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Now Offering Over 85,203 Antibodies & 34,301 Antigens!

Transcription Factor Antibodies

Transcription factors are proteins that regulate gene expression by binding to DNA via one or more DNA-binding domains. This binding is achieved via a combination of electrostatic and van der waals forces and can occur at many closely-related sequences flanking different genes. Once bound to DNA directly or as part of a complex, they can promote or inhibit RNA polymerase recruitment, thereby acting as activators or repressors, respectively. Alternatively, transcription factors can act to recruit coactivators and corepressors or to catalyze histone acetylation and deacetylation. Transcription factors can function downstream of signaling cascades triggered by biological or environmental (ex. hypoxia, hyperthermia) stimuli to alter the expression of target genes. Ligand binding is necessary to activate some transcription factors as this can cause nuclear translocation and changes in the binding affinities for DNA and cofactors. During development, various stimuli can cause transcription factors to up- or down-regulate expression of specific genes at distinct time points to ensure proper development. Transcription factors can function as oncogenes or tumor suppressors and have thus been linked to various cancers. Accordingly, some therapeutic approaches in cancer therapy involve targeting transcription factor families[1].

1. Darnell JE Jr. 2002. Transcription factors as targets for cancer therapy. Nat Rev Cancer. Oct;2(10):740-9.

Transcription Factor Antibodies Top 20 Showcase

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Transcription Factors are involved in transcriptional regulation in the form of up regulation or down regulation acting as either repressors or activators of transcription. We have manufactured more than 3000 antibody products covering almost every known human and mouse transcription factors.

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Showing 451 - 480 of 3998
  Type Catalog # Product Product Images Price (USD)
  pAb ARP50343_P050 ZNF134 Antibody - middle region (ARP50343_P050)
Reacts with
Human, Dog, Rabbit, Bovine, Rat, Mouse, Pig, Horse, Goat, Guinea pig
Application
WB
$289.00
  pAb ARP64835_P050 NADK antibody - C-terminal region (ARP64835_P050)
Reacts with
Mouse, Human, Dog, Bovine, Horse, Rat, Rabbit, Guinea pig, Zebrafish
Application
WB
$289.00
  pAb ARP61955_P050 HMGN3 antibody - middle region (ARP61955_P050)
Reacts with
Dog, Horse, Rabbit, Guinea pig, Rat, Human, Mouse, Bovine
Application
WB
$289.00
  pAb ARP69918_P050 ZNF506 Antibody - C-terminal region (ARP69918_P050)
Reacts with
Mouse, Human, Zebrafish, Horse, Pig, Rat, Dog, Bovine
Application
WB
$289.00
  pAb ARP40415_P050 SRGN antibody - N-terminal region (ARP40415_P050)
Reacts with
Human, Rat, Mouse, Rabbit
Application
WB
$289.00
  pAb ARP72751_P050 GCM2 Antibody - N-terminal region (ARP72751_P050)
Reacts with
Human, Bovine, Dog, Horse, Rabbit, Rat, Guinea pig, Zebrafish, Mouse
Application
WB
$289.00
  pAb ARP30932_P050 LYL1 Antibody - C-terminal region (ARP30932_P050)
Reacts with
Pig, Human
Application
WB
$289.00
  pAb ARP54337_P050 Igfbp5 antibody - middle region (ARP54337_P050)
Reacts with
Sheep, Human, Pig, Dog, Goat, Rabbit, Rat, Bovine, Mouse, Horse, Guinea pig
Application
WB
$289.00
  pAb ARP34734_P050 GREB1 Antibody - N-terminal region (ARP34734_P050)
Reacts with
Bovine, Dog, Horse, Rabbit, Human, Mouse, Pig, Zebrafish, Rat, Guinea pig
Application
WB
$289.00
  pAb ARP39224_P050 2700060E02Rik antibody - C-terminal region (ARP39224_P050)
Reacts with
Dog, Zebrafish, Pig, Horse, Rabbit, Rat, Guinea pig, Mouse, Bovine, Human, Yeast
Application
WB
$289.00
  pAb ARP56530_P050 S100a5 antibody - middle region (ARP56530_P050)
Reacts with
Bovine, Dog, Pig, Horse, Rabbit, Human, Rat, Mouse, Guinea pig
Application
WB
$289.00
  pAb ARP37786_P050 ZNF773 Antibody - middle region (ARP37786_P050)
Reacts with
Human
Application
WB
$289.00
  pAb ARP39935_P050 NPAS3 Antibody - middle region (ARP39935_P050)
Reacts with
Bovine, Pig, Mouse, Human, Rat, Zebrafish, Dog, Horse, Rabbit, Goat, Guinea pig
Application
WB
$289.00
  pAb ARP60640_P050 CD99L2 antibody - middle region (ARP60640_P050)
Reacts with
Human, Dog, Pig, Horse, Rabbit, Bovine
Application
WB
$289.00
  pAb ARP30673_P050 CHRNA6 antibody - N-terminal region (ARP30673_P050)
Reacts with
Human, Dog, Pig, Bovine, Horse, Rabbit, Rat, Mouse
Application
WB
$289.00
  pAb ARP32653_P050 FOXN2 antibody - middle region (ARP32653_P050)
Reacts with
Human, Bovine, Mouse, Rat, Guinea pig, Dog, Rabbit, Horse
Application
WB
$289.00
  pAb ARP30713_T100 HTR1E Antibody - N-terminal region (ARP30713_T100)
Reacts with
Human, Pig, Bovine, Horse, Dog
Application
WB
$229.00
  pAb ARP39075_P050 Brd4 Antibody - N-terminal region (ARP39075_P050)
Reacts with
Mouse, Rabbit, Rat, Guinea pig, Human, Dog, Bovine, Horse
Application
WB
$289.00
  pAb ARP43148_P050 Rnf11l antibody - C-terminal region (ARP43148_P050)
Reacts with
Rat, Bovine, Dog, Pig, Horse, Rabbit, Guinea pig, Mouse, Human, Zebrafish
Application
WB
$289.00
  pAb ARP33008_P050 Prrx2 Antibody - middle region (ARP33008_P050)
Reacts with
Dog, Human, Rat, Bovine, Pig, Horse, Rabbit, Guinea pig, Mouse
Application
WB
$289.00
  pAb ARP52340_P050 PSORS1C1 antibody - N-terminal region (ARP52340_P050)
Reacts with
Human
Application
WB
$289.00
  pAb ARP37096_P050 Msx3 Antibody - C-terminal region (ARP37096_P050)
Reacts with
Mouse, Rat
Application
WB
$289.00
  pAb ARP38628_P050 MED6 Antibody - C-terminal region (ARP38628_P050)
Reacts with
Human, Horse, Rabbit, Dog, Rat, Bovine, Mouse
Application
IHC, WB
$289.00
  pAb ARP63726_P050 FGF19 antibody - C-terminal region (ARP63726_P050)
Reacts with
Human
Application
WB
$289.00
  pAb ARP43221_P050 Bfar antibody - middle region (ARP43221_P050)
Reacts with
Human, Mouse, Horse, Rat, Guinea pig, Dog, Rabbit, Bovine
Application
WB
$289.00
  pAb ARP50658_P050 ZNF625 Antibody - middle region (ARP50658_P050)
Reacts with
Human, Horse
Application
WB
$289.00
  pAb ARP45620_P050 NR5A1 antibody - middle region (ARP45620_P050)
Reacts with
Human, Rat, Dog, Horse, Guinea pig, Mouse, Bovine, Sheep
Application
WB
$289.00
  pAb ARP69904_P050 ZBTB34 Antibody - C-terminal region (ARP69904_P050)
Reacts with
Horse, Pig, Human, Mouse, Dog, Bovine, Rat, Guinea pig, Rabbit
Application
WB
$289.00
  pAb ARP65625_P050 YY2 Antibody - C-terminal region (ARP65625_P050)
Reacts with
Human
Application
WB
$289.00
  pAb ARP53022_P050 ALS2CR11 antibody - N-terminal region (ARP53022_P050)
Reacts with
Human
Application
WB
$289.00

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Showing 451 - 480 of 3998