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Now Offering Over 85,203 Antibodies & 34,301 Antigens!

Transcription Factor Antibodies

Transcription factors are proteins that regulate gene expression by binding to DNA via one or more DNA-binding domains. This binding is achieved via a combination of electrostatic and van der waals forces and can occur at many closely-related sequences flanking different genes. Once bound to DNA directly or as part of a complex, they can promote or inhibit RNA polymerase recruitment, thereby acting as activators or repressors, respectively. Alternatively, transcription factors can act to recruit coactivators and corepressors or to catalyze histone acetylation and deacetylation. Transcription factors can function downstream of signaling cascades triggered by biological or environmental (ex. hypoxia, hyperthermia) stimuli to alter the expression of target genes. Ligand binding is necessary to activate some transcription factors as this can cause nuclear translocation and changes in the binding affinities for DNA and cofactors. During development, various stimuli can cause transcription factors to up- or down-regulate expression of specific genes at distinct time points to ensure proper development. Transcription factors can function as oncogenes or tumor suppressors and have thus been linked to various cancers. Accordingly, some therapeutic approaches in cancer therapy involve targeting transcription factor families[1].

1. Darnell JE Jr. 2002. Transcription factors as targets for cancer therapy. Nat Rev Cancer. Oct;2(10):740-9.

Transcription Factor Antibodies Top 20 Showcase

View the entire product list by clicking here.

Transcription Factors are involved in transcriptional regulation in the form of up regulation or down regulation acting as either repressors or activators of transcription. We have manufactured more than 3000 antibody products covering almost every known human and mouse transcription factors.

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Showing 631 - 660 of 4061
  Type Catalog # Product Product Images Price (USD)
  pAb ARP30331_P050 CDK2 antibody - middle region (ARP30331_P050)
Reacts with
Bovine, Goat, Guinea pig, Human, Mouse, Rabbit, Rat, Sheep, Zebrafish
Application
WB
$289.00
  pAb ARP36287_P050 PRDM6 Antibody - C-terminal region (ARP36287_P050)
Reacts with
Bovine, Rat, Dog, Pig, Horse, Rabbit, Guinea pig, Mouse, Human, Zebrafish
Application
WB
$289.00
  pAb ARP32320_T100 HNF1B antibody - N-terminal region (ARP32320_T100)
Reacts with
Rat, Zebrafish, Human, Dog, Bovine, Horse, Guinea pig, Mouse
Application
WB
$229.00
  pAb ARP38855_P050 Hoxa2 antibody - N-terminal region (ARP38855_P050)
Reacts with
Human, Horse, Rabbit, Dog, Bovine, Pig, Rat, Guinea pig, Mouse, Zebrafish
Application
WB
$289.00
  pAb ARP31220_P050 PAX2 Antibody - middle region (ARP31220_P050)
Reacts with
Sheep, Bovine, Dog, Pig, Horse, Zebrafish, Rabbit, Human, Rat, Guinea pig, Mouse
Application
WB
$289.00
  pAb ARP36356_P050 DHX16 antibody - N-terminal region (ARP36356_P050)
Reacts with
Human, Bovine, Dog, Pig, Horse, Goat, Rabbit, Mouse, Rat, Guinea pig, Zebrafish, Yeast
Application
WB
$289.00
  pAb ARP32033_P050 NAB2 Antibody - N-terminal region (ARP32033_P050)
Reacts with
Dog, Pig, Horse, Rabbit, Human, Bovine
Application
WB
$289.00
  pAb ARP37438_P050 Foxp3 Antibody - N-terminal region (ARP37438_P050)
Reacts with
Rat, Mouse, Rabbit
Application
WB
$289.00
  pAb ARP32187_P050 KLF3 Antibody - C-terminal region (ARP32187_P050)
Reacts with
Human, Pig, Rat, Bovine, Dog, Horse, Rabbit, Mouse, Guinea pig
Application
WB
$289.00
  pAb ARP49192_P050 Mgat5b antibody - C-terminal region (ARP49192_P050)
Reacts with
Rat, Bovine, Dog, Pig, Horse, Mouse, Guinea pig, Human, Zebrafish
Application
WB
$289.00
  pAb ARP39531_P050 NR1I2 Antibody - N-terminal region (ARP39531_P050)
Reacts with
Human
Application
WB
$289.00
  pAb ARP35894_P050 ZFYVE26 Antibody - N-terminal region (ARP35894_P050)
Reacts with
Human, Rabbit, Rat, Bovine, Dog, Pig, Horse, Guinea pig, Mouse
Application
WB
$289.00
  pAb ARP63493_P050 Il15ra antibody - N-terminal region (ARP63493_P050)
Reacts with
Pig, Bovine, Human, Dog, Horse, Rabbit, Rat, Guinea pig, Mouse
Application
WB
$289.00
  pAb ARP53574_P050 AURKA Antibody - middle region (ARP53574_P050)
Reacts with
Human, Bovine, Dog, Horse, Mouse, Rabbit, Rat, Guinea pig, Zebrafish, Sheep
Application
WB
$289.00
  pAb ARP34165_P050 RCVRN antibody - C-terminal region (ARP34165_P050)
Reacts with
Horse, Human, Bovine, Dog, Rat, Pig, Mouse, Rabbit, Guinea pig
Application
WB
$289.00
  pAb ARP64835_P050 NADK antibody - C-terminal region (ARP64835_P050)
Reacts with
Mouse, Human, Dog, Bovine, Horse, Rat, Rabbit, Guinea pig, Zebrafish
Application
WB
$289.00
  pAb ARP50985_P050 ZNF679 Antibody - N-terminal region (ARP50985_P050)
Reacts with
Human
Application
WB
$289.00
  pAb ARP61955_P050 HMGN3 antibody - middle region (ARP61955_P050)
Reacts with
Dog, Horse, Rabbit, Guinea pig, Rat, Human, Mouse, Bovine
Application
WB
$289.00
  pAb ARP40415_P050 SRGN antibody - N-terminal region (ARP40415_P050)
Reacts with
Human, Rat, Mouse, Rabbit
Application
WB
$289.00
  pAb ARP30769_P050 VAPA Antibody - C-terminal region (ARP30769_P050)
Reacts with
Human, Dog, Horse, Rabbit, Rat, Mouse, Pig, Bovine, Guinea pig
Application
WB
$289.00
  pAb ARP54337_P050 Igfbp5 antibody - middle region (ARP54337_P050)
Reacts with
Sheep, Human, Pig, Dog, Goat, Rabbit, Rat, Bovine, Mouse, Horse, Guinea pig
Application
WB
$289.00
  pAb ARP38427_P050 ZNF284 Antibody - N-terminal region (ARP38427_P050)
Reacts with
Bovine, Pig, Rat, Dog, Human, Mouse, Horse
Application
WB
$289.00
  pAb ARP39224_P050 2700060E02Rik antibody - C-terminal region (ARP39224_P050)
Reacts with
Dog, Zebrafish, Pig, Horse, Rabbit, Rat, Guinea pig, Mouse, Bovine, Human, Yeast
Application
WB
$289.00
  pAb ARP47578_P050 ZNF397 Antibody - middle region (ARP47578_P050)
Reacts with
Human, Bovine, Pig, Horse, Rabbit, Rat, Guinea pig, Dog, Mouse, Goat
Application
WB
$289.00
  pAb ARP37131_P050 Sfpi1 Antibody - N-terminal region (ARP37131_P050)
Reacts with
Mouse, Rat
Application
WB
$289.00
  pAb ARP59371_P050 RWDD3 antibody - middle region (ARP59371_P050)
Reacts with
Human, Rat, Guinea pig, Dog, Mouse
Application
WB
$289.00
  pAb ARP60528_P050 Vps25 Antibody - C-terminal region (ARP60528_P050)
Reacts with
Mouse, Dog, Human, Rat, Bovine, Guinea pig
Application
WB
$289.00
  pAb ARP41526_P050 Xpnpep2 antibody - C-terminal region (ARP41526_P050)
Reacts with
Mouse, Human, Horse, Rat, Bovine, Guinea pig, Dog, Rabbit
Application
WB
$289.00
  pAb ARP72147_P050 SOHLH2 Antibody - N-terminal region (ARP72147_P050)
Reacts with
Human, Dog, Rat, Guinea pig
Application
WB
$289.00
  pAb ARP39651_P050 Bhlhe41 antibody - N-terminal region (ARP39651_P050)
Reacts with
Human, Mouse, Bovine, Horse, Rat, Guinea pig, Dog
Application
WB
$289.00

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Showing 631 - 660 of 4061