website statistics

Aviva Systems Biology

Account Login 

Aviva's office will be closed on 4/18/2014 for Good Friday holiday. Please go here for more info.

Now Offering Over 85,203 Antibodies & 34,301 Antigens!

Transcription Factor Antibodies

Transcription factors are proteins that regulate gene expression by binding to DNA via one or more DNA-binding domains. This binding is achieved via a combination of electrostatic and van der waals forces and can occur at many closely-related sequences flanking different genes. Once bound to DNA directly or as part of a complex, they can promote or inhibit RNA polymerase recruitment, thereby acting as activators or repressors, respectively. Alternatively, transcription factors can act to recruit coactivators and corepressors or to catalyze histone acetylation and deacetylation. Transcription factors can function downstream of signaling cascades triggered by biological or environmental (ex. hypoxia, hyperthermia) stimuli to alter the expression of target genes. Ligand binding is necessary to activate some transcription factors as this can cause nuclear translocation and changes in the binding affinities for DNA and cofactors. During development, various stimuli can cause transcription factors to up- or down-regulate expression of specific genes at distinct time points to ensure proper development. Transcription factors can function as oncogenes or tumor suppressors and have thus been linked to various cancers. Accordingly, some therapeutic approaches in cancer therapy involve targeting transcription factor families[1].

1. Darnell JE Jr. 2002. Transcription factors as targets for cancer therapy. Nat Rev Cancer. Oct;2(10):740-9.

Transcription Factor Antibodies Top 20 Showcase

View the entire product list by clicking here.

Transcription Factors are involved in transcriptional regulation in the form of up regulation or down regulation acting as either repressors or activators of transcription. We have manufactured more than 3000 antibody products covering almost every known human and mouse transcription factors.

Page of 132

Showing 421 - 450 of 3946
  Type Catalog # Product Product Images Price (USD)
  pAb ARP32053_P050 NPAS1 antibody - C-terminal region (ARP32053_P050)
Reacts with
Rabbit, Human, Mouse, Rat, Pig, Dog
Application
IHC, WB
$289.00
  pAb ARP32062_P050 PAWR antibody - middle region (ARP32062_P050)
Reacts with
Rat, Guinea pig, Human, Horse, Mouse, Rabbit
Application
IHC, WB
$289.00
  pAb ARP32064_P050 PAX4 antibody - middle region (ARP32064_P050)
Reacts with
Human, Mouse, Rabbit, Dog, Bovine, Pig, Horse, Guinea pig, Rat
Application
WB
$289.00
  pAb ARP32065_P050 MYEF2 antibody - N-terminal region (ARP32065_P050)
Reacts with
Human, Mouse, Rat, Rabbit, Guinea pig, Bovine, Horse, Dog
Application
WB
$289.00
  pAb ARP32066_T100 IRX4 antibody - N-terminal region (ARP32066_T100)
Reacts with
Bovine, Human, Pig, Rat, Mouse
Application
WB
$229.00
  pAb ARP32068_P050 PAX7 antibody - middle region (ARP32068_P050)
Reacts with
Rat, Bovine, Dog, Horse, Rabbit, Mouse, Guinea pig, Human, Zebrafish
Application
WB
$289.00
  pAb ARP32069_P050 PBX2 antibody - N-terminal region (ARP32069_P050)
Reacts with
Pig, Horse, Guinea pig, Mouse, Human, Rat
Application
WB
$289.00
  pAb ARP32070_T100 PBX3 antibody - N-terminal region (ARP32070_T100)
Reacts with
Human, Rat, Mouse, Guinea pig, Bovine, Zebrafish
Application
IHC, WB
$229.00
  pAb ARP32076_T100 ZNF691 antibody - N-terminal region (ARP32076_T100)
Reacts with
Human, Bovine, Rat, Pig, Mouse, Dog, Horse, Rabbit
Application
WB
$229.00
  pAb ARP32081_P050 PHOX2A antibody - N-terminal region (ARP32081_P050)
Reacts with
Dog, Bovine, Pig, Horse, Rabbit, Rat, Guinea pig, Human, Mouse
Application
WB
$289.00
  pAb ARP32084_P050 NR2E1 antibody - N-terminal region (ARP32084_P050)
Reacts with
Horse, Human, Rabbit, Mouse, Bovine, Dog, Pig, Rat, Guinea pig, Zebrafish
Application
IHC, WB
$289.00
  pAb ARP32088_P050 Ywhae antibody - C-terminal region (ARP32088_P050)
Reacts with
Human, Horse, Rabbit, Rat, Guinea pig, Mouse, Bovine, Sheep, Zebrafish
Application
IHC, WB
$289.00
  pAb ARP32102_P050 DVL2 antibody - N-terminal region (ARP32102_P050)
Reacts with
Human, Rat, Bovine, Dog, Horse, Rabbit, Guinea pig, Mouse, Zebrafish, Yeast
Application
IHC, WB
$289.00
  pAb ARP32107_P050 FOXO1 antibody - C-terminal region (ARP32107_P050)
Reacts with
Pig, Bovine, Dog, Horse, Rabbit, Rat, Guinea pig, Human, Mouse, Zebrafish
Application
WB
$289.00
  pAb ARP32110_P050 FOXO4 antibody - C-terminal region (ARP32110_P050)
Reacts with
Human, Mouse, Rat, Dog, Pig, Horse, Guinea pig, Bovine
Application
WB
$289.00
  pAb ARP32134_P050 MYF5 antibody - N-terminal region (ARP32134_P050)
Reacts with
Mouse, Goat, Pig, Rat, Horse, Rabbit, Guinea pig, Human, Bovine, Sheep, Zebrafish, Dog
Application
WB
$289.00
  pAb ARP32135_P050 MYF6 antibody - N-terminal region (ARP32135_P050)
Reacts with
Zebrafish, Sheep, Goat, Dog, Horse, Rabbit, Rat, Guinea pig, Mouse, Human, Bovine
Application
IHC, WB
$289.00
  pAb ARP32136_P050 TAF11 antibody - N-terminal region (ARP32136_P050)
Reacts with
Pig, Rat, Guinea pig, Human, Horse, Rabbit, Bovine, Mouse
Application
WB
$289.00
  pAb ARP32142_P050 ZNF706 antibody - N-terminal region (ARP32142_P050)
Reacts with
Mouse, Rat, Dog, Human, Pig, Horse, Rabbit, Guinea pig, Bovine, Zebrafish
Application
WB
$289.00
  pAb ARP32145_P050 Rnf166 antibody - middle region (ARP32145_P050)
Reacts with
Mouse, Human, Horse, Rat, Guinea pig, Dog, Bovine, Zebrafish
Application
WB
$289.00
  pAb ARP32148_P050 ZNF526 antibody - N-terminal region (ARP32148_P050)
Reacts with
Bovine, Human, Dog, Horse, Rabbit, Rat, Guinea pig, Mouse
Application
WB
$289.00
  pAb ARP32149_P050 ERCC8 antibody - N-terminal region (ARP32149_P050)
Reacts with
Human, Zebrafish, Mouse, Dog, Pig, Rabbit, Rat, Guinea pig, Bovine
Application
WB
$289.00
  pAb ARP32150_P050 RNF12 antibody - N-terminal region (ARP32150_P050)
Reacts with
Dog, Pig, Horse, Rat, Guinea pig, Human, Bovine, Rabbit, Mouse
Application
WB
$289.00
  pAb ARP32151_P050 RNF12 antibody - C-terminal region (ARP32151_P050)
Reacts with
Human, Bovine, Dog, Pig, Horse, Rabbit, Zebrafish, Rat, Guinea pig, Mouse, Yeast
Application
IHC, WB
$289.00
  pAb ARP32154_P050 ZNF787 antibody - middle region (ARP32154_P050)
Reacts with
Rat, Bovine, Dog, Pig, Guinea pig, Human, Mouse
Application
WB
$289.00
  pAb ARP32159_P050 TFDP3 antibody - middle region (ARP32159_P050)
Reacts with
Human
Application
WB
$289.00
  pAb ARP32164_P050 RAX antibody - N-terminal region (ARP32164_P050)
Reacts with
Human, Dog, Rat, Guinea pig
Application
WB
$289.00
  pAb ARP32167_T100 CREBL1 antibody - N-terminal region (ARP32167_T100)
Reacts with
Rat, Human, Horse, Mouse, Bovine, Pig, Guinea pig
Application
WB
$229.00
  pAb ARP32172_P050 Zfp580 antibody - middle region (ARP32172_P050)
Reacts with
Rat, Dog, Human, Mouse, Guinea pig
Application
WB
$289.00
  pAb ARP32174_P050 GSC antibody - N-terminal region (ARP32174_P050)
Reacts with
Pig, Human, Dog, Bovine, Rat, Mouse
Application
IHC, WB
$289.00

Page of 132

Showing 421 - 450 of 3946