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Now Offering Over 85,203 Antibodies & 34,301 Antigens!

Transcription Factor Antibodies

Transcription factors are proteins that regulate gene expression by binding to DNA via one or more DNA-binding domains. This binding is achieved via a combination of electrostatic and van der waals forces and can occur at many closely-related sequences flanking different genes. Once bound to DNA directly or as part of a complex, they can promote or inhibit RNA polymerase recruitment, thereby acting as activators or repressors, respectively. Alternatively, transcription factors can act to recruit coactivators and corepressors or to catalyze histone acetylation and deacetylation. Transcription factors can function downstream of signaling cascades triggered by biological or environmental (ex. hypoxia, hyperthermia) stimuli to alter the expression of target genes. Ligand binding is necessary to activate some transcription factors as this can cause nuclear translocation and changes in the binding affinities for DNA and cofactors. During development, various stimuli can cause transcription factors to up- or down-regulate expression of specific genes at distinct time points to ensure proper development. Transcription factors can function as oncogenes or tumor suppressors and have thus been linked to various cancers. Accordingly, some therapeutic approaches in cancer therapy involve targeting transcription factor families[1].

1. Darnell JE Jr. 2002. Transcription factors as targets for cancer therapy. Nat Rev Cancer. Oct;2(10):740-9.

Transcription Factor Antibodies Top 20 Showcase

View the entire product list by clicking here.

Transcription Factors are involved in transcriptional regulation in the form of up regulation or down regulation acting as either repressors or activators of transcription. We have manufactured more than 3000 antibody products covering almost every known human and mouse transcription factors.

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Showing 151 - 180 of 4061
  Type Catalog # Product Product Images Price (USD)
  pAb ARP30176_P050 GRP78 Antibody - C-terminal region (ARP30176_P050)
Reacts with
Human
Application
WB
$289.00
  pAb ARP58167_P050 NRL Antibody - C-terminal region (ARP58167_P050)
Reacts with
Human, Guinea pig, Horse, Rabbit, Rat, Dog
Application
WB
$289.00
  pAb ARP31865_P050 NR6A1 Antibody - middle region (ARP31865_P050)
Reacts with
Human
Application
WB
$289.00
  pAb ARP35662_P050 ZNF35 Antibody - N-terminal region (ARP35662_P050)
Reacts with
Human
Application
WB
$289.00
  pAb ARP33532_P050 ZBTB25 Antibody - middle region (ARP33532_P050)
Reacts with
Human
Application
WB
$289.00
  pAb ARP56437_P050 MK11 Antibody - N-terminal region (ARP56437_P050)
Reacts with
Human
Application
WB
$289.00
  pAb ARP33701_P050 TOX Antibody - middle region (ARP33701_P050)
Reacts with
Human
Application
WB
$289.00
  pAb ARP39780_P050 TRIM6 Antibody - C-terminal region (ARP39780_P050)
Reacts with
Rabbit, Rat, Human, Pig, Dog, Horse, Mouse, Bovine, Guinea pig
Application
WB
$289.00
  pAb ARP47741_P050 ZSC22 Antibody - N-terminal region (ARP47741_P050)
Reacts with
Human
Application
WB
$289.00
  pAb ARP39951_P050 ZN461 Antibody - C-terminal region (ARP39951_P050)
Reacts with
Human
Application
WB
$289.00
  pAb ARP34623_P050 TRIM8 Antibody - middle region (ARP34623_P050)
Reacts with
Human
Application
WB
$289.00
  pAb ARP39055_P050 SMARCAL1 Antibody - N-terminal region (ARP39055_P050)
Reacts with
Human
Application
WB
$289.00
  pAb ARP50431_P050 ZN284 Antibody - C-terminal region (ARP50431_P050)
Reacts with
Human
Application
WB
$289.00
  pAb ARP38434_T100 TRIP13 antibody - C-terminal region (ARP38434_T100)
Reacts with
Dog, Horse, Human, Rabbit, Bovine, Rat, Mouse, Pig, Guinea pig
Application
IHC, WB
$229.00
  pAb ARP45605_P050 NR4A1 Antibody - C-terminal region (ARP45605_P050)
Reacts with
Human, Horse, Guinea pig, Dog, Bovine, Rabbit, Mouse, Rat, Zebrafish
Application
WB
$289.00
  pAb ARP72430_P050 PTRF Antibody - C-terminal region (ARP72430_P050)
Reacts with
Human
Application
WB
$289.00
  pAb ARP35724_T100 TRIP13 antibody - N-terminal region (ARP35724_T100)
Reacts with
Bovine, Horse, Rabbit, Guinea pig, Human, Rat, Mouse, Dog
Application
IHC, WB
$229.00
  pAb ARP33721_T100 MORF4L2 antibody - N-terminal region (ARP33721_T100)
Reacts with
Mouse, Human, Dog, Pig, Horse, Rabbit, Rat, Bovine, Guinea pig
Application
IHC, WB
$229.00
  pAb ARP45604_P050 NR4A1 antibody - middle region (ARP45604_P050)
Reacts with
Human, Horse, Rabbit, Rat, Guinea pig, Dog, Mouse, Bovine
Application
IHC, WB
$289.00
  pAb ARP35782_P050 SSX4 antibody - N-terminal region (ARP35782_P050)
Reacts with
Human, Bovine
Application
WB
$289.00
  pAb ARP38433_P050 TRIP13 antibody - N-terminal region (ARP38433_P050)
Reacts with
Human, Pig, Dog, Bovine, Rabbit, Rat, Guinea pig, Mouse
Application
WB
$289.00
  pAb ARP35783_P050 SSX4 antibody - middle region (ARP35783_P050)
Reacts with
Human
Application
IHC, WB
$289.00
  pAb ARP33059_P050 SLC38A2 antibody - N-terminal region (ARP33059_P050)
Reacts with
Pig, Human, Bovine, Dog, Horse, Rabbit, Rat, Guinea pig, Mouse
Application
WB
$289.00
  pAb ARP30036_T100 GLIS2 antibody - N-terminal region (ARP30036_T100)
Reacts with
Human, Dog, Rat, Guinea pig, Rabbit, Mouse, Horse
Application
WB
$229.00
  pAb ARP34415_T100 PCGF3 antibody - middle region (ARP34415_T100)
Reacts with
Human, Dog, Rat, Bovine, Pig, Mouse, Rabbit, Horse, Guinea pig, Yeast
Application
WB
$229.00
  pAb ARP36965_T100 PTRF antibody - middle region (ARP36965_T100)
Reacts with
Mouse, Horse, Rat, Dog, Human, Bovine, Rabbit
Application
IHC, WB
$229.00
  pAb ARP38356_T100 HMGA2 antibody - N-terminal region (ARP38356_T100)
Reacts with
Human, Pig, Dog, Bovine, Zebrafish, Horse, Rabbit, Rat, Guinea pig, Mouse, Goat, Yeast
Application
WB
$229.00
  pAb ARP30037_P050 GLIS2 antibody - N-terminal region (ARP30037_P050)
Reacts with
Bovine, Dog, Horse, Rat, Guinea pig, Human, Zebrafish, Rabbit, Mouse
Application
IHC, WB
$289.00
  pAb ARP44074_P050 SLC8A3 antibody - N-terminal region (ARP44074_P050)
Reacts with
Human, Bovine, Mouse, Pig, Horse, Rabbit, Guinea pig, Rat, Dog
Application
WB
$289.00
  pAb ARP31941_T100 NR4A1 antibody - N-terminal region (ARP31941_T100)
Reacts with
Human, Horse, Dog, Bovine, Rabbit, Rat, Guinea pig, Mouse
Application
IHC, WB
$229.00

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Showing 151 - 180 of 4061