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Transcription Factor Antibodies

Transcription factors are proteins that regulate gene expression by binding to DNA via one or more DNA-binding domains. This binding is achieved via a combination of electrostatic and van der waals forces and can occur at many closely-related sequences flanking different genes. Once bound to DNA directly or as part of a complex, they can promote or inhibit RNA polymerase recruitment, thereby acting as activators or repressors, respectively. Alternatively, transcription factors can act to recruit coactivators and corepressors or to catalyze histone acetylation and deacetylation. Transcription factors can function downstream of signaling cascades triggered by biological or environmental (ex. hypoxia, hyperthermia) stimuli to alter the expression of target genes. Ligand binding is necessary to activate some transcription factors as this can cause nuclear translocation and changes in the binding affinities for DNA and cofactors. During development, various stimuli can cause transcription factors to up- or down-regulate expression of specific genes at distinct time points to ensure proper development. Transcription factors can function as oncogenes or tumor suppressors and have thus been linked to various cancers. Accordingly, some therapeutic approaches in cancer therapy involve targeting transcription factor families[1].

1. Darnell JE Jr. 2002. Transcription factors as targets for cancer therapy. Nat Rev Cancer. Oct;2(10):740-9.

Transcription Factor Antibodies Top 20 Showcase

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Transcription Factors are involved in transcriptional regulation in the form of up regulation or down regulation acting as either repressors or activators of transcription. We have manufactured more than 3000 antibody products covering almost every known human and mouse transcription factors.

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Showing 151 - 180 of 4181
  Type Catalog # Product Product Images Price (USD)
  pAb ARP34533_P050 TRIM58 Antibody - N-terminal region (ARP34533_P050)
Reacts with
Cow, Dog, Horse, Human, Mouse, Pig, Rabbit, Rat
Application
WB
$289.00
  pAb ARP47693_P050 SNX29 Antibody - N-terminal region (ARP47693_P050)
Reacts with
Cow, Dog, Guinea Pig, Horse, Human, Mouse, Rabbit, Rat
Application
WB
$289.00
  pAb ARP30575_P050 IL17F Antibody - N-terminal region (ARP30575_P050)
Reacts with
Human
Application
WB
$289.00
  pAb ARP33217_P050 PRD12 Antibody - C-terminal region (ARP33217_P050)
Reacts with
Cow, Dog, Guinea Pig, Human, Mouse, Pig, Rabbit, Rat
Application
WB
$289.00
  pAb ARP76431_P050 SIX6 Antibody - middle region (ARP76431_P050)
Reacts with
Human
Application
WB
$289.00
  pAb ARP74591_P050 ING2 Antibody - middle region (ARP74591_P050)
Reacts with
Human
Application
WB
$289.00
  pAb ARP34720_P050 USF1 Antibody - N-terminal region (ARP34720_P050)
Reacts with
Cow, Dog, Guinea Pig, Horse, Human, Mouse, Pig, Rabbit, Rat
Application
WB
$289.00
  pAb ARP39055_P050 SMARCAL1 Antibody - N-terminal region (ARP39055_P050)
Reacts with
Cow, Dog, Horse, Human, Rat
Application
WB
$289.00
  pAb ARP75048_P050 POU2AF1 Antibody - N-terminal region (ARP75048_P050)
Reacts with
Human
Application
WB
$289.00
  pAb ARP76649_P050 TFAP2C Antibody - N-terminal region (ARP76649_P050)
Reacts with
Human
Application
WB
$289.00
  pAb ARP57911_P050 ZNF157 Antibody - N-terminal region (ARP57911_P050)
Reacts with
Horse, Human, Pig, Rabbit, Rat
Application
WB
$289.00
  pAb ARP32086_P050 REST Antibody - N-terminal region (ARP32086_P050)
Reacts with
Cow, Dog, Guinea Pig, Horse, Human, Mouse, Rabbit, Rat, Zebrafish
Application
WB
$289.00
  pAb ARP74345_P050 VPS72 Antibody - N-terminal region (ARP74345_P050)
Reacts with
Human
Application
WB
$289.00
  pAb ARP33471_P050 TULP2 Antibody - C-terminal region (ARP33471_P050)
Reacts with
Human
Application
WB
$289.00
  pAb ARP36178_P050 ZSC29 Antibody - C-terminal region (ARP36178_P050)
Reacts with
Horse, Human, Pig
Application
WB
$289.00
  pAb ARP42813_P050 FOXR2 Antibody - middle region (ARP42813_P050)
Reacts with
Human, Yeast
Application
WB
$289.00
  pAb ARP77584_P050 ZNF286A Antibody - middle region (ARP77584_P050)
Reacts with
Human
Application
WB
$289.00
  pAb ARP57958_P050 ZNF358 Antibody - N-terminal region (ARP57958_P050)
Reacts with
Guinea Pig, Human
Application
WB
$289.00
  pAb ARP34883_P050 DIDO1 Antibody - N-terminal region (ARP34883_P050)
Reacts with
Cow, Dog, Guinea Pig, Horse, Human, Mouse, Rabbit, Rat
Application
WB
$289.00
  pAb ARP50661_P050 ZN273 Antibody - C-terminal region (ARP50661_P050)
Reacts with
Human
Application
WB
$289.00
  pAb ARP33532_P050 ZBTB25 Antibody - middle region (ARP33532_P050)
Reacts with
Cow, Dog, Horse, Human, Mouse, Pig, Rat
Application
WB
$289.00
  pAb ARP35494_P050 KCIP2 Antibody - N-terminal region (ARP35494_P050)
Reacts with
Cow, Dog, Guinea Pig, Horse, Human, Mouse, Rabbit, Rat, Zebrafish
Application
WB
$289.00
  pAb ARP33515_P050 ZNF182 Antibody - C-terminal (ARP33515_P050)
Reacts with
Human
Application
WB
$289.00
  pAb ARP33598_P050 ZBTB3 Antibody - N-terminal region (ARP33598_P050)
Reacts with
Cow, Dog, Guinea Pig, Horse, Human, Mouse, Rabbit, Rat
Application
WB
$289.00
  pAb ARP38557_P050 PA24B Antibody - C-terminal region (ARP38557_P050)
Reacts with
Cow, Dog, Guinea Pig, Horse, Human, Mouse, Rabbit, Rat
Application
WB
$289.00
  pAb ARP58089_P050 GCFC2 Antibody - N-terminal region (ARP58089_P050)
Reacts with
Dog, Guinea Pig, Human, Mouse, Rat
Application
WB
$289.00
  pAb ARP30176_P050 GRP78 Antibody - C-terminal region (ARP30176_P050)
Reacts with
Cow, Dog, Goat, Guinea Pig, Horse, Human, Mouse, Rabbit, Rat, Zebrafish
Application
WB, IHC
$289.00
  pAb ARP33003_P050 PSMD6 Antibody - N-terminal region (ARP33003_P050)
Reacts with
Cow, Dog, Guinea Pig, Horse, Human, Mouse, Rabbit, Rat, Zebrafish
Application
WB
$289.00
  pAb ARP57553_P050 Gpbp1l1 Antibody - C-terminal (ARP57553_P050)
Reacts with
Mouse
Application
WB
$289.00
  pAb ARP50908_P050 Z324B Antibody - N-terminal region (ARP50908_P050)
Reacts with
Human
Application
WB
$289.00

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Showing 151 - 180 of 4181