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Catalog No: OPCD06456
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OPCD06456
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Datasheets/ManualsPrintable datasheet for PSMC6 Recombinant Protein (OPCD06456)
Product Info
Predicted Species ReactivityHomo sapiens|Human
Product FormatFreeze-dried Powder. PBS, pH7.4, containing 0.01% SKL, 5% Trehalose.
ConjugationUnconjugated
ApplicationPositive control|Sodium sodecyl sulfate - polyacrylamide gel electrophoresis|Western blot
Additional InformationEndotoxin Level: < 1.0 EU per 1 ug (determined by the LAL method)
Isoelectric Point: 8.1
::Residues: Ala2-Val403
::Subcellular Location: Cytoplasm. Nucleus
Reconstitution and Storage2°C to 8°C|-80°C
Concentration200 ug/mL (prior to lyoph)
Purity> 90%
SourceE.coli
TagN-terminal His Tag
Gene SymbolPSMC6
Gene Full Nameproteasome 26S subunit, ATPase 6
Alias Symbols26S proteasome AAA-ATPase subunit RPT4;26S proteasome regulatory subunit 10B;p42;proteasome (prosome, macropain) 26S subunit, ATPase, 6;Proteasome 26S subunit ATPase 6;proteasome subunit p42;RPT5;SUG2.
NCBI Gene Id5706
Protein Name26S proteasome regulatory subunit 10B
Description of TargetComponent of the 26S proteasome, a multiprotein complex involved in the ATP-dependent degradation of ubiquitinated proteins. This complex plays a key role in the maintenance of protein homeostasis by removing misfolded or damaged proteins, which could impair cellular functions, and by removing proteins whose functions are no longer required. Therefore, the proteasome participates in numerous cellular processes, including cell cycle progression, apoptosis, or DNA damage repair. PSMC6 belongs to the heterohexameric ring of AAA (ATPases associated with diverse cellular activities) proteins that unfolds ubiquitinated target proteins that are concurrently translocated into a proteolytic chamber and degraded into peptides.
Uniprot IDP62333
Protein Accession #NP_002797.3
Nucleotide Accession #NM_002806.3
Protein Size (# AA)Ala2~Val403
Molecular Weight46kDa
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