Catalog No: ARP32878_T100
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ARP32878_T100
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Datasheets/ManualsPrintable datasheet for anti-PPARD (ARP32878_T100) antibody
Product Info
Tested Species ReactivityHuman
Predicted Species ReactivityHuman, Mouse, Rat, Cow, Dog, Guinea Pig, Horse, Rabbit, Zebrafish
Product FormatLiquid. Purified antibody supplied in 1x PBS buffer with 0.09% (w/v) sodium azide and 2% sucrose.
ClonalityPolyclonal
HostRabbit
ApplicationWB
Reconstitution and StorageFor short term use, store at 2-8C up to 1 week. For long term storage, store at -20C in small aliquots to prevent freeze-thaw cycles.
ImmunogenThe immunogen is a synthetic peptide directed towards the middle region of human PPARD
PurificationProtein A purified
Predicted Homology Based on Immunogen SequenceCow: 93%; Dog: 93%; Guinea Pig: 93%; Horse: 92%; Human: 100%; Mouse: 92%; Rabbit: 93%; Rat: 100%; Zebrafish: 92%
Peptide SequenceSynthetic peptide located within the following region: NPQVADLKAFSKHIYNAYLKNFNMTKKKARSILTGKASHTAPFVIHDIET
Concentration1.0 mg/ml
Blocking PeptideFor anti-PPARD (ARP32878_T100) antibody is Catalog # AAP32878 (Previous Catalog # AAPP03902)
ReferenceBarish,G.D., et al., (2006) J. Clin. Invest. 116 (3), 590-597
Gene SymbolPPARD
Gene Full NamePeroxisome proliferator-activated receptor delta
Alias SymbolsFAAR, NUC1, NUCI, NR1C2, NUCII, PPARB
NCBI Gene Id5467
Protein NamePeroxisome proliferator-activated receptor delta
Description of TargetPPARD is a member of the peroxisome proliferator-activated receptor (PPAR) family. PPARs are nuclear hormone receptors that bind peroxisome proliferators and control the size and number of peroxisomes produced by cells. PPARs mediate a variety of biological processes, and may be involved in the development of several chronic diseases, including diabetes, obesity, atherosclerosis, and cancer. This protein is a potent inhibitor of ligand-induced transcription activity of PPAR delta and PPAR gamma. It may function as an integrator of transcription repression and nuclear receptor signaling. The expression of this gene is found to be elevated in colorectal cancer cells. The elevated expression can be repressed by adenomatosis polyposis coli (APC), a tumor suppressor protein related to APC/beta-catenin signaling pathway. Knockout studies in mice suggested the role of this protein in myelination of the corpus callosum, lipid metabolism, and epidermal cell proliferation.
Uniprot IDQ03181
Protein Accession #NP_006229
Nucleotide Accession #NM_006238
Protein Size (# AA)441
Molecular Weight49kDa
Protein InteractionsKRTAP10-3; KRTAP10-7; PLA2G4A; CTNNB1; KDM1A; PRMT3; SMAD9; HSP90AA1; TNP1; PSMG1; Nedd4; RANBP9; PRDX6; EIF3I; NCOA1; NR0B2; SHMT2; RXRG; RXRB; RXRA; PROX1; ITGB5; GLUL; RELA; HDAC1; EP300; NCOA2; SRC; SPEN; HDAC7; HDAC3; PEBP1; HDAC2; GADD45G; GADD45B;
  1. What is the species homology for "PPARD Antibody - middle region (ARP32878_T100)"?

    The tested species reactivity for this item is "Human". This antibody is predicted to have homology to "Human, Mouse, Rat, Cow, Dog, Guinea Pig, Horse, Rabbit, Zebrafish".

  2. How long will it take to receive "PPARD Antibody - middle region (ARP32878_T100)"?

    This item is available "Domestic: within 1-2 days delivery | International: 1-2 days".

  3. What buffer format is "PPARD Antibody - middle region (ARP32878_T100)" provided in?

    This item is provided in "Liquid. Purified antibody supplied in 1x PBS buffer with 0.09% (w/v) sodium azide and 2% sucrose.".
    Additional format options may be available. For more information please contact info@avivasysbio.com.

  4. What are other names for "PPARD Antibody - middle region (ARP32878_T100)"?

    This target may also be called "FAAR, NUC1, NUCI, NR1C2, NUCII, PPARB" in publications.

  5. What is the shipping cost for "PPARD Antibody - middle region (ARP32878_T100)"?

    The shipping cost for this item is $40 within the US. Please contact us for specific shipping prices for international orders.

  6. What is the guarantee for "PPARD Antibody - middle region (ARP32878_T100)"?

    All Aviva products have been through rigorous validations and carry 100% satisfaction guarantee.

  7. Can I get bulk pricing for "PPARD Antibody - middle region (ARP32878_T100)"?

    You can get bulk pricing for this item by going here.

  8. What is the molecular weight of the protein?

    The molecular weight reported by Uniprot for this item is "49kDa".
    Please note observed molecular weights in western blot applications may differ depending on a variety of protein characteristics.

  9. What protocols are available for "PPARD Antibody - middle region (ARP32878_T100)"?

    We may have detailed protocol data avaialble for this item. To learn more, please view the "Protocols & Data" tab on the product page.

  10. What are positive controls for "PPARD"?

    We have listed RNA Seq and gene expression data in the "Target Info" tab. You may be able to find adequate positive controls there.

  11. What are negative controls for "PPARD"?

    We have listed RNA Seq and gene expression data in the "Target Info" tab. You may be able to find adequate positive controls there.

  12. What other proteins interact with "PPARD"?

    This protein has been reported to interact with "Protein Interactions". Please view the "Related Categories" tab on the product page for more information.

  13. What biological processes are associated with "PPARD"?

    This protein has been associated with "Biological Processes". Please view the "Related Categories" tab on the product page for more information.

  14. What cellular components are associated with "PPARD"?

    This protein has been associated with "Cellular Components". Please view the "Related Categories" tab on the product page for more information.

  15. What protein functions are associated with "PPARD"?

    This protein has been associated with "Protein Functions". Please view the "Related Categories" tab on the product page for more information.

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