PSAT1 Antibody - N-terminal region (ARP46303_P050)

Catalog No: ARP46303_P050

Host: Rabbit
Target Name: PSAT1
Sample Tissue: Human Fetal Kidney
Antibody Dilution: 1.0ug/ml

Human kidney

Rabbit Anti-PSAT1 antibody
Catalog Number: ARP46303
Formalin Fixed Paraffin Embedded Tissue: Human Brain, Cortex
Primary antibody Concentration: 1:100
Secondary Antibody: Donkey anti-Rabbit-Cy3
Secondary Antibody Concentration: 1:200
Magnification: 20x
Exposure Time: 0.5-2.0sec

Rabbit Anti-PSAT1 antibody
Catalog Number: ARP46303
Formalin Fixed Paraffin Embedded Tissue: Human Spleen
Primary antibody Concentration: 1:100
Secondary Antibody: Donkey anti-Rabbit-Cy3
Secondary Antibody Concentration: 1:200
Magnification: 20x
Exposure Time: 0.5-2.0sec

Product Info

• Tested Species Reactivity: Human
• Predicted Species Reactivity: Human, Mouse, Rat, Cow, Dog, Guinea Pig, Horse, Rabbit, Zebrafish
• Product Format: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09% (w/v) sodium azide and 2% sucrose.
• Clonality: Polyclonal
• Host: Rabbit
• Application: IHC, WB
• Additional Information: IHC Information: Lane A: Marker. Lane B: HepG2 cell lysate. Antibody concentration: 1.0 ug/ml. Gel concentration: 12%.
• Reconstitution and Storage: For short term use, store at 2-8C up to 1 week. For long term storage, store at -20C in small aliquots to prevent freeze-thaw cycles.
• Immunogen: The immunogen is a synthetic peptide directed towards the N terminal region of human PSAT1
• Purification: Affinity Purified
• Predicted Homology Based on Immunogen Sequence: Cow: 100%; Dog: 100%; Guinea Pig: 100%; Horse: 100%; Human: 100%; Mouse: 100%; Rabbit: 100%; Rat: 100%; Zebrafish: 86%
• Peptide Sequence: Synthetic peptide located within the following region: ADYVVTGAWSAKAAEEAKKFGTINIVHPKLGSYTKIPDPSTWNLNPDASY
• Concentration: 0.5 mg/ml
• Blocking Peptide: For anti-PSAT1 (ARP46303_P050) antibody is Catalog # AAP46303 (Previous Catalog # AAPS17901)
• Sample Type Confirmation:

  PSAT1 is supported by BioGPS gene expression data to be expressed in HepG2

• Reference: Baek,J.Y., Biochem. J. 373 (PT 1), 191-200 (2003)
• Publications:

  Clinical Implication of Serine Metabolism-Associated Enzymes in Colon Cancer. Oncology. 89, 351-9 (2015). 26439504

  Yang, Y. et al. PSAT1 regulates cyclin D1 degradation and sustains proliferation of non-small cell lung cancer cells. Int. J. Cancer (2014). doi:10.1002/ijc.29150 25142862

Target Info

• Gene Symbol: PSAT1
• Gene Full Name: Phosphoserine aminotransferase 1
• Alias Symbols: PSA, EPIP, NLS2, PSAT, PSATD
• NCBI Gene Id: 29968
• Protein Name: Phosphoserine aminotransferase
• Description of Target: PSAT1 is likely a phosphoserine aminotransferase, based on similarity to proteins in mouse, rabbit, and Drosophila.The protein encoded by this gene is likely a phosphoserine aminotransferase, based on similarity to proteins in mouse, rabbit, and Drosophila. Alternative splicing of this gene results in two transcript variants encoding different isoforms.
• Uniprot ID: Q9Y617
• Protein Accession #: NP_478059
• Nucleotide Accession #: NM_058179
• Protein Size (# AA): 370
• Molecular Weight: 40kDa
• Protein Interactions: UBC; NEDD8; PPID; PNP; HPRT1; UBD; BAG3; PSMD10; HSP90AB1; HSP90AA1; CEBPE; TUBB6; THADA; KIAA1598; AHCYL1; TTC1; TALDO1; STAT6; RAC1; FH; APP; ACAT2; CDK2; MAPK6;