website statistics
Account Login 

Now Offering Over 102,157 Antibodies & 44,722 Antigens!

TNF Antibody (AMM00036)

  • Catalog#: AMM00036
  • Domestic: within 1-2 days delivery International: 1-2 days
    *** Required Wet/Dry Ice Surcharge will automatically be applied upon checkout for the shipment. See Surcharges
    - Trial Size Available. Trial size is not available for conjugation.
Scroll Horizontally to view all Images
Print Page
100 ul
    $249.00
    In Stock
    Gene Symbol:
    TNF
    NCBI Gene Id:
    7124
    Protein Name:
    Tumor necrosis factor
    Swissprot Id:
    P01375
    Protein Accession #:
    NP_000585
    Nucleotide Accession #:
    NM_00594
    Alias Symbols:
    APC1 protein, TNF superfamily, member 2, TNF, macrophage-derived, monocyte-derived, TNF-a, cachectin, tumor necrosis factor alpha, tumor necrosis factor ligand superfamily member 2, DIF, TNFA, TNFSF2, TNF-alpha
    Replacement Item:
    This antibody may replace item sc-101425 from Santa Cruz Biotechnology.
    Description of Target:
    TNF alpha is a multifunctional proinflammatory cytokine that belongs to the tumor necrosis factor (TNF) superfamily. This cytokine is mainly secreted by macrophages. It can bind to, and thus functions through its receptors TNFRSF1A/TNFR1 and TNFRSF1B/TNFBR. This cytokine is involved in the regulation of a wide spectrum of biological processes including cell proliferation, differentiation, apoptosis, lipid metabolism, and coagulation. This cytokine has been implicated in a variety of diseases, including autoimmune diseases, insulin resistance, and cancer. Knockout studies in mice also suggested the neuroprotective function of this cytokine.
    Protein Size (# AA):
    233
    Molecular Weight:
    26kDa
    Host:
    Mouse
    Clonality:
    Monoclonal
    Application:
    WB
    Tissue Tool:
    Find tissues and cell lines supported by DNA array analysis to express TNF.
    RNA Seq:
    Find tissues and cell lines supported by RNA-seq analysis to express TNF.
    Species Reactivity:
    Human
    Product Format:
    Liquid. Purified antibody supplied in 1x PBS buffer with 0.09% (w/v) sodium azide and 2% sucrose.
    Reconstitution and Storage:
    For short term use, store at 2-8C up to 1 week. For long term storage, store at -20C in small aliquots to prevent freeze-thaw cycles.
    Concentration:
    Batch dependent within range: 100 ul at 0.5 - 1 mg/ml
    Protein Interactions:
    LAMP2; CASP8; RNF8; FADD; RIPK1; TRADD; UBE2N; UBC; TRAF2; TNFRSF1A; RAB5A; HNRNPA1; CHUK; PSMD9; OTULIN; RNF31; TNFRSF1B; NFKBIA; LYN; FYN; YWHAQ; ZFP36; OPTN; RBCK1; IKBKG; TNFAIP3; HNRNPD; ELAVL1; SHARPIN; AGO2; HSPB2; HSPB1; MAP3K7; IKBKB; TAB2; TAB1;
    Datasheets / Downloads:
    Printable datasheet for anti-TNF (AMM00036) antibody
    Isotype:
    Mouse IgG
    Target Reference:
    Juran,B.D., et al., Hepatology 52 (1), 223-229 (2010)
     
    X
    Ask a Question