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Now Offering Over 85,203 Antibodies & 34,301 Antigens!

Transcription Factor Antibodies

Transcription factors are proteins that regulate gene expression by binding to DNA via one or more DNA-binding domains. This binding is achieved via a combination of electrostatic and van der waals forces and can occur at many closely-related sequences flanking different genes. Once bound to DNA directly or as part of a complex, they can promote or inhibit RNA polymerase recruitment, thereby acting as activators or repressors, respectively. Alternatively, transcription factors can act to recruit coactivators and corepressors or to catalyze histone acetylation and deacetylation. Transcription factors can function downstream of signaling cascades triggered by biological or environmental (ex. hypoxia, hyperthermia) stimuli to alter the expression of target genes. Ligand binding is necessary to activate some transcription factors as this can cause nuclear translocation and changes in the binding affinities for DNA and cofactors. During development, various stimuli can cause transcription factors to up- or down-regulate expression of specific genes at distinct time points to ensure proper development. Transcription factors can function as oncogenes or tumor suppressors and have thus been linked to various cancers. Accordingly, some therapeutic approaches in cancer therapy involve targeting transcription factor families[1].

1. Darnell JE Jr. 2002. Transcription factors as targets for cancer therapy. Nat Rev Cancer. Oct;2(10):740-9.

Transcription Factor Antibodies Top 20 Showcase

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Transcription Factors are involved in transcriptional regulation in the form of up regulation or down regulation acting as either repressors or activators of transcription. We have manufactured more than 3000 antibody products covering almost every known human and mouse transcription factors.

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Showing 451 - 480 of 3998
  Type Catalog # Product Product Images Price (USD)
  pAb ARP39208_P050 Pparg Antibody - C-terminal region (ARP39208_P050)
Reacts with
Mouse, Goat, Human, Horse, Rabbit, Rat, Pig, Bovine, Dog, Sheep, Guinea pig, Zebrafish
Application
WB
$289.00
  pAb ARP35182_P050 ABCC4 antibody - C-terminal region (ARP35182_P050)
Reacts with
Rabbit, Human, Mouse, Dog, Rat, Bovine, Horse, Guinea pig, Yeast
Application
WB
$289.00
  pAb ARP40188_P050 Gapdh Antibody - C-terminal region (ARP40188_P050)
Reacts with
Bovine, Rat, Horse, Rabbit, Guinea pig, Human, Dog, Mouse
Application
WB
$289.00
  pAb ARP43824_P050 Slc31a1 antibody - N-terminal region (ARP43824_P050)
Reacts with
Mouse, Horse, Rat, Human, Dog, Rabbit
Application
WB
$289.00
  pAb ARP33211_P050 Rb1 Antibody - middle region (ARP33211_P050)
Reacts with
Human, Bovine, Dog, Rat, Pig, Horse, Rabbit, Guinea pig, Mouse
Application
WB
$289.00
  pAb ARP30574_P050 ID3 Antibody - N-terminal region (ARP30574_P050)
Reacts with
Pig, Horse, Rabbit, Human, Dog, Sheep, Rat, Bovine, Mouse, Guinea pig
Application
WB
$289.00
  pAb ARP37115_P050 Nkx3-1 Antibody - middle region (ARP37115_P050)
Reacts with
Mouse
Application
WB
$289.00
  pAb ARP63842_P050 NPIP antibody - middle region (ARP63842_P050)
Reacts with
Human
Application
WB
$289.00
  pAb ARP61491_P050 PDLIM7 Antibody - N-terminal region (ARP61491_P050)
Reacts with
Bovine, Human, Horse, Rat, Guinea pig, Mouse, Dog, Zebrafish, Rabbit
Application
WB
$289.00
  pAb ARP51215_P050 Fxn antibody - C-terminal region (ARP51215_P050)
Reacts with
Dog, Human, Rat, Horse, Rabbit, Guinea pig, Mouse, Bovine, Zebrafish, Yeast
Application
WB
$289.00
  pAb ARP72331_P050 ZNF680 Antibody - middle region (ARP72331_P050)
Reacts with
Human
Application
WB
$289.00
  pAb ARP48592_P050 LOC640502 antibody - C-terminal region (ARP48592_P050)
Reacts with
Bovine, Rat, Dog, Pig, Horse, Rabbit, Guinea pig, Human, Mouse, Zebrafish
Application
WB
$289.00
  pAb ARP66349_P050 ESF1 Antibody - C-terminal region (ARP66349_P050)
Reacts with
Human, Pig, Rabbit, Rat, Dog, Horse
Application
WB
$289.00
  pAb ARP53673_P050 CABYR antibody - middle region (ARP53673_P050)
Reacts with
Human, Rat, Mouse, Rabbit, Pig, Dog, Horse, Bovine
Application
WB
$289.00
  pAb ARP31216_P050 Nfe2 Antibody - C-terminal region (ARP31216_P050)
Reacts with
Human, Mouse, Rabbit, Rat, Guinea pig, Dog, Bovine, Horse
Application
WB
$289.00
  pAb ARP62285_P050 MTG1 antibody - N-terminal region (ARP62285_P050)
Reacts with
Human, Horse, Pig, Bovine, Guinea pig, Rat, Mouse, Rabbit
Application
WB
$289.00
  pAb ARP39071_P050 RBPJL Antibody - N-terminal region (ARP39071_P050)
Reacts with
Human
Application
WB
$289.00
  pAb ARP35248_P050 GRIK4 Antibody - C-terminal region (ARP35248_P050)
Reacts with
Human, Dog, Pig, Rabbit, Guinea pig, Rat, Mouse, Horse
Application
WB
$289.00
  pAb ARP56638_P050 Prkab2 antibody - N-terminal region (ARP56638_P050)
Reacts with
Mouse, Bovine, Horse, Rabbit, Rat, Guinea pig, Human, Dog
Application
WB
$289.00
  pAb ARP51695_P050 INTS4 Antibody - C-terminal region (ARP51695_P050)
Reacts with
Human, Rat, Bovine, Dog, Pig, Horse, Rabbit, Guinea pig, Mouse, Zebrafish
Application
WB
$289.00
  pAb ARP37896_P050 Nr2c1 Antibody - middle region (ARP37896_P050)
Reacts with
Rat, Human, Mouse, Dog, Horse, Rabbit
Application
WB
$289.00
  pAb ARP63910_P050 DIAPH1 antibody - C-terminal region (ARP63910_P050)
Reacts with
Human, Dog, Mouse, Rat, Pig, Rabbit, Bovine
Application
WB
$289.00
  pAb ARP72370_P050 TBX20 Antibody - C-terminal region (ARP72370_P050)
Reacts with
Zebrafish, Bovine, Pig, Horse, Rabbit, Rat, Guinea pig, Dog, Mouse, Human
Application
WB
$289.00
  pAb ARP35254_P050 Kctd3 antibody - middle region (ARP35254_P050)
Reacts with
Human, Rat, Dog, Zebrafish, Pig, Horse, Rabbit, Guinea pig, Bovine, Mouse
Application
WB
$289.00
  pAb ARP38148_P050 Meis1 antibody - N-terminal region (ARP38148_P050)
Reacts with
Bovine, Rat, Human, Dog, Horse, Rabbit, Mouse, Guinea pig, Zebrafish
Application
WB
$289.00
  pAb ARP47735_P050 Zfp367 Antibody - C-terminal region (ARP47735_P050)
Reacts with
Horse, Bovine, Rabbit, Pig, Mouse, Rat, Human, Dog, Guinea pig, Zebrafish
Application
WB
$289.00
  pAb ARP48771_P050 Tnik antibody - middle region (ARP48771_P050)
Reacts with
Yeast, Bovine, Dog, Human, Horse, Rabbit, Rat, Guinea pig, Mouse, Zebrafish
Application
WB
$289.00
  pAb ARP38237_P050 SP8 Antibody - middle region (ARP38237_P050)
Reacts with
Zebrafish, Rat, Mouse, Dog, Horse, Rabbit, Guinea pig, Human, Bovine
Application
WB
$289.00
  pAb ARP33388_P050 SUPT6H Antibody - N-terminal region (ARP33388_P050)
Reacts with
Human
Application
WB
$289.00
  pAb ARP51732_P050 EBF4 antibody - C-terminal region (ARP51732_P050)
Reacts with
Human, Bovine, Dog, Pig, Horse, Rabbit, Rat, Mouse, Guinea pig
Application
WB
$289.00

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Showing 451 - 480 of 3998