REL Antibody (OASG01834)

Catalog No: OASG01834

Size:100 uL

Western Blot using COLO205

Product Info

• Predicted Species Reactivity: Human
• Product Format: Liquid. 1 mg/mL in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
• Clonality: Polyclonal
• Isotype: IgG
• Host: Rabbit
• Application: WB, IHC
• Reconstitution and Storage: Store at -20C. Avoid repeated freeze/thaw cycles.
• Immunogen: Synthesized peptide derived from human c-Rel around the non-phosphorylation site of S503. Location: 440-520aa.
• Purification: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
• Concentration: 1 mg/ml
• Specificity: c-Rel Polyclonal Antibody detects endogenous levels of c-Rel protein.
• Application Info: WB 1:500-1:2000; IHC 1:100-1:300; ELISA 1:20000;

Target Info

• Gene Symbol: REL
• Gene Full Name: v-rel avian reticuloendotheliosis viral oncogene homolog
• Alias Symbols: C-Rel, HIVEN86A
• NCBI Gene Id: 5966;
• Description of Target: This gene encodes a protein that belongs to the Rel homology domain/immunoglobulin-like fold, plexin, transcription factor (RHD/IPT) family. Members of this family regulate genes involved in apoptosis, inflammation, the immune response, and oncogenic processes. This proto-oncogene plays a role in the survival and proliferation of B lymphocytes. Mutation or amplification of this gene is associated with B-cell lymphomas, including Hodgkin's lymphoma. Single nucleotide polymorphisms in this gene are associated with susceptibility to ulcerative colitis and rheumatoid arthritis. Alternative splicing results in multiple transcript variants encoding different isoforms.
• Uniprot ID: Q04864
• Molecular Weight: 68 kDa