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Now Offering Over 85,203 Antibodies & 34,301 Antigens!

Transcription Factor Antibodies

Transcription factors are proteins that regulate gene expression by binding to DNA via one or more DNA-binding domains. This binding is achieved via a combination of electrostatic and van der waals forces and can occur at many closely-related sequences flanking different genes. Once bound to DNA directly or as part of a complex, they can promote or inhibit RNA polymerase recruitment, thereby acting as activators or repressors, respectively. Alternatively, transcription factors can act to recruit coactivators and corepressors or to catalyze histone acetylation and deacetylation. Transcription factors can function downstream of signaling cascades triggered by biological or environmental (ex. hypoxia, hyperthermia) stimuli to alter the expression of target genes. Ligand binding is necessary to activate some transcription factors as this can cause nuclear translocation and changes in the binding affinities for DNA and cofactors. During development, various stimuli can cause transcription factors to up- or down-regulate expression of specific genes at distinct time points to ensure proper development. Transcription factors can function as oncogenes or tumor suppressors and have thus been linked to various cancers. Accordingly, some therapeutic approaches in cancer therapy involve targeting transcription factor families[1].

1. Darnell JE Jr. 2002. Transcription factors as targets for cancer therapy. Nat Rev Cancer. Oct;2(10):740-9.

Transcription Factor Antibodies Top 20 Showcase

View the entire product list by clicking here.

Transcription Factors are involved in transcriptional regulation in the form of up regulation or down regulation acting as either repressors or activators of transcription. We have manufactured more than 3000 antibody products covering almost every known human and mouse transcription factors.

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Showing 151 - 180 of 4170
  Type Catalog # Product Product Images Price (USD)
  pAb ARP30575_P050 IL17F Antibody - N-terminal region (ARP30575_P050)
Reacts with
Human
Application
WB
$289.00
  pAb ARP38281_P050 TFAP2A Antibody - N-terminal region (ARP38281_P050)
Reacts with
Cow; Dog; Guinea Pig; Horse; Human; Mouse; Rabbit; Rat; Sheep; Zebrafish
Application
WB
$289.00
  pAb ARP33217_P050 PRD12 Antibody - C-terminal region (ARP33217_P050)
Reacts with
Cow; Dog; Guinea Pig; Human; Mouse; Pig; Rabbit; Rat
Application
WB
$289.00
  pAb ARP74932_P050 EVI1 Antibody - Middle region (ARP74932_P050)
Reacts with
Human
Application
WB
$289.00
  pAb ARP34533_P050 TRI58 Antibody - N-terminal region (ARP34533_P050)
Reacts with
Cow; Dog; Horse; Human; Mouse; Pig; Rabbit; Rat
Application
WB
$289.00
  pAb ARP10187_P050 ERBB2 Antibody - Middle region (ARP10187_P050)
Reacts with
Mouse
Application
WB
$289.00
  pAb ARP34720_P050 USF1 Antibody - N-terminal region (ARP34720_P050)
Reacts with
Cow; Dog; Guinea Pig; Horse; Human; Mouse; Pig; Rabbit; Rat
Application
WB
$289.00
  pAb ARP32086_P050 REST Antibody - N-terminal region (ARP32086_P050)
Reacts with
Cow; Dog; Guinea Pig; Horse; Human; Mouse; Rabbit; Rat; Zebrafish
Application
WB
$289.00
  pAb ARP75763_P050 CERS4 Antibody - C-terminal (ARP75763_P050)
Reacts with
Human
Application
WB
$289.00
  pAb ARP50909_P050 ZN662 Antibody - N-terminal region (ARP50909_P050)
Reacts with
Dog; Horse; Human
Application
WB
$289.00
  pAb ARP33471_P050 TULP2 Antibody - C-terminal region (ARP33471_P050)
Reacts with
Human
Application
WB
$289.00
  pAb ARP36178_P050 ZSC29 Antibody - C-terminal region (ARP36178_P050)
Reacts with
Horse; Human; Pig
Application
WB
$289.00
  pAb ARP58093_P050 USF2 Antibody - N-terminal region (ARP58093_P050)
Reacts with
Cow; Guinea Pig; Human; Mouse; Rabbit; Rat
Application
WB
$289.00
  pAb ARP37727_P050 ZN155 Antibody - C-terminal region (ARP37727_P050)
Reacts with
Human
Application
WB
$289.00
  pAb ARP34883_P050 DIDO1 Antibody - N-terminal region (ARP34883_P050)
Reacts with
Cow; Dog; Guinea Pig; Horse; Human; Mouse; Rabbit; Rat
Application
WB
$289.00
  pAb ARP33532_P050 ZBTB25 Antibody - middle region (ARP33532_P050)
Reacts with
Cow; Dog; Horse; Human; Mouse; Pig; Rat
Application
WB
$289.00
  pAb ARP35494_P050 KCIP2 Antibody - N-terminal region (ARP35494_P050)
Reacts with
Cow; Dog; Guinea Pig; Horse; Human; Mouse; Rabbit; Rat; Zebrafish
Application
WB
$289.00
  pAb ARP55311_P050 EPC2 Antibody - C-terminal region (ARP55311_P050)
Reacts with
Cow; Dog; Guinea Pig; Horse; Human; Mouse; Rabbit; Rat
Application
WB
$289.00
  pAb ARP74429_P050 CBX7 Antibody - C-terminal region (ARP74429_P050)
Reacts with
Human
Application
WB
$289.00
  pAb ARP33598_P050 ZBTB3 Antibody - N-terminal region (ARP33598_P050)
Reacts with
Cow; Dog; Guinea Pig; Horse; Human; Mouse; Rabbit; Rat
Application
WB
$289.00
  pAb ARP47741_P050 ZSC22 Antibody - N-terminal region (ARP47741_P050)
Reacts with
Dog; Human
Application
WB
$289.00
  Kit AWBK32749 ZFP67 Western Blot kit (10 reactions)
Reacts with
Application
$549.00
  pAb ARP30176_P050 GRP78 Antibody - C-terminal region (ARP30176_P050)
Reacts with
Cow; Dog; Goat; Guinea Pig; Horse; Human; Mouse; Rabbit; Rat; Zebrafish
Application
WB
$289.00
  pAb ARP33003_P050 PSMD6 Antibody - N-terminal region (ARP33003_P050)
Reacts with
Cow; Dog; Guinea Pig; Horse; Human; Mouse; Rabbit; Rat; Zebrafish
Application
WB
$289.00
  pAb ARP39134_P050 JADE3 Antibody - C-terminal region (ARP39134_P050)
Reacts with
Cow; Dog; Guinea Pig; Horse; Human; Mouse; Rabbit; Rat
Application
WB
$289.00
  pAb ARP76277_P050 HXD13 Antibody - N-terminal region (ARP76277_P050)
Reacts with
Human
Application
WB
$289.00
  pAb ARP50431_P050 ZN284 Antibody - C-terminal region (ARP50431_P050)
Reacts with
Human
Application
WB
$289.00
  pAb ARP41093_P050 LPPRC Antibody - N-terminal region (ARP41093_P050)
Reacts with
Cow; Dog; Guinea Pig; Horse; Human; Mouse; Rabbit; Rat; Zebrafish
Application
WB
$289.00
  pAb ARP57931_P050 SNPC5 Antibody - C-terminal region (ARP57931_P050)
Reacts with
Cow; Dog; Horse; Human; Pig
Application
WB
$289.00
  pAb ARP31736_P050 SOX1 Antibody - C-terminal region (ARP31736_P050)
Reacts with
Cow; Dog; Human; Mouse; Rabbit
Application
WB
$289.00

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Showing 151 - 180 of 4170