IL17A Antibody (AMM00030)

Catalog#: AMM00030

• Size: 100ug

rh-IL17

• Description of Target: IL-17 is a proinflammatory cytokine produced by activated T cells. This cytokine regulates the activities of NF-kappaB and mitogen-activated protein kinases. This cytokine can stimulate the expression of IL6 and cyclooxygenase-2 (PTGS2/COX-2), as well as enhance the production of nitric oxide (NO). High levels of this cytokine are associated with several chronic inflammatory diseases including rheumatoid arthritis, psoriasis and multiple sclerosis.
• Gene Symbol: IL17A
• Alias Symbols: IL17; CTLA8; IL-17; IL-17A; IL17A
• Protein Accession#: NP_002181
• Nucleotide Accession#: NM_002190
• Swissprot Id: Q16552
• Host: Mouse
• Protein Size (# AA): 155
• Molecular Weight: 17kDa
• Application: WB
• Product Format: Lyophilized powder
• Isotype: Mouse IgG2a
• Reconstitution and Storage: Add 100ul of distilled water. Final anti-IL17A antibody concentration is 1 mg/ml in PBS buffer. For longer periods of storage, store at -20°C. Avoid repeat freeze-thaw cycles.
• Key Reference: Dodon, M. D., et al. (2004) J. Gen. Virol. 85 (Pt 7): 1921-1932; Rouvier, E., et al.,(1993) J. Immunol. 150 (12): 5445-5456