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Now Offering Over 85,203 Antibodies & 34,301 Antigens!

Transcription Factor Antibodies

Transcription factors are proteins that regulate gene expression by binding to DNA via one or more DNA-binding domains. This binding is achieved via a combination of electrostatic and van der waals forces and can occur at many closely-related sequences flanking different genes. Once bound to DNA directly or as part of a complex, they can promote or inhibit RNA polymerase recruitment, thereby acting as activators or repressors, respectively. Alternatively, transcription factors can act to recruit coactivators and corepressors or to catalyze histone acetylation and deacetylation. Transcription factors can function downstream of signaling cascades triggered by biological or environmental (ex. hypoxia, hyperthermia) stimuli to alter the expression of target genes. Ligand binding is necessary to activate some transcription factors as this can cause nuclear translocation and changes in the binding affinities for DNA and cofactors. During development, various stimuli can cause transcription factors to up- or down-regulate expression of specific genes at distinct time points to ensure proper development. Transcription factors can function as oncogenes or tumor suppressors and have thus been linked to various cancers. Accordingly, some therapeutic approaches in cancer therapy involve targeting transcription factor families[1].

1. Darnell JE Jr. 2002. Transcription factors as targets for cancer therapy. Nat Rev Cancer. Oct;2(10):740-9.

Transcription Factor Antibodies Top 20 Showcase

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Transcription Factors are involved in transcriptional regulation in the form of up regulation or down regulation acting as either repressors or activators of transcription. We have manufactured more than 3000 antibody products covering almost every known human and mouse transcription factors.

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Showing 451 - 480 of 4022
  Type Catalog # Product Product Images Price (USD)
  pAb ARP63896_P050 GDAP1 antibody - C-terminal region (ARP63896_P050)
Reacts with
Human, Bovine, Dog, Pig, Horse, Rabbit, Rat, Guinea pig, Mouse, Zebrafish
Application
WB
$289.00
  pAb ARP50361_P050 ZNF658B Antibody - middle region (ARP50361_P050)
Reacts with
Human, Horse, Pig, Rat, Zebrafish, Bovine, Guinea pig, Mouse, Rabbit, Yeast, Dog
Application
WB
$289.00
  pAb ARP66510_P050 Akirin2 Antibody - C-terminal region (ARP66510_P050)
Reacts with
Bovine, Mouse, Dog, Pig, Horse, Rabbit, Sheep, Guinea pig, Rat, Human, Zebrafish
Application
WB
$289.00
  pAb ARP50052_P050 Tmem117 antibody - C-terminal region (ARP50052_P050)
Reacts with
Bovine, Human, Rat, Dog, Pig, Horse, Rabbit, Guinea pig, Mouse, Zebrafish
Application
WB
$289.00
  pAb ARP32871_P050 Nr0b1 Antibody - C-terminal region (ARP32871_P050)
Reacts with
Human, Pig, Rat, Rabbit, Bovine, Guinea pig, Mouse, Horse, Dog
Application
WB
$289.00
  pAb ARP72231_P050 FOXD4L1 Antibody - N-terminal region (ARP72231_P050)
Reacts with
Human, Pig, Rabbit, Bovine
Application
WB
$289.00
  pAb ARP31300_P050 ISL1 Antibody - C-terminal region (ARP31300_P050)
Reacts with
Mouse, Bovine, Human, Dog, Pig, Horse, Rabbit, Rat, Guinea pig, Sheep, Zebrafish
Application
WB
$289.00
  pAb ARP62393_P050 LY6G5B antibody - N-terminal region (ARP62393_P050)
Reacts with
Human, Dog, Pig, Horse
Application
WB
$289.00
  pAb ARP35732_P050 ILF2 Antibody - N-terminal region (ARP35732_P050)
Reacts with
Rat, Human, Dog, Bovine, Horse, Rabbit, Guinea pig, Mouse, Zebrafish
Application
WB
$289.00
  pAb ARP56946_P050 Rasl12 antibody - N-terminal region (ARP56946_P050)
Reacts with
Human, Rat, Mouse, Bovine, Pig, Horse, Rabbit, Guinea pig
Application
WB
$289.00
  pAb ARP39939_P050 ZNF772 Antibody - N-terminal region (ARP39939_P050)
Reacts with
Human, Rabbit, Bovine, Pig, Horse, Rat, Dog, Mouse
Application
WB
$289.00
  pAb ARP37896_P050 Nr2c1 Antibody - middle region (ARP37896_P050)
Reacts with
Rat, Human, Mouse, Dog, Horse, Rabbit
Application
WB
$289.00
  pAb ARP64386_P050 CA13 antibody - N-terminal region (ARP64386_P050)
Reacts with
Bovine, Rat, Pig, Horse, Rabbit, Dog, Human, Mouse, Guinea pig
Application
WB
$289.00
  pAb ARP57974_P050 EYA3 Antibody - middle region (ARP57974_P050)
Reacts with
Human, Guinea pig, Sheep, Bovine, Horse, Rat, Rabbit, Mouse
Application
WB
$289.00
  pAb ARP33286_T100 SHOX2 antibody - middle region (ARP33286_T100)
Reacts with
Human, Bovine, Dog, Zebrafish, Horse, Mouse, Rat, Guinea pig, Rabbit
Application
WB
$229.00
  pAb ARP36247_P050 Olig3 antibody - N-terminal region (ARP36247_P050)
Reacts with
Rat, Dog, Pig, Rabbit, Bovine, Guinea pig, Mouse, Human, Horse
Application
WB
$289.00
  pAb ARP32663_P050 ZNF589 Antibody - C-terminal region (ARP32663_P050)
Reacts with
Dog, Pig, Horse, Rabbit, Bovine, Rat, Guinea pig, Human, Mouse
Application
WB
$289.00
  pAb ARP36414_P050 SNRNP200 antibody - N-terminal region (ARP36414_P050)
Reacts with
Human, Bovine, Rat, Pig, Horse, Rabbit, Guinea pig, Mouse, Zebrafish
Application
WB
$289.00
  pAb ARP31186_P050 Gabpa Antibody - N-terminal region (ARP31186_P050)
Reacts with
Human, Rat, Dog, Horse, Rabbit, Guinea pig, Mouse, Bovine
Application
WB
$289.00
  pAb ARP47386_P050 Tapbpl antibody - N-terminal region (ARP47386_P050)
Reacts with
Rat, Guinea pig, Human, Mouse, Dog, Horse, Rabbit, Bovine
Application
WB
$289.00
  pAb ARP33223_P050 RFX4 Antibody - N-terminal region (ARP33223_P050)
Reacts with
Human, Dog, Bovine, Pig, Horse, Rabbit, Zebrafish, Rat, Guinea pig, Mouse
Application
WB
$289.00
  pAb ARP42659_P050 Nrbf2 antibody - N-terminal region (ARP42659_P050)
Reacts with
Mouse, Horse, Rabbit, Rat, Dog, Bovine, Human, Zebrafish
Application
WB
$289.00
  pAb ARP33463_P050 TSG101 Antibody - N-terminal region (ARP33463_P050)
Reacts with
Bovine, Dog, Human, Goat, Rabbit, Rat, Pig, Guinea pig, Mouse, Horse, Zebrafish
Application
WB
$289.00
  pAb ARP32443_T100 LHX3 antibody - middle region (ARP32443_T100)
Reacts with
Human, Rat, Pig, Bovine, Zebrafish, Guinea pig, Mouse, Dog, Horse
Application
WB
$229.00
  pAb ARP63640_P050 CDC73 antibody - C-terminal region (ARP63640_P050)
Reacts with
Dog, Bovine, Rat, Horse, Rabbit, Human, Mouse, Zebrafish
Application
WB
$289.00
  pAb ARP38998_P050 SETDB1 Antibody - N-terminal region (ARP38998_P050)
Reacts with
Human, Dog, Horse, Bovine, Rat, Guinea pig, Rabbit
Application
WB
$289.00
  pAb ARP37194_P050 Uncx Antibody - N-terminal region (ARP37194_P050)
Reacts with
Bovine, Rat, Mouse, Human, Dog, Pig, Zebrafish
Application
WB
$289.00
  pAb ARP69005_P050 ZMYND15 Antibody - N-terminal region (ARP69005_P050)
Reacts with
Human, Dog, Rabbit, Rat, Pig
Application
WB
$289.00
  pAb ARP31097_P050 HSF2 antibody - N-terminal region (ARP31097_P050)
Reacts with
Bovine, Dog, Pig, Horse, Rabbit, Rat, Guinea pig, Human, Zebrafish, Mouse
Application
WB
$289.00
  pAb ARP30108_P050 Tsc22d4 Antibody - N-terminal region (ARP30108_P050)
Reacts with
Rat, Human, Dog, Rabbit, Guinea pig, Bovine, Mouse, Horse
Application
WB
$289.00

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Showing 451 - 480 of 4022