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Now Offering Over 85,203 Antibodies & 34,301 Antigens!

Transcription Factor Antibodies

Transcription factors are proteins that regulate gene expression by binding to DNA via one or more DNA-binding domains. This binding is achieved via a combination of electrostatic and van der waals forces and can occur at many closely-related sequences flanking different genes. Once bound to DNA directly or as part of a complex, they can promote or inhibit RNA polymerase recruitment, thereby acting as activators or repressors, respectively. Alternatively, transcription factors can act to recruit coactivators and corepressors or to catalyze histone acetylation and deacetylation. Transcription factors can function downstream of signaling cascades triggered by biological or environmental (ex. hypoxia, hyperthermia) stimuli to alter the expression of target genes. Ligand binding is necessary to activate some transcription factors as this can cause nuclear translocation and changes in the binding affinities for DNA and cofactors. During development, various stimuli can cause transcription factors to up- or down-regulate expression of specific genes at distinct time points to ensure proper development. Transcription factors can function as oncogenes or tumor suppressors and have thus been linked to various cancers. Accordingly, some therapeutic approaches in cancer therapy involve targeting transcription factor families[1].

1. Darnell JE Jr. 2002. Transcription factors as targets for cancer therapy. Nat Rev Cancer. Oct;2(10):740-9.

Transcription Factor Antibodies Top 20 Showcase

View the entire product list by clicking here.

Transcription Factors are involved in transcriptional regulation in the form of up regulation or down regulation acting as either repressors or activators of transcription. We have manufactured more than 3000 antibody products covering almost every known human and mouse transcription factors.

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Showing 151 - 180 of 4169
  Type Catalog # Product Product Images Price (USD)
  pAb ARP30991_P050 DMRT1 Antibody - middle region (ARP30991_P050)
Reacts with
Human, Bovine, Dog, Horse, Rabbit, Rat, Pig, Guinea pig, Mouse
Application
WB
$289.00
  pAb ARP33500_P050 ZFY Antibody - C-terminal region (ARP33500_P050)
Reacts with
Human
Application
WB
$289.00
  pAb ARP32119_P050 PAK6 Antibody - C-terminal region (ARP32119_P050)
Reacts with
Human
Application
WB
$289.00
  pAb ARP34851_P050 ZN576 Antibody - middle region (ARP34851_P050)
Reacts with
Human
Application
WB
$289.00
  pAb ARP39134_P050 JADE3 Antibody - C-terminal region (ARP39134_P050)
Reacts with
Human
Application
WB
$289.00
  pAb ARP74056_P050 MECP2 Antibody - N-terminal region (ARP74056_P050)
Reacts with
Human
Application
WB
$289.00
  pAb ARP41093_P050 LPPRC Antibody - N-terminal region (ARP41093_P050)
Reacts with
Human
Application
WB
$289.00
  pAb ARP57931_P050 SNPC5 Antibody - C-terminal region (ARP57931_P050)
Reacts with
Human
Application
WB
$289.00
  pAb ARP35662_P050 ZNF35 Antibody - N-terminal region (ARP35662_P050)
Reacts with
Human
Application
WB
$289.00
  pAb ARP39417_P050 SALL4 Antibody - N-terminal region (ARP39417_P050)
Reacts with
Human
Application
WB
$289.00
  pAb ARP74356_P050 ZHX3 Antibody - C-terminal region (ARP74356_P050)
Reacts with
Human
Application
WB
$289.00
  pAb ARP50764_P050 ZN418 Antibody - N-terminal region (ARP50764_P050)
Reacts with
Human
Application
WB
$289.00
  pAb ARP31395_P050 ASCL1 Antibody - N-terminal region (ARP31395_P050)
Reacts with
Human
Application
WB
$289.00
  pAb ARP58017_P050 HOXA7 Antibody - C-terminal region (ARP58017_P050)
Reacts with
Human, Horse, Dog, Pig, Sheep, Rabbit, Mouse
Application
WB
$289.00
  pAb ARP75587_P050 KLF13 Antibody - Middle region (ARP75587_P050)
Reacts with
Human
Application
WB
$289.00
  pAb ARP36818_P050 ALX3 Antibody - C-terminal region (ARP36818_P050)
Reacts with
Human
Application
WB
$289.00
  pAb ARP35927_P050 FEV Antibody - C-terminal region (ARP35927_P050)
Reacts with
Human
Application
WB
$289.00
  pAb ARP31865_P050 NR6A1 Antibody - middle region (ARP31865_P050)
Reacts with
Human
Application
WB
$289.00
  pAb ARP58133_P050 ASH2L Antibody - N-terminal region (ARP58133_P050)
Reacts with
Human
Application
WB
$289.00
  pAb ARP30573_P050 ID1 Antibody - middle region (ARP30573_P050)
Reacts with
Human
Application
WB
$289.00
  pAb ARP33297_P050 SIM2 Antibody - middle region (ARP33297_P050)
Reacts with
Human
Application
WB
$289.00
  pAb ARP37818_P050 ZSC29 Antibody - middle region (ARP37818_P050)
Reacts with
Human
Application
WB
$289.00
  pAb ARP39780_P050 TRIM6 Antibody - C-terminal region (ARP39780_P050)
Reacts with
Rabbit, Rat, Human, Pig, Dog, Horse, Mouse, Bovine, Guinea pig
Application
WB
$289.00
  pAb ARP53594_P050 CREM Antibody - middle region (ARP53594_P050)
Reacts with
Human
Application
WB
$289.00
  pAb ARP34659_P050 KLHL6 Antibody - N-terminal region (ARP34659_P050)
Reacts with
Human
Application
WB
$289.00
  pAb ARP47711_P050 BATF2 Antibody - N-terminal region (ARP47711_P050)
Reacts with
Human
Application
WB
$289.00
  pAb ARP75177_P050 ZNF32 Antibody - N-terminal region (ARP75177_P050)
Reacts with
Human
Application
WB
$289.00
  pAb ARP61523_P050 SSXT Antibody - C-terminal region (ARP61523_P050)
Reacts with
Human
Application
WB
$289.00
  pAb ARP30945_P050 PAX5 Antibody - middle region (ARP30945_P050)
Reacts with
Human
Application
WB
$289.00
  pAb ARP39951_P050 ZN461 Antibody - C-terminal region (ARP39951_P050)
Reacts with
Human
Application
WB
$289.00

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Showing 151 - 180 of 4169