CREM Antibody - middle region (ARP53594_P050)

Catalog No: ARP53594_P050

Host: Rabbit
Target Name: CREM
Sample Type: Fetal Kidney lysates
Antibody Dilution: 1.0ug/ml

Host: Mouse
Target Name: CREM
Sample Tissue: Mouse Skeletal Muscle
Antibody Dilution: 1ug/ml

Product Info

• Tested Species Reactivity: Human, Mouse
• Predicted Species Reactivity: Human, Mouse, Rat, Cow, Dog, Goat, Guinea Pig, Horse, Rabbit, Sheep, Zebrafish
• Product Format: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09% (w/v) sodium azide and 2% sucrose.
• Clonality: Polyclonal
• Host: Rabbit
• Application: WB
• Reconstitution and Storage: For short term use, store at 2-8C up to 1 week. For long term storage, store at -20C in small aliquots to prevent freeze-thaw cycles.
• Immunogen: The immunogen is a synthetic peptide directed towards the middle region of Human CREM
• Purification: Affinity Purified
• Predicted Homology Based on Immunogen Sequence: Cow: 100%; Dog: 100%; Goat: 100%; Guinea Pig: 100%; Horse: 100%; Human: 100%; Mouse: 100%; Rabbit: 100%; Rat: 100%; Sheep: 100%; Zebrafish: 92%
• Peptide Sequence: Synthetic peptide located within the following region: GVPKIEEERSEEEGTPPSIATMAVPTSIYQTSTGQYTATGDMPTYQIRAP
• Concentration: 0.5 mg/ml
• Blocking Peptide: For anti-CREM (ARP53594_P050) antibody is Catalog # AAP53594

Target Info

• Gene Symbol: CREM
• Gene Full Name: cAMP responsive element modulator
• Alias Symbols: ICER, CREM-2, hCREM-2
• NCBI Gene Id: 1390
• Protein Name: cAMP-responsive element modulator
• Description of Target: This gene encodes a bZIP transcription factor that binds to the cAMP responsive element found in many viral and cellular promoters. It is an important component of cAMP-mediated signal transduction during the spermatogenetic cycle, as well as other complex processes. Alternative promoter and translation initiation site usage allows this gene to exert spatial and temporal specificity to cAMP responsiveness. Multiple alternatively spliced transcript variants encoding several different isoforms have been found for this gene, with some of them functioning as activators and some as repressors of transcription.
• Uniprot ID: Q03060-2
• Protein Size (# AA): 237
• Molecular Weight: 26kDa
• Protein Interactions: CREB1; PIAS3; CASP8AP2; UBE2I; UBC; SP100; ATXN1; EMP3; HHV8GK18_gp81; MAPK3; CREB3L4; HDAC1; CREB3L1; TAF4; CAMK2D; GSK3A; FHL5; GSK3B; KCNIP3; CAMK2G; PRKACA; CSNK1A1; CREBBP; TBP; PRKCA; SPI1; CREM; ATF1; CDC34; CDK1; CSNK2A2; CSNK2A1; CD34;