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Now Offering Over 85,203 Antibodies & 34,301 Antigens!

Transcription Factor Antibodies

Transcription factors are proteins that regulate gene expression by binding to DNA via one or more DNA-binding domains. This binding is achieved via a combination of electrostatic and van der waals forces and can occur at many closely-related sequences flanking different genes. Once bound to DNA directly or as part of a complex, they can promote or inhibit RNA polymerase recruitment, thereby acting as activators or repressors, respectively. Alternatively, transcription factors can act to recruit coactivators and corepressors or to catalyze histone acetylation and deacetylation. Transcription factors can function downstream of signaling cascades triggered by biological or environmental (ex. hypoxia, hyperthermia) stimuli to alter the expression of target genes. Ligand binding is necessary to activate some transcription factors as this can cause nuclear translocation and changes in the binding affinities for DNA and cofactors. During development, various stimuli can cause transcription factors to up- or down-regulate expression of specific genes at distinct time points to ensure proper development. Transcription factors can function as oncogenes or tumor suppressors and have thus been linked to various cancers. Accordingly, some therapeutic approaches in cancer therapy involve targeting transcription factor families[1].

1. Darnell JE Jr. 2002. Transcription factors as targets for cancer therapy. Nat Rev Cancer. Oct;2(10):740-9.

Transcription Factor Antibodies Top 20 Showcase

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Transcription Factors are involved in transcriptional regulation in the form of up regulation or down regulation acting as either repressors or activators of transcription. We have manufactured more than 3000 antibody products covering almost every known human and mouse transcription factors.

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Showing 631 - 660 of 4153
  Type Catalog # Product Product Images Price (USD)
  pAb ARP39067_P050 Ubtf Antibody - N-terminal region (ARP39067_P050)
Reacts with
Mouse, Human, Dog, Bovine, Pig, Horse, Rabbit, Guinea pig, Rat
Application
WB
$289.00
  pAb ARP43147_P050 LOC683844 antibody - N-terminal region (ARP43147_P050)
Reacts with
Rat, Pig, Rabbit, Guinea pig, Bovine, Mouse, Human, Horse
Application
WB
$289.00
  pAb ARP51731_P050 HSFY2 Antibody - middle region (ARP51731_P050)
Reacts with
Human, Dog
Application
WB
$289.00
  pAb ARP32044_P050 NKX2-2 Antibody - N-terminal region (ARP32044_P050)
Reacts with
Bovine, Dog, Horse, Rabbit, Pig, Human, Rat, Sheep, Mouse, Guinea pig
Application
WB
$289.00
  pAb ARP51922_P050 ADPRH antibody - C-terminal region (ARP51922_P050)
Reacts with
Human, Dog, Pig, Horse, Bovine, Rat, Rabbit, Guinea pig, Mouse, Zebrafish
Application
WB
$289.00
  pAb ARP34784_P050 Rfx6 Antibody - middle region (ARP34784_P050)
Reacts with
Zebrafish, Human, Rat, Dog, Bovine, Pig, Horse, Rabbit, Guinea pig, Mouse
Application
WB
$289.00
  pAb ARP37194_P050 Uncx Antibody - N-terminal region (ARP37194_P050)
Reacts with
Bovine, Rat, Mouse, Human, Dog, Pig, Zebrafish
Application
WB
$289.00
  pAb ARP63674_P050 PGM2 antibody - C-terminal region (ARP63674_P050)
Reacts with
Human, Dog, Pig, Horse, Guinea pig, Mouse, Rabbit, Rat, Zebrafish, Bovine
Application
WB
$289.00
  pAb ARP39071_P050 RBPJL Antibody - N-terminal region (ARP39071_P050)
Reacts with
Human
Application
WB
$289.00
  pAb ARP63111_P050 DACT1 antibody - middle region (ARP63111_P050)
Reacts with
Mouse, Human, Rat, Bovine, Pig, Dog, Rabbit, Guinea pig, Zebrafish
Application
WB
$289.00
  pAb ARP50361_P050 ZNF658B Antibody - middle region (ARP50361_P050)
Reacts with
Human, Horse, Pig, Rat, Zebrafish, Bovine, Guinea pig, Mouse, Rabbit, Yeast, Dog
Application
WB
$289.00
  pAb ARP65976_P050 TBPL2 Antibody - N-terminal region (ARP65976_P050)
Reacts with
Human
Application
WB
$289.00
  pAb ARP49346_P050 PCDHA11 antibody - N-terminal region (ARP49346_P050)
Reacts with
Human, Mouse, Bovine, Horse, Rat, Rabbit, Pig, Guinea pig
Application
WB
$289.00
  pAb ARP61895_P050 Pkn2 Antibody - C-terminal region (ARP61895_P050)
Reacts with
Human, Zebrafish, Rat, Bovine, Dog, Pig, Horse, Rabbit, Mouse, Guinea pig, Yeast
Application
WB
$289.00
  pAb ARP30936_P050 MYB Antibody - C-terminal region (ARP30936_P050)
Reacts with
Human, Pig, Dog
Application
WB
$289.00
  pAb ARP55482_P050 SNX11 antibody - middle region (ARP55482_P050)
Reacts with
Mouse, Human, Rat, Dog, Pig, Horse, Rabbit, Guinea pig, Bovine, Yeast, Zebrafish
Application
WB
$289.00
  pAb ARP50946_P050 YBX1 Antibody - C-terminal region (ARP50946_P050)
Reacts with
Mouse, Rat, Pig, Rabbit, Dog, Human, Sheep, Guinea pig, Bovine, Horse
Application
WB
$289.00
  pAb ARP33388_P050 SUPT6H Antibody - N-terminal region (ARP33388_P050)
Reacts with
Human
Application
WB
$289.00
  pAb ARP56520_P050 Rdx antibody - C-terminal region (ARP56520_P050)
Reacts with
Bovine, Human, Dog, Rat, Pig, Horse, Rabbit, Guinea pig, Mouse, Zebrafish
Application
WB
$289.00
  pAb ARP37944_P050 Zhx2 Antibody - C-terminal region (ARP37944_P050)
Reacts with
Rat, Mouse
Application
WB
$289.00
  pAb ARP60034_P050 F2RL1 antibody - C-terminal region (ARP60034_P050)
Reacts with
Human, Dog, Rat, Guinea pig
Application
WB
$289.00
  pAb ARP43832_P050 Slc5a2 antibody - middle region (ARP43832_P050)
Reacts with
Human, Pig, Mouse, Dog, Rat, Horse, Rabbit, Guinea pig, Bovine
Application
WB
$289.00
  pAb ARP39952_P050 ZNF551 Antibody - N-terminal region (ARP39952_P050)
Reacts with
Bovine, Pig, Horse, Dog, Human, Rat, Rabbit, Guinea pig
Application
WB
$289.00
  pAb ARP35520_P050 Gm6185 antibody - middle region (ARP35520_P050)
Reacts with
Human, Rat, Horse, Rabbit, Guinea pig, Dog, Bovine
Application
WB
$289.00
  pAb ARP41046_P050 BRD9 Antibody - N-terminal region (ARP41046_P050)
Reacts with
Horse, Rabbit, Human, Dog, Rat, Bovine, Guinea pig, Mouse, Yeast, Zebrafish
Application
WB
$289.00
  pAb ARP36377_P050 DDX23 antibody - C-terminal region (ARP36377_P050)
Reacts with
Bovine, Human, Rat, Mouse, Dog, Horse, Rabbit, Guinea pig, Zebrafish, Yeast
Application
WB
$289.00
  pAb ARP67596_P050 KCTD1 Antibody - middle region (ARP67596_P050)
Reacts with
Mouse, Horse, Human, Dog, Pig, Goat, Rat, Guinea pig, Bovine, Rabbit
Application
WB
$289.00
  pAb ARP32256_P050 NR2F6 antibody - N-terminal region (ARP32256_P050)
Reacts with
Human, Dog, Bovine, Pig, Guinea pig, Rat, Mouse
Application
IHC, WB
$289.00
  pAb ARP46438_P050 COX6A1 antibody - N-terminal region (ARP46438_P050)
Reacts with
Human
Application
WB
$289.00
  pAb ARP34597_P050 PRDM11 Antibody - C-terminal region (ARP34597_P050)
Reacts with
Human, Bovine, Dog, Pig, Mouse, Horse, Rabbit, Rat
Application
WB
$289.00

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Showing 631 - 660 of 4153