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Transcription Factor Antibodies

Transcription factors are proteins that regulate gene expression by binding to DNA via one or more DNA-binding domains. This binding is achieved via a combination of electrostatic and van der waals forces and can occur at many closely-related sequences flanking different genes. Once bound to DNA directly or as part of a complex, they can promote or inhibit RNA polymerase recruitment, thereby acting as activators or repressors, respectively. Alternatively, transcription factors can act to recruit coactivators and corepressors or to catalyze histone acetylation and deacetylation. Transcription factors can function downstream of signaling cascades triggered by biological or environmental (ex. hypoxia, hyperthermia) stimuli to alter the expression of target genes. Ligand binding is necessary to activate some transcription factors as this can cause nuclear translocation and changes in the binding affinities for DNA and cofactors. During development, various stimuli can cause transcription factors to up- or down-regulate expression of specific genes at distinct time points to ensure proper development. Transcription factors can function as oncogenes or tumor suppressors and have thus been linked to various cancers. Accordingly, some therapeutic approaches in cancer therapy involve targeting transcription factor families[1].

1. Darnell JE Jr. 2002. Transcription factors as targets for cancer therapy. Nat Rev Cancer. Oct;2(10):740-9.

Transcription Factor Antibodies Top 20 Showcase

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Transcription Factors are involved in transcriptional regulation in the form of up regulation or down regulation acting as either repressors or activators of transcription. We have manufactured more than 3000 antibody products covering almost every known human and mouse transcription factors.

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Showing 421 - 450 of 4219
  • TRIAL 
    Ovol1 Antibody - C-terminal region (ARP37272_P050) in Rat Pancreas using Western Blot

    Ovol1 Antibody - C-terminal region (ARP37272_P050)

    Protein Name:Ovo-like 1(Drosophila) (Predicted) EMBL EDM12506.1
    Catalog #:ARP37272_P050
    Type: pAb
    Reacts with: Cow, Dog, Goat, Guinea Pig, Horse, Human, Mouse, Rabbit, Rat
    Application: WB
    Product Size: 100 ul
    Price (USD): $289.00
  • TRIAL 
    ZMYM6 Antibody - N-terminal region (ARP34882_P050) in Human Lung Tumor using Western Blot

    ZMYM6 Antibody - N-terminal region (ARP34882_P050)

    Protein Name:Zinc finger MYM-type protein 6
    Catalog #:ARP34882_P050
    Type: pAb
    Reacts with: Human
    Application: WB
    Product Size: 100 ul
    Price (USD): $289.00
  • TRIAL 
    SCG5 antibody - N-terminal region (ARP63847_P050) in Human Jurkat using Western Blot

    SCG5 antibody - N-terminal region (ARP63847_P050)

    Protein Name:Neuroendocrine protein 7B2
    Catalog #:ARP63847_P050
    Type: pAb
    Reacts with: Cow, Dog, Guinea Pig, Horse, Human, Mouse, Rabbit, Rat, Zebrafish
    Application: WB
    Product Size: 100 ul
    Price (USD): $289.00
  • TRIAL 
    Taf7l Antibody - C-terminal region (ARP37401_P050) in Mouse Muscle using Western Blot

    Taf7l Antibody - C-terminal region (ARP37401_P050)

    Protein Name:Transcription initiation factor TFIID subunit 7-like
    Catalog #:ARP37401_P050
    Type: pAb
    Reacts with: Cow, Mouse, Pig, Rat
    Application: WB
    Product Size: 100 ul
    Price (USD): $289.00
  • TRIAL 
    ESR2 antibody - N-terminal region (ARP31652_T100) in Human HepG2 using Western Blot

    ESR2 antibody - N-terminal region (ARP31652_T100)

    Protein Name:Estrogen receptor beta
    Catalog #:ARP31652_T100
    Type: pAb
    Reacts with: Cow, Dog, Goat, Guinea Pig, Horse, Human, Mouse, Pig, Rabbit, Rat, Sheep
    Application: WB
    Product Size: 100 ul
    Price (USD): $229.00
  • TRIAL 
    Hoxd9 Antibody - N-terminal region (ARP39063_P050) in Rat Thymus using Western Blot

    Hoxd9 Antibody - N-terminal region (ARP39063_P050)

    Protein Name:Homeobox protein Hox-D9
    Catalog #:ARP39063_P050
    Type: pAb
    Reacts with: Cow, Guinea Pig, Horse, Human, Mouse, Rabbit, Rat
    Application: WB
    Product Size: 100 ul
    Price (USD): $289.00
  • TRIAL 
    ACSS2 antibody - C-terminal region (ARP61138_P050) in Human Fetal heart using Western Blot

    ACSS2 antibody - C-terminal region (ARP61138_P050)

    Protein Name:Acetyl-coenzyme A synthetase, cytoplasmic
    Catalog #:ARP61138_P050
    Type: pAb
    Reacts with: Cow, Dog, Goat, Guinea Pig, Horse, Human, Mouse, Rabbit, Rat, Zebrafish
    Application: WB
    Product Size: 100 ul
    Price (USD): $289.00
  • TRIAL 
    Ccdc59 Antibody - C-terminal region (ARP67435_P050) in Mouse Thymus using Western Blot

    Ccdc59 Antibody - C-terminal region (ARP67435_P050)

    Protein Name:Thyroid transcription factor 1-associated protein 26
    Catalog #:ARP67435_P050
    Type: pAb
    Reacts with: Cow, Dog, Guinea Pig, Horse, Human, Mouse, Pig, Rabbit, Rat, Yeast
    Application: WB
    Product Size: 100 ul
    Price (USD): $289.00
  • TRIAL 
    CDK7 Antibody - N-terminal region (ARP31341_P050) in Human Fetal Kidney using Western Blot

    CDK7 Antibody - N-terminal region (ARP31341_P050)

    Protein Name:Cyclin-dependent kinase 7
    Catalog #:ARP31341_P050
    Type: pAb
    Reacts with: Cow, Dog, Guinea Pig, Horse, Human, Mouse, Rabbit, Rat, Zebrafish
    Application: WB
    Product Size: 100 ul
    Price (USD): $289.00
  • TRIAL 
    Gps1 Antibody - N-terminal region (ARP32354_P050) in Rat Brain using Western Blot

    Gps1 Antibody - N-terminal region (ARP32354_P050)

    Protein Name:COP9 signalosome complex subunit 1
    Catalog #:ARP32354_P050
    Type: pAb
    Reacts with: Cow, Dog, Guinea Pig, Horse, Human, Mouse, Rat, Zebrafish
    Application: WB
    Product Size: 100 ul
    Price (USD): $289.00
  • TRIAL 
    E2f5 antibody - C-terminal region (ARP57966_P050) in Mouse Pancreas using Western Blot

    E2f5 antibody - C-terminal region (ARP57966_P050)

    Protein Name:Transcription factor E2F5
    Catalog #:ARP57966_P050
    Type: pAb
    Reacts with: Cow, Dog, Guinea Pig, Horse, Human, Mouse, Pig, Rat
    Application: WB
    Product Size: 100 ul
    Price (USD): $289.00
  • TRIAL 
    VSIG4 antibody - N-terminal region (ARP41590_P050) in COLO205 using Western Blot

    VSIG4 antibody - N-terminal region (ARP41590_P050)

    Protein Name:
    Catalog #:ARP41590_P050
    Type: pAb
    Reacts with: Cow, Dog, Guinea Pig, Horse, Human, Mouse, Pig, Rabbit, Rat
    Application: WB
    Product Size: 100 ul
    Price (USD): $289.00
  • TRIAL 
    Ptges2 Antibody - middle region (ARP37462_P050) in Mouse Spleen using Western Blot

    Ptges2 Antibody - middle region (ARP37462_P050)

    Protein Name:Prostaglandin E synthase 2
    Catalog #:ARP37462_P050
    Type: pAb
    Reacts with: Cow, Dog, Guinea Pig, Horse, Human, Mouse, Rat
    Application: WB
    Product Size: 100 ul
    Price (USD): $289.00
  • TRIAL 
    Pcdh10 antibody - C-terminal region (ARP41634_P050) in Mouse Pancreas using Western Blot

    Pcdh10 antibody - C-terminal region (ARP41634_P050)

    Protein Name:Protein Pcdh10 Ensembl ENSMUSP00000131073
    Catalog #:ARP41634_P050
    Type: pAb
    Reacts with: Cow, Dog, Guinea Pig, Human, Mouse, Rabbit, Rat, Zebrafish
    Application: WB
    Product Size: 100 ul
    Price (USD): $289.00
  • TRIAL 
    HOXA11 Antibody - C-terminal region (ARP39495_P050) in Human Ovary Tumor using Western Blot

    HOXA11 Antibody - C-terminal region (ARP39495_P050)

    Protein Name:Homeobox protein Hox-D11
    Catalog #:ARP39495_P050
    Type: pAb
    Reacts with: Cow, Dog, Guinea Pig, Horse, Human, Mouse, Rabbit, Rat, Sheep, Zebrafish
    Application: WB
    Product Size: 100 ul
    Price (USD): $289.00
  • TRIAL 
    Cbll1 antibody - C-terminal region (ARP33600_P050) in Mouse Kidney using Western Blot

    Cbll1 antibody - C-terminal region (ARP33600_P050)

    Protein Name:E3 ubiquitin-protein ligase Hakai
    Catalog #:ARP33600_P050
    Type: pAb
    Reacts with: Cow, Dog, Horse, Human, Mouse, Pig, Rat
    Application: WB
    Product Size: 100 ul
    Price (USD): $289.00
  • TRIAL 
    ZBTB41 Antibody - C-terminal region (ARP50860_P050) in Human THP-1 using Western Blot

    ZBTB41 Antibody - C-terminal region (ARP50860_P050)

    Protein Name:Zinc finger and BTB domain-containing protein 41
    Catalog #:ARP50860_P050
    Type: pAb
    Reacts with: Cow, Dog, Guinea Pig, Horse, Human, Mouse, Rabbit, Rat
    Application: WB
    Product Size: 100 ul
    Price (USD): $289.00
  • TRIAL 
    ZNF835 Antibody - C-terminal region (ARP50336_P050) in Human HeLa using Western Blot

    ZNF835 Antibody - C-terminal region (ARP50336_P050)

    Protein Name:Zinc finger protein 835
    Catalog #:ARP50336_P050
    Type: pAb
    Reacts with: Cow, Dog, Guinea Pig, Horse, Human, Mouse, Rabbit, Rat
    Application: WB
    Product Size: 100 ul
    Price (USD): $289.00

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Showing 421 - 450 of 4219