website statistics
Account Login 

Now Offering Over 85,203 Antibodies & 34,301 Antigens!

Transcription Factor Antibodies

Transcription factors are proteins that regulate gene expression by binding to DNA via one or more DNA-binding domains. This binding is achieved via a combination of electrostatic and van der waals forces and can occur at many closely-related sequences flanking different genes. Once bound to DNA directly or as part of a complex, they can promote or inhibit RNA polymerase recruitment, thereby acting as activators or repressors, respectively. Alternatively, transcription factors can act to recruit coactivators and corepressors or to catalyze histone acetylation and deacetylation. Transcription factors can function downstream of signaling cascades triggered by biological or environmental (ex. hypoxia, hyperthermia) stimuli to alter the expression of target genes. Ligand binding is necessary to activate some transcription factors as this can cause nuclear translocation and changes in the binding affinities for DNA and cofactors. During development, various stimuli can cause transcription factors to up- or down-regulate expression of specific genes at distinct time points to ensure proper development. Transcription factors can function as oncogenes or tumor suppressors and have thus been linked to various cancers. Accordingly, some therapeutic approaches in cancer therapy involve targeting transcription factor families[1].

1. Darnell JE Jr. 2002. Transcription factors as targets for cancer therapy. Nat Rev Cancer. Oct;2(10):740-9.

Transcription Factor Antibodies Top 20 Showcase

View the entire product list by clicking here.

Transcription Factors are involved in transcriptional regulation in the form of up regulation or down regulation acting as either repressors or activators of transcription. We have manufactured more than 3000 antibody products covering almost every known human and mouse transcription factors.

Page of 138

Showing 151 - 180 of 4137
  Type Catalog # Product Product Images Price (USD)
  pAb ARP34856_P050 TRI52 Antibody - N-terminal region (ARP34856_P050)
Reacts with
Human
Application
WB
$289.00
  pAb ARP50661_P050 ZN273 Antibody - C-terminal region (ARP50661_P050)
Reacts with
Human
Application
WB
$289.00
  pAb ARP33551_P050 ZN205 Antibody - N-terminal region (ARP33551_P050)
Reacts with
Human
Application
WB
$289.00
  pAb ARP36818_P050 ALX3 Antibody - C-terminal region (ARP36818_P050)
Reacts with
Human
Application
WB
$289.00
  pAb ARP33701_P050 TOX Antibody - middle region (ARP33701_P050)
Reacts with
Human
Application
WB
$289.00
  pAb ARP38557_P050 PA24B Antibody - C-terminal region (ARP38557_P050)
Reacts with
Human
Application
WB
$289.00
  pAb ARP58093_P050 USF2 Antibody - N-terminal region (ARP58093_P050)
Reacts with
Human
Application
WB
$289.00
  pAb ARP35701_P050 LDB1 Antibody - C-terminal region (ARP35701_P050)
Reacts with
Human
Application
WB
$289.00
  pAb ARP50908_P050 Z324B Antibody - N-terminal region (ARP50908_P050)
Reacts with
Human
Application
WB
$289.00
  Kit AWBK32749 ZFP67 Western Blot kit (10 reactions)
Reacts with
Application
$549.00
  pAb ARP30176_P050 GRP78 Antibody - C-terminal region (ARP30176_P050)
Reacts with
Human
Application
WB
$289.00
  pAb ARP39652_P050 BHE41 Antibody - C-terminal region (ARP39652_P050)
Reacts with
Human
Application
WB
$289.00
  pAb ARP31736_P050 SOX1 Antibody - C-terminal region (ARP31736_P050)
Reacts with
Human
Application
WB
$289.00
  pAb ARP36082_P050 ZNF514 Antibody - middle region (ARP36082_P050)
Reacts with
Human
Application
WB
$289.00
  pAb ARP57931_P050 SNPC5 Antibody - C-terminal region (ARP57931_P050)
Reacts with
Human
Application
WB
$289.00
  pAb ARP32063_P050 PAX3 Antibody - C-terminal region (ARP32063_P050)
Reacts with
Human
Application
WB
$289.00
  pAb ARP34851_P050 ZN576 Antibody - middle region (ARP34851_P050)
Reacts with
Human
Application
WB
$289.00
  pAb ARP33471_P050 TULP2 Antibody - C-terminal region (ARP33471_P050)
Reacts with
Human
Application
WB
$289.00
  pAb ARP33532_P050 ZBTB25 Antibody - middle region (ARP33532_P050)
Reacts with
Human
Application
WB
$289.00
  pAb ARP43247_P050 IRF1 Antibody - middle region (ARP43247_P050)
Reacts with
Human, Bovine, Pig, Horse, Rat, Guinea pig, Dog, Rabbit, Mouse
Application
WB
$289.00
  pAb ARP58017_P050 HOXA7 Antibody - C-terminal region (ARP58017_P050)
Reacts with
Human, Horse, Dog, Pig, Sheep, Rabbit, Mouse
Application
WB
$289.00
  pAb ARP50734_P050 SCRT2 Antibody - N-terminal region (ARP50734_P050)
Reacts with
Human
Application
WB
$289.00
  pAb ARP33598_P050 ZBTB3 Antibody - N-terminal region (ARP33598_P050)
Reacts with
Human
Application
WB
$289.00
  pAb ARP35667_P050 ZNF74 Antibody - N-terminal region (ARP35667_P050)
Reacts with
Human
Application
WB
$289.00
  pAb ARP39491_P050 ZN410 Antibody - C-terminal region (ARP39491_P050)
Reacts with
Human
Application
WB
$289.00
  pAb ARP50829_P050 ZFP41 Antibody - N-terminal region (ARP50829_P050)
Reacts with
Human
Application
WB
$289.00
  pAb ARP47599_P050 ZN256 Antibody - N-terminal region (ARP47599_P050)
Reacts with
Human
Application
WB
$289.00
  pAb ARP58167_P050 NRL Antibody - C-terminal region (ARP58167_P050)
Reacts with
Human, Guinea pig, Horse, Rabbit, Rat, Dog
Application
WB
$289.00
  pAb ARP30075_P050 ZIC4 Antibody - C-terminal region (ARP30075_P050)
Reacts with
Human
Application
WB
$289.00
  pAb ARP32704_P050 MNT Antibody - C-terminal region (ARP32704_P050)
Reacts with
Human
Application
WB
$289.00

Page of 138

Showing 151 - 180 of 4137