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Now Offering Over 48,216 Antibodies & 21,887 Antigens!

Transcription Factor Antibodies

Transcription factors are proteins that regulate gene expression by binding to DNA via one or more DNA-binding domains. This binding is achieved via a combination of electrostatic and van der waals forces and can occur at many closely-related sequences flanking different genes. Once bound to DNA directly or as part of a complex, they can promote or inhibit RNA polymerase recruitment, thereby acting as activators or repressors, respectively. Alternatively, transcription factors can act to recruit coactivators and corepressors or to catalyze histone acetylation and deacetylation. Transcription factors can function downstream of signaling cascades triggered by biological or environmental (ex. hypoxia, hyperthermia) stimuli to alter the expression of target genes. Ligand binding is necessary to activate some transcription factors as this can cause nuclear translocation and changes in the binding affinities for DNA and cofactors. During development, various stimuli can cause transcription factors to up- or down-regulate expression of specific genes at distinct time points to ensure proper development. Transcription factors can function as oncogenes or tumor suppressors and have thus been linked to various cancers. Accordingly, some therapeutic approaches in cancer therapy involve targeting transcription factor families[1].

1. Darnell JE Jr. 2002. Transcription factors as targets for cancer therapy. Nat Rev Cancer. Oct;2(10):740-9.

Transcription Factor Antibodies Top 20 Showcase

View the entire product list by clicking here.

Transcription Factors are involved in transcriptional regulation in the form of up regulation or down regulation acting as either repressors or activators of transcription. We have manufactured more than 3000 antibody products covering almost every known human and mouse transcription factors.

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Showing 181 - 210 of 3652
  Type Catalog # Product Product Images Price (USD)
  pAb ARP31476_P050 CDX2 antibody - middle region (ARP31476_P050)
Reacts with
Chicken, Dog, Human, Mouse, Pig, Rabbit, Rat
Application
WB
$289.00
  pAb ARP31477_P050 SLC30A9 antibody - N-terminal region (ARP31477_P050)
Reacts with
Bovine, Dog, Guinea pig, Horse, Pig, Rabbit, Rat, Chicken, Mouse
Application
WB, IHC
$289.00
  pAb ARP31478_P050 CDX4 antibody - middle region (ARP31478_P050)
Reacts with
Dog, Human, Bovine, Chicken, Mouse, Rat, Zebrafish, African clawed frog
Application
WB, IHC
$289.00
  pAb ARP31479_P050 TADA3L antibody - middle region (ARP31479_P050)
Reacts with
Zebrafish
Application
WB
$289.00
  pAb ARP31488_P050 DRAP1 antibody - N-terminal region (ARP31488_P050)
Reacts with
Goat, Guinea pig, Human, Mouse, Rabbit, Zebrafish
Application
WB
$289.00
  pAb ARP31493_P050 KLF1 antibody - middle region (ARP31493_P050)
Reacts with
Human, Bovine, Mouse, Dog, Pig, Rat
Application
WB
$289.00
  pAb ARP31497_P050 TBR1 antibody - middle region (ARP31497_P050)
Reacts with
Bovine, Dog, Human, Pig, Mouse, Rat
Application
WB
$289.00
  pAb ARP31500_P050 TCFL5 antibody - middle region (ARP31500_P050)
Reacts with
Human, Mouse, Bovine, Dog, Guinea pig, Horse
Application
WB, IHC
$289.00
  pAb ARP31504_T100 ZNF274 antibody - N-terminal region (ARP31504_T100)
Reacts with
Rabbit, Dog, Pig
Application
WB, IHC
$229.00
  pAb ARP31507_P050 PPARGC1A antibody - N-terminal region (ARP31507_P050)
Reacts with
Chicken, Human, Rat, Bovine, Dog, Goat, Horse, Mouse, Pig, Rabbit
Application
WB
$289.00
  pAb ARP31512_P050 COPS5 antibody - N-terminal region (ARP31512_P050)
Reacts with
Dog, Horse, Human, Mouse, Pig, Rat, Bovine, Chicken
Application
WB
$289.00
  pAb ARP31513_T100 RIPK3 antibody - N-terminal region (ARP31513_T100)
Reacts with
Human, Dog, Horse, Mouse, Pig, Bovine
Application
WB, IHC
$229.00
  pAb ARP31514_T100 SALF antibody - C-terminal region (ARP31514_T100)
Reacts with
Western Gorilla, Human, Mouse, Crab-eating macaque, Bovine, Bornean orangutan, Pygmy chimpanzee, Western clawed frog, African clawed frog, Rat, Green puffer, White-throated sparrow, Body louse, Zebrafish
Application
WB
$229.00
  pAb ARP31516_P050 Prdm4 Antibody - C-terminal region (ARP31516_P050)
Reacts with
Application
WB
$289.00
  pAb ARP31518_P050 MYST2 antibody - N-terminal region (ARP31518_P050)
Reacts with
Horse, Mouse, Pig, Rat, African clawed frog, Chicken
Application
WB
$289.00
  pAb ARP31519_P050 SOX21 antibody - middle region (ARP31519_P050)
Reacts with
Bovine, Chicken, Human, Mouse, African clawed frog
Application
WB
$289.00
  pAb ARP31525_P050 TNRC4 antibody - N-terminal region (ARP31525_P050)
Reacts with
Bovine
Application
WB
$289.00
  pAb ARP31527_T100 PMF1 antibody - middle region (ARP31527_T100)
Reacts with
Human, Mouse, Pig, Rat, Guinea pig, Bovine, Dog
Application
WB
$229.00
  pAb ARP31533_P050 KLF8 antibody - N-terminal region (ARP31533_P050)
Reacts with
Human, Rabbit, Bovine
Application
WB, IHC
$289.00
  pAb ARP31534_P050 POU6F2 antibody - N-terminal region (ARP31534_P050)
Reacts with
Bovine, Chicken, Human, Mouse, Rabbit, Rat, Guinea pig
Application
WB
$289.00
  pAb ARP31539_P050 OSR2 antibody - N-terminal region (ARP31539_P050)
Reacts with
Human, African clawed frog, Bovine, Dog, Guinea pig, Horse, Mouse, Pig, Rabbit, Rat, Chicken
Application
WB
$289.00
  pAb ARP31540_P050 FOXP4 antibody - middle region (ARP31540_P050)
Reacts with
Bovine, Dog, Guinea pig, Horse, Human, Rabbit, Mouse, Pig, Rat, Zebrafish
Application
WB
$289.00
  pAb ARP31541_P050 4930567H17Rik antibody - middle region (ARP31541_P050)
Reacts with
Mouse
Application
WB
$289.00
  pAb ARP31542_P050 ERCC8 antibody - C-terminal region (ARP31542_P050)
Reacts with
Human, Dog, Horse, Rabbit
Application
WB, IHC
$289.00
  pAb ARP31545_P050 AEBP2 antibody - C-terminal region (ARP31545_P050)
Reacts with
African clawed frog, Bovine, Chicken, Dog, Guinea pig, Horse, Human, Mouse, Pig, Rabbit, Rat, Zebrafish
Application
WB
$289.00
  pAb ARP31546_P050 JDP2 antibody - N-terminal region (ARP31546_P050)
Reacts with
Human, Bovine, Mouse, Rabbit, Rat, Dog, Chicken
Application
WB
$289.00
  pAb ARP31552_P050 ZBTB8 antibody - C-terminal region (ARP31552_P050)
Reacts with
Horse, Mouse, Rat, Rabbit
Application
WB
$289.00
  pAb ARP31555_P050 ZNF513 antibody - N-terminal region (ARP31555_P050)
Reacts with
Bovine, Horse, Human, Rabbit, Dog
Application
WB
$289.00
  pAb ARP31558_P050 POU5F2 antibody - N-terminal region (ARP31558_P050)
Reacts with
Human
Application
WB
$289.00
  pAb ARP31562_P050 CREBL1 antibody - middle region (ARP31562_P050)
Reacts with
Pig
Application
WB
$289.00

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Showing 181 - 210 of 3652