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Now Offering Over 85,203 Antibodies & 34,301 Antigens!

Transcription Factor Antibodies

Transcription factors are proteins that regulate gene expression by binding to DNA via one or more DNA-binding domains. This binding is achieved via a combination of electrostatic and van der waals forces and can occur at many closely-related sequences flanking different genes. Once bound to DNA directly or as part of a complex, they can promote or inhibit RNA polymerase recruitment, thereby acting as activators or repressors, respectively. Alternatively, transcription factors can act to recruit coactivators and corepressors or to catalyze histone acetylation and deacetylation. Transcription factors can function downstream of signaling cascades triggered by biological or environmental (ex. hypoxia, hyperthermia) stimuli to alter the expression of target genes. Ligand binding is necessary to activate some transcription factors as this can cause nuclear translocation and changes in the binding affinities for DNA and cofactors. During development, various stimuli can cause transcription factors to up- or down-regulate expression of specific genes at distinct time points to ensure proper development. Transcription factors can function as oncogenes or tumor suppressors and have thus been linked to various cancers. Accordingly, some therapeutic approaches in cancer therapy involve targeting transcription factor families[1].

1. Darnell JE Jr. 2002. Transcription factors as targets for cancer therapy. Nat Rev Cancer. Oct;2(10):740-9.

Transcription Factor Antibodies Top 20 Showcase

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Transcription Factors are involved in transcriptional regulation in the form of up regulation or down regulation acting as either repressors or activators of transcription. We have manufactured more than 3000 antibody products covering almost every known human and mouse transcription factors.

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Showing 631 - 660 of 4137
  Type Catalog # Product Product Images Price (USD)
  pAb ARP62340_P050 Ip6k1 antibody - N-terminal region (ARP62340_P050)
Reacts with
Human, Pig, Horse, Rat, Guinea pig, Mouse, Bovine, Rabbit, Dog
Application
WB
$289.00
  pAb ARP38627_P050 MED6 Antibody - N-terminal region (ARP38627_P050)
Reacts with
Human, Rat, Mouse, Dog, Pig, Horse, Rabbit, Guinea pig, Bovine, Zebrafish, Yeast
Application
WB
$289.00
  pAb ARP64775_P050 JMY antibody - N-terminal region (ARP64775_P050)
Reacts with
Rat, Human, Mouse, Guinea pig, Bovine
Application
WB
$289.00
  pAb ARP35489_P050 KCNIP2 antibody - C-terminal region (ARP35489_P050)
Reacts with
Pig, Human, Bovine, Rat, Mouse, Dog, Horse, Rabbit, Guinea pig
Application
WB
$289.00
  pAb ARP40842_P050 Hsd17b11 antibody - middle region (ARP40842_P050)
Reacts with
Dog, Horse, Rabbit, Rat, Pig, Bovine, Human, Mouse
Application
WB
$289.00
  pAb ARP45395_P050 Mfng antibody - middle region (ARP45395_P050)
Reacts with
Zebrafish, Mouse, Human, Dog, Pig, Horse, Rat, Guinea pig, Bovine, Rabbit
Application
WB
$289.00
  pAb ARP37831_P050 SOHLH1 Antibody - C-terminal region (ARP37831_P050)
Reacts with
Human
Application
WB
$289.00
  pAb ARP41590_P050 VSIG4 antibody - N-terminal region (ARP41590_P050)
Reacts with
Pig, Horse, Rabbit, Human, Bovine, Dog, Guinea pig, Mouse, Rat
Application
WB
$289.00
  pAb ARP37533_P050 Zfp445 Antibody - middle region (ARP37533_P050)
Reacts with
Mouse, Rat
Application
WB
$289.00
  pAb ARP41634_P050 Pcdh10 antibody - C-terminal region (ARP41634_P050)
Reacts with
Rat, Dog, Mouse, Bovine, Rabbit, Guinea pig, Human, Zebrafish
Application
WB
$289.00
  pAb ARP33600_P050 Cbll1 antibody - C-terminal region (ARP33600_P050)
Reacts with
Human, Rat, Mouse, Bovine, Horse, Pig, Dog
Application
WB
$289.00
  pAb ARP39702_P050 IKZF3 Antibody - middle region (ARP39702_P050)
Reacts with
Human, Bovine, Rat, Dog, Pig, Horse, Rabbit, Guinea pig, Mouse, Yeast
Application
WB
$289.00
  pAb ARP37981_P050 PITX2 antibody - N-terminal region (ARP37981_P050)
Reacts with
Human, Pig, Rabbit, Mouse, Rat
Application
WB
$289.00
  pAb ARP53574_P050 AURKA Antibody - middle region (ARP53574_P050)
Reacts with
Human, Bovine, Dog, Horse, Mouse, Rabbit, Rat, Guinea pig, Zebrafish, Sheep
Application
WB
$289.00
  pAb ARP67185_P050 MTERFD3 Antibody - N-terminal region (ARP67185_P050)
Reacts with
Human, Dog, Pig, Bovine, Horse, Rat, Mouse, Rabbit, Guinea pig
Application
WB
$289.00
  pAb ARP32334_P050 Id3 antibody - middle region (ARP32334_P050)
Reacts with
Pig, Sheep, Rabbit, Mouse, Rat, Human, Bovine, Dog, Horse, Guinea pig
Application
WB
$289.00
  pAb ARP51721_P050 SSX2 Antibody - middle region (ARP51721_P050)
Reacts with
Human
Application
WB
$289.00
  pAb ARP30473_P050 BAK1 antibody - N-terminal region (ARP30473_P050)
Reacts with
Human, Horse
Application
WB
$289.00
  pAb ARP34488_P050 NKX6-3 Antibody - C-terminal region (ARP34488_P050)
Reacts with
Human, Rat, Rabbit, Mouse
Application
WB
$289.00
  pAb ARP37096_P050 Msx3 Antibody - C-terminal region (ARP37096_P050)
Reacts with
Mouse, Rat
Application
WB
$289.00
  pAb ARP38802_P050 TAF6L Antibody - C-terminal region (ARP38802_P050)
Reacts with
Human, Bovine, Pig, Rat, Dog, Rabbit, Guinea pig, Mouse
Application
WB
$289.00
  pAb ARP64806_P050 PACS1 antibody - C-terminal region (ARP64806_P050)
Reacts with
Human, Bovine, Dog, Rat, Pig, Horse, Rabbit, Guinea pig, Mouse
Application
WB
$289.00
  pAb ARP34467_P050 Klhl1 antibody - C-terminal region (ARP34467_P050)
Reacts with
Human, Rat, Bovine, Dog, Pig, Horse, Rabbit, Guinea pig, Mouse
Application
WB
$289.00
  pAb ARP34203_T100 ASH2L antibody - N-terminal region (ARP34203_T100)
Reacts with
Human, Rat, Bovine, Dog, Horse, Guinea pig, Mouse
Application
IHC, WB
$229.00
  pAb ARP47709_P050 ZSCAN21 Antibody - middle region (ARP47709_P050)
Reacts with
Mouse, Pig, Human, Dog, Horse, Guinea pig, Rat, Bovine, Rabbit
Application
WB
$289.00
  pAb ARP56187_P050 LOC100362453 antibody - C-terminal region (ARP56187_P050)
Reacts with
Rat, Human, Dog, Zebrafish, Pig, Horse, Rabbit, Guinea pig, Yeast, Mouse, Bovine
Application
WB
$289.00
  pAb ARP60158_P050 DAXX Antibody - C-terminal region (ARP60158_P050)
Reacts with
Human, Horse, Rat, Dog
Application
WB
$289.00
  pAb ARP51233_P050 Phf23 antibody - N-terminal region (ARP51233_P050)
Reacts with
Bovine, Human, Dog, Pig, Rabbit, Rat, Guinea pig, Mouse
Application
WB
$289.00
  pAb ARP72114_P050 SSX2B Antibody - middle region (ARP72114_P050)
Reacts with
Human
Application
WB
$289.00
  pAb ARP50246_P050 Pigu antibody - N-terminal region (ARP50246_P050)
Reacts with
Human, Pig, Dog, Bovine, Horse, Rabbit, Rat, Mouse, Zebrafish, Guinea pig
Application
WB
$289.00

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Showing 631 - 660 of 4137