MSX2 Antibody - N-terminal region (ARP31398_P050)

Catalog No: ARP31398_P050

WB Suggested Anti-MSX2 Antibody Titration: 0.2-1 ug/ml
ELISA Titer: 1:62500
Positive Control: Transfected 293T

Host: Mouse
Target Name: MSX2
Sample Tissue: Mouse Pancreas
Antibody Dilution: 1ug/ml

Sample Type:
MCF7
Primary Antibody Dilution:
4 ug/ml
Secondary Antibody:
Anti-rabbit Alexa 546
Secondary Antibody Dilution:
2 ug/ml
Gene Name:
MSX2

Product Info

• Tested Species Reactivity: Mouse
• Predicted Species Reactivity: Human, Mouse, Rat, Cow, Dog, Horse, Rabbit
• Product Format: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09% (w/v) sodium azide and 2% sucrose.
• Clonality: Polyclonal
• Host: Rabbit
• Application: IF, WB
• Reconstitution and Storage: For short term use, store at 2-8C up to 1 week. For long term storage, store at -20C in small aliquots to prevent freeze-thaw cycles.
• Immunogen: The immunogen is a synthetic peptide directed towards the n terminal region of human MSX2
• Purification: Affinity Purified
• Predicted Homology Based on Immunogen Sequence: Cow: 100%; Dog: 100%; Horse: 100%; Human: 100%; Mouse: 91%; Rabbit: 91%; Rat: 91%
• Peptide Sequence: Synthetic peptide located within the following region: MASPSKGNDLFSPDEEGPAVVAGPGPGPGGAEGAAEERRVKVSSLPFSVE
• Concentration: 0.5 mg/ml
• Blocking Peptide: For anti-MSX2 (ARP31398_P050) antibody is Catalog # AAP31398 (Previous Catalog # AAPP03062)
• Reference: Satoh,K., (2008) Am. J. Pathol. 172 (4), 926-939

Target Info

• Gene Symbol: MSX2
• Gene Full Name: Msh homeobox 2
• Alias Symbols: FPP, MSH, PFM, CRS2, HOX8, PFM1
• NCBI Gene Id: 4488
• Protein Name: Homeobox protein MSX-2
• Description of Target: MSX2 probable play a morphogenetic role. MSX2 may play a role in limb-pattern formation. In osteoblasts, MSX2 suppresses transcription driven by the osteocalcin FGF response element (OCFRE).This gene encodes a member of the muscle segment homeobox gene family. The encoded protein is a transcriptional repressor whose normal activity may establish a balance between survival and apoptosis of neural crest-derived cells required for proper craniofacial morphogenesis. The encoded protein may also have a role in promoting cell growth under certain conditions and may be an important target for the RAS signaling pathways. Mutations in this gene are associated with parietal foramina 1 and craniosynostosis type 2. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Entrez Gene record to access additional publications.
• Uniprot ID: P35548
• Protein Accession #: NP_002440
• Nucleotide Accession #: NM_002449
• Protein Size (# AA): 267
• Molecular Weight: 29kDa
• Protein Interactions: ATXN1; PIAS2; UBC; XRCC5; XRCC6; ZDHHC2; TLE2; TLE1; PPARG; POU2AF1; NR3C1; POLR3D; SPEN; ZBTB17; RUNX2; DLX5; MAGED1; GTF2F2; GTF2F1; MSX1; DLX2; MSX2; CEBPA; PITX2;