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Now Offering Over 85,203 Antibodies & 34,301 Antigens!

Transcription Factor Antibodies

Transcription factors are proteins that regulate gene expression by binding to DNA via one or more DNA-binding domains. This binding is achieved via a combination of electrostatic and van der waals forces and can occur at many closely-related sequences flanking different genes. Once bound to DNA directly or as part of a complex, they can promote or inhibit RNA polymerase recruitment, thereby acting as activators or repressors, respectively. Alternatively, transcription factors can act to recruit coactivators and corepressors or to catalyze histone acetylation and deacetylation. Transcription factors can function downstream of signaling cascades triggered by biological or environmental (ex. hypoxia, hyperthermia) stimuli to alter the expression of target genes. Ligand binding is necessary to activate some transcription factors as this can cause nuclear translocation and changes in the binding affinities for DNA and cofactors. During development, various stimuli can cause transcription factors to up- or down-regulate expression of specific genes at distinct time points to ensure proper development. Transcription factors can function as oncogenes or tumor suppressors and have thus been linked to various cancers. Accordingly, some therapeutic approaches in cancer therapy involve targeting transcription factor families[1].

1. Darnell JE Jr. 2002. Transcription factors as targets for cancer therapy. Nat Rev Cancer. Oct;2(10):740-9.

Transcription Factor Antibodies Top 20 Showcase

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Transcription Factors are involved in transcriptional regulation in the form of up regulation or down regulation acting as either repressors or activators of transcription. We have manufactured more than 3000 antibody products covering almost every known human and mouse transcription factors.

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Showing 451 - 480 of 4137
  Type Catalog # Product Product Images Price (USD)
  pAb ARP34318_T100 CNOT3 antibody - N-terminal region (ARP34318_T100)
Reacts with
Horse, Rabbit, Human, Rat, Bovine, Dog, Pig, Mouse, Guinea pig, Zebrafish
Application
WB
$229.00
  pAb ARP39421_P050 CBX4 Antibody - middle region (ARP39421_P050)
Reacts with
Zebrafish, Human, Bovine, Pig, Horse, Rabbit, Rat, Guinea pig, Dog, Mouse
Application
WB
$289.00
  pAb ARP50143_P050 Frmd5 antibody - N-terminal region (ARP50143_P050)
Reacts with
Mouse, Horse, Human, Rat, Bovine, Dog, Pig, Guinea pig, Rabbit, Zebrafish
Application
WB
$289.00
  pAb ARP50768_P050 ZNF678 Antibody - middle region (ARP50768_P050)
Reacts with
Human, Dog, Bovine, Mouse, Rat, Pig, Horse, Guinea pig, Rabbit
Application
WB
$289.00
  pAb ARP30183_P050 TRAP1 Antibody - N-terminal region (ARP30183_P050)
Reacts with
Human, Rat, Guinea pig, Dog, Mouse
Application
WB
$289.00
  pAb ARP69005_P050 ZMYND15 Antibody - N-terminal region (ARP69005_P050)
Reacts with
Human, Dog, Rabbit, Rat, Pig
Application
WB
$289.00
  pAb ARP61366_P050 CYSLTR1 antibody - C-terminal region (ARP61366_P050)
Reacts with
Human, Bovine, Horse, Dog, Guinea pig, Rabbit
Application
WB
$289.00
  pAb ARP60773_P050 SPANXB1 Antibody - middle region (ARP60773_P050)
Reacts with
Human
Application
WB
$289.00
  pAb ARP31365_P050 ATF1 Antibody - N-terminal region (ARP31365_P050)
Reacts with
Human, Dog, Horse, Rat, Rabbit, Guinea pig, Mouse, Bovine
Application
WB
$289.00
  pAb ARP40086_P050 RFX4 antibody - N-terminal region (ARP40086_P050)
Reacts with
Zebrafish, Human, Mouse, Dog, Horse, Rabbit, Rat, Guinea pig, Yeast
Application
WB
$289.00
  pAb ARP62628_P050 KANK2 antibody - C-terminal region (ARP62628_P050)
Reacts with
Human, Dog, Bovine, Horse, Rat, Pig, Guinea pig, Mouse, Rabbit
Application
WB
$289.00
  pAb ARP30357_T100 TRAF6 Antibody - C-terminal region (ARP30357_T100)
Reacts with
Pig, Horse, Rabbit, Human, Rat, Bovine, Mouse
Application
WB
$229.00
  pAb ARP61755_P050 Tbce antibody - N-terminal region (ARP61755_P050)
Reacts with
Human, Mouse, Pig, Rabbit, Guinea pig, Horse, Bovine, Rat, Dog, Zebrafish, Yeast
Application
WB
$289.00
  pAb ARP64564_P050 DRP2 antibody - middle region (ARP64564_P050)
Reacts with
Human, Horse, Rabbit, Guinea pig, Bovine, Dog, Rat, Mouse
Application
WB
$289.00
  pAb ARP32853_P050 Zhx1 antibody - C-terminal region (ARP32853_P050)
Reacts with
Human, Bovine, Pig, Horse, Rabbit, Rat, Dog, Mouse
Application
WB
$289.00
  pAb ARP47570_P050 ZNF528 Antibody - middle region (ARP47570_P050)
Reacts with
Human, Bovine, Rat, Zebrafish, Horse, Mouse, Pig, Rabbit, Dog
Application
WB
$289.00
  pAb ARP40402_P050 Oas1g antibody - N-terminal region (ARP40402_P050)
Reacts with
Horse, Human, Mouse, Bovine, Dog, Pig, Rat, Rabbit, Guinea pig
Application
WB
$289.00
  pAb ARP68610_P050 MACROD1 Antibody - N-terminal region (ARP68610_P050)
Reacts with
Pig, Horse, Rat, Guinea pig, Bovine, Mouse, Human, Dog
Application
WB
$289.00
  pAb ARP42764_P050 LOC100504025 antibody - C-terminal region (ARP42764_P050)
Reacts with
Zebrafish, Pig, Horse, Rabbit, Human
Application
WB
$289.00
  pAb ARP30347_T100 AFP Antibody - C-terminal region (ARP30347_T100)
Reacts with
Human, Dog, Horse, Bovine, Rat, Mouse, Pig
Application
WB
$229.00
  pAb ARP32518_P050 SEC14L2 Antibody - C-terminal region (ARP32518_P050)
Reacts with
Rat, Human, Pig, Bovine, Dog, Horse, Rabbit, Guinea pig, Mouse, Zebrafish
Application
WB
$289.00
  pAb ARP32237_P050 ZNF280B antibody - N-terminal region (ARP32237_P050)
Reacts with
Human, Bovine, Pig, Rat, Rabbit, Goat, Dog
Application
WB
$289.00
  pAb ARP37462_P050 Ptges2 Antibody - middle region (ARP37462_P050)
Reacts with
Rat, Horse, Mouse, Pig, Guinea pig, Bovine, Dog, Human
Application
WB
$289.00
  pAb ARP64048_P050 PRKAG3 antibody - N-terminal region (ARP64048_P050)
Reacts with
Human
Application
WB
$289.00
  pAb ARP31114_P050 NFE2L1 antibody - C-terminal region (ARP31114_P050)
Reacts with
Mouse, Bovine, Human, Rat, Dog, Rabbit
Application
WB
$289.00
  pAb ARP39531_P050 NR1I2 Antibody - N-terminal region (ARP39531_P050)
Reacts with
Human
Application
WB
$289.00
  pAb ARP32232_P050 SPIC antibody - C-terminal region (ARP32232_P050)
Reacts with
Pig, Rat, Dog, Horse, Rabbit, Human, Bovine, Mouse, Guinea pig, Zebrafish
Application
WB
$289.00
  pAb ARP31305_P050 Lmo1 Antibody - C-terminal region (ARP31305_P050)
Reacts with
Pig, Dog, Human, Horse, Rat, Guinea pig, Mouse, Rabbit, Bovine, Zebrafish
Application
WB
$289.00
  pAb ARP35063_P050 Glra3 antibody - middle region (ARP35063_P050)
Reacts with
Human, Rat, Dog, Pig, Horse, Rabbit, Bovine, Guinea pig, Mouse, Zebrafish
Application
WB
$289.00
  pAb ARP51630_P050 HMGN3 Antibody - middle region (ARP51630_P050)
Reacts with
Mouse, Pig, Dog, Bovine, Horse, Rabbit, Guinea pig, Rat, Human, Zebrafish
Application
WB
$289.00

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Showing 451 - 480 of 4137