RAB3GAP2 Antibody (OAAF04114)

Catalog No: OAAF04114 (Formerly GWB-ASE908)

Size:100 ug

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Western blot analysis of extracts from COS cells, using RAB3GAP2 Antibody. The lane on the right is treated with the synthesized peptide.

Immunohistochemistry analysis of paraffin-embedded human breast carcinoma tissue, using RAB3GAP2 Antibody. The picture on the right is treated with the synthesized peptide.

Product Info

• Predicted Species Reactivity: Human|Monkey|Mouse|Rat
• Product Format: Liquid
• Clonality: Polyclonal
• Host: Rabbit
• Application: Enzyme-linked immunosorbent assay|Immunofluorescence|Immunohistochemistry|Immunohistochemistry-Paraffin|Western blot
• Reconstitution and Storage: -20°C
• Immunogen: The antiserum was produced against synthesized peptide derived from human RAB3GAP2.
• Purification: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
• Specificity: RAB3GAP2.RAB3GAP2 antibody detects endogenous levels of total RAB3GAP2 protein.
• Formulation: Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
• Dilution: The optimal working dilution should be determined by the end user.
• Application Info: WB: 1:500~1:3000; IHC: 1:50~1:100; ELISA: 1:40000
• Reference: Nagano F., J. Biol. Chem. 273:24781-24785(1998).
  Xu X., Submitted (MAY-2000) to the EMBL/GenBank/DDBJ databases.
  Nagase T., DNA Res. 5:355-364(1998).

Target Info

• Gene Symbol: RAB3GAP2
• Gene Full Name: RAB3 GTPase activating non-catalytic protein subunit 2
• Alias Symbols: MARTS1;p150;RAB3 GTPase activating protein subunit 2 (non-catalytic);rab3 GTPase-activating protein 150 kDa subunit;rab3 GTPase-activating protein non-catalytic subunit;rab3-GAP p150;rab3-GAP regulatory subunit;RAB3GAP150;RAB3-GAP150;RGAP-iso;SPG69;WARBM2.
• NCBI Gene Id: 25782
• Protein Name: Rab3 GTPase-activating protein non-catalytic subunit
• Description of Target: Regulatory subunit of a GTPase activating protein that has specificity for Rab3 subfamily (RAB3A, RAB3B, RAB3C and RAB3D). Rab3 proteins are involved in regulated exocytosis of neurotransmitters and hormones. Rab3 GTPase-activating complex specifically converts active Rab3-GTP to the inactive form Rab3-GDP. Required for normal eye and brain development. May participate in neurodevelopmental processes such as proliferation, migration and differentiation before synapse formation, and non-synaptic vesicular release of neurotransmitters.
• Uniprot ID: Q9H2M9
• Protein Accession #: NP_036546.2
• Molecular Weight: 155 kDa