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Now Offering Over 85,203 Antibodies & 34,301 Antigens!

Transcription Factor Antibodies

Transcription factors are proteins that regulate gene expression by binding to DNA via one or more DNA-binding domains. This binding is achieved via a combination of electrostatic and van der waals forces and can occur at many closely-related sequences flanking different genes. Once bound to DNA directly or as part of a complex, they can promote or inhibit RNA polymerase recruitment, thereby acting as activators or repressors, respectively. Alternatively, transcription factors can act to recruit coactivators and corepressors or to catalyze histone acetylation and deacetylation. Transcription factors can function downstream of signaling cascades triggered by biological or environmental (ex. hypoxia, hyperthermia) stimuli to alter the expression of target genes. Ligand binding is necessary to activate some transcription factors as this can cause nuclear translocation and changes in the binding affinities for DNA and cofactors. During development, various stimuli can cause transcription factors to up- or down-regulate expression of specific genes at distinct time points to ensure proper development. Transcription factors can function as oncogenes or tumor suppressors and have thus been linked to various cancers. Accordingly, some therapeutic approaches in cancer therapy involve targeting transcription factor families[1].

1. Darnell JE Jr. 2002. Transcription factors as targets for cancer therapy. Nat Rev Cancer. Oct;2(10):740-9.

Transcription Factor Antibodies Top 20 Showcase

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Transcription Factors are involved in transcriptional regulation in the form of up regulation or down regulation acting as either repressors or activators of transcription. We have manufactured more than 3000 antibody products covering almost every known human and mouse transcription factors.

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Showing 451 - 480 of 4061
  Type Catalog # Product Product Images Price (USD)
  pAb ARP39531_P050 NR1I2 Antibody - N-terminal region (ARP39531_P050)
Reacts with
Human
Application
WB
$289.00
  pAb ARP42369_P050 PPP2R3B antibody - N-terminal region (ARP42369_P050)
Reacts with
Human
Application
WB
$289.00
  pAb ARP36844_P050 DKFZp686H0575 Antibody - C-terminal region (ARP36844_P050)
Reacts with
Mouse, Rat, Human, Dog, Horse
Application
WB
$289.00
  pAb ARP53574_P050 AURKA Antibody - middle region (ARP53574_P050)
Reacts with
Human, Bovine, Dog, Horse, Mouse, Rabbit, Rat, Guinea pig, Zebrafish, Sheep
Application
WB
$289.00
  pAb ARP64117_P050 MYOT antibody - C-terminal region (ARP64117_P050)
Reacts with
Mouse, Human, Rat, Dog, Bovine, Pig, Horse, Rabbit, Guinea pig
Application
WB
$289.00
  pAb ARP43014_P050 Ube2g1 antibody - N-terminal region (ARP43014_P050)
Reacts with
Bovine, Pig, Horse, Rabbit, Rat, Guinea pig, Dog, Human, Mouse, Zebrafish, Yeast
Application
WB
$289.00
  pAb ARP50985_P050 ZNF679 Antibody - N-terminal region (ARP50985_P050)
Reacts with
Human
Application
WB
$289.00
  pAb ARP35063_P050 Glra3 antibody - middle region (ARP35063_P050)
Reacts with
Human, Rat, Dog, Pig, Horse, Rabbit, Bovine, Guinea pig, Mouse, Zebrafish
Application
WB
$289.00
  pAb ARP51645_P050 ZNF73 Antibody - N-terminal region (ARP51645_P050)
Reacts with
Mouse, Human, Rabbit, Rat
Application
WB
$289.00
  pAb ARP31165_P050 Atf7 antibody - C-terminal region (ARP31165_P050)
Reacts with
Rat, Human, Dog, Bovine, Pig, Horse, Rabbit, Guinea pig, Mouse
Application
WB
$289.00
  pAb ARP38427_P050 ZNF284 Antibody - N-terminal region (ARP38427_P050)
Reacts with
Bovine, Pig, Rat, Dog, Human, Mouse, Horse
Application
WB
$289.00
  pAb ARP63579_P050 MSR1 antibody - N-terminal region (ARP63579_P050)
Reacts with
Human, Dog, Horse, Pig, Bovine
Application
WB
$289.00
  pAb ARP34882_P050 ZMYM6 Antibody - N-terminal region (ARP34882_P050)
Reacts with
Human
Application
WB
$289.00
  pAb ARP47578_P050 ZNF397 Antibody - middle region (ARP47578_P050)
Reacts with
Human, Bovine, Pig, Horse, Rabbit, Rat, Guinea pig, Dog, Mouse, Goat
Application
WB
$289.00
  pAb ARP62718_P050 Sqrdl antibody - C-terminal region (ARP62718_P050)
Reacts with
Rat, Human, Pig, Horse, Rabbit, Bovine, Dog, Guinea pig, Mouse, Zebrafish
Application
WB
$289.00
  pAb ARP60528_P050 Vps25 Antibody - C-terminal region (ARP60528_P050)
Reacts with
Mouse, Dog, Human, Rat, Bovine, Guinea pig
Application
WB
$289.00
  pAb ARP64783_P050 SBF1 antibody - C-terminal region (ARP64783_P050)
Reacts with
Human, Bovine, Rat, Pig, Mouse, Dog, Horse, Guinea pig
Application
WB
$289.00
  pAb ARP39917_P050 Zfp759 antibody - N-terminal region (ARP39917_P050)
Reacts with
Pig, Horse, Dog, Human, Mouse, Bovine, Rat, Rabbit
Application
WB
$289.00
  pAb ARP72147_P050 SOHLH2 Antibody - N-terminal region (ARP72147_P050)
Reacts with
Human, Dog, Rat, Guinea pig
Application
WB
$289.00
  pAb ARP44636_P050 AGPAT2 antibody - C-terminal region (ARP44636_P050)
Reacts with
Human, Dog, Yeast, Bovine, Horse
Application
WB
$289.00
  pAb ARP37438_P050 Foxp3 Antibody - N-terminal region (ARP37438_P050)
Reacts with
Rat, Mouse, Rabbit
Application
WB
$289.00
  pAb ARP46559_P050 Ndufb8 antibody - C-terminal region (ARP46559_P050)
Reacts with
Bovine, Rat, Sheep, Dog, Horse, Goat, Rabbit, Guinea pig, Human, Zebrafish, Mouse
Application
WB
$289.00
  pAb ARP33463_P050 TSG101 Antibody - N-terminal region (ARP33463_P050)
Reacts with
Bovine, Dog, Human, Goat, Rabbit, Rat, Pig, Guinea pig, Mouse, Horse, Zebrafish
Application
WB
$289.00
  pAb ARP31541_P050 4930567H17Rik antibody - middle region (ARP31541_P050)
Reacts with
Mouse, Human, Yeast, Rat, Zebrafish, Rabbit, Pig, Horse, Bovine, Dog
Application
WB
$289.00
  pAb ARP37061_P050 Hoxa1 Antibody - C-terminal region (ARP37061_P050)
Reacts with
Horse, Zebrafish, Rabbit, Mouse, Bovine, Dog, Pig, Rat, Guinea pig, Human
Application
WB
$289.00
  pAb ARP56521_P050 Rfc1 Antibody - C-terminal region (ARP56521_P050)
Reacts with
Rat, Rabbit, Mouse, Guinea pig, Human, Dog, Horse
Application
WB
$289.00
  pAb ARP48979_P050 ESCO1 antibody - N-terminal region (ARP48979_P050)
Reacts with
Human, Dog, Rat, Horse, Bovine, Pig
Application
WB
$289.00
  pAb ARP30331_P050 CDK2 antibody - middle region (ARP30331_P050)
Reacts with
Bovine, Goat, Guinea pig, Human, Mouse, Rabbit, Rat, Sheep, Zebrafish
Application
WB
$289.00
  pAb ARP51120_P050 DUX4 Antibody - middle region (ARP51120_P050)
Reacts with
Human
Application
WB
$289.00
  pAb ARP32320_T100 HNF1B antibody - N-terminal region (ARP32320_T100)
Reacts with
Rat, Zebrafish, Human, Dog, Bovine, Horse, Guinea pig, Mouse
Application
WB
$229.00

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Showing 451 - 480 of 4061