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Catalog No: OAEC04264
Size:100 ug/100 ul
Price: $249.00
SKU
OAEC04264
Availability: Domestic: within 2-3 weeks delivery | International: 2-3 weeks
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  • $55: Antibody & Protein in US
  • $55 + $25/Kit in US
  • Contact us for international orders.
Datasheets/ManualsPrintable datasheet for anti-RB1 (OAEC04264) antibody
Product Info
Predicted Species ReactivityHuman
Product FormatAscitic fluid containing 0.03% sodium azide
ClonalityMonoclonal
Clone7E4B8
IsotypeIgG1
HostMouse
ApplicationIHC
Reconstitution and StorageStore at 4C, for long term storage, store at -20C.
ImmunogenPurified recombinant fragment of human RB expres sed in EColi.
Concentration1 mg/ml
Application InfoIHC: 1/200 - 1/1000
ELISA: 1/10000
Gene SymbolRB1
Gene Full Nameretinoblastoma 1
Alias SymbolsRB, pRb, OSRC, pp110, p105-Rb, PPP1R130, p110-RB1
NCBI Gene Id5925
Description of TargetThe Rb protein regulates differentiation, apoptosis, and cell cycle control by coordinating the cell cycle at G1-S with transcriptional machinery. During G1, cyclin D-dependent kinase-mediated phosphorylation of Rb at Ser-795 marks the conversion of Rb from a transcriptionally repressive, hypophosphorylated state to an inactive, phosphorylated state, which may be sustained through mitosis by differential phosphorylation of up to 16 putative serine or threonine residues. Pediatric cancer retinoblastoma and the formation of other human tumors can be attributed to mutations in the retinoblastoma tum or suppressor gene(Rb).
Uniprot IDP06400
  1. What is the species homology for "RB1 Antibody (OAEC04264)"?

    The tested species reactivity for this item is "". This antibody is predicted to have homology to "Human".

  2. How long will it take to receive "RB1 Antibody (OAEC04264)"?

    This item is available "Domestic: within 2-3 weeks delivery | International: 2-3 weeks".

  3. What buffer format is "RB1 Antibody (OAEC04264)" provided in?

    This item is provided in "Ascitic fluid containing 0.03% sodium azide".
    Additional format options may be available. For more information please contact info@avivasysbio.com.

  4. What are other names for "RB1 Antibody (OAEC04264)"?

    This target may also be called "RB, pRb, OSRC, pp110, p105-Rb, PPP1R130, p110-RB1" in publications.

  5. What is the shipping cost for "RB1 Antibody (OAEC04264)"?

    The shipping cost for this item is $40 within the US. Please contact us for specific shipping prices for international orders.

  6. What is the guarantee for "RB1 Antibody (OAEC04264)"?

    All Aviva products have been through rigorous validations and carry 100% satisfaction guarantee.

  7. Can I get bulk pricing for "RB1 Antibody (OAEC04264)"?

    You can get bulk pricing for this item by going here.

  8. What is the molecular weight of the protein?

    The molecular weight reported by Uniprot for this item is "".
    Please note observed molecular weights in western blot applications may differ depending on a variety of protein characteristics.

  9. What protocols are available for "RB1 Antibody (OAEC04264)"?

    We may have detailed protocol data avaialble for this item. To learn more, please view the "Protocols & Data" tab on the product page.

  10. What are positive controls for "RB1"?

    We have listed RNA Seq and gene expression data in the "Target Info" tab. You may be able to find adequate positive controls there.

  11. What are negative controls for "RB1"?

    We have listed RNA Seq and gene expression data in the "Target Info" tab. You may be able to find adequate positive controls there.

  12. What other proteins interact with "RB1"?

    This protein has been reported to interact with "Protein Interactions". Please view the "Related Categories" tab on the product page for more information.

  13. What biological processes are associated with "RB1"?

    This protein has been associated with "Biological Processes". Please view the "Related Categories" tab on the product page for more information.

  14. What cellular components are associated with "RB1"?

    This protein has been associated with "Cellular Components". Please view the "Related Categories" tab on the product page for more information.

  15. What protein functions are associated with "RB1"?

    This protein has been associated with "Protein Functions". Please view the "Related Categories" tab on the product page for more information.

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