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Transcription Factor Antibodies

Transcription factors are proteins that regulate gene expression by binding to DNA via one or more DNA-binding domains. This binding is achieved via a combination of electrostatic and van der waals forces and can occur at many closely-related sequences flanking different genes. Once bound to DNA directly or as part of a complex, they can promote or inhibit RNA polymerase recruitment, thereby acting as activators or repressors, respectively. Alternatively, transcription factors can act to recruit coactivators and corepressors or to catalyze histone acetylation and deacetylation. Transcription factors can function downstream of signaling cascades triggered by biological or environmental (ex. hypoxia, hyperthermia) stimuli to alter the expression of target genes. Ligand binding is necessary to activate some transcription factors as this can cause nuclear translocation and changes in the binding affinities for DNA and cofactors. During development, various stimuli can cause transcription factors to up- or down-regulate expression of specific genes at distinct time points to ensure proper development. Transcription factors can function as oncogenes or tumor suppressors and have thus been linked to various cancers. Accordingly, some therapeutic approaches in cancer therapy involve targeting transcription factor families[1].

1. Darnell JE Jr. 2002. Transcription factors as targets for cancer therapy. Nat Rev Cancer. Oct;2(10):740-9.

Transcription Factor Antibodies Top 20 Showcase

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Transcription Factors are involved in transcriptional regulation in the form of up regulation or down regulation acting as either repressors or activators of transcription. We have manufactured more than 3000 antibody products covering almost every known human and mouse transcription factors.

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Showing 451 - 480 of 4219
  • TRIAL 
    SCML4 Antibody - C-terminal region (ARP38975_P050) in Human NCI-H226 using Western Blot

    SCML4 Antibody - C-terminal region (ARP38975_P050)

    Protein Name:Sex comb on midleg-like protein 4
    Catalog #:ARP38975_P050
    Type: pAb
    Reacts with: Cow, Dog, Guinea Pig, Horse, Human, Mouse, Pig, Rabbit, Rat, Zebrafish
    Application: WB
    Product Size: 100 ul
    Price (USD): $289.00
  • TRIAL 
    EIF3I antibody - middle region (ARP64825_P050) in Human HeLa using Western Blot
    EIF3I antibody - middle region (ARP64825_P050) in Human HeLa using Western Blot

    EIF3I antibody - middle region (ARP64825_P050)

    Protein Name:Eukaryotic translation initiation factor 3 subunit I
    Catalog #:ARP64825_P050
    Type: pAb
    Reacts with: Cow, Dog, Guinea Pig, Horse, Human, Mouse, Rabbit, Rat
    Application: WB
    Product Size: 100 ul
    Price (USD): $289.00
  • TRIAL 
    Kcnh2 antibody - C-terminal region (ARP34928_P050) in Mouse Kidney using Western Blot

    Kcnh2 antibody - C-terminal region (ARP34928_P050)

    Protein Name:Potassium voltage-gated channel subfamily H member 2
    Catalog #:ARP34928_P050
    Type: pAb
    Reacts with: Cow, Dog, Guinea Pig, Horse, Human, Mouse, Pig, Rabbit, Rat
    Application: WB
    Product Size: 100 ul
    Price (USD): $289.00
  • TRIAL 
    PARP8 antibody - C-terminal region (ARP33771_P050) in Human HeLa using Western Blot

    PARP8 antibody - C-terminal region (ARP33771_P050)

    Protein Name:Poly [ADP-ribose] polymerase 8
    Catalog #:ARP33771_P050
    Type: pAb
    Reacts with: Cow, Dog, Guinea Pig, Horse, Human, Mouse, Rabbit, Rat, Zebrafish
    Application: WB
    Product Size: 100 ul
    Price (USD): $289.00
  • TRIAL 
    STK17A Antibody - C-terminal region (ARP58888_P050) in Human Fetal Heart using Western Blot

    STK17A Antibody - C-terminal region (ARP58888_P050)

    Protein Name:Serine/threonine-protein kinase 17A
    Catalog #:ARP58888_P050
    Type: pAb
    Reacts with: Cow, Dog, Guinea Pig, Horse, Human, Pig, Rabbit, Rat
    Application: WB
    Product Size: 100 ul
    Price (USD): $289.00
  • TRIAL 
    NPY2R Antibody - N-terminal region (ARP30727_P050) in Human Esophagus Tumor using Western Blot

    NPY2R Antibody - N-terminal region (ARP30727_P050)

    Protein Name:Neuropeptide Y receptor type 2
    Catalog #:ARP30727_P050
    Type: pAb
    Reacts with: Cow, Guinea Pig, Horse, Human, Mouse, Pig, Rabbit, Rat
    Application: WB
    Product Size: 100 ul
    Price (USD): $289.00
  • TRIAL 
    Schip1 antibody - N-terminal region (ARP53777_P050) in Mouse Heart using Western Blot

    Schip1 antibody - N-terminal region (ARP53777_P050)

    Protein Name:Schwannomin-interacting protein 1
    Catalog #:ARP53777_P050
    Type: pAb
    Reacts with: Cow, Dog, Goat, Guinea Pig, Horse, Human, Mouse, Rabbit, Rat, Yeast, Zebrafish
    Application: WB
    Product Size: 100 ul
    Price (USD): $289.00
  • TRIAL 
    ZNF735 Antibody - middle region (ARP72087_P050) in Human 721_B using Western Blot

    ZNF735 Antibody - middle region (ARP72087_P050)

    Protein Name:
    Catalog #:ARP72087_P050
    Type: pAb
    Reacts with: Human
    Application: WB
    Product Size: 100 ul
    Price (USD): $289.00
  • TRIAL 
    Hmg20b antibody - middle region (ARP38783_P050) in Rat Muscle using Western Blot

    Hmg20b antibody - middle region (ARP38783_P050)

    Protein Name:High mobility group 20 B (Predicted), isoform CRA_a EMBL EDL89157.1
    Catalog #:ARP38783_P050
    Type: pAb
    Reacts with: Cow, Dog, Guinea Pig, Horse, Human, Mouse, Rabbit, Rat, Yeast, Zebrafish
    Application: WB
    Product Size: 100 ul
    Price (USD): $289.00
  • TRIAL 
    Wiz Antibody - C-terminal region (ARP36007_P050) in Mouse Spleen using Western Blot

    Wiz Antibody - C-terminal region (ARP36007_P050)

    Protein Name:Protein Wiz
    Catalog #:ARP36007_P050
    Type: pAb
    Reacts with: Cow, Dog, Horse, Human, Mouse, Pig, Rabbit, Rat
    Application: WB
    Product Size: 100 ul
    Price (USD): $289.00
  • TRIAL 
    Rangap1 antibody - N-terminal region (ARP56510_P050) in Mouse Heart using Western Blot

    Rangap1 antibody - N-terminal region (ARP56510_P050)

    Protein Name:Rangap1 protein EMBL AAH14855.1
    Catalog #:ARP56510_P050
    Type: pAb
    Reacts with: Cow, Dog, Guinea Pig, Horse, Human, Mouse, Rabbit, Rat, Zebrafish
    Application: WB
    Product Size: 100 ul
    Price (USD): $289.00
  • TRIAL 
    Foxk1 Antibody - middle region (ARP37943_P050) in Mouse Liver using Western Blot

    Foxk1 Antibody - middle region (ARP37943_P050)

    Protein Name:Forkhead box protein K1
    Catalog #:ARP37943_P050
    Type: pAb
    Reacts with: Cow, Dog, Guinea Pig, Horse, Human, Mouse, Rabbit, Rat, Zebrafish
    Application: WB
    Product Size: 100 ul
    Price (USD): $289.00
  • TRIAL 
    MRGPRX4 antibody - C-terminal region (ARP59927_P050) in Human COLO205 using Western Blot

    MRGPRX4 antibody - C-terminal region (ARP59927_P050)

    Protein Name:Mas-related G-protein coupled receptor member X4
    Catalog #:ARP59927_P050
    Type: pAb
    Reacts with: Human, Mouse, Rabbit
    Application: WB
    Product Size: 100 ul
    Price (USD): $289.00
  • TRIAL 
    Lrp2bp antibody - middle region (ARP42516_P050) in Rat Lung using Western Blot

    Lrp2bp antibody - middle region (ARP42516_P050)

    Protein Name:LRP2-binding protein
    Catalog #:ARP42516_P050
    Type: pAb
    Reacts with: Cow, Dog, Guinea Pig, Horse, Human, Mouse, Pig, Rabbit, Rat, Zebrafish
    Application: WB
    Product Size: 100 ul
    Price (USD): $289.00
  • TRIAL 
    Rfc1 Antibody - C-terminal region (ARP56521_P050) in Rat Testis using Western Blot

    Rfc1 Antibody - C-terminal region (ARP56521_P050)

    Protein Name:Replication factor C subunit 1
    Catalog #:ARP56521_P050
    Type: pAb
    Reacts with: Dog, Guinea Pig, Horse, Human, Mouse, Rabbit, Rat
    Application: WB
    Product Size: 100 ul
    Price (USD): $289.00
  • TRIAL 
    Pparg Antibody - C-terminal region (ARP39208_P050) in Rat Kidney using Western Blot

    Pparg Antibody - C-terminal region (ARP39208_P050)

    Protein Name:Peroxisome proliferator-activated receptor gamma
    Catalog #:ARP39208_P050
    Type: pAb
    Reacts with: Cow, Dog, Goat, Guinea Pig, Horse, Human, Mouse, Rabbit, Rat, Sheep, Zebrafish
    Application: WB
    Product Size: 100 ul
    Price (USD): $289.00
  • TRIAL 
    Rab13 antibody - middle region (ARP42892_P050) in Mouse Heart using Western Blot

    Rab13 antibody - middle region (ARP42892_P050)

    Protein Name:Ras-related protein Rab-13
    Catalog #:ARP42892_P050
    Type: pAb
    Reacts with: Cow, Dog, Guinea Pig, Horse, Human, Mouse, Rabbit, Rat, Zebrafish
    Application: WB
    Product Size: 100 ul
    Price (USD): $289.00
  • TRIAL 
    ZNF426 antibody - N-terminal region (ARP33566_T100) in Human Fetal liver using Western Blot

    ZNF426 antibody - N-terminal region (ARP33566_T100)

    Protein Name:Zinc finger protein 426
    Catalog #:ARP33566_T100
    Type: pAb
    Reacts with: Human, Mouse, Rat
    Application: WB
    Product Size: 100 ul
    Price (USD): $229.00
  • TRIAL 
    BANP Antibody - N-terminal region (ARP34748_P050) in Human PANC1 using Western Blot

    BANP Antibody - N-terminal region (ARP34748_P050)

    Protein Name:protein BANP
    Catalog #:ARP34748_P050
    Type: pAb
    Reacts with: Cow, Dog, Guinea Pig, Horse, Human, Mouse, Rabbit, Rat, Yeast
    Application: WB
    Product Size: 100 ul
    Price (USD): $289.00
  • TRIAL 
    Irf5 Antibody - middle region (ARP37179_P050) in Mouse Heart using Western Blot

    IRF5 Antibody - middle region (ARP37179_P050)

    Protein Name:interferon regulatory factor 5
    Catalog #:ARP37179_P050
    Type: pAb
    Reacts with: Cow, Dog, Guinea Pig, Horse, Human, Mouse, Pig, Rabbit, Rat
    Application: WB
    Product Size: 100 ul
    Price (USD): $289.00
  • TRIAL 
    CDC73 antibody - C-terminal region (ARP63639_P050) in Human MDA-MB-435S using Western Blot

    CDC73 antibody - C-terminal region (ARP63639_P050)

    Protein Name:Parafibromin
    Catalog #:ARP63639_P050
    Type: pAb
    Reacts with: Cow, Dog, Horse, Human, Mouse, Rabbit, Rat, Zebrafish
    Application: WB
    Product Size: 100 ul
    Price (USD): $289.00
  • TRIAL 
    METTL3 antibody - C-terminal region (ARP34591_P050) in Human HepG2 using Western Blot

    METTL3 antibody - C-terminal region (ARP34591_P050)

    Protein Name:N6-adenosine-methyltransferase 70 kDa subunit
    Catalog #:ARP34591_P050
    Type: pAb
    Reacts with: Cow, Dog, Goat, Guinea Pig, Horse, Human, Mouse, Rabbit, Rat, Zebrafish
    Application: WB
    Product Size: 100 ul
    Price (USD): $289.00
  • TRIAL 
    MGC4618 antibody - N-terminal region (ARP34360_T100) in Human HepG2 using Western Blot

    MGC4618 antibody - N-terminal region (ARP34360_T100)

    Protein Name:Transmembrane protein 175
    Catalog #:ARP34360_T100
    Type: pAb
    Reacts with: Dog, Guinea Pig, Horse, Human, Mouse, Rat
    Application: WB
    Product Size: 100 ul
    Price (USD): $229.00
  • TRIAL 
    LTV1 antibody - C-terminal region (ARP64882_P050) in Human Placenta using Western Blot

    LTV1 antibody - C-terminal region (ARP64882_P050)

    Protein Name:Protein LTV1 homolog
    Catalog #:ARP64882_P050
    Type: pAb
    Reacts with: Cow, Dog, Guinea Pig, Horse, Human, Mouse, Rabbit, Rat
    Application: WB
    Product Size: 100 ul
    Price (USD): $289.00

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Showing 451 - 480 of 4219