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Now Offering Over 85,203 Antibodies & 34,301 Antigens!

Transcription Factor Antibodies

Transcription factors are proteins that regulate gene expression by binding to DNA via one or more DNA-binding domains. This binding is achieved via a combination of electrostatic and van der waals forces and can occur at many closely-related sequences flanking different genes. Once bound to DNA directly or as part of a complex, they can promote or inhibit RNA polymerase recruitment, thereby acting as activators or repressors, respectively. Alternatively, transcription factors can act to recruit coactivators and corepressors or to catalyze histone acetylation and deacetylation. Transcription factors can function downstream of signaling cascades triggered by biological or environmental (ex. hypoxia, hyperthermia) stimuli to alter the expression of target genes. Ligand binding is necessary to activate some transcription factors as this can cause nuclear translocation and changes in the binding affinities for DNA and cofactors. During development, various stimuli can cause transcription factors to up- or down-regulate expression of specific genes at distinct time points to ensure proper development. Transcription factors can function as oncogenes or tumor suppressors and have thus been linked to various cancers. Accordingly, some therapeutic approaches in cancer therapy involve targeting transcription factor families[1].

1. Darnell JE Jr. 2002. Transcription factors as targets for cancer therapy. Nat Rev Cancer. Oct;2(10):740-9.

Transcription Factor Antibodies Top 20 Showcase

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Transcription Factors are involved in transcriptional regulation in the form of up regulation or down regulation acting as either repressors or activators of transcription. We have manufactured more than 3000 antibody products covering almost every known human and mouse transcription factors.

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Showing 631 - 660 of 3998
  Type Catalog # Product Product Images Price (USD)
  pAb ARP62393_P050 LY6G5B antibody - N-terminal region (ARP62393_P050)
Reacts with
Human, Dog, Pig, Horse
Application
WB
$289.00
  pAb ARP39240_P050 ZNF681 Antibody - middle region (ARP39240_P050)
Reacts with
Human
Application
WB
$289.00
  pAb ARP35845_P050 DUX1 Antibody - N-terminal region (ARP35845_P050)
Reacts with
Human
Application
WB
$289.00
  pAb ARP56946_P050 Rasl12 antibody - N-terminal region (ARP56946_P050)
Reacts with
Human, Rat, Mouse, Bovine, Pig, Horse, Rabbit, Guinea pig
Application
WB
$289.00
  pAb ARP37944_P050 Zhx2 Antibody - C-terminal region (ARP37944_P050)
Reacts with
Rat, Mouse
Application
WB
$289.00
  pAb ARP64386_P050 CA13 antibody - N-terminal region (ARP64386_P050)
Reacts with
Bovine, Rat, Pig, Horse, Rabbit, Dog, Human, Mouse, Guinea pig
Application
WB
$289.00
  pAb ARP51731_P050 HSFY2 Antibody - middle region (ARP51731_P050)
Reacts with
Human, Dog
Application
WB
$289.00
  pAb ARP33286_T100 SHOX2 antibody - middle region (ARP33286_T100)
Reacts with
Human, Bovine, Dog, Zebrafish, Horse, Mouse, Rat, Guinea pig, Rabbit
Application
WB
$229.00
  pAb ARP36247_P050 Olig3 antibody - N-terminal region (ARP36247_P050)
Reacts with
Rat, Dog, Pig, Rabbit, Bovine, Guinea pig, Mouse, Human, Horse
Application
WB
$289.00
  pAb ARP64530_P050 STXBP3 antibody - C-terminal region (ARP64530_P050)
Reacts with
Rabbit, Rat, Human, Mouse, Bovine, Dog, Horse, Pig, Zebrafish
Application
WB
$289.00
  pAb ARP34597_P050 PRDM11 Antibody - C-terminal region (ARP34597_P050)
Reacts with
Human, Bovine, Dog, Pig, Mouse, Horse, Rabbit, Rat
Application
WB
$289.00
  pAb ARP32526_P050 Zbtb38 antibody - C-terminal region (ARP32526_P050)
Reacts with
Zebrafish, Human, Pig, Rat, Bovine, Guinea pig, Mouse, Dog, Horse
Application
WB
$289.00
  pAb ARP39847_P050 DHRSX antibody - N-terminal region (ARP39847_P050)
Reacts with
Bovine, Human, Rat, Yeast
Application
WB
$289.00
  pAb P100591_T100 NANOG antibody - N-terminal region (P100591_T100)
Reacts with
Human, Pig
Application
WB
$229.00
  pAb ARP30966_P050 Tcf3 Antibody - C-terminal region (ARP30966_P050)
Reacts with
Dog, Pig, Guinea pig, Human, Rat, Bovine, Mouse, Zebrafish, Horse, Rabbit
Application
WB
$289.00
  pAb ARP42659_P050 Nrbf2 antibody - N-terminal region (ARP42659_P050)
Reacts with
Mouse, Horse, Rabbit, Rat, Dog, Bovine, Human, Zebrafish
Application
WB
$289.00
  pAb ARP33528_P050 ZNF232 Antibody - N-terminal region (ARP33528_P050)
Reacts with
Pig, Human, Mouse, Horse, Rat, Guinea pig, Dog, Bovine, Rabbit
Application
WB
$289.00
  pAb ARP32443_T100 LHX3 antibody - middle region (ARP32443_T100)
Reacts with
Human, Rat, Pig, Bovine, Zebrafish, Guinea pig, Mouse, Dog, Horse
Application
WB
$229.00
  pAb ARP63640_P050 CDC73 antibody - C-terminal region (ARP63640_P050)
Reacts with
Dog, Bovine, Rat, Horse, Rabbit, Human, Mouse, Zebrafish
Application
WB
$289.00
  pAb ARP47578_P050 ZNF397 Antibody - middle region (ARP47578_P050)
Reacts with
Human, Bovine, Pig, Horse, Rabbit, Rat, Guinea pig, Dog, Mouse, Goat
Application
WB
$289.00
  pAb ARP37246_P050 Atf7ip Antibody - middle region (ARP37246_P050)
Reacts with
Mouse, Pig, Rat
Application
WB
$289.00
  pAb ARP66128_P050 AKNA Antibody - C-terminal region (ARP66128_P050)
Reacts with
Human, Rabbit, Rat
Application
WB
$289.00
  pAb ARP71985_P050 WDR31 Antibody - middle region (ARP71985_P050)
Reacts with
Human, Guinea pig, Rat, Bovine, Mouse
Application
WB
$289.00
  pAb ARP31097_P050 HSF2 antibody - N-terminal region (ARP31097_P050)
Reacts with
Bovine, Dog, Pig, Horse, Rabbit, Rat, Guinea pig, Human, Zebrafish, Mouse
Application
WB
$289.00
  pAb ARP30108_P050 Tsc22d4 Antibody - N-terminal region (ARP30108_P050)
Reacts with
Rat, Human, Dog, Rabbit, Guinea pig, Bovine, Mouse, Horse
Application
WB
$289.00
  pAb ARP61198_P050 GET4 antibody - N-terminal region (ARP61198_P050)
Reacts with
Human, Mouse, Rat, Dog, Guinea pig, Horse, Bovine, Zebrafish
Application
WB
$289.00
  pAb ARP31516_P050 Prdm4 Antibody - C-terminal region (ARP31516_P050)
Reacts with
Rabbit, Rat, Human, Dog, Horse, Yeast, Bovine, Pig, Mouse
Application
WB
$289.00
  pAb ARP62578_P050 OBFC1 antibody - C-terminal region (ARP62578_P050)
Reacts with
Human, Horse, Dog, Pig, Mouse, Rat, Guinea pig, Bovine
Application
WB
$289.00
  pAb ARP33432_T100 TFAP2B antibody - C-terminal region (ARP33432_T100)
Reacts with
Human, Dog, Rat, Mouse, Horse, Rabbit, Guinea pig, Bovine, Zebrafish, Sheep
Application
WB
$229.00
  pAb ARP39395_P050 SLC2A4RG Antibody - C-terminal region (ARP39395_P050)
Reacts with
Human, Rat, Mouse
Application
WB
$289.00

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Showing 631 - 660 of 3998