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Now Offering Over 85,203 Antibodies & 34,301 Antigens!

Transcription Factor Antibodies

Transcription factors are proteins that regulate gene expression by binding to DNA via one or more DNA-binding domains. This binding is achieved via a combination of electrostatic and van der waals forces and can occur at many closely-related sequences flanking different genes. Once bound to DNA directly or as part of a complex, they can promote or inhibit RNA polymerase recruitment, thereby acting as activators or repressors, respectively. Alternatively, transcription factors can act to recruit coactivators and corepressors or to catalyze histone acetylation and deacetylation. Transcription factors can function downstream of signaling cascades triggered by biological or environmental (ex. hypoxia, hyperthermia) stimuli to alter the expression of target genes. Ligand binding is necessary to activate some transcription factors as this can cause nuclear translocation and changes in the binding affinities for DNA and cofactors. During development, various stimuli can cause transcription factors to up- or down-regulate expression of specific genes at distinct time points to ensure proper development. Transcription factors can function as oncogenes or tumor suppressors and have thus been linked to various cancers. Accordingly, some therapeutic approaches in cancer therapy involve targeting transcription factor families[1].

1. Darnell JE Jr. 2002. Transcription factors as targets for cancer therapy. Nat Rev Cancer. Oct;2(10):740-9.

Transcription Factor Antibodies Top 20 Showcase

View the entire product list by clicking here.

Transcription Factors are involved in transcriptional regulation in the form of up regulation or down regulation acting as either repressors or activators of transcription. We have manufactured more than 3000 antibody products covering almost every known human and mouse transcription factors.

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Showing 151 - 180 of 3998
  Type Catalog # Product Product Images Price (USD)
  pAb ARP40415_P050 SRGN antibody - N-terminal region (ARP40415_P050)
Reacts with
Human, Rat, Mouse, Rabbit
Application
WB
$289.00
  pAb ARP72751_P050 GCM2 Antibody - N-terminal region (ARP72751_P050)
Reacts with
Human, Bovine, Dog, Horse, Rabbit, Rat, Guinea pig, Zebrafish, Mouse
Application
WB
$289.00
  pAb ARP30932_P050 LYL1 Antibody - C-terminal region (ARP30932_P050)
Reacts with
Pig, Human
Application
WB
$289.00
  pAb ARP54337_P050 Igfbp5 antibody - middle region (ARP54337_P050)
Reacts with
Sheep, Human, Pig, Dog, Goat, Rabbit, Rat, Bovine, Mouse, Horse, Guinea pig
Application
WB
$289.00
  pAb ARP34734_P050 GREB1 Antibody - N-terminal region (ARP34734_P050)
Reacts with
Bovine, Dog, Horse, Rabbit, Human, Mouse, Pig, Zebrafish, Rat, Guinea pig
Application
WB
$289.00
  pAb ARP39224_P050 2700060E02Rik antibody - C-terminal region (ARP39224_P050)
Reacts with
Dog, Zebrafish, Pig, Horse, Rabbit, Rat, Guinea pig, Mouse, Bovine, Human, Yeast
Application
WB
$289.00
  pAb ARP37533_P050 Zfp445 Antibody - middle region (ARP37533_P050)
Reacts with
Mouse, Rat
Application
WB
$289.00
  pAb ARP39661_P050 TCF7 Antibody - N-terminal region (ARP39661_P050)
Reacts with
Mouse, Rat, Bovine, Dog, Guinea pig, Human, Zebrafish
Application
WB
$289.00
  pAb ARP59371_P050 RWDD3 antibody - middle region (ARP59371_P050)
Reacts with
Human, Rat, Guinea pig, Dog, Mouse
Application
WB
$289.00
  pAb ARP41526_P050 Xpnpep2 antibody - C-terminal region (ARP41526_P050)
Reacts with
Mouse, Human, Horse, Rat, Bovine, Guinea pig, Dog, Rabbit
Application
WB
$289.00
  pAb ARP39651_P050 Bhlhe41 antibody - N-terminal region (ARP39651_P050)
Reacts with
Human, Mouse, Bovine, Horse, Rat, Guinea pig, Dog
Application
WB
$289.00
  pAb ARP51718_P050 SSX2B Antibody - N-terminal region (ARP51718_P050)
Reacts with
Human, Pig, Mouse, Dog
Application
WB
$289.00
  pAb ARP33060_P050 Pou3f1 Antibody - C-terminal region (ARP33060_P050)
Reacts with
Bovine, Dog, Pig, Horse, Rabbit, Guinea pig, Rat, Mouse, Human, Zebrafish
Application
WB
$289.00
  pAb ARP41273_P050 Rhou antibody - N-terminal region (ARP41273_P050)
Reacts with
Mouse, Bovine, Rabbit, Dog, Human, Zebrafish, Pig, Horse, Rat
Application
WB
$289.00
  pAb ARP32426_P050 DACH2 Antibody - C-terminal region (ARP32426_P050)
Reacts with
Human, Horse, Rabbit, Mouse, Dog, Rat, Bovine
Application
WB
$289.00
  pAb ARP49192_P050 Mgat5b antibody - C-terminal region (ARP49192_P050)
Reacts with
Rat, Bovine, Dog, Pig, Horse, Mouse, Guinea pig, Human, Zebrafish
Application
WB
$289.00
  pAb ARP36967_P050 Rel Antibody - C-terminal region (ARP36967_P050)
Reacts with
Mouse
Application
WB
$289.00
  pAb ARP38529_P050 HDAC1 Antibody - N-terminal region (ARP38529_P050)
Reacts with
Mouse, Human, Rat, Dog, Pig, Bovine, Zebrafish, Horse, Rabbit, Guinea pig
Application
WB
$289.00
  pAb ARP63493_P050 Il15ra antibody - N-terminal region (ARP63493_P050)
Reacts with
Pig, Bovine, Human, Dog, Horse, Rabbit, Rat, Guinea pig, Mouse
Application
WB
$289.00
  pAb ARP34165_P050 RCVRN antibody - C-terminal region (ARP34165_P050)
Reacts with
Horse, Human, Bovine, Dog, Rat, Pig, Mouse, Rabbit, Guinea pig
Application
WB
$289.00
  pAb ARP50343_P050 ZNF134 Antibody - middle region (ARP50343_P050)
Reacts with
Human, Dog, Rabbit, Bovine, Rat, Mouse, Pig, Horse, Goat, Guinea pig
Application
WB
$289.00
  pAb ARP64835_P050 NADK antibody - C-terminal region (ARP64835_P050)
Reacts with
Mouse, Human, Dog, Bovine, Horse, Rat, Rabbit, Guinea pig, Zebrafish
Application
WB
$289.00
  pAb ARP61955_P050 HMGN3 antibody - middle region (ARP61955_P050)
Reacts with
Dog, Horse, Rabbit, Guinea pig, Rat, Human, Mouse, Bovine
Application
WB
$289.00
  pAb ARP69918_P050 ZNF506 Antibody - C-terminal region (ARP69918_P050)
Reacts with
Mouse, Human, Zebrafish, Horse, Pig, Rat, Dog, Bovine
Application
WB
$289.00
  pAb ARP45620_P050 NR5A1 antibody - middle region (ARP45620_P050)
Reacts with
Human, Rat, Dog, Horse, Guinea pig, Mouse, Bovine, Sheep
Application
WB
$289.00
  pAb ARP69904_P050 ZBTB34 Antibody - C-terminal region (ARP69904_P050)
Reacts with
Horse, Pig, Human, Mouse, Dog, Bovine, Rat, Guinea pig, Rabbit
Application
WB
$289.00
  pAb ARP65625_P050 YY2 Antibody - C-terminal region (ARP65625_P050)
Reacts with
Human
Application
WB
$289.00
  pAb ARP53022_P050 ALS2CR11 antibody - N-terminal region (ARP53022_P050)
Reacts with
Human
Application
WB
$289.00
  pAb ARP30565_T100 CYR61 Antibody - middle region (ARP30565_T100)
Reacts with
Pig, Human, Dog, Horse, Rabbit, Rat, Guinea pig, Mouse, Bovine, Zebrafish
Application
WB
$229.00
  pAb ARP31119_P050 PGR Antibody - N-terminal region (ARP31119_P050)
Reacts with
Human, Mouse, Rat, Pig, Yeast, Rabbit, Goat
Application
WB
$289.00

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Showing 151 - 180 of 3998