- Description of Target:
- A large protein complex, termed the anaphase-promoting complex (APC), or the cyclosome, promotes metaphase-anaphase transition by ubiquitinating its specific substrates such as mitotic cyclins and anaphase inhibitor, which are subsequently degraded by the 26S proteasome. Biochemical studies have shown that the vertebrate APC contains eight subunits. The composition of the APC is highly conserved in organisms from yeast to humans. The product of this gene is a component of the complex and shares sequence similarity with a recently identified family of proteins called cullins, which may also be involved in ubiquitin-mediated degradation.
- Gene Symbol:
- ANAPC2
- Alias Symbols:
- APC2; RP11-350O14.5
- Protein Accession# :
- NP_037498.1
- Nucleotide Accession#:
- NM_013366.3
- Swissprot Id:
- Q9UJX6
- Sequence:
- This plasmid may represent the whole or partial sequence of the target. Inquire to techsupport@avivasysbio.com for more information.
- Tag:
- None
- Reconstitution and Storage:
- Centrifuge the vials after receiving and add 5 μl ddH2O
- Key Reference:
- N/A
- Datasheets / Downloads:
- ANA11043
- Protocol:
- Tips Information:
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