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- $55: Antibody & Protein in US
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| Datasheets/Manuals | Printable datasheet for C6 Antibody (OASA01018) |
|---|
| Predicted Species Reactivity | Human |
|---|---|
| Product Format | Liquid. Borate buffered saline |
| Clonality | Monoclonal |
| Clone | 056B-214.2.4.2 |
| Isotype | IgG1 |
| Host | Mouse |
| Application | Enzyme-linked immunosorbent assay|Flow cytometry|Immunohistochemistry-Frozen |
| Additional Information | Histology Positive Control Tissue: Kidney from post streptococcal glomerulonephritis patients. |
| Reconstitution and Storage | -20°C |
| Immunogen | Purified human C6. |
| Purification | Purified IgG prepared by affinity chromatography on Protein A from ascites |
| Concentration | 1 mg/ml |
| Specificity | Mouse anti Human C6 antibody, clone 056B-214.2.4.2 recognizes complement component 6 (C6), a 104 kDa member of the complement C6/C7/C8/C9 family present in blood serum. It also recognizes C6 as a component of the MAC. |
| Reference | 1. DiScipio, R. et al. (1999) Function of the Factor I modules (FIMS) of human complement component C6. J. Biol. Chem. 274: 31811-31818. |
| Gene Symbol | C6 |
|---|---|
| Alias Symbols | C6 |
| NCBI Gene Id | 729 |
| Protein Name | Complement component C6 |
| Description of Target | The factor I modules of C6 bind the C-terminus of hte C5b alpha-chain, anchoring the molecule to the membrane; they also bind complement component 7. This enables the formation of the C5b-7 precursor complex. C5b-7 then functions as a receptor for components C8 and C9 which form the complement membrane attack complex (MAC). Deficiency of C6 results in susceptibility to bacterial infection. |
| Uniprot ID | P13671 |
| Protein Accession # | NP_000056.2 |
| Protein Size (# AA) | 934 |
- Protocol:
- Reconstitution & Storage Instructions
- Western Blotting/Immunoblotting (WB/IB) Protocol
- Immunohistochemistry (IHC) Protocol
- Immunocytochemistry (ICC) Protocol
- Enzyme-Linked ImmunoSorbent Assay (ELISA) Protocol
- Blocking Peptide Competition Protocol (BPCP)
- Immunoprecipitation (IP) Protocol
- Antibody Array (AA) Protocol
- Tips Information:
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See our General FAQ page.
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What is the species homology for "C6 Antibody (OASA01018)"?
The tested species reactivity for this item is "". This antibody is predicted to have homology to "Human".
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How long will it take to receive "C6 Antibody (OASA01018)"?
This item is available "Domestic: within 1-2 weeks delivery | International: 1-2 weeks".
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What buffer format is "C6 Antibody (OASA01018)" provided in?
This item is provided in "Liquid. Borate buffered saline".
Additional format options may be available. For more information please contact info@avivasysbio.com. -
What are other names for "C6 Antibody (OASA01018)"?
This target may also be called "C6" in publications.
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What is the shipping cost for "C6 Antibody (OASA01018)"?
The shipping cost for this item is $40 within the US. Please contact us for specific shipping prices for international orders.
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What is the guarantee for "C6 Antibody (OASA01018)"?
All Aviva products have been through rigorous validations and carry 100% satisfaction guarantee.
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Can I get bulk pricing for "C6 Antibody (OASA01018)"?
You can get bulk pricing for this item by going here.
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What is the molecular weight of the protein?
The molecular weight reported by Uniprot for this item is "".
Please note observed molecular weights in western blot applications may differ depending on a variety of protein characteristics. -
What protocols are available for "C6 Antibody (OASA01018)"?
We may have detailed protocol data avaialble for this item. To learn more, please view the "Protocols & Data" tab on the product page.
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What are positive controls for "C6"?
We have listed RNA Seq and gene expression data in the "Target Info" tab. You may be able to find adequate positive controls there.
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What are negative controls for "C6"?
We have listed RNA Seq and gene expression data in the "Target Info" tab. You may be able to find adequate positive controls there.
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What other proteins interact with "C6"?
This protein has been reported to interact with "Protein Interactions". Please view the "Related Categories" tab on the product page for more information.
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What biological processes are associated with "C6"?
This protein has been associated with "Biological Processes". Please view the "Related Categories" tab on the product page for more information.
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What cellular components are associated with "C6"?
This protein has been associated with "Cellular Components". Please view the "Related Categories" tab on the product page for more information.
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What protein functions are associated with "C6"?
This protein has been associated with "Protein Functions". Please view the "Related Categories" tab on the product page for more information.
