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Catalog No: ARP73821_P050
Price: $0.00
SKU
ARP73821_P050
Availability: Domestic: within 1-2 days delivery | International: 1-2 days
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  • $55: Antibody & Protein in US
  • $55 + $25/Kit in US
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Datasheets/ManualsPrintable datasheet for anti-DFFB (ARP73821_P050) antibody
Product Info
Tested Species ReactivityHuman
Predicted Species ReactivityHuman
Product FormatLiquid. Purified antibody supplied in 1x PBS buffer with 0.09% (w/v) sodium azide and 2% sucrose.
ClonalityPolyclonal
HostRabbit
ApplicationWB
Reconstitution and StorageFor short term use, store at 2-8C up to 1 week. For long term storage, store at -20C in small aliquots to prevent freeze-thaw cycles.
ImmunogenThe immunogen is a synthetic peptide directed towards the C-terminal region of Human DFFB
PurificationAffinity Purified
Peptide SequenceSynthetic peptide located within the following region: LRSMQYNGSYFDRGAKGGSRLCTPEGWFSCQGPFDMDSCLSRHSINPYSN
Concentration0.5 mg/ml
Blocking PeptideFor anti-DFFB (ARP73821_P050) antibody is Catalog # AAP73821
Gene SymbolDFFB
Alias SymbolsCAD, CPAN, DFF2, DFF40, DFF-40
NCBI Gene Id1677
Description of TargetApoptosis is a cell death process that removes toxic and/or useless cells during mammalian development. The apoptotic process is accompanied by shrinkage and fragmentation of the cells and nuclei and degradation of the chromosomal DNA into nucleosomal units. DNA fragmentation factor (DFF) is a heterodimeric protein of 40-kD (DFFB) and 45-kD (DFFA) subunits. DFFA is the substrate for caspase-3 and triggers DNA fragmentation during apoptosis. DFF becomes activated when DFFA is cleaved by caspase-3. The cleaved fragments of DFFA dissociate from DFFB, the active component of DFF. DFFB has been found to trigger both DNA fragmentation and chromatin condensation during apoptosis. Alternatively spliced transcript variants encoding distinct isoforms have been found for this gene but the biological validity of some of these variants has not been determined.
Uniprot IDO76075
Protein Accession #NP_004393
Protein Size (# AA)338
Molecular Weight37kDa
Protein InteractionsDFFA; UBC; NUBP1; MARCKS; APP; CAND1; COPS5; CUL1; CUL2; CUL5; NEDD8; CIDEB; DFFB; TOP2A;
  1. What is the species homology for "DFFB Antibody - C-terminal region (ARP73821_P050)"?

    The tested species reactivity for this item is "Human". This antibody is predicted to have homology to "Human".

  2. How long will it take to receive "DFFB Antibody - C-terminal region (ARP73821_P050)"?

    This item is available "Domestic: within 1-2 days delivery | International: 1-2 days".

  3. What buffer format is "DFFB Antibody - C-terminal region (ARP73821_P050)" provided in?

    This item is provided in "Liquid. Purified antibody supplied in 1x PBS buffer with 0.09% (w/v) sodium azide and 2% sucrose.".
    Additional format options may be available. For more information please contact info@avivasysbio.com.

  4. What are other names for "DFFB Antibody - C-terminal region (ARP73821_P050)"?

    This target may also be called "CAD, CPAN, DFF2, DFF40, DFF-40" in publications.

  5. What is the shipping cost for "DFFB Antibody - C-terminal region (ARP73821_P050)"?

    The shipping cost for this item is $40 within the US. Please contact us for specific shipping prices for international orders.

  6. What is the guarantee for "DFFB Antibody - C-terminal region (ARP73821_P050)"?

    All Aviva products have been through rigorous validations and carry 100% satisfaction guarantee.

  7. Can I get bulk pricing for "DFFB Antibody - C-terminal region (ARP73821_P050)"?

    You can get bulk pricing for this item by going here.

  8. What is the molecular weight of the protein?

    The molecular weight reported by Uniprot for this item is "37kDa".
    Please note observed molecular weights in western blot applications may differ depending on a variety of protein characteristics.

  9. What protocols are available for "DFFB Antibody - C-terminal region (ARP73821_P050)"?

    We may have detailed protocol data avaialble for this item. To learn more, please view the "Protocols & Data" tab on the product page.

  10. What are positive controls for "DFFB"?

    We have listed RNA Seq and gene expression data in the "Target Info" tab. You may be able to find adequate positive controls there.

  11. What are negative controls for "DFFB"?

    We have listed RNA Seq and gene expression data in the "Target Info" tab. You may be able to find adequate positive controls there.

  12. What other proteins interact with "DFFB"?

    This protein has been reported to interact with "Protein Interactions". Please view the "Related Categories" tab on the product page for more information.

  13. What biological processes are associated with "DFFB"?

    This protein has been associated with "Biological Processes". Please view the "Related Categories" tab on the product page for more information.

  14. What cellular components are associated with "DFFB"?

    This protein has been associated with "Cellular Components". Please view the "Related Categories" tab on the product page for more information.

  15. What protein functions are associated with "DFFB"?

    This protein has been associated with "Protein Functions". Please view the "Related Categories" tab on the product page for more information.

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