RBBP4 Antibody (OADC00211)

Catalog No: OADC00211

Size:50ug

Western blot analysis using the Aviva monoclonal antibody directed against hRbAp46/48. Western blot was performed using nuclear extracts from HeLa cells (HeLa NE, 20 ug) and the Aviva monoclonal antibody against hRbAp46/48 diluted 1:1,000 in TBS-Tween containing 5% skim milk. The molecular weight marker (in kDa) is shown on the left), the position of the protein of interest is shown on the right.

Product Info

• Predicted Species Reactivity: Human
• Product Format: Liquid. Provided in PBS containing 0.05% azide and 0.05% ProClin 300.
• Clonality: Monoclonal
• Isotype: Isotype: IgG2b
• Host: Mouse
• Conjugation: Unconjugated
• Application: WB
• Reconstitution and Storage: Store at -20C. Avoid repeated freeze/thaw cycles.
• Purification: Protein G purified
• Concentration: 2 mg/mL
• Preservative: 0.05% Sodium Azide and 0.05% ProClin 300.
• Specificity: Mouse monoclonal antibody raised against SMARCA5
• Application Info: Western Blotting: 1:1,000

Target Info

• Gene Symbol: RBBP4
• Gene Full Name: retinoblastoma binding protein 4
• Alias Symbols: NURF55, RBAP48, lin-53
• NCBI Gene Id: 5928;
• Protein Name: histone-binding protein RBBP4
• Description of Target: This gene encodes a ubiquitously expressed nuclear protein which belongs to a highly conserved subfamily of WD-repeat proteins. It is present in protein complexes involved in histone acetylation and chromatin assembly. It is part of the Mi-2 complex which has been implicated in chromatin remodeling and transcriptional repression associated with histone deacetylation. This encoded protein is also part of co-repressor complexes, which is an integral component of transcriptional silencing. It is found among several cellular proteins that bind directly to retinoblastoma protein to regulate cell proliferation. This protein also seems to be involved in transcriptional repression of E2F-responsive genes. Three transcript variants encoding different isoforms have been found for this gene.
• Uniprot ID: Q09028
• Protein Accession #: NP_001128727.1
• Nucleotide Accession #: NM_001135255.1