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Now Offering Over 85,203 Antibodies & 34,301 Antigens!

Transcription Factor Antibodies

Transcription factors are proteins that regulate gene expression by binding to DNA via one or more DNA-binding domains. This binding is achieved via a combination of electrostatic and van der waals forces and can occur at many closely-related sequences flanking different genes. Once bound to DNA directly or as part of a complex, they can promote or inhibit RNA polymerase recruitment, thereby acting as activators or repressors, respectively. Alternatively, transcription factors can act to recruit coactivators and corepressors or to catalyze histone acetylation and deacetylation. Transcription factors can function downstream of signaling cascades triggered by biological or environmental (ex. hypoxia, hyperthermia) stimuli to alter the expression of target genes. Ligand binding is necessary to activate some transcription factors as this can cause nuclear translocation and changes in the binding affinities for DNA and cofactors. During development, various stimuli can cause transcription factors to up- or down-regulate expression of specific genes at distinct time points to ensure proper development. Transcription factors can function as oncogenes or tumor suppressors and have thus been linked to various cancers. Accordingly, some therapeutic approaches in cancer therapy involve targeting transcription factor families[1].

1. Darnell JE Jr. 2002. Transcription factors as targets for cancer therapy. Nat Rev Cancer. Oct;2(10):740-9.

Transcription Factor Antibodies Top 20 Showcase

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Transcription Factors are involved in transcriptional regulation in the form of up regulation or down regulation acting as either repressors or activators of transcription. We have manufactured more than 3000 antibody products covering almost every known human and mouse transcription factors.

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Showing 151 - 180 of 3976
  Type Catalog # Product Product Images Price (USD)
  pAb ARP59775_P050 Opn1mw antibody - C-terminal region (ARP59775_P050)
Reacts with
Rat, Mouse, Human, Horse, Rabbit, Dog, Guinea pig, Goat, Bovine
Application
WB
$289.00
  pAb ARP38275_P050 TEAD4 Antibody - N-terminal region (ARP38275_P050)
Reacts with
Human, Pig, Rat, Mouse, Horse, Rabbit, Guinea pig
Application
WB
$289.00
  pAb ARP51718_P050 SSX2B Antibody - N-terminal region (ARP51718_P050)
Reacts with
Human, Pig, Mouse, Dog
Application
WB
$289.00
  pAb ARP64419_P050 KRT6A antibody - middle region (ARP64419_P050)
Reacts with
Human, Rat, Bovine, Pig, Horse, Rabbit, Mouse, Sheep, Dog
Application
WB
$289.00
  pAb ARP36411_P050 Dhx38 antibody - N-terminal region (ARP36411_P050)
Reacts with
Human, Rat, Dog, Bovine, Horse, Rabbit, Guinea pig, Mouse, Zebrafish
Application
WB
$289.00
  pAb ARP32853_P050 Zhx1 antibody - C-terminal region (ARP32853_P050)
Reacts with
Human, Bovine, Pig, Horse, Rabbit, Rat, Dog, Mouse
Application
WB
$289.00
  pAb ARP40402_P050 Oas1g antibody - N-terminal region (ARP40402_P050)
Reacts with
Horse, Human, Mouse, Bovine, Dog, Pig, Rat, Rabbit, Guinea pig
Application
WB
$289.00
  pAb ARP68610_P050 MACROD1 Antibody - N-terminal region (ARP68610_P050)
Reacts with
Pig, Horse, Rat, Guinea pig, Bovine, Mouse, Human, Dog
Application
WB
$289.00
  pAb ARP38427_P050 ZNF284 Antibody - N-terminal region (ARP38427_P050)
Reacts with
Bovine, Pig, Rat, Dog, Human, Mouse, Horse
Application
WB
$289.00
  pAb ARP42764_P050 LOC100504025 antibody - C-terminal region (ARP42764_P050)
Reacts with
Zebrafish, Pig, Horse, Rabbit, Human
Application
WB
$289.00
  pAb ARP33565_P050 ZNF655 Antibody - N-terminal region (ARP33565_P050)
Reacts with
Human, Horse, Rat, Dog, Guinea pig, Mouse
Application
WB
$289.00
  pAb ARP50344_P050 ZNF271 Antibody - middle region (ARP50344_P050)
Reacts with
Human, Bovine, Pig, Rat, Rabbit, Horse, Mouse, Dog, Guinea pig
Application
WB
$289.00
  pAb ARP32237_P050 ZNF280B antibody - N-terminal region (ARP32237_P050)
Reacts with
Human, Bovine, Pig, Rat, Rabbit, Goat, Dog
Application
WB
$289.00
  pAb ARP37358_P050 Ilf2 Antibody - N-terminal region (ARP37358_P050)
Reacts with
Rat, Human, Dog, Bovine, Horse, Rabbit, Guinea pig, Mouse, Zebrafish
Application
WB
$289.00
  pAb ARP69904_P050 ZBTB34 Antibody - C-terminal region (ARP69904_P050)
Reacts with
Horse, Pig, Human, Mouse, Dog, Bovine, Rat, Guinea pig, Rabbit
Application
WB
$289.00
  pAb ARP64048_P050 PRKAG3 antibody - N-terminal region (ARP64048_P050)
Reacts with
Human
Application
WB
$289.00
  pAb ARP31114_P050 NFE2L1 antibody - C-terminal region (ARP31114_P050)
Reacts with
Mouse, Bovine, Human, Rat, Dog, Rabbit
Application
WB
$289.00
  pAb ARP30565_T100 CYR61 Antibody - middle region (ARP30565_T100)
Reacts with
Pig, Human, Dog, Horse, Rabbit, Rat, Guinea pig, Mouse, Bovine, Zebrafish
Application
WB
$229.00
  pAb ARP32232_P050 SPIC antibody - C-terminal region (ARP32232_P050)
Reacts with
Pig, Rat, Dog, Horse, Rabbit, Human, Bovine, Mouse, Guinea pig, Zebrafish
Application
WB
$289.00
  pAb ARP31305_P050 Lmo1 Antibody - C-terminal region (ARP31305_P050)
Reacts with
Pig, Dog, Human, Horse, Rat, Guinea pig, Mouse, Rabbit, Bovine, Zebrafish
Application
WB
$289.00
  pAb ARP61366_P050 CYSLTR1 antibody - C-terminal region (ARP61366_P050)
Reacts with
Human, Bovine, Horse, Dog, Guinea pig, Rabbit
Application
WB
$289.00
  pAb ARP31872_P050 AKAP8L Antibody - C-terminal region (ARP31872_P050)
Reacts with
Dog, Bovine, Pig, Horse, Rabbit, Rat, Mouse, Human, Zebrafish, Guinea pig
Application
WB
$289.00
  pAb ARP39664_P050 MXD3 Antibody - C-terminal region (ARP39664_P050)
Reacts with
Bovine, Dog, Pig, Horse, Rabbit, Rat, Human, Mouse, Guinea pig, Zebrafish
Application
WB
$289.00
  pAb ARP40086_P050 RFX4 antibody - N-terminal region (ARP40086_P050)
Reacts with
Zebrafish, Human, Mouse, Dog, Horse, Rabbit, Rat, Guinea pig, Yeast
Application
WB
$289.00
  pAb ARP62628_P050 KANK2 antibody - C-terminal region (ARP62628_P050)
Reacts with
Human, Dog, Bovine, Horse, Rat, Pig, Guinea pig, Mouse, Rabbit
Application
WB
$289.00
  pAb ARP36221_P050 ZNF114 Antibody - C-terminal region (ARP36221_P050)
Reacts with
Human
Application
WB
$289.00
  pAb ARP61755_P050 Tbce antibody - N-terminal region (ARP61755_P050)
Reacts with
Human, Mouse, Pig, Rabbit, Guinea pig, Horse, Bovine, Rat, Dog, Zebrafish, Yeast
Application
WB
$289.00
  pAb ARP30713_T100 HTR1E Antibody - N-terminal region (ARP30713_T100)
Reacts with
Human, Pig, Bovine, Horse, Dog
Application
WB
$229.00
  pAb ARP64564_P050 DRP2 antibody - middle region (ARP64564_P050)
Reacts with
Human, Horse, Rabbit, Guinea pig, Bovine, Dog, Rat, Mouse
Application
WB
$289.00
  pAb ARP72087_P050 ZNF735 Antibody - middle region (ARP72087_P050)
Reacts with
Human
Application
WB
$289.00

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Showing 151 - 180 of 3976