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Now Offering Over 48,216 Antibodies & 21,887 Antigens!

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2 ug
$80.00
In Stock

Recombinant IL-2 (OPSD00056)

Interleukin-21 (IL-21) is a member of the common gamma-chain family of cytokines (includes IL-2, IL-4, IL-7, IL-9, IL-13, and IL-15) and is expressed by activated CD4+ T cells. IL-21 has a private receptor known as IL-21R, which is expressed on T, B, and NK cells. Within the B cell lineage, IL-21 regulates IgG1 production and coope es with IL-4 for the production of multiple Ab classes in vivo. Initial studies have demonst ed that IL-21 has pleiotropic effects on the prolife ion, differentiation, and effector functions of B, T, natural killer, and dendritic cells. Recombinant IL-21 is a nonglycosylated Protein, containing 133 amino acids, with a total molecular weight of 15.5 kDa.
Formulation:
Recombinant IL-21 is lyopohilized from 20 mM Na2PO4, pH 7.5.Lyophilized product is very stable at -20 C. Reconstituted material should be aliquoted and frozen at -20 C. It is recommended that a carrier Protein (0.1% HSA or BSA) is added for long term storage.
Purity:
(typically >= 95%) determined by:HPLC, Reducing and Non-reducing SDS-PAGE, UV spectroscopy at 280 nm
Biological Activity:
The activity is determined by the dose-dependent stimulation of Mino cells and is typcially less than 0.1-0.6 ng/mL.
Source:
E.coli
Additional Information:
AA Sequence: MQDRHMIRMR QLIDIVDQLK NYVNDLVPEF LPAPEDVETN CEWSAFSCFQ KAQLKSANTG NNERIINVSI KKLKRKPPST NAGRRQKHRL TCPSCDSYEK KPPKEFLERF KSLLQKMIHQ HLSSRTHGSE DS
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Endotoxin Level: Measured by kinetic LAL analysis and is typically =< 1 EU/ug Protein.
Physical State: Sterile filtered white lyophilized (freeze-dried) powder.
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Accession Number: Q9HBE4
Reconstitution and Storage:
Centrifuge vial before opening. When reconstituting the product, gently pipet and wash down the sides of the vial to ensure full recovery of the Protein into solution. It is recommended to reconstitute the lyophilized product with sterile water at a concent ion of 0.1 mg/mL, which can be further diluted into other aqueous solutions.
Datasheets / Downloads:
OPSD00056