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Now Offering Over 85,203 Antibodies & 34,301 Antigens!

Transcription Factor Antibodies

Transcription factors are proteins that regulate gene expression by binding to DNA via one or more DNA-binding domains. This binding is achieved via a combination of electrostatic and van der waals forces and can occur at many closely-related sequences flanking different genes. Once bound to DNA directly or as part of a complex, they can promote or inhibit RNA polymerase recruitment, thereby acting as activators or repressors, respectively. Alternatively, transcription factors can act to recruit coactivators and corepressors or to catalyze histone acetylation and deacetylation. Transcription factors can function downstream of signaling cascades triggered by biological or environmental (ex. hypoxia, hyperthermia) stimuli to alter the expression of target genes. Ligand binding is necessary to activate some transcription factors as this can cause nuclear translocation and changes in the binding affinities for DNA and cofactors. During development, various stimuli can cause transcription factors to up- or down-regulate expression of specific genes at distinct time points to ensure proper development. Transcription factors can function as oncogenes or tumor suppressors and have thus been linked to various cancers. Accordingly, some therapeutic approaches in cancer therapy involve targeting transcription factor families[1].

1. Darnell JE Jr. 2002. Transcription factors as targets for cancer therapy. Nat Rev Cancer. Oct;2(10):740-9.

Transcription Factor Antibodies Top 20 Showcase

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Transcription Factors are involved in transcriptional regulation in the form of up regulation or down regulation acting as either repressors or activators of transcription. We have manufactured more than 3000 antibody products covering almost every known human and mouse transcription factors.

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Showing 631 - 660 of 3976
  Type Catalog # Product Product Images Price (USD)
  pAb ARP62354_P050 Pitpnc1 antibody - middle region (ARP62354_P050)
Reacts with
Human, Pig, Rat, Dog, Horse, Rabbit, Guinea pig, Mouse, Zebrafish
Application
WB
$289.00
  pAb ARP64778_P050 MMP28 antibody - C-terminal region (ARP64778_P050)
Reacts with
Human, Horse, Dog, Bovine
Application
WB
$289.00
  pAb ARP35960_P050 MESP1 antibody - C-terminal region (ARP35960_P050)
Reacts with
Human, Bovine, Horse
Application
WB
$289.00
  pAb ARP39935_P050 NPAS3 Antibody - middle region (ARP39935_P050)
Reacts with
Bovine, Pig, Mouse, Human, Rat, Zebrafish, Dog, Horse, Rabbit, Goat, Guinea pig
Application
WB
$289.00
  pAb ARP42116_P050 Timp2 antibody - C-terminal region (ARP42116_P050)
Reacts with
Mouse, Human, Pig, Sheep, Bovine, Dog, Horse, Rat, Rabbit, Guinea pig, Zebrafish
Application
WB
$289.00
  pAb ARP45630_P050 Rorb antibody - N-terminal region (ARP45630_P050)
Reacts with
Zebrafish, Sheep, Human, Goat, Rat, Bovine, Dog, Pig, Horse, Rabbit, Guinea pig, Mouse, Yeast
Application
WB
$289.00
  pAb ARP34179_P050 PAX8 Antibody - C-terminal region (ARP34179_P050)
Reacts with
Bovine, Horse, Pig, Dog, Human, Mouse, Rat, Guinea pig
Application
WB
$289.00
  pAb ARP60556_P050 STK40 Antibody - N-terminal region (ARP60556_P050)
Reacts with
Dog, Horse, Rabbit, Rat, Guinea pig, Bovine, Human, Mouse
Application
WB
$289.00
  pAb ARP41879_P050 KLK3 antibody - middle region (ARP41879_P050)
Reacts with
Human, Mouse, Rat, Dog
Application
WB
$289.00
  pAb ARP34499_P050 VAX1 Antibody - N-terminal region (ARP34499_P050)
Reacts with
Bovine, Pig, Human, Dog, Rat, Mouse
Application
WB
$289.00
  pAb ARP72326_P050 ZNF737 Antibody - N-terminal region (ARP72326_P050)
Reacts with
Human
Application
WB
$289.00
  pAb ARP52180_P050 Slu7 antibody - middle region (ARP52180_P050)
Reacts with
Rat, Human, Dog, Pig, Horse, Rabbit, Guinea pig, Bovine, Mouse, Zebrafish
Application
WB
$289.00
  pAb ARP33359_T100 SSTR4 antibody - middle region (ARP33359_T100)
Reacts with
Mouse, Rabbit
Application
WB
$229.00
  pAb ARP37533_P050 Zfp445 Antibody - middle region (ARP37533_P050)
Reacts with
Mouse, Rat
Application
WB
$289.00
  pAb ARP37068_P050 Hoxb7 antibody - middle region (ARP37068_P050)
Reacts with
Pig, Dog, Bovine, Horse, Rabbit, Mouse, Human, Rat
Application
WB
$289.00
  pAb ARP38446_P050 MED7 antibody - C-terminal region (ARP38446_P050)
Reacts with
Human, Bovine, Horse, Rat, Guinea pig, Dog, Rabbit, Mouse
Application
WB, CHIP
$289.00
  pAb ARP44397_P050 EG546729 antibody - C-terminal region (ARP44397_P050)
Reacts with
Rat, Human, Mouse, Dog, Rabbit, Bovine, Pig, Horse
Application
WB
$289.00
  pAb ARP45622_P050 RORC antibody - N-terminal region (ARP45622_P050)
Reacts with
Pig, Bovine, Horse, Human, Rat, Guinea pig, Dog, Mouse, Rabbit
Application
WB, IHC
$289.00
  pAb ARP38802_P050 TAF6L Antibody - C-terminal region (ARP38802_P050)
Reacts with
Human, Bovine, Pig, Rat, Dog, Rabbit, Guinea pig, Mouse
Application
WB
$289.00
  pAb ARP38138_P050 Aff3 antibody - C-terminal region (ARP38138_P050)
Reacts with
Mouse, Rat, Dog, Pig, Horse, Rabbit, Human, Bovine, Zebrafish
Application
WB
$289.00
  pAb ARP30901_P050 CBFB Antibody - N-terminal region (ARP30901_P050)
Reacts with
Human, Bovine, Dog, Rabbit, Rat, Pig, Mouse, Zebrafish, Yeast, Horse, Guinea pig
Application
WB
$289.00
  pAb ARP50801_P050 ZNF362 Antibody - C-terminal region (ARP50801_P050)
Reacts with
Mouse, Rat, Dog, Horse, Rabbit, Guinea pig, Human, Zebrafish, Bovine
Application
WB
$289.00
  pAb ARP32262_P050 NR2E3 Antibody - middle region (ARP32262_P050)
Reacts with
Human, Bovine, Horse, Zebrafish, Pig, Rat, Guinea pig, Mouse
Application
WB
$289.00
  pAb ARP51129_P050 LOC652119 Antibody - N-terminal region (ARP51129_P050)
Reacts with
Human
Application
WB
$289.00
  pAb ARP30622_P050 TNFRSF10A antibody - C-terminal region (ARP30622_P050)
Reacts with
Human, Mouse
Application
WB
$289.00
  pAb ARP36967_P050 Rel Antibody - C-terminal region (ARP36967_P050)
Reacts with
Mouse
Application
WB
$289.00
  pAb ARP63015_P050 Msn antibody - C-terminal region (ARP63015_P050)
Reacts with
Dog, Rat, Pig, Horse, Rabbit, Guinea pig, Human, Mouse, Bovine, Zebrafish, Yeast
Application
WB
$289.00
  pAb ARP64810_P050 PKP4 antibody - N-terminal region (ARP64810_P050)
Reacts with
Human, Bovine, Pig, Dog, Horse, Rabbit, Mouse, Rat, Guinea pig
Application
WB
$289.00
  pAb ARP34555_P050 Rnf141 antibody - N-terminal region (ARP34555_P050)
Reacts with
Human, Rat, Guinea pig, Mouse, Dog, Horse, Rabbit, Bovine
Application
WB
$289.00
  pAb ARP34861_T100 TRIM9 antibody - C-terminal region (ARP34861_T100)
Reacts with
Human, Rabbit
Application
WB
$229.00

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Showing 631 - 660 of 3976