website statistics
Account Login 

Aviva Systems Biology office will be closed for Memorial Day - 5/30/2016.
Please go here for more info.

Now Offering Over 85,203 Antibodies & 34,301 Antigens!

US

Transcription Factor Antibodies

Transcription factors are proteins that regulate gene expression by binding to DNA via one or more DNA-binding domains. This binding is achieved via a combination of electrostatic and van der waals forces and can occur at many closely-related sequences flanking different genes. Once bound to DNA directly or as part of a complex, they can promote or inhibit RNA polymerase recruitment, thereby acting as activators or repressors, respectively. Alternatively, transcription factors can act to recruit coactivators and corepressors or to catalyze histone acetylation and deacetylation. Transcription factors can function downstream of signaling cascades triggered by biological or environmental (ex. hypoxia, hyperthermia) stimuli to alter the expression of target genes. Ligand binding is necessary to activate some transcription factors as this can cause nuclear translocation and changes in the binding affinities for DNA and cofactors. During development, various stimuli can cause transcription factors to up- or down-regulate expression of specific genes at distinct time points to ensure proper development. Transcription factors can function as oncogenes or tumor suppressors and have thus been linked to various cancers. Accordingly, some therapeutic approaches in cancer therapy involve targeting transcription factor families[1].

1. Darnell JE Jr. 2002. Transcription factors as targets for cancer therapy. Nat Rev Cancer. Oct;2(10):740-9.

Transcription Factor Antibodies Top 20 Showcase

View the entire product list by clicking here.

Transcription Factors are involved in transcriptional regulation in the form of up regulation or down regulation acting as either repressors or activators of transcription. We have manufactured more than 3000 antibody products covering almost every known human and mouse transcription factors.

Page of 141

Showing 451 - 480 of 4220
  • TRIAL 
    TSG101 Antibody - N-terminal region (ARP33463_P050) in Human Thymus tumor using Western Blot
    TSG101 Antibody - N-terminal region (ARP33463_P050) in human heart using Immunohistochemistry

    TSG101 Antibody - N-terminal region (ARP33463_P050)

    Protein Name:Tumor susceptibility gene 101 protein
    Catalog #:ARP33463_P050
    Type: pAb
    Reacts with: Cow, Dog, Goat, Guinea Pig, Horse, Human, Mouse, Rabbit, Rat, Zebrafish
    Application: WB, IHC
    Product Size: 100 ul
    Price (USD): $289.00
  • TRIAL 
    S100a5 antibody - middle region (ARP56530_P050) in Mouse Small Intestine using Western Blot

    S100a5 antibody - middle region (ARP56530_P050)

    Protein Name:S100 calcium binding protein A5 EMBL AAI17109.1
    Catalog #:ARP56530_P050
    Type: pAb
    Reacts with: Cow, Dog, Guinea Pig, Horse, Human, Mouse, Pig, Rabbit, Rat
    Application: WB
    Product Size: 100 ul
    Price (USD): $289.00
  • TRIAL 
    ZSCAN22 Antibody - N-terminal region (ARP33529_P050) in Human Breast Tumor using Western Blot

    ZSCAN22 Antibody - N-terminal region (ARP33529_P050)

    Protein Name:Zinc finger and SCAN domain-containing protein 22
    Catalog #:ARP33529_P050
    Type: pAb
    Reacts with: Cow, Dog, Guinea Pig, Horse, Human, Mouse, Rabbit, Rat
    Application: WB
    Product Size: 100 ul
    Price (USD): $289.00
  • TRIAL 
    ATG13 antibody - N-terminal region (ARP64384_P050) in Human PANC1 using Western Blot

    ATG13 antibody - N-terminal region (ARP64384_P050)

    Protein Name:Autophagy-related protein 13
    Catalog #:ARP64384_P050
    Type: pAb
    Reacts with: Cow, Dog, Guinea Pig, Horse, Human, Mouse, Rabbit, Rat
    Application: WB
    Product Size: 100 ul
    Price (USD): $289.00
  • TRIAL 
    Dlx6 antibody - C-terminal region (ARP35763_P050) in Rat Muscle using Western Blot

    Dlx6 antibody - C-terminal region (ARP35763_P050)

    Protein Name:
    Catalog #:ARP35763_P050
    Type: pAb
    Reacts with: Cow, Dog, Guinea Pig, Horse, Human, Mouse, Rabbit, Rat, Zebrafish
    Application: WB
    Product Size: 100 ul
    Price (USD): $289.00
  • TRIAL 
    DHX38 antibody - middle region (ARP36412_P050) in Human OVCAR-3 using Western Blot

    DHX38 antibody - middle region (ARP36412_P050)

    Protein Name:Pre-mRNA-splicing factor ATP-dependent RNA helicase PRP16
    Catalog #:ARP36412_P050
    Type: pAb
    Reacts with: Cow, Dog, Guinea Pig, Horse, Human, Mouse, Rabbit, Rat, Zebrafish
    Application: WB
    Product Size: 100 ul
    Price (USD): $289.00
  • TRIAL 
    Ovol1 Antibody - C-terminal region (ARP37272_P050) in Rat Pancreas using Western Blot

    Ovol1 Antibody - C-terminal region (ARP37272_P050)

    Protein Name:Ovo-like 1(Drosophila) (Predicted) EMBL EDM12506.1
    Catalog #:ARP37272_P050
    Type: pAb
    Reacts with: Cow, Dog, Goat, Guinea Pig, Horse, Human, Mouse, Rabbit, Rat
    Application: WB
    Product Size: 100 ul
    Price (USD): $289.00
  • TRIAL 
    SCG5 antibody - N-terminal region (ARP63847_P050) in Human Jurkat using Western Blot

    SCG5 antibody - N-terminal region (ARP63847_P050)

    Protein Name:Neuroendocrine protein 7B2
    Catalog #:ARP63847_P050
    Type: pAb
    Reacts with: Cow, Dog, Guinea Pig, Horse, Human, Mouse, Rabbit, Rat, Zebrafish
    Application: WB
    Product Size: 100 ul
    Price (USD): $289.00
  • TRIAL 
    Terf2ip antibody - middle region (ARP57301_P050) in Mouse Pancreas using Western Blot

    Terf2ip antibody - middle region (ARP57301_P050)

    Protein Name:Telomeric repeat-binding factor 2-interacting protein 1
    Catalog #:ARP57301_P050
    Type: pAb
    Reacts with: Cow, Dog, Guinea Pig, Horse, Human, Mouse, Rabbit, Rat
    Application: WB
    Product Size: 100 ul
    Price (USD): $289.00

Page of 141

Showing 451 - 480 of 4220