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BCL2 antibody - N-terminal region (AVARP01005_P050)

Description of Target:
The BCL2 gene encodes an integral outer mitochondrial membrane protein that blocks the apoptotic death of some cells such as lymphocytes. Constitutive expression of BCL2, such as in the case of translocation of BCL2 to Ig heavy chain locus, is thought to be the cause of follicular lymphoma.
Gene Symbol:
BCL2
Official Gene Full Name:
B-cell CLL/lymphoma 2
NCBI Gene Id:
596
Alias Symbols:
Bcl-2; PPP1R50
Tissue Tool:
Find tissues and cell lines supported to express BCL2.
Protein Accession #:
NP_000624
Nucleotide Accession#:
NM_000633
Swissprot Id:
P10415
Host:
Rabbit
Clonality:
Polyclonal
Protein Name:
Apoptosis regulator Bcl-2
Protein Size (# AA):
239
Molecular Weight:
26kDa
Application:
IHC, WB
Partner Proteins:
E2F1, E2F3, E2F4, E2F4, E2F4, NRF1, CCNA1, CCNA2, CCNB1, CCNB1, CCNB1, CCNB2, CCNB2, CDKN1A, MDM4, PITPNM1, PKMYT1, WEE1, ABL1, AMPH, APLP2, AR, BIRC5, BRCA1, BRCA2, BUB1, C13orf15, CALD1, CCNA1, CCNA2, CCNB1, CCNB2, CCNE1, CDC25A, CDC25B, CDC25C, CDK1, CDK7, CDKN1A, CDKN3, CDT1, CEP55, CHAF1B, CK
Immunogen:
The immunogen for anti-BCL2 antibody: synthetic peptide directed towards the N terminal of human BCL2
Product Format:
Lyophilized powder
Purification:
Affinity Purified
Complete computational species homology data:
BCL2 antibody - N-terminal region (AVARP01005_P050)
Predicted Homology Based on Immunogen Sequence:
Human: 100%
Species Reactivity:
Human
Datasheets / Downloads:
Printable datasheet for
anti-BCL2 antibody
- AVARP01005_P050
Peptide Sequence:
Synthetic peptide located within the following region: GHTPHPAASRDPVARTSPLQTPAAPGAAAGPALSPVPPVVHLTLRQAGDD
Blocking Peptide:
For anti-BCL2 antibody is Catalog # AAP30327 (Previous Catalog # AAPP00708)
Key Reference:
Chen,R., et al., (2004) J. Cell Biol. 166 (2), 193-203
Reconstitution and Storage:
Add 50 ul of distilled water. Final anti-BCL2 antibody concentration is 1 mg/ml in PBS buffer with 2% sucrose. For longer periods of storage, store at -20C. Avoid repeat freeze-thaw cycles.
 
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