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Now Offering Over 85,203 Antibodies & 34,301 Antigens!

Transcription Factor Antibodies

Transcription factors are proteins that regulate gene expression by binding to DNA via one or more DNA-binding domains. This binding is achieved via a combination of electrostatic and van der waals forces and can occur at many closely-related sequences flanking different genes. Once bound to DNA directly or as part of a complex, they can promote or inhibit RNA polymerase recruitment, thereby acting as activators or repressors, respectively. Alternatively, transcription factors can act to recruit coactivators and corepressors or to catalyze histone acetylation and deacetylation. Transcription factors can function downstream of signaling cascades triggered by biological or environmental (ex. hypoxia, hyperthermia) stimuli to alter the expression of target genes. Ligand binding is necessary to activate some transcription factors as this can cause nuclear translocation and changes in the binding affinities for DNA and cofactors. During development, various stimuli can cause transcription factors to up- or down-regulate expression of specific genes at distinct time points to ensure proper development. Transcription factors can function as oncogenes or tumor suppressors and have thus been linked to various cancers. Accordingly, some therapeutic approaches in cancer therapy involve targeting transcription factor families[1].

1. Darnell JE Jr. 2002. Transcription factors as targets for cancer therapy. Nat Rev Cancer. Oct;2(10):740-9.

Transcription Factor Antibodies Top 20 Showcase

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Transcription Factors are involved in transcriptional regulation in the form of up regulation or down regulation acting as either repressors or activators of transcription. We have manufactured more than 3000 antibody products covering almost every known human and mouse transcription factors.

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Showing 151 - 180 of 4153
  Type Catalog # Product Product Images Price (USD)
  pAb ARP58015_P050 HLX Antibody - C-terminal region (ARP58015_P050)
Reacts with
Human
Application
WB
$289.00
  pAb ARP34971_P050 ACHB3 Antibody - N-terminal region (ARP34971_P050)
Reacts with
Human
Application
WB
$289.00
  pAb ARP58059_P050 PSMD4 Antibody - C-terminal region (ARP58059_P050)
Reacts with
Human, Horse, Rabbit, Dog, Rat, Guinea pig, Sheep, Bovine, Mouse, Zebrafish
Application
WB
$289.00
  pAb ARP35667_P050 ZNF74 Antibody - N-terminal region (ARP35667_P050)
Reacts with
Human
Application
WB
$289.00
  pAb ARP39481_P050 ZNF8 Antibody - C-terminal region (ARP39481_P050)
Reacts with
Human
Application
WB
$289.00
  pAb ARP31395_P050 ASCL1 Antibody - N-terminal region (ARP31395_P050)
Reacts with
Human
Application
WB
$289.00
  pAb ARP35747_P050 CNOT8 Antibody - C-terminal region (ARP35747_P050)
Reacts with
Human
Application
WB
$289.00
  pAb ARP39559_P050 PRRX1 Antibody - N-terminal region (ARP39559_P050)
Reacts with
Human
Application
WB
$289.00
  pAb ARP31865_P050 NR6A1 Antibody - middle region (ARP31865_P050)
Reacts with
Human
Application
WB
$289.00
  pAb ARP47693_P050 SNX29 Antibody - N-terminal region (ARP47693_P050)
Reacts with
Human
Application
WB
$289.00
  pAb ARP30573_P050 ID1 Antibody - middle region (ARP30573_P050)
Reacts with
Human
Application
WB
$289.00
  pAb ARP34720_P050 USF1 Antibody - N-terminal region (ARP34720_P050)
Reacts with
Human
Application
WB
$289.00
  pAb ARP39055_P050 SMARCAL1 Antibody - N-terminal region (ARP39055_P050)
Reacts with
Human
Application
WB
$289.00
  pAb ARP75177_P050 ZNF32 Antibody - N-terminal region (ARP75177_P050)
Reacts with
Human
Application
WB
$289.00
  pAb ARP61523_P050 SSXT Antibody - C-terminal region (ARP61523_P050)
Reacts with
Human
Application
WB
$289.00
  pAb ARP33297_P050 SIM2 Antibody - middle region (ARP33297_P050)
Reacts with
Human
Application
WB
$289.00
  pAb ARP57912_P050 TRI26 Antibody - C-terminal region (ARP57912_P050)
Reacts with
Human
Application
WB
$289.00
  pAb ARP32063_P050 PAX3 Antibody - C-terminal region (ARP32063_P050)
Reacts with
Human
Application
WB
$289.00
  pAb ARP74420_P050 BRF2 Antibody - C-terminal region (ARP74420_P050)
Reacts with
Human
Application
WB
$289.00
  pAb ARP30945_P050 PAX5 Antibody - middle region (ARP30945_P050)
Reacts with
Human
Application
WB
$289.00
  pAb ARP36178_P050 ZSC29 Antibody - C-terminal region (ARP36178_P050)
Reacts with
Human
Application
WB
$289.00
  pAb ARP42813_P050 FOXR2 Antibody - middle region (ARP42813_P050)
Reacts with
Human
Application
WB
$289.00
  pAb ARP34883_P050 DIDO1 Antibody - N-terminal region (ARP34883_P050)
Reacts with
Human
Application
WB
$289.00
  pAb ARP50661_P050 ZN273 Antibody - C-terminal region (ARP50661_P050)
Reacts with
Human
Application
WB
$289.00
  pAb ARP31160_P050 AP2A Antibody - C-terminal region (ARP31160_P050)
Reacts with
Human
Application
WB
$289.00
  pAb ARP35494_P050 KCIP2 Antibody - N-terminal region (ARP35494_P050)
Reacts with
Human
Application
WB
$289.00
  pAb ARP33584_P050 SNIP1 Antibody - C-terminal region (ARP33584_P050)
Reacts with
Human
Application
WB
$289.00
  pAb ARP38557_P050 PA24B Antibody - C-terminal region (ARP38557_P050)
Reacts with
Human
Application
WB
$289.00
  pAb ARP58093_P050 USF2 Antibody - N-terminal region (ARP58093_P050)
Reacts with
Human
Application
WB
$289.00
  pAb ARP30091_P050 TF7L1 Antibody - C-terminal region (ARP30091_P050)
Reacts with
Human
Application
WB
$289.00

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Showing 151 - 180 of 4153