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Now Offering Over 85,203 Antibodies & 34,301 Antigens!

Transcription Factor Antibodies

Transcription factors are proteins that regulate gene expression by binding to DNA via one or more DNA-binding domains. This binding is achieved via a combination of electrostatic and van der waals forces and can occur at many closely-related sequences flanking different genes. Once bound to DNA directly or as part of a complex, they can promote or inhibit RNA polymerase recruitment, thereby acting as activators or repressors, respectively. Alternatively, transcription factors can act to recruit coactivators and corepressors or to catalyze histone acetylation and deacetylation. Transcription factors can function downstream of signaling cascades triggered by biological or environmental (ex. hypoxia, hyperthermia) stimuli to alter the expression of target genes. Ligand binding is necessary to activate some transcription factors as this can cause nuclear translocation and changes in the binding affinities for DNA and cofactors. During development, various stimuli can cause transcription factors to up- or down-regulate expression of specific genes at distinct time points to ensure proper development. Transcription factors can function as oncogenes or tumor suppressors and have thus been linked to various cancers. Accordingly, some therapeutic approaches in cancer therapy involve targeting transcription factor families[1].

1. Darnell JE Jr. 2002. Transcription factors as targets for cancer therapy. Nat Rev Cancer. Oct;2(10):740-9.

Transcription Factor Antibodies Top 20 Showcase

View the entire product list by clicking here.

Transcription Factors are involved in transcriptional regulation in the form of up regulation or down regulation acting as either repressors or activators of transcription. We have manufactured more than 3000 antibody products covering almost every known human and mouse transcription factors.

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Showing 451 - 480 of 3946
  Type Catalog # Product Product Images Price (USD)
  pAb ARP32178_P050 ZNF639 antibody - N-terminal region (ARP32178_P050)
Reacts with
Bovine, Human, Horse, Rat, Mouse, Rabbit
Application
WB
$289.00
  pAb ARP32185_P050 NT5C3 antibody - middle region (ARP32185_P050)
Reacts with
Human, Rabbit, Rat, Dog, Zebrafish, Horse, Guinea pig, Mouse, Bovine
Application
WB
$289.00
  pAb ARP32186_T100 KLF3 antibody - N-terminal region (ARP32186_T100)
Reacts with
Human, Bovine, Horse, Rabbit, Guinea pig, Dog, Rat, Mouse
Application
WB
$229.00
  pAb ARP32187_P050 KLF3 Antibody - C-terminal region (ARP32187_P050)
Reacts with
Human, Pig, Rat, Bovine, Dog, Horse, Rabbit, Mouse, Guinea pig
Application
WB
$289.00
  pAb ARP32188_T100 IRX2 antibody - middle region (ARP32188_T100)
Reacts with
Human, Dog, Horse, Mouse, Guinea pig, Rat, Bovine
Application
WB
$229.00
  pAb ARP32189_P050 ZNF746 antibody - middle region (ARP32189_P050)
Reacts with
Rat, Bovine, Pig, Rabbit, Mouse, Human, Guinea pig
Application
IHC, WB
$289.00
  pAb ARP32191_P050 NKX2-3 antibody - middle region (ARP32191_P050)
Reacts with
Human, Dog, Rat, Guinea pig, Bovine, Mouse
Application
WB
$289.00
  pAb ARP32193_P050 ZFPM1 antibody - middle region (ARP32193_P050)
Reacts with
Human, Bovine, Rat
Application
WB
$289.00
  pAb ARP32194_T100 ZFP1 antibody - N-terminal region (ARP32194_T100)
Reacts with
Dog, Bovine, Rabbit, Rat, Pig, Human, Mouse, Horse, Guinea pig
Application
WB
$229.00
  pAb ARP32195_P050 DBP antibody - N-terminal region (ARP32195_P050)
Reacts with
Human, Pig, Horse, Guinea pig, Sheep, Dog, Bovine, Mouse, Rat
Application
IHC, WB
$289.00
  pAb ARP32196_P050 ZNF342 antibody - middle region (ARP32196_P050)
Reacts with
Dog, Rabbit, Rat, Guinea pig, Human, Bovine, Horse, Mouse
Application
WB
$289.00
  pAb ARP32201_P050 ZNF509 antibody - middle region (ARP32201_P050)
Reacts with
Human, Horse, Pig, Bovine, Mouse, Dog
Application
WB
$289.00
  pAb ARP32203_P050 ZNF800 antibody - N-terminal region (ARP32203_P050)
Reacts with
Horse, Human, Bovine, Dog, Pig, Rabbit, Mouse, Rat, Guinea pig
Application
WB
$289.00
  pAb ARP32208_P050 GSH2 antibody - N-terminal region (ARP32208_P050)
Reacts with
Human, Dog, Pig, Horse, Rabbit, Bovine, Rat, Mouse, Guinea pig
Application
IHC, WB
$289.00
  pAb ARP32209_P050 Znf384 Antibody - N-terminal region (ARP32209_P050)
Reacts with
Human, Mouse, Rat, Bovine, Dog, Pig, Horse, Rabbit, Guinea pig
Application
WB
$289.00
  pAb ARP32212_T100 DLX2 antibody - C-terminal region (ARP32212_T100)
Reacts with
Bovine, Dog, Pig, Rat, Guinea pig, Mouse, Human
Application
IHC, WB
$229.00
  pAb ARP32213_P050 DLX3 antibody - N-terminal region (ARP32213_P050)
Reacts with
Pig, Bovine, Human, Sheep, Rat, Dog, Horse, Rabbit, Guinea pig, Mouse
Application
IHC, WB
$289.00
  pAb ARP32221_P050 E2F6 antibody - middle region (ARP32221_P050)
Reacts with
Rat, Dog, Horse, Human, Pig, Mouse, Bovine, Guinea pig
Application
IHC, WB
$289.00
  pAb ARP32221_T100 E2F6 antibody - middle region (ARP32221_T100)
Reacts with
Rat, Dog, Horse, Human, Pig, Mouse, Bovine, Guinea pig
Application
WB
$229.00
  pAb ARP32227_P050 SOX30 antibody - middle region (ARP32227_P050)
Reacts with
Human, Rat, Dog, Pig, Horse, Rabbit, Guinea pig, Bovine, Mouse, Yeast
Application
WB
$289.00
  pAb ARP32231_P050 SP7 antibody - N-terminal region (ARP32231_P050)
Reacts with
Bovine, Pig, Horse, Human, Dog, Rabbit, Mouse, Guinea pig, Rat
Application
IHC, WB
$289.00
  pAb ARP32232_P050 SPIC antibody - C-terminal region (ARP32232_P050)
Reacts with
Pig, Rat, Dog, Horse, Rabbit, Human, Bovine, Mouse, Guinea pig, Zebrafish
Application
WB
$289.00
  pAb ARP32235_P050 OSR1 Antibody - N-terminal region (ARP32235_P050)
Reacts with
Rat, Dog, Horse, Rabbit, Pig, Bovine, Human, Mouse, Guinea pig
Application
WB
$289.00
  pAb ARP32237_P050 ZNF280B antibody - N-terminal region (ARP32237_P050)
Reacts with
Human, Bovine, Pig, Rat, Rabbit, Goat, Dog
Application
WB
$289.00
  pAb ARP32241_P050 EGR1 antibody - N-terminal region (ARP32241_P050)
Reacts with
Human, Pig, Horse, Rat, Bovine, Rabbit, Mouse
Application
IHC, WB
$289.00
  pAb ARP32243_T100 AHR antibody - N-terminal region (ARP32243_T100)
Reacts with
Human, Guinea pig, Dog, Bovine, Sheep, Mouse, Rat, Rabbit
Application
IHC, WB
$229.00
  pAb ARP32244_P050 ZNF48 Antibody - C-terminal region (ARP32244_P050)
Reacts with
Human, Rabbit, Bovine, Pig, Goat, Guinea pig, Dog, Rat, Mouse
Application
WB
$289.00
  pAb ARP32247_T100 ELF3 antibody - middle region (ARP32247_T100)
Reacts with
Horse, Rabbit, Rat, Human, Dog, Mouse, Guinea pig, Bovine
Application
WB
$229.00
  pAb ARP32248_P050 ELF4 antibody - C-terminal region (ARP32248_P050)
Reacts with
Bovine, Pig, Human, Dog, Horse, Rat, Mouse, Rabbit
Application
WB
$289.00
  pAb ARP32253_P050 EPAS1 antibody - middle region (ARP32253_P050)
Reacts with
Bovine, Pig, Dog, Horse, Rabbit, Rat, Guinea pig, Mouse, Human, Zebrafish
Application
WB
$289.00

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Showing 451 - 480 of 3946