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50 ug
$570.00
In Stock

Rabbit Anti Human Interleukin-1RA:Biotin Antibody (50 ug)

Rabbit Anti Human Interleukin-1RA:Biotin
Description of Target:
Rabbit Anti Human Interleukin-1RA:Biotin
NCBI Gene Id:
3557
Tissue Tool:
Find tissues and cell lines supported to express IL1RN.
Protein Accession #:
NP_000568.1
Swissprot Id:
P18510
Host:
Rabbit
Clonality:
Polyclonal
Protein Name:
Interleukin-1 receptor antagonist protein
Specificity:
This product specifically recognises human Interleukin-1 receptor antagonist (IL-1RA), a naturally occurring inflammatory inhibitor protein, produced by monocytes, macrophages, neutrophils, corneal epithelial cells and fibroblasts, which inhibits the activity of IL-1 alpha and IL-1 beta, by competitively blocking binding to cell surface receptors for IL-1.

Genetic variations in IL-1RA gene (IL1RN) are associated with susceptibility to microvascular complications of diabetes type 4 (MVCD4), and IL-1RA has therapeutic applications in rheumatoid arthritis, asthma, psoriasis, sepsis, chronic myelogenous leukaemia and inflammatory bowel disease.

Application:
ELISA, WB
Conjugation:
Biotin Conjugated
Immunogen:
Recombinant human IL-1RA (Catalog No. OPSA10975)
Product Format:
Lyophilized
Concentration:
IgG concentration 0.1mg/ml after reconstitution
Isotype:
Polyclonal IgG
Predicted Homology Based on Immunogen Sequence:
Human
Species Reactivity:
Human
Datasheets / Downloads:
OASA11646
Applications Info:
ELISA: Suggested dilution- 0.25-1.0 ug/ml; This biotinylated human IL-1RA antibody may be used in a direct ELISA or as the detection reagent in a sandwich ELISA with a purified human IL-1RA antibody (Catalog No. OASA11645) as the capture reagent and recombinant human IL-1RA (Catalog No. OPSA10975) as the standard.

Western Blot: Suggested dilution- 0.1-0.2 ug/ml;  This biotinylated human IL-1RA antibody may be used in Western Blotting applications under either reducing or non-reducing conditions with recombinant human IL-1RA (Catalog No. OPSA10975) as the positive control.
Additional Information:
Antiserum Preparation: Antiserum to human IL-1RA were raised by repeated immunisation of rabbits with highly purified antigen. Purified IgG was prepared from whole serum by affinity chromatography.
:::
Buffer Solutions: Phosphate buffered saline
Reconstitution and Storage:
Reconstitution: Reconstitute with 0.5ml sterile PBS containing 0.1% bovine serum albumin
Care should be taken during reconstitution as the protein may appear as a film at the bottom of the vial. Aviva Systems Biology recommend that the vial is gently mixed after reconstitution. For long term storage the addition of 0.09% sodium azide is recommended.
 
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