- Description of Target:
- Endoglin is a homodimeric transmembrane glycoprotein highly expressed by endothelial cells. It is a component of the transforming growth factor beta receptor complex since it binds TGFB1 and TGFB3 with high affinity. Mutations in the endoglin gene produce hereditary hemorrhagic telangiectasia.
- Gene Symbol:
- Official Gene Full Name:
- NCBI Gene Id:
- Alias Symbols:
- END; ORW; HHT1; ORW1; CD105
- Tissue Tool:
- Find tissues and cell lines supported to express ENG.
- Protein Accession# :
- Nucleotide Accession#:
- Swissprot Id:
- Protein Name:
- Protein Size (# AA):
- Molecular Weight:
- WB, IHC
- Partner Proteins:
- ENG, ACVR1, ACVR2A, BMP2, BMP7, ENG, INHBA, TCTEX1D4, TGFB1, TGFB2, TGFB3, TGFBR1, TGFBR2, TGFBR3, ACVR1, ACVR2A, ACVR2B, BMP2, BMP7, TGFBR1, TGFBR2
- The immunogen for anti-ENG antibody: synthetic peptide directed towards the N terminal of human ENG
- Product Format:
- Lyophilized powder
- Protein A purified
- Complete computational species homology data:
- ENG antibody - N-terminal region (ARP33068_T100)
- Predicted Homology Based on Immunogen Sequence:
- Human: 100%; Mouse: 90%
- Species Reactivity:
- Human, Mouse
- Datasheets / Downloads:
- Printable datasheet for
anti-ENG antibody- ARP33068_T100
- Peptide Sequence:
- Synthetic peptide located within the following region: ILEVHVLFLEFPTGPSQLELTLQASKQNGTWPREVLLVLSVNSSVFLHLQ
- Blocking Peptide:
- For anti-ENG antibody is Catalog # AAP33068 (Previous Catalog # AAPP04101)
- Key Reference:
- Sanz-Rodriguez,F., et al., (2004) J. Biol. Chem. 279 (31), 32858-32868
- Reconstitution and Storage:
- Add 100 ul of distilled water. Final anti-ENG antibody concentration is 1 mg/ml in PBS buffer with 2% sucrose. For longer periods of storage, store at -20C. Avoid repeat freeze-thaw cycles.
Aviva Systems Biology is the original manufacturer of this ENG antibody (ARP33068_T100)
Click here to view the ENG antibody Western Blot Protocol
Product Datasheet Link: ENG antibody (ARP33068_T100)
WB Suggested Anti-ENG Antibody Titration: 2.0ug/ml
Positive Control: HepG2
Western Blot image:
Description of Target: Endoglin is a homodimeric transmembrane glycoprotein highly expressed by endothelial cells. It is a component of the transforming growth factor beta receptor complex since it binds TGFB1 and TGFB3 with high affinity. Mutations in the endoglin gene produce hereditary hemorrhagic telangiectasia.
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Aviva Systems Biology’s ENG antibody (ARP33068_T100) has been tested using other cell lysates and tissues. To obtain more data about this antibody please email us at firstname.lastname@example.org.
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Aviva Systems Biology is the original manufacturer of this ENG antibody.
Click here to view the ENG antibody Immunohistochemistry (IHC) protocol
Product Datasheet Link: ENG antibody (ARP33068)
Rabbit Anti-ENG Antibody
Catalog Number: ARP33068
Paraffin Embedded Tissue: Human Lung
Cellular Data: Alveolar cells
Antibody Concentration: 4.0-8.0 ug/ml