BEST1 Protein Lysate (GST tagged) (Expressed in bacteria) (200ug)

Catalog#: APL10166

• Size: 200ug

• Description of Target: This gene encodes a member of the bestrophin gene family. This small gene family is characterized by proteins with a highly conserved N-terminus with four to six transmembrane domains. Bestrophins may form chloride ion channels or may regulate voltage-gated L-type calcium-ion channels. Bestrophins are generally believed to form calcium-activated chloride-ion channels in epithelial cells but they have also been shown to be highly permeable to bicarbonate ion transport in retinal tissue. Mutations in this gene are responsible for juvenile-onset vitelliform macular dystrophy (VMD2), also known as Best macular dystrophy, in addition to adult-onset vitelliform macular dystrophy (AVMD) and other retinopathies. Alternative splicing results in multiple variants encoding distinct isoforms.
• Gene Symbol: BEST1
• Alias Symbols: ARB; BMD; BEST; RP50; VMD2; TU15B
• Protein Accession#: NP_004174
• Nucleotide Accession#: BC015220
• Swissprot Id: O76090
• Molecular Weight: 49
• Tag: GST in N-terminal
• Quality Control: This product was tested on western blot.
  Application : Western blot standard.
  Observed Molecular Weight: 48
  Expression system : Bacteria
• Reconstitution and Storage: Add 200ul of distilled water. Final concentration is 1 mg/ml. For longer periods of storage, store at -20°C. Avoid repeat freeze-thaw cycles.
• Key Reference: N/A