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Transcription Factor Antibodies

Transcription factors are proteins that regulate gene expression by binding to DNA via one or more DNA-binding domains. This binding is achieved via a combination of electrostatic and van der waals forces and can occur at many closely-related sequences flanking different genes. Once bound to DNA directly or as part of a complex, they can promote or inhibit RNA polymerase recruitment, thereby acting as activators or repressors, respectively. Alternatively, transcription factors can act to recruit coactivators and corepressors or to catalyze histone acetylation and deacetylation. Transcription factors can function downstream of signaling cascades triggered by biological or environmental (ex. hypoxia, hyperthermia) stimuli to alter the expression of target genes. Ligand binding is necessary to activate some transcription factors as this can cause nuclear translocation and changes in the binding affinities for DNA and cofactors. During development, various stimuli can cause transcription factors to up- or down-regulate expression of specific genes at distinct time points to ensure proper development. Transcription factors can function as oncogenes or tumor suppressors and have thus been linked to various cancers. Accordingly, some therapeutic approaches in cancer therapy involve targeting transcription factor families[1].

1. Darnell JE Jr. 2002. Transcription factors as targets for cancer therapy. Nat Rev Cancer. Oct;2(10):740-9.

Transcription Factor Antibodies Top 20 Showcase

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Transcription Factors are involved in transcriptional regulation in the form of up regulation or down regulation acting as either repressors or activators of transcription. We have manufactured more than 3000 antibody products covering almost every known human and mouse transcription factors.

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Showing 151 - 180 of 4022
  Type Catalog # Product Product Images Price (USD)
  pAb ARP37108_P050 Nfe2l2 Antibody - N-terminal region (ARP37108_P050)
Reacts with
Rat, Mouse, Rabbit, Bovine, Human, Yeast, Dog
Application
WB
$289.00
  pAb ARP63847_P050 SCG5 antibody - N-terminal region (ARP63847_P050)
Reacts with
Pig, Human, Dog, Horse, Rat, Guinea pig, Mouse, Bovine, Rabbit, Zebrafish
Application
WB
$289.00
  pAb ARP50344_P050 ZNF271 Antibody - middle region (ARP50344_P050)
Reacts with
Human, Bovine, Pig, Rat, Rabbit, Horse, Mouse, Dog, Guinea pig
Application
WB
$289.00
  pAb ARP57301_P050 Terf2ip antibody - middle region (ARP57301_P050)
Reacts with
Dog, Rabbit, Rat, Guinea pig, Human, Mouse, Horse, Bovine
Application
WB
$289.00
  pAb ARP66266_P050 RQCD1 Antibody - middle region (ARP66266_P050)
Reacts with
Bovine, Human, Dog, Pig, Horse, Rabbit, Rat, Guinea pig, Zebrafish, Mouse, Yeast, Goat
Application
WB
$289.00
  pAb ARP49709_P050 Popdc3 antibody - C-terminal region (ARP49709_P050)
Reacts with
Pig, Rabbit, Rat, Guinea pig, Dog, Human, Mouse, Horse, Zebrafish, Bovine
Application
WB
$289.00
  pAb ARP47520_P050 LOC685849 Antibody - N-terminal region (ARP47520_P050)
Reacts with
Human, Rat, Horse, Rabbit, Guinea pig, Mouse, Bovine
Application
WB
$289.00
  pAb ARP72146_P050 SOHLH2 Antibody - N-terminal region (ARP72146_P050)
Reacts with
Human, Guinea pig, Dog, Horse, Mouse
Application
WB
$289.00
  pAb ARP58238_P050 PHLDA2 antibody - N-terminal region (ARP58238_P050)
Reacts with
Human, Bovine, Rat, Pig, Horse, Guinea pig
Application
WB
$289.00
  pAb ARP31225_P050 RARB Antibody - N-terminal region (ARP31225_P050)
Reacts with
Bovine, Human, Dog, Horse, Rabbit, Guinea pig, Rat, Mouse
Application
WB
$289.00
  pAb ARP62355_P050 PROSC antibody - C-terminal region (ARP62355_P050)
Reacts with
Human, Rat, Guinea pig, Dog, Mouse
Application
WB
$289.00
  pAb ARP35248_P050 GRIK4 Antibody - C-terminal region (ARP35248_P050)
Reacts with
Human, Dog, Pig, Rabbit, Guinea pig, Rat, Mouse, Horse
Application
WB
$289.00
  pAb ARP56937_P050 Dnajc27 antibody - N-terminal region (ARP56937_P050)
Reacts with
Bovine, Human, Dog, Pig, Horse, Rabbit, Rat, Guinea pig, Mouse, Zebrafish
Application
WB
$289.00
  pAb ARP39935_P050 NPAS3 Antibody - middle region (ARP39935_P050)
Reacts with
Bovine, Pig, Mouse, Human, Rat, Zebrafish, Dog, Horse, Rabbit, Goat, Guinea pig
Application
WB
$289.00
  pAb ARP37877_P050 Runx1 Antibody - N-terminal region (ARP37877_P050)
Reacts with
Mouse, Rat, Pig, Human, Bovine, Dog, Rabbit, Guinea pig
Application
WB
$289.00
  pAb ARP64384_P050 ATG13 antibody - N-terminal region (ARP64384_P050)
Reacts with
Human, Dog, Pig, Horse, Rabbit, Rat, Guinea pig, Bovine, Mouse
Application
WB
$289.00
  pAb ARP35763_P050 Dlx6 antibody - C-terminal region (ARP35763_P050)
Reacts with
Rat, Dog, Bovine, Horse, Rabbit, Human, Guinea pig, Mouse, Zebrafish
Application
WB
$289.00
  pAb ARP30807_P050 CCR2 Antibody - N-terminal region (ARP30807_P050)
Reacts with
Human
Application
WB
$289.00
  pAb ARP36412_P050 DHX38 antibody - middle region (ARP36412_P050)
Reacts with
Human, Rat, Dog, Pig, Horse, Rabbit, Guinea pig, Mouse, Zebrafish, Bovine
Application
WB
$289.00
  pAb ARP30301_P050 NFKBIA Antibody - N-terminal region (ARP30301_P050)
Reacts with
Sheep, Dog, Pig, Rabbit, Human, Guinea pig, Rat, Bovine, Mouse
Application
WB
$289.00
  pAb ARP47361_P050 RGD1307830 antibody - C-terminal region (ARP47361_P050)
Reacts with
Rat, Horse, Rabbit, Mouse, Human, Dog, Bovine, Pig, Guinea pig
Application
WB
$289.00
  pAb ARP42311_P050 SMR3B antibody - middle region (ARP42311_P050)
Reacts with
Human, Yeast, Bovine
Application
WB
$289.00
  pAb ARP33423_P050 TWIST1 Antibody - N-terminal region (ARP33423_P050)
Reacts with
Horse, Bovine, Mouse, Human, Rat, Zebrafish
Application
WB
$289.00
  pAb ARP57966_P050 E2f5 antibody - C-terminal region (ARP57966_P050)
Reacts with
Human, Mouse, Rat, Horse, Dog, Pig, Guinea pig, Bovine
Application
WB
$289.00
  pAb ARP38975_P050 SCML4 Antibody - C-terminal region (ARP38975_P050)
Reacts with
Human, Dog, Zebrafish, Pig, Horse, Rabbit, Rat, Bovine, Guinea pig, Mouse
Application
WB
$289.00
  pAb ARP37179_P050 Irf5 Antibody - middle region (ARP37179_P050)
Reacts with
Mouse, Rat, Bovine, Dog, Pig, Horse, Rabbit, Guinea pig, Human
Application
WB
$289.00
  pAb ARP35825_P050 ZNF79 antibody - N-terminal region (ARP35825_P050)
Reacts with
Human
Application
WB
$289.00
  pAb ARP50658_P050 ZNF625 Antibody - middle region (ARP50658_P050)
Reacts with
Human, Horse
Application
WB
$289.00
  pAb ARP37945_P050 Naca-rs Antibody - C-terminal region (ARP37945_P050)
Reacts with
Mouse; Human
Application
WB
$289.00
  pAb ARP39063_P050 Hoxd9 Antibody - N-terminal region (ARP39063_P050)
Reacts with
Bovine, Pig, Guinea pig, Human, Rat, Horse, Mouse, Rabbit
Application
WB
$289.00

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Showing 151 - 180 of 4022