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Now Offering Over 85,203 Antibodies & 34,301 Antigens!

Transcription Factor Antibodies

Transcription factors are proteins that regulate gene expression by binding to DNA via one or more DNA-binding domains. This binding is achieved via a combination of electrostatic and van der waals forces and can occur at many closely-related sequences flanking different genes. Once bound to DNA directly or as part of a complex, they can promote or inhibit RNA polymerase recruitment, thereby acting as activators or repressors, respectively. Alternatively, transcription factors can act to recruit coactivators and corepressors or to catalyze histone acetylation and deacetylation. Transcription factors can function downstream of signaling cascades triggered by biological or environmental (ex. hypoxia, hyperthermia) stimuli to alter the expression of target genes. Ligand binding is necessary to activate some transcription factors as this can cause nuclear translocation and changes in the binding affinities for DNA and cofactors. During development, various stimuli can cause transcription factors to up- or down-regulate expression of specific genes at distinct time points to ensure proper development. Transcription factors can function as oncogenes or tumor suppressors and have thus been linked to various cancers. Accordingly, some therapeutic approaches in cancer therapy involve targeting transcription factor families[1].

1. Darnell JE Jr. 2002. Transcription factors as targets for cancer therapy. Nat Rev Cancer. Oct;2(10):740-9.

Transcription Factor Antibodies Top 20 Showcase

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Transcription Factors are involved in transcriptional regulation in the form of up regulation or down regulation acting as either repressors or activators of transcription. We have manufactured more than 3000 antibody products covering almost every known human and mouse transcription factors.

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Showing 451 - 480 of 3998
  Type Catalog # Product Product Images Price (USD)
  pAb ARP39495_P050 HOXA11 Antibody - C-terminal region (ARP39495_P050)
Reacts with
Mouse, Zebrafish, Sheep, Bovine, Dog, Horse, Rabbit, Rat, Guinea pig, Human
Application
WB
$289.00
  pAb ARP42381_P050 Tmem2 antibody - N-terminal region (ARP42381_P050)
Reacts with
Human, Rat, Bovine, Dog, Horse, Rabbit, Mouse, Pig
Application
WB
$289.00
  pAb ARP40189_P050 Prmt6 antibody - C-terminal region (ARP40189_P050)
Reacts with
Dog, Horse, Rat, Guinea pig, Bovine, Human, Mouse
Application
WB
$289.00
  pAb ARP38387_P050 Nr5a2 Antibody - C-terminal region (ARP38387_P050)
Reacts with
Human, Bovine, Dog, Sheep, Rabbit, Guinea pig, Horse, Rat, Zebrafish, Mouse
Application
WB
$289.00
  pAb ARP39632_P050 ZNF746 Antibody - N-terminal region (ARP39632_P050)
Reacts with
Human, Rat, Bovine, Dog, Pig, Horse, Rabbit, Guinea pig, Mouse
Application
WB
$289.00
  pAb ARP41905_P050 Sst antibody - N-terminal region (ARP41905_P050)
Reacts with
Goat, Bovine, Horse, Rabbit, Rat, Guinea pig, Sheep, Dog, Mouse, Human
Application
WB
$289.00
  pAb ARP32596_P050 UHRF1 Antibody - C-terminal region (ARP32596_P050)
Reacts with
Human
Application
WB
$289.00
  pAb ARP37127_P050 Rorc antibody - N-terminal region (ARP37127_P050)
Reacts with
Mouse, Rat, Dog, Pig, Human, Guinea pig
Application
WB, IHC
$289.00
  pAb ARP50757_P050 Ovca2 antibody - middle region (ARP50757_P050)
Reacts with
Rat, Horse, Rabbit, Pig, Human, Mouse, Guinea pig, Bovine, Dog
Application
WB
$289.00
  pAb ARP33203_P050 Ovol2 Antibody - middle region (ARP33203_P050)
Reacts with
Mouse, Human, Bovine, Rat, Rabbit, Guinea pig, Dog
Application
WB
$289.00
  pAb ARP52940_P050 Ociad2 antibody - N-terminal region (ARP52940_P050)
Reacts with
Human, Pig, Horse, Dog, Bovine, Rat, Mouse, Rabbit
Application
WB
$289.00
  pAb ARP37108_P050 Nfe2l2 Antibody - N-terminal region (ARP37108_P050)
Reacts with
Rat, Mouse, Rabbit, Bovine, Human, Yeast, Dog
Application
WB
$289.00
  pAb ARP63831_P050 RXFP2 antibody - C-terminal region (ARP63831_P050)
Reacts with
Human, Rabbit, Bovine, Dog, Horse, Rat, Mouse, Guinea pig
Application
WB
$289.00
  pAb ARP56871_P050 Rab23 antibody - middle region (ARP56871_P050)
Reacts with
Rat, Dog, Horse, Rabbit, Mouse, Human, Bovine, Pig, Guinea pig, Zebrafish
Application
WB
$289.00
  pAb ARP50344_P050 ZNF271 Antibody - middle region (ARP50344_P050)
Reacts with
Human, Bovine, Pig, Rat, Rabbit, Horse, Mouse, Dog, Guinea pig
Application
WB
$289.00
  pAb ARP34778_P050 Crem Antibody - C-terminal region (ARP34778_P050)
Reacts with
Sheep, Human, Mouse, Rat, Dog, Pig, Horse, Rabbit, Guinea pig, Bovine, Zebrafish
Application
WB
$289.00
  pAb ARP69905_P050 ZBTB34 Antibody - N-terminal region (ARP69905_P050)
Reacts with
Rabbit, Rat, Guinea pig, Human, Mouse, Bovine, Horse, Dog
Application
WB
$289.00
  pAb ARP53554_P050 HSD17B3 antibody - N-terminal region (ARP53554_P050)
Reacts with
Human, Rat, Horse
Application
WB
$289.00
  pAb ARP31212_P050 MITF Antibody - middle region (ARP31212_P050)
Reacts with
Human, Pig, Bovine, Horse, Rabbit, Rat, Guinea pig, Dog, Sheep, Mouse
Application
WB
$289.00
  pAb ARP72898_P050 SMARCD3 Antibody - C-terminal region (ARP72898_P050)
Reacts with
Zebrafish, Human, Dog, Pig, Horse, Rabbit, Rat, Guinea pig, Bovine, Mouse
Application
WB
$289.00
  pAb ARP62226_P050 PPP1R16B antibody - N-terminal region (ARP62226_P050)
Reacts with
Mouse, Rat, Dog, Pig, Rabbit, Guinea pig, Bovine, Human
Application
WB
$289.00
  pAb ARP34904_P050 ZMYND8 Antibody - C-terminal region (ARP34904_P050)
Reacts with
Human, Dog, Horse, Rat, Bovine, Mouse
Application
WB
$289.00
  pAb ARP56585_P050 Pfkfb4 antibody - middle region (ARP56585_P050)
Reacts with
Human, Mouse, Dog, Pig, Horse, Rabbit, Rat, Guinea pig, Bovine, Yeast, Zebrafish
Application
WB
$289.00
  pAb ARP37877_P050 Runx1 Antibody - N-terminal region (ARP37877_P050)
Reacts with
Mouse, Rat, Pig, Human, Bovine, Dog, Rabbit, Guinea pig
Application
WB
$289.00
  pAb ARP63784_P050 TUBB3 antibody - C-terminal region (ARP63784_P050)
Reacts with
Human, Zebrafish, Pig, Horse, Rabbit, Rat, Guinea pig, Mouse, Dog, Bovine
Application
WB
$289.00
  pAb ARP39664_P050 MXD3 Antibody - C-terminal region (ARP39664_P050)
Reacts with
Bovine, Dog, Pig, Horse, Rabbit, Rat, Human, Mouse, Guinea pig, Zebrafish
Application
WB
$289.00
  pAb ARP35189_P050 Cacng2 antibody - middle region (ARP35189_P050)
Reacts with
Bovine, Zebrafish, Pig, Horse, Rabbit, Rat, Guinea pig, Dog, Mouse, Human
Application
WB
$289.00
  pAb ARP58031_P050 MID1 Antibody - N-terminal region (ARP58031_P050)
Reacts with
Human, Mouse, Bovine, Dog, Pig, Horse, Rat, Guinea pig, Rabbit, Zebrafish
Application
WB
$289.00
  pAb ARP34875_P050 FOXK2 antibody - C-terminal region (ARP34875_P050)
Reacts with
Human
Application
WB
$289.00
  pAb ARP34738_T100 TRIM14 antibody - N-terminal region (ARP34738_T100)
Reacts with
Human, Rat, Bovine, Pig, Horse, Mouse, Dog, Rabbit, Guinea pig
Application
WB
$229.00

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Showing 451 - 480 of 3998