREDYDS
• Concentration: 1.0 mg/ml
• Blocking Peptide: For anti-RBM8A (ARP40576_T100) antibody is Catalog # AAP40576 (Previous Catalog # AAPP22752)
• Sample Type Confirmation:

  There is BioGPS gene expression data showing that RBM8A is expressed in Jurkat

• Reference: Hsu,Ia.W., (2005) J. Biol. Chem. 280 (41), 34507-34512

Target Info

• Gene Symbol: RBM8A
• Gene Full Name: RNA binding motif protein 8A
• Alias Symbols: TAR, Y14, RBM8, ZNRP, RBM8B, ZRNP1, BOV-1A, BOV-1B, BOV-1C, MDS014, DEL1q21.1, C1DELq21.1
• NCBI Gene Id: 9939
• Protein Name: RNA-binding protein 8A
• Description of Target: RBM8A is a protein with a conserved RNA-binding motif. The protein is found predominantly in the nucleus, although it is also present in the cytoplasm. It is preferentially associated with mRNAs produced by splicing, including both nuclear mRNAs and newly exported cytoplasmic mRNAs. It is thought that the protein remains associated with spliced mRNAs as a tag to indicate where introns had been present, thus coupling pre- and post-mRNA splicing events.This gene encodes a protein with a conserved RNA-binding motif. The protein is found predominantly in the nucleus, although it is also present in the cytoplasm. It is preferentially associated with mRNAs produced by splicing, including both nuclear mRNAs and newly exported cytoplasmic mRNAs. It is thought that the protein remains associated with spliced mRNAs as a tag to indicate where introns had been present, thus coupling pre- and post-mRNA splicing events. Previously, it was thought that two genes encode this protein, RBM8A and RBM8B; it is now thought that the RBM8B locus is a pseudogene. Two alternative start codons result in two forms of the protein, and this gene also uses multiple polyadenylation sites.
• Uniprot ID: Q9Y5S9
• Protein Accession #: NP_005096
• Nucleotide Accession #: NM_005105
• Protein Size (# AA): 174
• Molecular Weight: 19kDa
• Protein Interactions: MAGOHB; MAGOH; UBC; SUZ12; RNF2; PARK2; SRPK2; SRPK1; FBXO25; tat; UPF3B; SMG9; SMG8; PABPC1; UPF2; SMG5; SMG1; RUVBL2; RBM8A; SMG7; EIF4A3; TTI1; RUVBL1; UPF1; NCBP2; TOE1; SF3B2; RPS16; RPL11; HBB; GSPT1; ZFP36L1; UNC119B; SLIRP; LSM2; CIAPIN1; TFCP2L1;