TARDBP Protein Lysate (GST tagged)(expressed in E. coli)(200ug)

Catalog#: APL00003

• Size: 200ug

• Description of Target: PPIA is a member of the peptidyl-prolyl cis-trans isomerase (PPIase) family. PPIases catalyze the cis-trans isomerization of proline imidic peptide bonds in oligopeptides and accelerate the folding of proteins. PPIA is a cyclosporin binding-protein and may play a role in cyclosporin A-mediated immunosuppression. The protein can also interact with several HIV proteins, including p55 gag, Vpr, and capsid protein, and has been shown to be necessary for the formation of infectious HIV virions.This gene encodes a member of the peptidyl-prolyl cis-trans isomerase (PPIase) family. PPIases catalyze the cis-trans isomerization of proline imidic peptide bonds in oligopeptides and accelerate the folding of proteins. The encoded protein is a cyclosporin binding-protein and may play a role in cyclosporin A-mediated immunosuppression. The protein can also interact with several HIV proteins, including p55 gag, Vpr, and capsid protein, and has been shown to be necessary for the formation of infectious HIV virions. Multiple pseudogenes that map to different chromosomes have been reported. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Entrez Gene record to access additional publications.
• Gene Symbol: TARDBP
• Alias Symbols: TDP-43; ALS10
• Protein Accession#: NP_031401
• Nucleotide Accession#: NM_007375
• Swissprot Id: Q13148
• Protein Size (# AA): 414
• Molecular Weight: 45kDa
• Partner Proteins: BRF1, DEDD2, GTF3C5, TBP, BRF1, DEDD, DEDD2, GTF3C2, GTF3C4, MYC, PLK1, POLR3C, RPAP2, TBP
• Tag: GST
• Quality Control: This product was tested on western blot.
• Reconstitution and Storage: Add 100ul of distilled water. Final concentration is 1 mg/ml. For longer periods of storage, store at -20°C. Avoid repeat freeze-thaw cycles.
• Additional Information: Buffer Formulation: 0.1M Tris-HCl (pH 6.8) buffer containing 0.2M DTT, 4% SDS, 0.2% Bromophenol blue and 20% Sucrose.
• Key Reference: Kabashi,E., (2008) Nat. Genet. 40 (5), 572-574