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Now Offering Over 85,203 Antibodies & 34,301 Antigens!

Transcription Factor Antibodies

Transcription factors are proteins that regulate gene expression by binding to DNA via one or more DNA-binding domains. This binding is achieved via a combination of electrostatic and van der waals forces and can occur at many closely-related sequences flanking different genes. Once bound to DNA directly or as part of a complex, they can promote or inhibit RNA polymerase recruitment, thereby acting as activators or repressors, respectively. Alternatively, transcription factors can act to recruit coactivators and corepressors or to catalyze histone acetylation and deacetylation. Transcription factors can function downstream of signaling cascades triggered by biological or environmental (ex. hypoxia, hyperthermia) stimuli to alter the expression of target genes. Ligand binding is necessary to activate some transcription factors as this can cause nuclear translocation and changes in the binding affinities for DNA and cofactors. During development, various stimuli can cause transcription factors to up- or down-regulate expression of specific genes at distinct time points to ensure proper development. Transcription factors can function as oncogenes or tumor suppressors and have thus been linked to various cancers. Accordingly, some therapeutic approaches in cancer therapy involve targeting transcription factor families[1].

1. Darnell JE Jr. 2002. Transcription factors as targets for cancer therapy. Nat Rev Cancer. Oct;2(10):740-9.

Transcription Factor Antibodies Top 20 Showcase

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Transcription Factors are involved in transcriptional regulation in the form of up regulation or down regulation acting as either repressors or activators of transcription. We have manufactured more than 3000 antibody products covering almost every known human and mouse transcription factors.

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Showing 631 - 660 of 4159
  Type Catalog # Product Product Images Price (USD)
  pAb ARP30347_T100 AFP Antibody - C-terminal region (ARP30347_T100)
Reacts with
Cow, Dog, Horse, Human, Mouse, Pig, Rat
Application
WB
$229.00
  pAb ARP33022_P050 KDM3B Antibody - N-terminal region (ARP33022_P050)
Reacts with
Cow, Dog, Guinea Pig, Horse, Human, Mouse, Rabbit, Rat
Application
WB
$289.00
  pAb ARP32430_T100 BHLHB5 antibody - N-terminal region (ARP32430_T100)
Reacts with
Cow, Guinea Pig, Human, Mouse, Rabbit, Rat, Zebrafish
Application
WB
$229.00
  pAb ARP49814_P050 Mfsd11 antibody - C-terminal region (ARP49814_P050)
Reacts with
Cow, Dog, Guinea Pig, Horse, Human, Mouse, Rabbit, Rat
Application
WB
$289.00
  pAb ARP37533_P050 Zfp445 Antibody - middle region (ARP37533_P050)
Reacts with
Mouse, Rat
Application
WB
$289.00
  pAb ARP64147_P050 NTSR2 antibody - C-terminal region (ARP64147_P050)
Reacts with
Horse, Human, Yeast
Application
WB
$289.00
  pAb ARP33330_T100 SOX12 antibody - C-terminal region (ARP33330_T100)
Reacts with
Dog, Guinea Pig, Horse, Human, Mouse, Pig, Rat
Application
WB
$229.00
  pAb ARP43698_P050 Dlg3 antibody - N-terminal region (ARP43698_P050)
Reacts with
Cow, Dog, Guinea Pig, Human, Mouse, Rabbit, Rat
Application
WB
$289.00
  pAb ARP35774_P050 NCOA4 antibody - C-terminal region (ARP35774_P050)
Reacts with
Cow, Dog, Horse, Human, Pig, Rat
Application
WB
$289.00
  pAb ARP51024_P050 ZNF12 Antibody - N-terminal region (ARP51024_P050)
Reacts with
Cow, Horse, Human
Application
WB
$289.00
  pAb ARP64370_P050 ORAI3 Antibody - N-terminal region (ARP64370_P050)
Reacts with
Cow, Dog, Guinea Pig, Horse, Human, Mouse, Pig, Rabbit, Rat
Application
WB
$289.00
  pAb ARP32172_P050 Zfp580 antibody - middle region (ARP32172_P050)
Reacts with
Dog, Guinea Pig, Human, Mouse, Rat
Application
WB
$289.00
  pAb ARP60773_P050 SPANXB1 Antibody - middle region (ARP60773_P050)
Reacts with
Human
Application
WB
$289.00
  pAb ARP31591_P050 DDIT3 Antibody - N-terminal region (ARP31591_P050)
Reacts with
Cow, Dog, Goat, Guinea Pig, Horse, Human, Mouse, Rabbit, Rat, Sheep
Application
WB, IHC
$289.00
  pAb ARP38142_P050 Mxd1 antibody - C-terminal region (ARP38142_P050)
Reacts with
Cow, Dog, Guinea Pig, Horse, Human, Mouse, Rabbit, Rat
Application
WB
$289.00
  pAb ARP70065_P050 CSRNP2 Antibody - C-terminal region (ARP70065_P050)
Reacts with
Cow, Dog, Guinea Pig, Horse, Human, Rabbit, Rat, Sheep
Application
WB
$289.00
  pAb ARP31872_P050 AKAP8L Antibody - C-terminal region (ARP31872_P050)
Reacts with
Cow, Dog, Guinea Pig, Horse, Human, Mouse, Pig, Rabbit, Rat, Zebrafish
Application
WB
$289.00
  pAb ARP35727_P050 MED21 antibody - C-terminal region (ARP35727_P050)
Reacts with
Cow, Dog, Guinea Pig, Horse, Human, Mouse, Pig, Rat
Application
WB
$289.00
  pAb ARP72604_P050 NFE2L2 Antibody - C-terminal region (ARP72604_P050)
Reacts with
Cow, Dog, Guinea Pig, Horse, Human, Pig, Rabbit, Rat
Application
WB
$289.00
  pAb ARP63105_P050 Angpt1 antibody - C-terminal region (ARP63105_P050)
Reacts with
Cow, Dog, Guinea Pig, Horse, Human, Mouse, Pig, Rabbit, Rat, Sheep
Application
WB
$289.00
  pAb ARP32256_T100 NR2F6 antibody - N-terminal region (ARP32256_T100)
Reacts with
Cow, Dog, Guinea Pig, Human, Mouse, Rat
Application
WB
$229.00
  pAb ARP33492_P050 SF1 antibody - N-terminal region (ARP33492_P050)
Reacts with
Cow, Dog, Goat, Guinea Pig, Horse, Human, Mouse, Rabbit, Rat, Yeast, Zebrafish
Application
WB
$289.00
  pAb ARP38722_P050 TBX3 Antibody - C-terminal region (ARP38722_P050)
Reacts with
Cow, Dog, Guinea Pig, Human, Mouse, Pig, Rabbit, Rat, Zebrafish
Application
WB
$289.00
  pAb ARP32384_T100 SIRT2 antibody - N-terminal region (ARP32384_T100)
Reacts with
Cow, Dog, Guinea Pig, Horse, Human, Mouse, Pig, Rabbit, Rat, Yeast
Application
WB
$229.00
  pAb ARP34855_P050 ZFP2 antibody - N-terminal region (ARP34855_P050)
Reacts with
Guinea Pig, Human
Application
WB
$289.00
  pAb ARP32759_T100 HMG20A antibody - middle region (ARP32759_T100)
Reacts with
Cow, Dog, Guinea Pig, Horse, Human, Mouse, Rabbit, Rat
Application
WB
$229.00
  pAb ARP31546_P050 JDP2 antibody - N-terminal region (ARP31546_P050)
Reacts with
Cow, Dog, Guinea Pig, Horse, Human, Mouse, Rabbit, Rat
Application
WB
$289.00
  pAb ARP58193_P050 RORC Antibody - N-terminal region (ARP58193_P050)
Reacts with
Cow, Dog, Guinea Pig, Horse, Human, Mouse, Pig, Rabbit
Application
WB
$289.00
  pAb ARP51828_P050 C2orf76 antibody - N-terminal region (ARP51828_P050)
Reacts with
Cow, Dog, Guinea Pig, Horse, Human, Mouse, Rabbit, Rat
Application
WB
$289.00
  pAb ARP60556_P050 STK40 Antibody - N-terminal region (ARP60556_P050)
Reacts with
Cow, Dog, Guinea Pig, Horse, Human, Mouse, Rabbit, Rat
Application
WB
$289.00

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Showing 631 - 660 of 4159