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Now Offering Over 85,203 Antibodies & 34,301 Antigens!

Transcription Factor Antibodies

Transcription factors are proteins that regulate gene expression by binding to DNA via one or more DNA-binding domains. This binding is achieved via a combination of electrostatic and van der waals forces and can occur at many closely-related sequences flanking different genes. Once bound to DNA directly or as part of a complex, they can promote or inhibit RNA polymerase recruitment, thereby acting as activators or repressors, respectively. Alternatively, transcription factors can act to recruit coactivators and corepressors or to catalyze histone acetylation and deacetylation. Transcription factors can function downstream of signaling cascades triggered by biological or environmental (ex. hypoxia, hyperthermia) stimuli to alter the expression of target genes. Ligand binding is necessary to activate some transcription factors as this can cause nuclear translocation and changes in the binding affinities for DNA and cofactors. During development, various stimuli can cause transcription factors to up- or down-regulate expression of specific genes at distinct time points to ensure proper development. Transcription factors can function as oncogenes or tumor suppressors and have thus been linked to various cancers. Accordingly, some therapeutic approaches in cancer therapy involve targeting transcription factor families[1].

1. Darnell JE Jr. 2002. Transcription factors as targets for cancer therapy. Nat Rev Cancer. Oct;2(10):740-9.

Transcription Factor Antibodies Top 20 Showcase

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Transcription Factors are involved in transcriptional regulation in the form of up regulation or down regulation acting as either repressors or activators of transcription. We have manufactured more than 3000 antibody products covering almost every known human and mouse transcription factors.

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Showing 151 - 180 of 3998
  Type Catalog # Product Product Images Price (USD)
  pAb ARP36007_P050 Wiz Antibody - C-terminal region (ARP36007_P050)
Reacts with
Human, Bovine, Dog, Pig, Horse, Rat, Mouse, Rabbit
Application
WB
$289.00
  pAb ARP61144_P050 Prom1 antibody - N-terminal region (ARP61144_P050)
Reacts with
Human, Guinea pig, Zebrafish, Horse, Rat, Bovine, Dog, Mouse
Application
WB
$289.00
  pAb ARP47795_P050 Bsx Antibody - middle region (ARP47795_P050)
Reacts with
Bovine, Dog, Pig, Horse, Rabbit, Human, Rat, Guinea pig, Mouse
Application
WB
$289.00
  pAb ARP64517_P050 NCK1 antibody - N-terminal region (ARP64517_P050)
Reacts with
Human, Rat, Pig, Sheep, Dog, Zebrafish, Horse, Rabbit, Guinea pig, Bovine, Mouse
Application
WB
$289.00
  pAb ARP39586_P050 Neurog2 antibody - C-terminal region (ARP39586_P050)
Reacts with
Human, Bovine, Horse, Rabbit, Rat, Dog, Mouse
Application
WB
$289.00
  pAb ARP39531_P050 NR1I2 Antibody - N-terminal region (ARP39531_P050)
Reacts with
Human
Application
WB
$289.00
  pAb ARP47628_P050 Cux2 Antibody - N-terminal region (ARP47628_P050)
Reacts with
Dog, Rat, Bovine, Pig, Rabbit, Guinea pig, Human, Mouse
Application
WB
$289.00
  pAb ARP42311_P050 SMR3B antibody - middle region (ARP42311_P050)
Reacts with
Human, Yeast, Bovine
Application
WB
$289.00
  pAb ARP57974_P050 EYA3 Antibody - middle region (ARP57974_P050)
Reacts with
Human, Guinea pig, Sheep, Bovine, Horse, Rat, Rabbit, Mouse
Application
WB
$289.00
  pAb ARP33463_P050 TSG101 Antibody - N-terminal region (ARP33463_P050)
Reacts with
Bovine, Dog, Human, Goat, Rabbit, Rat, Pig, Guinea pig, Mouse, Horse, Zebrafish
Application
WB
$289.00
  pAb ARP57966_P050 E2f5 antibody - C-terminal region (ARP57966_P050)
Reacts with
Human, Mouse, Rat, Horse, Dog, Pig, Guinea pig, Bovine
Application
WB
$289.00
  pAb ARP70576_P050 INO80C Antibody - N-terminal region (ARP70576_P050)
Reacts with
Human, Mouse, Rabbit, Rat, Bovine, Dog, Pig, Horse, Guinea pig
Application
WB
$289.00
  pAb ARP37243_P050 Ptf1a Antibody - N-terminal region (ARP37243_P050)
Reacts with
Mouse, Bovine, Pig, Rat, Human, Horse, Dog
Application
WB
$289.00
  pAb ARP35825_P050 ZNF79 antibody - N-terminal region (ARP35825_P050)
Reacts with
Human
Application
WB
$289.00
  pAb ARP38337_P050 ZNF195 Antibody - N-terminal region (ARP38337_P050)
Reacts with
Human, Mouse, Rat, Horse, Rabbit, Dog
Application
WB
$289.00
  pAb ARP39063_P050 Hoxd9 Antibody - N-terminal region (ARP39063_P050)
Reacts with
Bovine, Pig, Guinea pig, Human, Rat, Horse, Mouse, Rabbit
Application
WB
$289.00
  pAb ARP61138_P050 ACSS2 antibody - C-terminal region (ARP61138_P050)
Reacts with
Mouse, Bovine, Rat, Human, Pig, Dog, Zebrafish, Horse, Rabbit, Guinea pig, Goat
Application
WB
$289.00
  pAb ARP31510_P050 MORF4L1 Antibody - C-terminal region (ARP31510_P050)
Reacts with
Mouse, Human, Bovine, Zebrafish, Dog, Pig, Horse, Rabbit, Rat, Guinea pig
Application
WB
$289.00
  pAb ARP30643_P050 Ywhag antibody - N-terminal region (ARP30643_P050)
Reacts with
Zebrafish, Bovine, Mouse, Human, Dog, Pig, Horse, Rabbit, Rat, Guinea pig
Application
WB
$289.00
  pAb ARP50361_P050 ZNF658B Antibody - middle region (ARP50361_P050)
Reacts with
Human, Horse, Pig, Rat, Zebrafish, Bovine, Guinea pig, Mouse, Rabbit, Yeast, Dog
Application
WB
$289.00
  pAb ARP31872_P050 AKAP8L Antibody - C-terminal region (ARP31872_P050)
Reacts with
Dog, Bovine, Pig, Horse, Rabbit, Rat, Mouse, Human, Zebrafish, Guinea pig
Application
WB
$289.00
  pAb ARP62969_P050 CAMK2G antibody - C-terminal region (ARP62969_P050)
Reacts with
Human, Dog, Horse, Pig, Bovine, Rat
Application
WB
$289.00
  pAb ARP62340_P050 Ip6k1 antibody - N-terminal region (ARP62340_P050)
Reacts with
Human, Pig, Horse, Rat, Guinea pig, Mouse, Bovine, Rabbit, Dog
Application
WB
$289.00
  pAb ARP73230_P050 ZFP64 Antibody - C-terminal region (ARP73230_P050)
Reacts with
Human, Rat, Guinea pig, Mouse, Dog
Application
WB
$289.00
  pAb ARP64775_P050 JMY antibody - N-terminal region (ARP64775_P050)
Reacts with
Rat, Human, Mouse, Guinea pig, Bovine
Application
WB
$289.00
  pAb ARP35489_P050 KCNIP2 antibody - C-terminal region (ARP35489_P050)
Reacts with
Pig, Human, Bovine, Rat, Mouse, Dog, Horse, Rabbit, Guinea pig
Application
WB
$289.00
  pAb ARP40842_P050 Hsd17b11 antibody - middle region (ARP40842_P050)
Reacts with
Dog, Horse, Rabbit, Rat, Pig, Bovine, Human, Mouse
Application
WB
$289.00
  pAb ARP39702_P050 IKZF3 Antibody - middle region (ARP39702_P050)
Reacts with
Human, Bovine, Rat, Dog, Pig, Horse, Rabbit, Guinea pig, Mouse, Yeast
Application
WB
$289.00
  pAb ARP45395_P050 Mfng antibody - middle region (ARP45395_P050)
Reacts with
Zebrafish, Mouse, Human, Dog, Pig, Horse, Rat, Guinea pig, Bovine, Rabbit
Application
WB
$289.00
  pAb ARP58043_P050 ZNF44 Antibody - N-terminal region (ARP58043_P050)
Reacts with
Human
Application
WB
$289.00

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Showing 151 - 180 of 3998