- Gene Symbol:
- NCBI Gene Id:
- Official Gene Full Name:
- B-cell CLL/lymphoma 2
- Protein Name:
- Apoptosis regulator Bcl-2
- Swissprot Id:
- Protein Accession #:
- Nucleotide Accession #:
- Alias Symbols:
- Bcl-2, PPP1R50
- Replacement Item:
- This antibody may replace item sc-130307 from Santa Cruz Biotechnology.
- Description of Target:
- The BCL2 gene encodes an integral outer mitochondrial membrane protein that blocks the apoptotic death of some cells such as lymphocytes. Constitutive expression of BCL2, such as in the case of translocation of BCL2 to Ig heavy chain locus, is thought to be the cause of follicular lymphoma.
- Protein Size (# AA):
- Molecular Weight:
- Affinity Purified
- IHC, WB
- Tissue Tool:
- Find tissues and cell lines supported by DNA array analysis to express BCL2.
- RNA Seq:
- Find tissues and cell lines supported by RNA-seq analysis to express BCL2.
- The immunogen is a synthetic peptide directed towards the N terminal region of human BCL2
- Species Reactivity:
- Predicted Homology Based on Immunogen Sequence:
- Human: 100%
- Complete computational species homology data:
- Anti-BCL2 (AVARP01005_P050)
- Peptide Sequence:
- Synthetic peptide located within the following region: GHTPHPAASRDPVARTSPLQTPAAPGAAAGPALSPVPPVVHLTLRQAGDD
- Product Format:
- Liquid. Purified antibody supplied in 1x PBS buffer with 0.09% (w/v) sodium azide and 2% sucrose.
- Reconstitution and Storage:
- For short term use, store at 2-8C up to 1 week. For long term storage, store at -20C in small aliquots to prevent freeze-thaw cycles.
- Batch dependent within range: 100 ul at 0.5 - 1 mg/ml
- Protein Interactions:
- KEAP1; SQSTM1; BECN1; UBC; TP53BP2; BID; BCL2L1; BCL2; BAX; BAD; ATP2A3; NR4A1; KRAS; PPID; MDM4; BNIP3; BFAR; CDK1; BAG3; RAF1; IKBKG; TP53; PPP3CC; FKBP8; MAPK8; IKBKB; HSP90AA1; HIF1A; CRYAB; CHUK; PML; BRCA1; AMBRA1; ATG12; BIK; CISD2; MEX3D; PPP1CC;
- Blocking Peptide:
- For anti-BCL2 (AVARP01005_P050) antibody is Catalog # AAP30327 (Previous Catalog # AAPP00708)
- Datasheets / Downloads:
- Printable datasheet for anti-BCL2 (AVARP01005_P050) antibody
- Target Reference:
- Chen,R., et al., (2004) J. Cell Biol. 166 (2), 193-203
Aviva Systems Biology is the original manufacturer of this BCL2 antibody (AVARP01005_P050)
Click here to view the BCL2 antibody Western Blot Protocol
Product Datasheet Link: BCL2 antibody (AVARP01005_P050)
WB Suggested Anti-BCL2 Antibody Titration: 0.2-1 ug/ml
Positive Control: Placenta
Western Blot image:
Description of Target: The BCL2 gene encodes an integral outer mitochondrial membrane protein that blocks the apoptotic death of some cells such as lymphocytes. Constitutive expression of BCL2, such as in the case of translocation of BCL2 to Ig heavy chain locus, is thought to be the cause of follicular lymphoma.
Questions pertaining to this data can be directed to firstname.lastname@example.org
Aviva Systems Biology’s BCL2 antibody (AVARP01005_P050) has been tested using other cell lysates and tissues. To obtain more data about this antibody please email us at email@example.com.
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All of Aviva’s products are guaranteed for the applications and experimental sample types mentioned in the datasheet below. Are you curious if this product will work for you? Please contact us at email@example.com
Aviva Systems Biology is the original manufacturer of this BCL2 antibody.
Click here to view the BCL2 antibody Immunohistochemistry (IHC) protocol
Product Datasheet Link: BCL2 antibody (AVARP01005)
Rabbit Anti-BCL2 Antibody
Catalog Number: AVARP01005
Paraffin Embedded Tissue: Human Kidney
Cellular Data: Epithelial cells of renal tubule
Antibody Concentration: 4.0-8.0 ug/ml