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Now Offering Over 85,203 Antibodies & 34,301 Antigens!

Transcription Factor Antibodies

Transcription factors are proteins that regulate gene expression by binding to DNA via one or more DNA-binding domains. This binding is achieved via a combination of electrostatic and van der waals forces and can occur at many closely-related sequences flanking different genes. Once bound to DNA directly or as part of a complex, they can promote or inhibit RNA polymerase recruitment, thereby acting as activators or repressors, respectively. Alternatively, transcription factors can act to recruit coactivators and corepressors or to catalyze histone acetylation and deacetylation. Transcription factors can function downstream of signaling cascades triggered by biological or environmental (ex. hypoxia, hyperthermia) stimuli to alter the expression of target genes. Ligand binding is necessary to activate some transcription factors as this can cause nuclear translocation and changes in the binding affinities for DNA and cofactors. During development, various stimuli can cause transcription factors to up- or down-regulate expression of specific genes at distinct time points to ensure proper development. Transcription factors can function as oncogenes or tumor suppressors and have thus been linked to various cancers. Accordingly, some therapeutic approaches in cancer therapy involve targeting transcription factor families[1].

1. Darnell JE Jr. 2002. Transcription factors as targets for cancer therapy. Nat Rev Cancer. Oct;2(10):740-9.

Transcription Factor Antibodies Top 20 Showcase

View the entire product list by clicking here.

Transcription Factors are involved in transcriptional regulation in the form of up regulation or down regulation acting as either repressors or activators of transcription. We have manufactured more than 3000 antibody products covering almost every known human and mouse transcription factors.

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Showing 151 - 180 of 4170
  Type Catalog # Product Product Images Price (USD)
  pAb ARP57911_P050 ZN157 Antibody - N-terminal region (ARP57911_P050)
Reacts with
Horse; Human; Pig; Rabbit; Rat
Application
WB
$289.00
  pAb ARP32086_P050 REST Antibody - N-terminal region (ARP32086_P050)
Reacts with
Cow; Dog; Guinea Pig; Horse; Human; Mouse; Rabbit; Rat; Zebrafish
Application
WB
$289.00
  pAb ARP34883_P050 DIDO1 Antibody - N-terminal region (ARP34883_P050)
Reacts with
Cow; Dog; Guinea Pig; Horse; Human; Mouse; Rabbit; Rat
Application
WB
$289.00
  pAb ARP50661_P050 ZN273 Antibody - C-terminal region (ARP50661_P050)
Reacts with
Human
Application
WB
$289.00
  pAb ARP33532_P050 ZBTB25 Antibody - middle region (ARP33532_P050)
Reacts with
Cow; Dog; Horse; Human; Mouse; Pig; Rat
Application
WB
$289.00
  pAb ARP42813_P050 FOXR2 Antibody - middle region (ARP42813_P050)
Reacts with
Human; Yeast
Application
WB
$289.00
  pAb ARP57958_P050 ZNF358 Antibody - N-terminal region (ARP57958_P050)
Reacts with
Guinea Pig; Human
Application
WB
$289.00
  pAb ARP35494_P050 KCIP2 Antibody - N-terminal region (ARP35494_P050)
Reacts with
Cow; Dog; Guinea Pig; Horse; Human; Mouse; Rabbit; Rat; Zebrafish
Application
WB
$289.00
  pAb ARP33515_P050 ZN182 Antibody - C-terminal (ARP33515_P050)
Reacts with
Human
Application
WB
$289.00
  pAb ARP33598_P050 ZBTB3 Antibody - N-terminal region (ARP33598_P050)
Reacts with
Cow; Dog; Guinea Pig; Horse; Human; Mouse; Rabbit; Rat
Application
WB
$289.00
  pAb ARP58089_P050 GCFC2 Antibody - N-terminal region (ARP58089_P050)
Reacts with
Dog; Guinea Pig; Human; Mouse; Rat
Application
WB
$289.00
  pAb ARP30176_P050 GRP78 Antibody - C-terminal region (ARP30176_P050)
Reacts with
Cow; Dog; Goat; Guinea Pig; Horse; Human; Mouse; Rabbit; Rat; Zebrafish
Application
WB
$289.00
  pAb ARP33003_P050 PSMD6 Antibody - N-terminal region (ARP33003_P050)
Reacts with
Cow; Dog; Guinea Pig; Horse; Human; Mouse; Rabbit; Rat; Zebrafish
Application
WB
$289.00
  pAb ARP57553_P050 GPBL1 Antibody - C-terminal (ARP57553_P050)
Reacts with
Mouse
Application
WB
$289.00
  pAb ARP50908_P050 Z324B Antibody - N-terminal region (ARP50908_P050)
Reacts with
Human
Application
WB
$289.00
  pAb ARP38557_P050 PA24B Antibody - C-terminal region (ARP38557_P050)
Reacts with
Cow; Dog; Guinea Pig; Horse; Human; Mouse; Rabbit; Rat
Application
WB
$289.00
  Kit AWBK32749 ZFP67 Western Blot kit (10 reactions)
Reacts with
Application
$549.00
  pAb ARP58167_P050 NRL Antibody - C-terminal region (ARP58167_P050)
Reacts with
Dog; Guinea Pig; Horse; Human; Rabbit; Rat
Application
WB
$289.00
  pAb ARP39652_P050 BHE41 Antibody - C-terminal region (ARP39652_P050)
Reacts with
Cow; Dog; Human; Pig
Application
WB
$289.00
  pAb ARP31736_P050 SOX1 Antibody - C-terminal region (ARP31736_P050)
Reacts with
Cow; Dog; Human; Mouse; Rabbit
Application
WB
$289.00
  pAb ARP73684_P050 ZN846 Antibody - N-terminal region (ARP73684_P050)
Reacts with
Human
Application
WB
$289.00
  pAb ARP33277_P050 IKZF5 Antibody - middle region (ARP33277_P050)
Reacts with
Cow; Dog; Guinea Pig; Horse; Human; Mouse; Rabbit; Rat
Application
WB
$289.00
  pAb ARP31971_P050 APEX1 Antibody - N-terminal region (ARP31971_P050)
Reacts with
Dog; Guinea Pig; Horse; Human; Mouse; Rabbit; Rat
Application
WB
$289.00
  pAb ARP34648_P050 BTBD6 Antibody - C-terminal region (ARP34648_P050)
Reacts with
Cow; Dog; Guinea Pig; Horse; Human; Mouse; Rabbit; Rat; Zebrafish
Application
WB
$289.00
  pAb ARP74384_P050 ANRA2 Antibody - N-terminal region (ARP74384_P050)
Reacts with
Human
Application
WB
$289.00
  pAb ARP36103_P050 ZN160 Antibody - C-terminal region (ARP36103_P050)
Reacts with
Cow; Dog; Guinea Pig; Horse; Human; Mouse; Rabbit; Rat
Application
WB
$289.00
  pAb ARP32046_P050 NKX61 Antibody - N-terminal region (ARP32046_P050)
Reacts with
Cow; Dog; Horse; Human; Mouse; Pig; Rabbit; Rat
Application
WB
$289.00
  pAb ARP34856_P050 TRI52 Antibody - N-terminal region (ARP34856_P050)
Reacts with
Cow; Human; Pig
Application
WB
$289.00
  pAb ARP75154_P050 TERF1 Antibody - C-terminal region (ARP75154_P050)
Reacts with
Human
Application
WB
$289.00
  pAb ARP74349_P050 WDHD1 Antibody - C-terminal region (ARP74349_P050)
Reacts with
Human
Application
WB
$289.00

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Showing 151 - 180 of 4170