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Now Offering Over 85,203 Antibodies & 34,301 Antigens!

Transcription Factor Antibodies

Transcription factors are proteins that regulate gene expression by binding to DNA via one or more DNA-binding domains. This binding is achieved via a combination of electrostatic and van der waals forces and can occur at many closely-related sequences flanking different genes. Once bound to DNA directly or as part of a complex, they can promote or inhibit RNA polymerase recruitment, thereby acting as activators or repressors, respectively. Alternatively, transcription factors can act to recruit coactivators and corepressors or to catalyze histone acetylation and deacetylation. Transcription factors can function downstream of signaling cascades triggered by biological or environmental (ex. hypoxia, hyperthermia) stimuli to alter the expression of target genes. Ligand binding is necessary to activate some transcription factors as this can cause nuclear translocation and changes in the binding affinities for DNA and cofactors. During development, various stimuli can cause transcription factors to up- or down-regulate expression of specific genes at distinct time points to ensure proper development. Transcription factors can function as oncogenes or tumor suppressors and have thus been linked to various cancers. Accordingly, some therapeutic approaches in cancer therapy involve targeting transcription factor families[1].

1. Darnell JE Jr. 2002. Transcription factors as targets for cancer therapy. Nat Rev Cancer. Oct;2(10):740-9.

Transcription Factor Antibodies Top 20 Showcase

View the entire product list by clicking here.

Transcription Factors are involved in transcriptional regulation in the form of up regulation or down regulation acting as either repressors or activators of transcription. We have manufactured more than 3000 antibody products covering almost every known human and mouse transcription factors.

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Showing 631 - 660 of 3946
  Type Catalog # Product Product Images Price (USD)
  pAb ARP32548_T100 GATA3 antibody - C-terminal region (ARP32548_T100)
Reacts with
Human, Dog, Pig, Horse, Sheep, Rabbit, Rat, Guinea pig, Mouse, Bovine
Application
IF, IHC, WB
$229.00
  pAb ARP32550_P050 GATA6 antibody - N-terminal region (ARP32550_P050)
Reacts with
Dog, Rat, Pig, Human, Mouse, Bovine
Application
IF, WB
$289.00
  pAb ARP32552_P050 GBX2 antibody - middle region (ARP32552_P050)
Reacts with
Rat, Pig, Rabbit, Guinea pig, Mouse, Human, Bovine, Dog, Horse
Application
WB
$289.00
  pAb ARP32553_T100 LHX6 antibody - C-terminal region (ARP32553_T100)
Reacts with
Rat, Dog, Human, Bovine, Mouse, Guinea pig
Application
IHC, WB
$229.00
  pAb ARP32554_P050 NR6A1 antibody - N-terminal region (ARP32554_P050)
Reacts with
Human, Rabbit, Rat, Mouse, Pig
Application
WB
$289.00
  pAb ARP32556_P050 NPAS4 antibody - middle region (ARP32556_P050)
Reacts with
Mouse, Dog, Pig, Rabbit, Rat, Human, Guinea pig, Bovine, Sheep, Horse
Application
WB
$289.00
  pAb ARP32557_P050 GFI1 antibody - N-terminal region (ARP32557_P050)
Reacts with
Human, Bovine, Pig, Rat, Horse, Guinea pig, Mouse, Dog, Rabbit
Application
WB
$289.00
  pAb ARP32560_P050 AKAP8L antibody - middle region (ARP32560_P050)
Reacts with
Human, Dog, Horse, Rabbit, Bovine, Pig, Mouse, Rat
Application
WB
$289.00
  pAb ARP32561_P050 FOXD3 antibody - middle region (ARP32561_P050)
Reacts with
Mouse, Bovine, Dog, Rat, Human
Application
WB
$289.00
  pAb ARP32563_T100 SND1 antibody - N-terminal region (ARP32563_T100)
Reacts with
Human, Zebrafish, Rat, Dog, Pig, Horse, Rabbit, Guinea pig, Mouse, Bovine
Application
WB
$229.00
  pAb ARP32564_T100 FOXP1 antibody - N-terminal region (ARP32564_T100)
Reacts with
Human, Mouse, Horse, Rabbit, Guinea pig, Rat, Bovine, Dog
Application
IHC, WB
$229.00
  pAb ARP32565_P050 TAF5L antibody - middle region (ARP32565_P050)
Reacts with
Rat, Dog, Bovine, Zebrafish, Pig, Horse, Rabbit, Guinea pig, Human, Mouse
Application
WB
$289.00
  pAb ARP32566_T100 TAF5L antibody - N-terminal region (ARP32566_T100)
Reacts with
Dog, Horse, Rabbit, Guinea pig, Human, Bovine, Rat, Mouse
Application
WB
$229.00
  pAb ARP32569_P050 ZNF777 antibody - middle region (ARP32569_P050)
Reacts with
Bovine, Mouse, Rat, Pig, Horse, Rabbit, Guinea pig, Human, Dog
Application
IHC, WB
$289.00
  pAb ARP32570_P050 SALL3 antibody - middle region (ARP32570_P050)
Reacts with
Human, Rat, Dog, Pig, Horse, Rabbit, Guinea pig, Mouse, Bovine, Zebrafish
Application
WB
$289.00
  pAb ARP32574_P050 MKX antibody - middle region (ARP32574_P050)
Reacts with
Human, Bovine, Horse, Rabbit, Guinea pig, Dog, Mouse, Rat, Zebrafish
Application
IHC, WB
$289.00
  pAb ARP32585_P050 OR13C5 Antibody - N-terminal region (ARP32585_P050)
Reacts with
Dog, Pig, Horse, Human, Rat, Bovine
Application
WB
$289.00
  pAb ARP32586_P050 HIPK2 Antibody - middle region (ARP32586_P050)
Reacts with
Rat, Horse, Guinea pig, Human, Dog, Mouse, Rabbit, Zebrafish, Bovine
Application
IHC, WB
$289.00
  pAb ARP32587_T100 KLF15 antibody - N-terminal region (ARP32587_T100)
Reacts with
Human, Rabbit, Horse, Bovine, Pig, Dog, Rat, Guinea pig, Mouse
Application
IHC, WB
$229.00
  pAb ARP32595_P050 RACGAP1 antibody - N-terminal region (ARP32595_P050)
Reacts with
Human, Bovine, Guinea pig, Dog, Rabbit, Rat, Mouse, Horse
Application
WB
$289.00
  pAb ARP32596_P050 UHRF1 Antibody - C-terminal region (ARP32596_P050)
Reacts with
Human
Application
WB
$289.00
  pAb ARP32598_P050 GTF2H4 antibody - N-terminal region (ARP32598_P050)
Reacts with
Human, Mouse, Dog, Rat, Guinea pig, Bovine, Goat
Application
WB
$289.00
  pAb ARP32603_T100 ABT1 antibody - middle region (ARP32603_T100)
Reacts with
Horse, Human, Bovine, Pig, Rabbit, Rat, Guinea pig, Dog, Mouse, Zebrafish
Application
IHC, WB
$229.00
  pAb ARP32606_P050 TFCP2L1 antibody - middle region (ARP32606_P050)
Reacts with
Bovine, Rat, Dog, Pig, Horse, Human, Rabbit, Guinea pig, Mouse, Zebrafish
Application
WB
$289.00
  pAb ARP32607_P050 CNOT7 antibody - middle region (ARP32607_P050)
Reacts with
Rat, Human, Dog, Pig, Horse, Goat, Rabbit, Guinea pig, Zebrafish, Mouse, Bovine, Yeast
Application
WB
$289.00
  pAb ARP32608_P050 HCFC2 antibody - C-terminal region (ARP32608_P050)
Reacts with
Human, Bovine, Dog, Pig, Rabbit, Rat, Guinea pig, Mouse, Horse
Application
WB
$289.00
  pAb ARP32609_P050 LASS2 antibody - N-terminal region (ARP32609_P050)
Reacts with
Human, Pig, Guinea pig, Mouse, Dog, Rabbit, Rat, Horse, Bovine
Application
IHC, WB
$289.00
  pAb ARP32612_P050 TBX21 antibody - middle region (ARP32612_P050)
Reacts with
Bovine, Dog, Pig, Human, Mouse, Rat, Rabbit, Guinea pig
Application
IHC, WB
$289.00
  pAb ARP32615_T100 HCLS1 antibody - N-terminal region (ARP32615_T100)
Reacts with
Human, Dog, Pig, Horse, Rabbit, Rat, Bovine, Zebrafish, Guinea pig, Mouse
Application
WB
$229.00
  pAb ARP32618_P050 HDAC2 antibody - C-terminal region (ARP32618_P050)
Reacts with
Human, Bovine, Dog, Pig, Rabbit, Rat, Mouse, Horse, Guinea pig, Yeast
Application
IHC, WB
$289.00

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Showing 631 - 660 of 3946