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Now Offering Over 85,203 Antibodies & 34,301 Antigens!

Transcription Factor Antibodies

Transcription factors are proteins that regulate gene expression by binding to DNA via one or more DNA-binding domains. This binding is achieved via a combination of electrostatic and van der waals forces and can occur at many closely-related sequences flanking different genes. Once bound to DNA directly or as part of a complex, they can promote or inhibit RNA polymerase recruitment, thereby acting as activators or repressors, respectively. Alternatively, transcription factors can act to recruit coactivators and corepressors or to catalyze histone acetylation and deacetylation. Transcription factors can function downstream of signaling cascades triggered by biological or environmental (ex. hypoxia, hyperthermia) stimuli to alter the expression of target genes. Ligand binding is necessary to activate some transcription factors as this can cause nuclear translocation and changes in the binding affinities for DNA and cofactors. During development, various stimuli can cause transcription factors to up- or down-regulate expression of specific genes at distinct time points to ensure proper development. Transcription factors can function as oncogenes or tumor suppressors and have thus been linked to various cancers. Accordingly, some therapeutic approaches in cancer therapy involve targeting transcription factor families[1].

1. Darnell JE Jr. 2002. Transcription factors as targets for cancer therapy. Nat Rev Cancer. Oct;2(10):740-9.

Transcription Factor Antibodies Top 20 Showcase

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Transcription Factors are involved in transcriptional regulation in the form of up regulation or down regulation acting as either repressors or activators of transcription. We have manufactured more than 3000 antibody products covering almost every known human and mouse transcription factors.

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Showing 151 - 180 of 3998
  Type Catalog # Product Product Images Price (USD)
  pAb ARP64805_P050 PACS1 antibody - C-terminal region (ARP64805_P050)
Reacts with
Human, Bovine, Dog, Rat, Pig, Horse, Guinea pig, Mouse, Zebrafish, Rabbit
Application
WB
$289.00
  pAb ARP34180_P050 Pax8 antibody - C-terminal region (ARP34180_P050)
Reacts with
Mouse, Rat, Bovine, Horse, Rabbit, Human, Pig, Dog, Guinea pig
Application
WB
$289.00
  pAb ARP66128_P050 AKNA Antibody - C-terminal region (ARP66128_P050)
Reacts with
Human, Rabbit, Rat
Application
WB
$289.00
  pAb ARP56087_P050 Pepd antibody - middle region (ARP56087_P050)
Reacts with
Mouse, Rat, Dog, Pig, Horse, Rabbit, Guinea pig, Human, Bovine, Zebrafish, Goat
Application
WB
$289.00
  pAb ARP71985_P050 WDR31 Antibody - middle region (ARP71985_P050)
Reacts with
Human, Guinea pig, Rat, Bovine, Mouse
Application
WB
$289.00
  pAb ARP30219_P050 SKP2 Antibody - C-terminal region (ARP30219_P050)
Reacts with
Bovine, Human, Pig, Rabbit, Dog, Horse, Guinea pig, Rat
Application
WB
$289.00
  pAb ARP50929_P050 LOC730644 antibody - middle region (ARP50929_P050)
Reacts with
Human
Application
WB
$289.00
  pAb ARP34179_P050 PAX8 Antibody - C-terminal region (ARP34179_P050)
Reacts with
Bovine, Horse, Pig, Dog, Human, Mouse, Rat, Guinea pig
Application
WB
$289.00
  pAb ARP49814_P050 Mfsd11 antibody - C-terminal region (ARP49814_P050)
Reacts with
Rat, Dog, Bovine, Horse, Guinea pig, Human, Mouse, Rabbit
Application
WB
$289.00
  pAb ARP37401_P050 Taf7l Antibody - C-terminal region (ARP37401_P050)
Reacts with
Mouse, Rat, Bovine, Pig
Application
WB
$289.00
  pAb ARP39395_P050 SLC2A4RG Antibody - C-terminal region (ARP39395_P050)
Reacts with
Human, Rat, Mouse
Application
WB
$289.00
  pAb ARP64147_P050 NTSR2 antibody - C-terminal region (ARP64147_P050)
Reacts with
Human, Yeast, Horse
Application
WB
$289.00
  pAb ARP33330_T100 SOX12 antibody - C-terminal region (ARP33330_T100)
Reacts with
Human, Rat, Dog, Horse, Pig, Mouse, Guinea pig
Application
WB
$229.00
  pAb ARP43698_P050 Dlg3 antibody - N-terminal region (ARP43698_P050)
Reacts with
Mouse, Bovine, Rabbit, Guinea pig, Human, Rat, Dog
Application
WB
$289.00
  pAb ARP57533_P050 Rprd1b Antibody - C-terminal region (ARP57533_P050)
Reacts with
Human, Bovine, Rat, Dog, Pig, Horse, Mouse, Rabbit, Guinea pig
Application
WB
$289.00
  pAb ARP35774_P050 NCOA4 antibody - C-terminal region (ARP35774_P050)
Reacts with
Human, Pig, Horse, Bovine, Dog, Rat
Application
WB
$289.00
  pAb ARP34597_P050 PRDM11 Antibody - C-terminal region (ARP34597_P050)
Reacts with
Human, Bovine, Dog, Pig, Mouse, Horse, Rabbit, Rat
Application
WB
$289.00
  pAb ARP64370_P050 ORAI3 Antibody - N-terminal region (ARP64370_P050)
Reacts with
Human, Bovine, Dog, Pig, Horse, Mouse, Rat, Guinea pig, Rabbit
Application
WB
$289.00
  pAb ARP32172_P050 Zfp580 antibody - middle region (ARP32172_P050)
Reacts with
Rat, Dog, Human, Mouse, Guinea pig
Application
WB
$289.00
  pAb ARP32044_P050 NKX2-2 Antibody - N-terminal region (ARP32044_P050)
Reacts with
Bovine, Dog, Horse, Rabbit, Pig, Human, Rat, Sheep, Mouse, Guinea pig
Application
WB
$289.00
  pAb ARP63610_P050 GHSR antibody - C-terminal region (ARP63610_P050)
Reacts with
Rabbit, Dog, Bovine, Goat, Horse, Guinea pig, Rat, Mouse, Sheep, Human
Application
WB
$289.00
  pAb ARP36265_P050 ZNF735 Antibody - middle region (ARP36265_P050)
Reacts with
Human
Application
WB
$289.00
  pAb ARP35727_P050 MED21 antibody - C-terminal region (ARP35727_P050)
Reacts with
Pig, Horse, Rat, Dog, Human, Bovine, Guinea pig, Mouse
Application
WB
$289.00
  pAb ARP38337_P050 ZNF195 Antibody - N-terminal region (ARP38337_P050)
Reacts with
Human, Mouse, Rat, Horse, Rabbit, Dog
Application
WB
$289.00
  pAb ARP63105_P050 Angpt1 antibody - C-terminal region (ARP63105_P050)
Reacts with
Human, Rat, Dog, Pig, Horse, Rabbit, Mouse, Bovine, Sheep, Guinea pig
Application
WB
$289.00
  pAb ARP33492_P050 SF1 antibody - N-terminal region (ARP33492_P050)
Reacts with
Bovine, Horse, Zebrafish, Rabbit, Human, Mouse, Dog, Rat, Pig, Guinea pig, Yeast, Goat
Application
WB
$289.00
  pAb ARP32384_T100 SIRT2 antibody - N-terminal region (ARP32384_T100)
Reacts with
Rabbit, Human, Pig, Bovine, Horse, Mouse, Guinea pig, Dog, Yeast, Rat
Application
WB
$229.00
  pAb ARP34855_P050 ZFP2 antibody - N-terminal region (ARP34855_P050)
Reacts with
Human, Guinea pig
Application
WB
$289.00
  pAb ARP68663_P050 KANSL2 Antibody - N-terminal region (ARP68663_P050)
Reacts with
Pig, Human, Rabbit, Dog, Horse, Rat, Guinea pig, Goat, Zebrafish, Mouse, Bovine
Application
WB
$289.00
  pAb ARP31546_P050 JDP2 antibody - N-terminal region (ARP31546_P050)
Reacts with
Horse, Human, Bovine, Rabbit, Guinea pig, Mouse, Rat, Dog
Application
WB
$289.00

Page of 134

Showing 151 - 180 of 3998