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Now Offering Over 85,203 Antibodies & 34,301 Antigens!

Transcription Factor Antibodies

Transcription factors are proteins that regulate gene expression by binding to DNA via one or more DNA-binding domains. This binding is achieved via a combination of electrostatic and van der waals forces and can occur at many closely-related sequences flanking different genes. Once bound to DNA directly or as part of a complex, they can promote or inhibit RNA polymerase recruitment, thereby acting as activators or repressors, respectively. Alternatively, transcription factors can act to recruit coactivators and corepressors or to catalyze histone acetylation and deacetylation. Transcription factors can function downstream of signaling cascades triggered by biological or environmental (ex. hypoxia, hyperthermia) stimuli to alter the expression of target genes. Ligand binding is necessary to activate some transcription factors as this can cause nuclear translocation and changes in the binding affinities for DNA and cofactors. During development, various stimuli can cause transcription factors to up- or down-regulate expression of specific genes at distinct time points to ensure proper development. Transcription factors can function as oncogenes or tumor suppressors and have thus been linked to various cancers. Accordingly, some therapeutic approaches in cancer therapy involve targeting transcription factor families[1].

1. Darnell JE Jr. 2002. Transcription factors as targets for cancer therapy. Nat Rev Cancer. Oct;2(10):740-9.

Transcription Factor Antibodies Top 20 Showcase

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Transcription Factors are involved in transcriptional regulation in the form of up regulation or down regulation acting as either repressors or activators of transcription. We have manufactured more than 3000 antibody products covering almost every known human and mouse transcription factors.

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Showing 151 - 180 of 3977
  Type Catalog # Product Product Images Price (USD)
  pAb ARP61185_P050 Zap70 antibody - middle region (ARP61185_P050)
Reacts with
Dog, Horse, Rabbit, Rat, Guinea pig, Human, Mouse, Bovine
Application
WB
$289.00
  pAb ARP38651_P050 SSX5 Antibody - C-terminal region (ARP38651_P050)
Reacts with
Human, Pig, Rat, Mouse, Rabbit
Application
WB
$289.00
  pAb ARP64530_P050 STXBP3 antibody - C-terminal region (ARP64530_P050)
Reacts with
Rabbit, Rat, Human, Mouse, Bovine, Dog, Horse, Pig, Zebrafish
Application
WB
$289.00
  pAb ARP50768_P050 ZNF678 Antibody - middle region (ARP50768_P050)
Reacts with
Human, Dog, Bovine, Mouse, Rat, Pig, Horse, Guinea pig, Rabbit
Application
WB
$289.00
  pAb ARP32526_P050 Zbtb38 antibody - C-terminal region (ARP32526_P050)
Reacts with
Zebrafish, Human, Pig, Rat, Bovine, Guinea pig, Mouse, Dog, Horse
Application
WB
$289.00
  pAb ARP51721_P050 SSX2 Antibody - middle region (ARP51721_P050)
Reacts with
Human
Application
WB
$289.00
  pAb ARP39847_P050 DHRSX antibody - N-terminal region (ARP39847_P050)
Reacts with
Bovine, Human, Rat, Yeast
Application
WB
$289.00
  pAb ARP30966_P050 Tcf3 Antibody - C-terminal region (ARP30966_P050)
Reacts with
Dog, Pig, Guinea pig, Human, Rat, Bovine, Mouse, Zebrafish, Horse, Rabbit
Application
WB
$289.00
  pAb ARP42659_P050 Nrbf2 antibody - N-terminal region (ARP42659_P050)
Reacts with
Mouse, Horse, Rabbit, Rat, Dog, Bovine, Human, Zebrafish
Application
WB
$289.00
  pAb ARP33537_P050 ZNF235 Antibody - N-terminal region (ARP33537_P050)
Reacts with
Human, Rat, Rabbit, Mouse, Guinea pig
Application
WB
$289.00
  pAb ARP32443_T100 LHX3 antibody - middle region (ARP32443_T100)
Reacts with
Human, Rat, Pig, Bovine, Zebrafish, Guinea pig, Mouse, Dog, Horse
Application
WB
$229.00
  pAb ARP63640_P050 CDC73 antibody - C-terminal region (ARP63640_P050)
Reacts with
Dog, Bovine, Rat, Horse, Rabbit, Human, Mouse, Zebrafish
Application
WB
$289.00
  pAb ARP37347_P050 Aste1 Antibody - C-terminal region (ARP37347_P050)
Reacts with
Mouse, Pig, Yeast, Rat
Application
WB
$289.00
  pAb ARP39952_P050 ZNF551 Antibody - N-terminal region (ARP39952_P050)
Reacts with
Bovine, Pig, Horse, Dog, Human, Rat, Rabbit, Guinea pig
Application
WB
$289.00
  pAb ARP58888_P050 STK17A Antibody - C-terminal region (ARP58888_P050)
Reacts with
Bovine, Human, Dog, Pig, Horse, Rabbit, Rat, Guinea pig
Application
WB
$289.00
  pAb ARP31097_P050 HSF2 antibody - N-terminal region (ARP31097_P050)
Reacts with
Bovine, Dog, Pig, Horse, Rabbit, Rat, Guinea pig, Human, Zebrafish, Mouse
Application
WB
$289.00
  pAb ARP30108_P050 Tsc22d4 Antibody - N-terminal region (ARP30108_P050)
Reacts with
Rat, Human, Dog, Rabbit, Guinea pig, Bovine, Mouse, Horse
Application
WB
$289.00
  pAb ARP72114_P050 SSX2B Antibody - middle region (ARP72114_P050)
Reacts with
Human
Application
WB
$289.00
  pAb ARP61198_P050 GET4 antibody - N-terminal region (ARP61198_P050)
Reacts with
Human, Mouse, Rat, Dog, Guinea pig, Horse, Bovine, Zebrafish
Application
WB
$289.00
  pAb ARP62578_P050 OBFC1 antibody - C-terminal region (ARP62578_P050)
Reacts with
Human, Horse, Dog, Pig, Mouse, Rat, Guinea pig, Bovine
Application
WB
$289.00
  pAb ARP33432_T100 TFAP2B antibody - C-terminal region (ARP33432_T100)
Reacts with
Human, Dog, Rat, Mouse, Horse, Rabbit, Guinea pig, Bovine, Zebrafish, Sheep
Application
WB
$229.00
  pAb ARP32044_P050 NKX2-2 Antibody - N-terminal region (ARP32044_P050)
Reacts with
Bovine, Dog, Horse, Rabbit, Pig, Human, Rat, Sheep, Mouse, Guinea pig
Application
WB
$289.00
  pAb ARP62985_P050 CD2 antibody - C-terminal region (ARP62985_P050)
Reacts with
Human, Pig, Dog, Horse, Bovine, Sheep, Rabbit
Application
WB
$289.00
  pAb ARP36809_P050 Dbx1 Antibody - C-terminal region (ARP36809_P050)
Reacts with
Mouse, Rat, Dog, Horse, Rabbit, Pig, Yeast, Human, Guinea pig, Bovine
Application
WB
$289.00
  pAb ARP62354_P050 Pitpnc1 antibody - middle region (ARP62354_P050)
Reacts with
Human, Pig, Rat, Dog, Horse, Rabbit, Guinea pig, Mouse, Zebrafish
Application
WB
$289.00
  pAb ARP39029_P050 ZNF284 Antibody - N-terminal region (ARP39029_P050)
Reacts with
Human, Bovine, Pig, Rabbit, Rat, Dog, Mouse, Horse
Application
WB
$289.00
  pAb ARP64778_P050 MMP28 antibody - C-terminal region (ARP64778_P050)
Reacts with
Human, Horse, Dog, Bovine
Application
WB
$289.00
  pAb ARP51028_P050 ZNF701 Antibody - middle region (ARP51028_P050)
Reacts with
Human, Mouse, Zebrafish, Bovine, Rat, Dog, Pig, Horse, Rabbit
Application
WB
$289.00
  pAb ARP35960_P050 MESP1 antibody - C-terminal region (ARP35960_P050)
Reacts with
Human, Bovine, Horse
Application
WB
$289.00
  pAb ARP33660_P050 ZNF92 Antibody - middle region (ARP33660_P050)
Reacts with
Human, Pig
Application
WB
$289.00

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Showing 151 - 180 of 3977