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Now Offering Over 85,203 Antibodies & 34,301 Antigens!

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100ug
$249.00
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TNF Antibody (AMM00036)

Description of Target:
TNF alpha is a multifunctional proinflammatory cytokine that belongs to the tumor necrosis factor (TNF) superfamily. This cytokine is mainly secreted by macrophages. It can bind to, and thus functions through its receptors TNFRSF1A/TNFR1 and TNFRSF1B/TNFBR. This cytokine is involved in the regulation of a wide spectrum of biological processes including cell proliferation, differentiation, apoptosis, lipid metabolism, and coagulation. This cytokine has been implicated in a variety of diseases, including autoimmune diseases, insulin resistance, and cancer. Knockout studies in mice also suggested the neuroprotective function of this cytokine.
Gene Symbol:
TNF
NCBI Gene Id:
7124
Alias Symbols:
APC1 protein; TNF superfamily; member 2; TNF; macrophage-derived; monocyte-derived; TNF-a; cachectin; tumor necrosis factor alpha; tumor necrosis factor ligand superfamily member 2; DIF; TNFA; TNFSF2; TNF-alpha
Tissue Tool:
Find tissues and cell lines supported to express TNF.
Protein Accession #:
NP_000585
Nucleotide Accession#:
NM_00594
Swissprot Id:
P01375
Host:
Mouse
Protein Name:
Tumor necrosis factor
Protein Size (# AA):
233
Molecular Weight:
26kDa
Application:
WB
Product Format:
Lyophilized powder
Isotype:
Mouse IgG
Datasheets / Downloads:
Printable datasheet for
anti-TNF antibody
- AMM00036
Species Reactivity:
Human
Reconstitution and Storage:
Add 100ul of distilled water. Final anti-TNF antibody concentration is 1 mg/ml in PBS buffer. For longer periods of storage, store at -20°C. Avoid repeat freeze-thaw cycles.
Key Reference:
Juran,B.D., et al., Hepatology 52 (1), 223-229 (2010)
 
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