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Now Offering Over 85,203 Antibodies & 34,301 Antigens!

Transcription Factor Antibodies

Transcription factors are proteins that regulate gene expression by binding to DNA via one or more DNA-binding domains. This binding is achieved via a combination of electrostatic and van der waals forces and can occur at many closely-related sequences flanking different genes. Once bound to DNA directly or as part of a complex, they can promote or inhibit RNA polymerase recruitment, thereby acting as activators or repressors, respectively. Alternatively, transcription factors can act to recruit coactivators and corepressors or to catalyze histone acetylation and deacetylation. Transcription factors can function downstream of signaling cascades triggered by biological or environmental (ex. hypoxia, hyperthermia) stimuli to alter the expression of target genes. Ligand binding is necessary to activate some transcription factors as this can cause nuclear translocation and changes in the binding affinities for DNA and cofactors. During development, various stimuli can cause transcription factors to up- or down-regulate expression of specific genes at distinct time points to ensure proper development. Transcription factors can function as oncogenes or tumor suppressors and have thus been linked to various cancers. Accordingly, some therapeutic approaches in cancer therapy involve targeting transcription factor families[1].

1. Darnell JE Jr. 2002. Transcription factors as targets for cancer therapy. Nat Rev Cancer. Oct;2(10):740-9.

Transcription Factor Antibodies Top 20 Showcase

View the entire product list by clicking here.

Transcription Factors are involved in transcriptional regulation in the form of up regulation or down regulation acting as either repressors or activators of transcription. We have manufactured more than 3000 antibody products covering almost every known human and mouse transcription factors.

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Showing 631 - 660 of 3998
  Type Catalog # Product Product Images Price (USD)
  pAb ARP43147_P050 LOC683844 antibody - N-terminal region (ARP43147_P050)
Reacts with
Rat, Pig, Rabbit, Guinea pig, Bovine, Mouse, Human, Horse
Application
WB
$289.00
  pAb ARP51922_P050 ADPRH antibody - C-terminal region (ARP51922_P050)
Reacts with
Human, Dog, Pig, Horse, Bovine, Rat, Rabbit, Guinea pig, Mouse, Zebrafish
Application
WB
$289.00
  pAb ARP37061_P050 Hoxa1 Antibody - C-terminal region (ARP37061_P050)
Reacts with
Horse, Zebrafish, Rabbit, Mouse, Bovine, Dog, Pig, Rat, Guinea pig, Human
Application
WB
$289.00
  pAb ARP38627_P050 MED6 Antibody - N-terminal region (ARP38627_P050)
Reacts with
Human, Rat, Mouse, Dog, Pig, Horse, Rabbit, Guinea pig, Bovine, Zebrafish, Yeast
Application
WB
$289.00
  pAb ARP63674_P050 PGM2 antibody - C-terminal region (ARP63674_P050)
Reacts with
Human, Dog, Pig, Horse, Guinea pig, Mouse, Rabbit, Rat, Zebrafish, Bovine
Application
WB
$289.00
  pAb ARP50617_P050 MBTD1 Antibody - N-terminal region (ARP50617_P050)
Reacts with
Mouse, Dog, Bovine, Pig, Horse, Rabbit, Rat, Guinea pig, Human, Zebrafish, Yeast
Application
WB
$289.00
  pAb ARP63111_P050 DACT1 antibody - middle region (ARP63111_P050)
Reacts with
Mouse, Human, Rat, Bovine, Pig, Dog, Rabbit, Guinea pig, Zebrafish
Application
WB
$289.00
  pAb ARP50800_P050 ZNF362 Antibody - N-terminal region (ARP50800_P050)
Reacts with
Mouse, Rat, Dog, Bovine, Human, Rabbit, Guinea pig, Zebrafish
Application
WB
$289.00
  pAb ARP48867_P050 Trmt5 antibody - C-terminal region (ARP48867_P050)
Reacts with
Rat, Horse, Rabbit, Guinea pig, Human, Bovine, Mouse, Dog
Application
WB
$289.00
  pAb ARP70065_P050 CSRNP2 Antibody - C-terminal region (ARP70065_P050)
Reacts with
Human, Horse, Guinea pig, Rat, Bovine, Dog, Rabbit, Sheep
Application
WB
$289.00
  pAb ARP34806_T100 ZNF627 antibody - N-terminal region (ARP34806_T100)
Reacts with
Human
Application
WB
$229.00
  pAb ARP55440_P050 IGJ antibody - N-terminal region (ARP55440_P050)
Reacts with
Human, Mouse, Rat, Yeast, Dog, Pig, Bovine
Application
WB
$289.00
  pAb ARP72604_P050 NFE2L2 Antibody - C-terminal region (ARP72604_P050)
Reacts with
Human, Pig, Bovine, Dog, Horse, Rat, Rabbit, Guinea pig
Application
WB
$289.00
  pAb ARP31225_P050 RARB Antibody - N-terminal region (ARP31225_P050)
Reacts with
Bovine, Human, Dog, Horse, Rabbit, Guinea pig, Rat, Mouse
Application
WB
$289.00
  pAb ARP62310_P050 PRSS58 antibody - C-terminal region (ARP62310_P050)
Reacts with
Pig, Bovine, Human, Rabbit, Rat, Guinea pig, Dog, Horse, Mouse
Application
WB
$289.00
  pAb ARP35732_P050 ILF2 Antibody - N-terminal region (ARP35732_P050)
Reacts with
Rat, Human, Dog, Bovine, Horse, Rabbit, Guinea pig, Mouse, Zebrafish
Application
WB
$289.00
  pAb ARP56720_P050 Pskh1 antibody - C-terminal region (ARP56720_P050)
Reacts with
Dog, Horse, Rabbit, Rat, Guinea pig, Human, Bovine, Mouse, Zebrafish
Application
WB
$289.00
  pAb ARP37930_P050 Vgll2 Antibody - C-terminal region (ARP37930_P050)
Reacts with
Mouse, Human, Rat, Dog, Horse, Rabbit, Bovine, Pig
Application
WB
$289.00
  pAb ARP40005_P050 ZNF707 Antibody - C-terminal region (ARP40005_P050)
Reacts with
Rat, Human, Mouse, Horse, Pig
Application
WB
$289.00
  pAb ARP64139_P050 CD109 antibody - middle region (ARP64139_P050)
Reacts with
Bovine, Dog, Rat, Human, Pig, Horse, Guinea pig
Application
WB
$289.00
  pAb ARP35520_P050 Gm6185 antibody - middle region (ARP35520_P050)
Reacts with
Human, Rat, Horse, Rabbit, Guinea pig, Dog, Bovine
Application
WB
$289.00
  pAb ARP36377_P050 DDX23 antibody - C-terminal region (ARP36377_P050)
Reacts with
Bovine, Human, Rat, Mouse, Dog, Horse, Rabbit, Guinea pig, Zebrafish, Yeast
Application
WB
$289.00
  pAb ARP60556_P050 STK40 Antibody - N-terminal region (ARP60556_P050)
Reacts with
Dog, Horse, Rabbit, Rat, Guinea pig, Bovine, Human, Mouse
Application
WB
$289.00
  pAb ARP67596_P050 KCTD1 Antibody - middle region (ARP67596_P050)
Reacts with
Mouse, Horse, Human, Dog, Pig, Goat, Rat, Guinea pig, Bovine, Rabbit
Application
WB
$289.00
  pAb ARP32256_P050 NR2F6 antibody - N-terminal region (ARP32256_P050)
Reacts with
Human, Dog, Bovine, Pig, Guinea pig, Rat, Mouse
Application
IHC, WB
$289.00
  pAb ARP46438_P050 COX6A1 antibody - N-terminal region (ARP46438_P050)
Reacts with
Human
Application
WB
$289.00
  pAb ARP38129_P050 IRF1 Antibody - C-terminal region (ARP38129_P050)
Reacts with
Guinea pig, Human, Horse, Rat, Bovine, Sheep, Rabbit, Dog, Mouse
Application
WB
$289.00
  pAb ARP37131_P050 Sfpi1 Antibody - N-terminal region (ARP37131_P050)
Reacts with
Mouse, Rat
Application
WB
$289.00
  pAb ARP38802_P050 TAF6L Antibody - C-terminal region (ARP38802_P050)
Reacts with
Human, Bovine, Pig, Rat, Dog, Rabbit, Guinea pig, Mouse
Application
WB
$289.00
  pAb ARP63846_P050 SCG5 antibody - C-terminal region (ARP63846_P050)
Reacts with
Human, Pig, Horse, Rat, Mouse, Bovine, Dog, Rabbit, Guinea pig
Application
WB
$289.00

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Showing 631 - 660 of 3998