PTGR1 Antibody - middle region (OAAB03341)

Catalog No: OAAB03341

Size:400ul

PTGR1 Antibody (Center) western blot analysis in mouse heart tissue lysates (15ug/lane).This demonstrates the PTGR1 antibody detected PTGR1 protein (arrow).

Product Info

• Predicted Species Reactivity: Human, Mouse
• Product Format: LiquidPBS with 0.09% (W/V) sodium azide.
• Clonality: Polyclonal
• Isotype: Rabbit Ig
• Host: Rabbit
• Application: WB, ELISA
• Additional Information: Cellular Location: Cytoplasm.
  Tissue Location: High expression in the kidney, liver, and intestine but not in leukocytes.
• Reconstitution and Storage: Maintain refrigerated at 2-8C for up to 2 weeks. For long term storage store at -20C in small aliquots to prevent freeze-thaw cycles.
• Immunogen: This PTGR1 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 177-205 amino acids from the Central region of human PTGR1.
• Purification: This antibody is purified through a protein A column, followed by peptide affinity purification.
• Predicted Homology Based on Immunogen Sequence: Human; Mouse
• Concentration: 0.5 mg/ml
• Application Info: WB: 1:1000
• Publications:

  Vitturi, D. A. et al. Modulation of nitro-fatty acid signaling: prostaglandin reductase-1 is a nitroalkene reductase. J. Biol. Chem. 288, 25626-37 (2013). 23878198

Target Info

• Gene Symbol: PTGR1
• Alias Symbols: PGR1, DIG-1, ZADH3, LTB4DH
• NCBI Gene Id: 22949
• Protein Name: Prostaglandin reductase 1
• Description of Target: Functions as 15-oxo-prostaglandin 13-reductase and acts on 15-oxo-PGE1, 15-oxo-PGE2 and 15-oxo-PGE2-alpha. Has no activity towards PGE1, PGE2 and PGE2-alpha (By similarity). Catalyzes the conversion of leukotriene B4 into its biologically less active metabolite, 12-oxo-leukotriene B4. This is an initial and key step of metabolic inactivation of leukotriene B4.
• Uniprot ID: Q14914
• Protein Accession #: NP_001139580.1
• Molecular Weight: 36 kDa