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Now Offering Over 85,203 Antibodies & 34,301 Antigens!

Transcription Factor Antibodies

Transcription factors are proteins that regulate gene expression by binding to DNA via one or more DNA-binding domains. This binding is achieved via a combination of electrostatic and van der waals forces and can occur at many closely-related sequences flanking different genes. Once bound to DNA directly or as part of a complex, they can promote or inhibit RNA polymerase recruitment, thereby acting as activators or repressors, respectively. Alternatively, transcription factors can act to recruit coactivators and corepressors or to catalyze histone acetylation and deacetylation. Transcription factors can function downstream of signaling cascades triggered by biological or environmental (ex. hypoxia, hyperthermia) stimuli to alter the expression of target genes. Ligand binding is necessary to activate some transcription factors as this can cause nuclear translocation and changes in the binding affinities for DNA and cofactors. During development, various stimuli can cause transcription factors to up- or down-regulate expression of specific genes at distinct time points to ensure proper development. Transcription factors can function as oncogenes or tumor suppressors and have thus been linked to various cancers. Accordingly, some therapeutic approaches in cancer therapy involve targeting transcription factor families[1].

1. Darnell JE Jr. 2002. Transcription factors as targets for cancer therapy. Nat Rev Cancer. Oct;2(10):740-9.

Transcription Factor Antibodies Top 20 Showcase

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Transcription Factors are involved in transcriptional regulation in the form of up regulation or down regulation acting as either repressors or activators of transcription. We have manufactured more than 3000 antibody products covering almost every known human and mouse transcription factors.

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Showing 151 - 180 of 4137
  Type Catalog # Product Product Images Price (USD)
  pAb ARP36178_P050 ZSC29 Antibody - C-terminal region (ARP36178_P050)
Reacts with
Human
Application
WB
$289.00
  pAb ARP56437_P050 MK11 Antibody - N-terminal region (ARP56437_P050)
Reacts with
Human
Application
WB
$289.00
  pAb ARP32156_P050 DMBX1 Antibody - middle region (ARP32156_P050)
Reacts with
Human
Application
WB
$289.00
  pAb ARP30991_P050 DMRT1 Antibody - middle region (ARP30991_P050)
Reacts with
Human, Bovine, Dog, Horse, Rabbit, Rat, Pig, Guinea pig, Mouse
Application
WB
$289.00
  pAb ARP40083_P050 TRI41 Antibody - N-terminal region (ARP40083_P050)
Reacts with
Human
Application
WB
$289.00
  pAb ARP35494_P050 KCIP2 Antibody - N-terminal region (ARP35494_P050)
Reacts with
Human
Application
WB
$289.00
  pAb ARP50506_P050 AIM2 Antibody - C-terminal region (ARP50506_P050)
Reacts with
Human
Application
WB
$289.00
  pAb ARP38063_P050 PAX6 Antibody - C-terminal region (ARP38063_P050)
Reacts with
Human
Application
WB
$289.00
  pAb ARP38281_P050 TFAP2A Antibody - N-terminal region (ARP38281_P050)
Reacts with
Human
Application
WB
$289.00
  pAb ARP31395_P050 ASCL1 Antibody - N-terminal region (ARP31395_P050)
Reacts with
Human
Application
WB
$289.00
  pAb ARP58045_P050 SETD4 Antibody - C-terminal region (ARP58045_P050)
Reacts with
Human
Application
WB
$289.00
  pAb ARP34316_P050 NCS1 Antibody - N-terminal region (ARP34316_P050)
Reacts with
Human
Application
WB
$289.00
  pAb ARP34623_P050 TRIM8 Antibody - middle region (ARP34623_P050)
Reacts with
Human
Application
WB
$289.00
  pAb ARP30573_P050 ID1 Antibody - middle region (ARP30573_P050)
Reacts with
Human
Application
WB
$289.00
  pAb ARP33217_P050 PRD12 Antibody - C-terminal region (ARP33217_P050)
Reacts with
Human
Application
WB
$289.00
  pAb ARP50909_P050 ZN662 Antibody - N-terminal region (ARP50909_P050)
Reacts with
Human
Application
WB
$289.00
  pAb ARP31865_P050 NR6A1 Antibody - middle region (ARP31865_P050)
Reacts with
Human
Application
WB
$289.00
  pAb ARP58372_P050 MFSD3 Antibody - N-terminal region (ARP58372_P050)
Reacts with
Human
Application
WB
$289.00
  pAb ARP36103_P050 ZN160 Antibody - C-terminal region (ARP36103_P050)
Reacts with
Human
Application
WB
$289.00
  pAb ARP55311_P050 EPC2 Antibody - C-terminal region (ARP55311_P050)
Reacts with
Human
Application
WB
$289.00
  pAb ARP32086_P050 REST Antibody - N-terminal region (ARP32086_P050)
Reacts with
Human
Application
WB
$289.00
  pAb ARP34854_P050 ZN614 Antibody - middle region (ARP34854_P050)
Reacts with
Human
Application
WB
$289.00
  pAb ARP47741_P050 ZSC22 Antibody - N-terminal region (ARP47741_P050)
Reacts with
Human
Application
WB
$289.00
  pAb ARP30945_P050 PAX5 Antibody - middle region (ARP30945_P050)
Reacts with
Human
Application
WB
$289.00
  pAb ARP33500_P050 ZFY Antibody - C-terminal region (ARP33500_P050)
Reacts with
Human
Application
WB
$289.00
  pAb ARP34971_P050 ACHB3 Antibody - N-terminal region (ARP34971_P050)
Reacts with
Human
Application
WB
$289.00
  pAb ARP39134_P050 JADE3 Antibody - C-terminal region (ARP39134_P050)
Reacts with
Human
Application
WB
$289.00
  pAb ARP50431_P050 ZN284 Antibody - C-terminal region (ARP50431_P050)
Reacts with
Human
Application
WB
$289.00
  pAb ARP31160_P050 AP2A Antibody - C-terminal region (ARP31160_P050)
Reacts with
Human
Application
WB
$289.00
  pAb ARP41093_P050 LPPRC Antibody - N-terminal region (ARP41093_P050)
Reacts with
Human
Application
WB
$289.00

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Showing 151 - 180 of 4137