CCBP2 antibody - N-terminal region (ARP30776_P050)

Catalog#: ARP30776_P050

• Size: 50ug

Human Jurkat

Human Muscle

• Description of Target: CCBP2 is a beta chemokine receptor, which is predicted to be a seven transmembrane protein similar to G protein-coupled receptors. Chemokines and their receptor-mediated signal transduction are critical for the recruitment of effector immune cells to the inflammation site. The expression of this receptor in lymphatic endothelial cells and overexpression in vascular tumors suggested its function in chemokine-driven recirculation of leukocytes and possible chemokine effects on the development and growth of vascular tumors. This receptor appears to bind the majority of beta-chemokine family members; however, its specific function remains unknown.This gene encodes a beta chemokine receptor, which is predicted to be a seven transmembrane protein similar to G protein-coupled receptors. Chemokines and their receptor-mediated signal transduction are critical for the recruitment of effector immune cells to the inflammation site. This gene is expressed in a range of tissues and hemopoietic cells. The expression of this receptor in lymphatic endothelial cells and overexpression in vascular tumors suggested its function in chemokine-driven recirculation of leukocytes and possible chemokine effects on the development and growth of vascular tumors. This receptor appears to bind the majority of beta-chemokine family members; however, its specific function remains unknown. This gene is mapped to chromosome 3p21.3, a region that includes a cluster of chemokine receptor genes.
• Gene Symbol: CCBP2
• Official Gene Full Name: Chemokine binding protein 2
• Alias Symbols: CCR10; CCR9; CMKBR9; D6; MGC126678; MGC138250; hD6
• Protein Accession#: NP_001287
• Nucleotide Accession#: NM_001296
• Swissprot Id: O00590
• Host: Rabbit
• Clonality: Polyclonal
• Protein Size (# AA): 384
• Molecular Weight: 43kDa
• Application: WB, IHC
• Partner Proteins: ADRBK1, ADRBK2, AFP, ARL6IP5, ARRB1, CCL11, CCL13, CCL14, CCL16, CCL2, CCL3, CCL3L1, CCL3L3, CCL4, CCL5, CCL7, CCL8, CCR2, CCR5, CD4, CXCR4, DNM2, GNAI1, GNAI2, GNAI3, GNAO1, GNAQ, JAK1, JAK2, LCK, ORM1, PRAF2, PSMA5, PTK2, PTK2B, STAT1, STAT3, STAT5A, TXK, AFP, ARRB1, CCL3, CCL3L1, CCL5, CD4, CXCR4
• Immunogen: The immunogen for anti-CCBP2 antibody: synthetic peptide directed towards the N terminal of human CCBP2
• Product Format: Lyophilized powder
• Purification: Affinity Purified
• Predicted Homology Based on Immunogen Sequence: Human: 100%
• Peptide Sequence: Synthetic peptide located within the following region: MAATASPQPLATEDADSENSSFYYYDYLDEVAFMLCRKDAVVSFGKVFLP
• Blocking Peptide: For anti-CCBP2 antibody is Catalog # AAP30776 (Previous Catalog # AAPP24009)
• Key Reference: Galliera,E., (2004) J. Biol. Chem. 279 (24), 25590-25597
• Reconstitution and Storage: Add 50 μl of distilled water. Final anti-CCBP2 antibody concentration is 1 mg/ml in PBS buffer. For longer periods of storage, store at -20°C. Avoid repeat freeze-thaw cycles.

Product Protocols: CCBP2 antibody tested with Human Jurkat Cells (ARP30776_P050)

Aviva Systems Biology is the original manufacturer of this CCBP2 antibody (ARP30776_P050)

Click here to view the CCBP2 antibody Western Blot Protocol

Product Datasheet Link: CCBP2 antibody (ARP30776_P050)

WB Suggested Anti-CCBP2 Antibody Titration: 0.2-1 ug/ml
ELISA Titer: 1:62500
Positive Control: Jurkat

Western Blot image:


Description of Target: CCBP2 is a beta chemokine receptor, which is predicted to be a seven transmembrane protein similar to G protein-coupled receptors. Chemokines and their receptor-mediated signal transduction are critical for the recruitment of effector immune cells to the inflammation site. The expression of this receptor in lymphatic endothelial cells and overexpression in vascular tumors suggested its function in chemokine-driven recirculation of leukocytes and possible chemokine effects on the development and growth of vascular tumors. This receptor appears to bind the majority of beta-chemokine family members; however, its specific function remains unknown.This gene encodes a beta chemokine receptor, which is predicted to be a seven transmembrane protein similar to G protein-coupled receptors. Chemokines and their receptor-mediated signal transduction are critical for the recruitment of effector immune cells to the inflammation site. This gene is expressed in a range of tissues and hemopoietic cells. The expression of this receptor in lymphatic endothelial cells and overexpression in vascular tumors suggested its function in chemokine-driven recirculation of leukocytes and possible chemokine effects on the development and growth of vascular tumors. This receptor appears to bind the majority of beta-chemokine family members; however, its specific function remains unknown. This gene is mapped to chromosome 3p21.3, a region that includes a cluster of chemokine receptor genes.

Questions pertaining to this data can be directed to techsupport@avivasysbio.com

Aviva Systems Biology’s CCBP2 antibody (ARP30776_P050) has been tested using other cell lysates and tissues. To obtain more data about this antibody please email us at info@avivasysbio.com.

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Product Protocols: CCBP2 antibody tested by IHC with human muscle (ARP30776)

Aviva Systems Biology is the original manufacturer of this CCBP2 antibody.

Click here to view the CCBP2 antibody Immunohistochemistry (IHC) protocol

Product Datasheet Link: CCBP2 antibody (ARP30776)

IHC Information:

Rabbit Anti-CCBP2 Antibody
Catalog Number: ARP30776
Paraffin Embedded Tissue: Human Muscle
Cellular Data: Skeletal muscle cells
Antibody Concentration: 4.0-8.0 ug/ml
Magnification: 400X

IHC Image: