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Now Offering Over 85,203 Antibodies & 34,301 Antigens!

Transcription Factor Antibodies

Transcription factors are proteins that regulate gene expression by binding to DNA via one or more DNA-binding domains. This binding is achieved via a combination of electrostatic and van der waals forces and can occur at many closely-related sequences flanking different genes. Once bound to DNA directly or as part of a complex, they can promote or inhibit RNA polymerase recruitment, thereby acting as activators or repressors, respectively. Alternatively, transcription factors can act to recruit coactivators and corepressors or to catalyze histone acetylation and deacetylation. Transcription factors can function downstream of signaling cascades triggered by biological or environmental (ex. hypoxia, hyperthermia) stimuli to alter the expression of target genes. Ligand binding is necessary to activate some transcription factors as this can cause nuclear translocation and changes in the binding affinities for DNA and cofactors. During development, various stimuli can cause transcription factors to up- or down-regulate expression of specific genes at distinct time points to ensure proper development. Transcription factors can function as oncogenes or tumor suppressors and have thus been linked to various cancers. Accordingly, some therapeutic approaches in cancer therapy involve targeting transcription factor families[1].

1. Darnell JE Jr. 2002. Transcription factors as targets for cancer therapy. Nat Rev Cancer. Oct;2(10):740-9.

Transcription Factor Antibodies Top 20 Showcase

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Transcription Factors are involved in transcriptional regulation in the form of up regulation or down regulation acting as either repressors or activators of transcription. We have manufactured more than 3000 antibody products covering almost every known human and mouse transcription factors.

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Showing 451 - 480 of 3976
  Type Catalog # Product Product Images Price (USD)
  pAb ARP33528_P050 ZNF232 Antibody - N-terminal region (ARP33528_P050)
Reacts with
Pig, Human, Mouse, Horse, Rat, Guinea pig, Dog, Bovine, Rabbit
Application
WB
$289.00
  pAb ARP72092_P050 ZNF772 Antibody - N-terminal region (ARP72092_P050)
Reacts with
Human, Horse, Rat, Pig, Zebrafish, Rabbit, Dog, Bovine, Mouse, Guinea pig
Application
WB
$289.00
  pAb ARP51732_P050 EBF4 antibody - C-terminal region (ARP51732_P050)
Reacts with
Human, Bovine, Dog, Pig, Horse, Rabbit, Rat, Mouse, Guinea pig
Application
WB
$289.00
  pAb ARP37272_P050 Ovol1 Antibody - C-terminal region (ARP37272_P050)
Reacts with
Bovine, Human, Rat, Dog, Pig, Horse, Goat, Rabbit, Guinea pig, Mouse
Application
WB
$289.00
  pAb ARP64032_P050 RAP2A antibody - C-terminal region (ARP64032_P050)
Reacts with
Human, Sheep, Bovine, Horse, Mouse, Rat, Dog, Rabbit, Guinea pig, Zebrafish
Application
WB
$289.00
  pAb ARP37401_P050 Taf7l Antibody - C-terminal region (ARP37401_P050)
Reacts with
Mouse, Rat, Bovine, Pig
Application
WB
$289.00
  pAb ARP64050_P050 PROKR2 antibody - C-terminal region (ARP64050_P050)
Reacts with
Human, Mouse, Horse, Rabbit, Rat, Dog, Bovine, Guinea pig
Application
WB
$289.00
  pAb ARP32145_P050 Rnf166 antibody - middle region (ARP32145_P050)
Reacts with
Mouse, Human, Horse, Rat, Guinea pig, Dog, Bovine, Zebrafish
Application
WB
$289.00
  pAb ARP38529_P050 HDAC1 Antibody - N-terminal region (ARP38529_P050)
Reacts with
Mouse, Human, Rat, Dog, Pig, Bovine, Zebrafish, Horse, Rabbit, Guinea pig
Application
WB
$289.00
  pAb ARP32693_P050 MBD1 antibody - C-terminal region (ARP32693_P050)
Reacts with
Human, Dog, Pig, Horse, Rabbit, Rat, Guinea pig, Bovine
Application
WB
$289.00
  pAb ARP31879_P050 Aff4 Antibody - middle region (ARP31879_P050)
Reacts with
Rat, Guinea pig, Human, Horse, Bovine, Rabbit, Mouse, Dog
Application
WB
$289.00
  pAb ARP50361_P050 ZNF658B Antibody - middle region (ARP50361_P050)
Reacts with
Human, Horse, Pig, Rat, Zebrafish, Bovine, Guinea pig, Mouse, Rabbit, Yeast, Dog
Application
WB
$289.00
  pAb ARP30278_P050 BAD antibody - middle region (ARP30278_P050)
Reacts with
Human, Mouse, Bovine, Horse, Rabbit, Rat, Guinea pig
Application
WB
$289.00
  pAb ARP32007_P050 SMAD6 Antibody - N-terminal region (ARP32007_P050)
Reacts with
Rat, Human, Mouse, Bovine, Pig, Guinea pig
Application
WB
$289.00
  pAb ARP70505_P050 GREB1 Antibody - N-terminal region (ARP70505_P050)
Reacts with
Mouse, Bovine, Dog, Rat, Pig, Horse, Human, Rabbit, Guinea pig, Zebrafish
Application
WB
$289.00
  pAb ARP62688_P050 MRPL3 antibody - N-terminal region (ARP62688_P050)
Reacts with
Human, Rabbit, Rat, Guinea pig, Dog, Horse, Bovine, Mouse
Application
WB
$289.00
  pAb ARP36265_P050 ZNF735 Antibody - middle region (ARP36265_P050)
Reacts with
Human
Application
WB
$289.00
  pAb ARP34444_P050 Trim35 Antibody - middle region (ARP34444_P050)
Reacts with
Dog, Bovine, Horse, Rabbit, Human, Pig, Rat, Guinea pig, Mouse
Application
WB
$289.00
  pAb ARP61864_P050 Nup160 antibody - C-terminal region (ARP61864_P050)
Reacts with
Bovine, Rat, Dog, Pig, Human, Guinea pig, Mouse, Horse, Rabbit
Application
WB
$289.00
  pAb ARP64603_P050 DMGDH antibody - C-terminal region (ARP64603_P050)
Reacts with
Human, Pig, Rat, Horse
Application
WB
$289.00
  pAb ARP32884_P050 Trit1 antibody - N-terminal region (ARP32884_P050)
Reacts with
Bovine, Human, Rat, Dog, Horse, Rabbit, Guinea pig, Mouse
Application
WB
$289.00
  pAb ARP39702_P050 IKZF3 Antibody - middle region (ARP39702_P050)
Reacts with
Human, Bovine, Rat, Dog, Pig, Horse, Rabbit, Guinea pig, Mouse, Yeast
Application
WB
$289.00
  pAb ARP40457_P050 Srp54a antibody - C-terminal region (ARP40457_P050)
Reacts with
Horse, Human, Pig, Rabbit, Rat, Guinea pig, Mouse, Dog, Bovine, Zebrafish, Sheep
Application
WB
$289.00
  pAb ARP30019_P050 MINA Antibody - C-terminal region (ARP30019_P050)
Reacts with
Human, Rabbit, Rat, Dog, Pig
Application
WB
$289.00
  pAb ARP58078_P050 SLC18A1 Antibody - N-terminal region (ARP58078_P050)
Reacts with
Human, Bovine, Pig, Dog, Horse
Application
WB
$289.00
  pAb ARP43374_P050 Trim7 antibody - N-terminal region (ARP43374_P050)
Reacts with
Human, Mouse, Rat, Bovine, Rabbit, Dog
Application
WB
$289.00
  pAb ARP33686_P050 DKFZp686M216 Antibody - N-terminal region (ARP33686_P050)
Reacts with
Dog, Zebrafish, Pig, Horse, Rabbit, Bovine, Rat, Guinea pig, Mouse, Human, Sheep
Application
WB
$289.00
  pAb ARP31582_P050 ZNF586 Antibody - middle region (ARP31582_P050)
Reacts with
Human, Dog, Horse, Bovine, Pig, Rabbit, Guinea pig, Rat, Mouse
Application
WB
$289.00
  pAb ARP39061_P050 Hoxc11 antibody - N-terminal region (ARP39061_P050)
Reacts with
Rat, Horse, Rabbit, Guinea pig, Human, Mouse, Dog, Bovine, Zebrafish
Application
WB
$289.00
  pAb ARP32430_T100 BHLHB5 antibody - N-terminal region (ARP32430_T100)
Reacts with
Human, Bovine, Zebrafish, Pig, Rabbit, Guinea pig, Rat, Mouse
Application
WB
$229.00

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Showing 451 - 480 of 3976