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Transcription Factor Antibodies

Transcription factors are proteins that regulate gene expression by binding to DNA via one or more DNA-binding domains. This binding is achieved via a combination of electrostatic and van der waals forces and can occur at many closely-related sequences flanking different genes. Once bound to DNA directly or as part of a complex, they can promote or inhibit RNA polymerase recruitment, thereby acting as activators or repressors, respectively. Alternatively, transcription factors can act to recruit coactivators and corepressors or to catalyze histone acetylation and deacetylation. Transcription factors can function downstream of signaling cascades triggered by biological or environmental (ex. hypoxia, hyperthermia) stimuli to alter the expression of target genes. Ligand binding is necessary to activate some transcription factors as this can cause nuclear translocation and changes in the binding affinities for DNA and cofactors. During development, various stimuli can cause transcription factors to up- or down-regulate expression of specific genes at distinct time points to ensure proper development. Transcription factors can function as oncogenes or tumor suppressors and have thus been linked to various cancers. Accordingly, some therapeutic approaches in cancer therapy involve targeting transcription factor families[1].

1. Darnell JE Jr. 2002. Transcription factors as targets for cancer therapy. Nat Rev Cancer. Oct;2(10):740-9.

Transcription Factor Antibodies Top 20 Showcase

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Transcription Factors are involved in transcriptional regulation in the form of up regulation or down regulation acting as either repressors or activators of transcription. We have manufactured more than 3000 antibody products covering almost every known human and mouse transcription factors.

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Showing 421 - 450 of 4223
  • TRIAL 
    E2F2 Antibody - middle region (ARP31612_P050) in Human PANC1 using Western Blot

    E2F2 Antibody - middle region (ARP31612_P050)

    Protein Name:
    Catalog #:ARP31612_P050
    Type: pAb
    Reacts with: Cow, Dog, Guinea Pig, Human, Mouse, Pig, Rabbit, Rat, Zebrafish
    Application: WB
    Product Size: 100 ul
    Price (USD): $289.00
  • TRIAL 
    Prrx2 Antibody - middle region (ARP33008_P050) in Mouse Small Intestine using Western Blot

    Prrx2 Antibody - middle region (ARP33008_P050)

    Protein Name:Paired mesoderm homeobox protein 2
    Catalog #:ARP33008_P050
    Type: pAb
    Reacts with: Cow, Dog, Guinea Pig, Horse, Human, Mouse, Pig, Rabbit, Rat
    Application: WB
    Product Size: 100 ul
    Price (USD): $289.00
  • TRIAL 
    PPP2R3B antibody - N-terminal region (ARP42369_P050) in Human HeLa using Western Blot

    PPP2R3B antibody - N-terminal region (ARP42369_P050)

    Protein Name:Serine/threonine-protein phosphatase 2A regulatory subunit B'' subunit beta
    Catalog #:ARP42369_P050
    Type: pAb
    Reacts with: Human
    Application: WB
    Product Size: 100 ul
    Price (USD): $289.00
  • TRIAL 
    MTA1 Antibody - middle region (ARP35738_P050) in Human Thymus Tumor using Western Blot

    MTA1 Antibody - middle region (ARP35738_P050)

    Protein Name:Metastasis-associated protein MTA1
    Catalog #:ARP35738_P050
    Type: pAb
    Reacts with: Cow, Dog, Guinea Pig, Horse, Human, Mouse, Rabbit, Rat, Zebrafish
    Application: WB
    Product Size: 100 ul
    Price (USD): $289.00
  • TRIAL 
    Nr5a1 Antibody - C-terminal region (ARP37470_P050) in Mouse Lung using Western Blot

    Nr5a1 Antibody - C-terminal region (ARP37470_P050)

    Protein Name:Steroidogenic factor 1
    Catalog #:ARP37470_P050
    Type: pAb
    Reacts with: Cow, Guinea Pig, Horse, Human, Mouse, Rabbit, Rat, Sheep
    Application: WB
    Product Size: 100 ul
    Price (USD): $289.00
  • TRIAL 
    MYOT antibody - C-terminal region (ARP64117_P050) in Human Fetal liver using Western Blot

    MYOT antibody - C-terminal region (ARP64117_P050)

    Protein Name:Myotilin
    Catalog #:ARP64117_P050
    Type: pAb
    Reacts with: Cow, Dog, Guinea Pig, Horse, Human, Mouse, Rabbit, Rat
    Application: WB
    Product Size: 100 ul
    Price (USD): $289.00
  • TRIAL 
    Ube2g1 antibody - N-terminal region (ARP43014_P050) in Mouse Spleen using Western Blot

    Ube2g1 antibody - N-terminal region (ARP43014_P050)

    Protein Name:Ubiquitin-conjugating enzyme E2 G1
    Catalog #:ARP43014_P050
    Type: pAb
    Reacts with: Cow, Dog, Guinea Pig, Horse, Human, Mouse, Rabbit, Rat, Yeast, Zebrafish
    Application: WB
    Product Size: 100 ul
    Price (USD): $289.00
  • TRIAL 
    ZNF527 Antibody - N-terminal region (ARP39541_P050) in Human Placenta using Western Blot

    ZNF527 Antibody - N-terminal region (ARP39541_P050)

    Protein Name:Zinc finger protein 527
    Catalog #:ARP39541_P050
    Type: pAb
    Reacts with: Cow, Dog, Horse, Human, Mouse, Pig, Rabbit, Rat, Yeast
    Application: WB
    Product Size: 100 ul
    Price (USD): $289.00
  • TRIAL 
    Glra3 antibody - middle region (ARP35063_P050) in Mouse Small Intestine using Western Blot

    Glra3 antibody - middle region (ARP35063_P050)

    Protein Name:Glycine receptor subunit alpha-3
    Catalog #:ARP35063_P050
    Type: pAb
    Reacts with: Cow, Dog, Guinea Pig, Horse, Human, Mouse, Rabbit, Rat, Zebrafish
    Application: WB
    Product Size: 100 ul
    Price (USD): $289.00
  • TRIAL 
    VAX1 Antibody - N-terminal region (ARP34499_P050) in Human Ovary Tumor using Western Blot

    VAX1 Antibody - N-terminal region (ARP34499_P050)

    Protein Name:Ventral anterior homeobox 1
    Catalog #:ARP34499_P050
    Type: pAb
    Reacts with: Cow, Dog, Human, Mouse, Pig, Rat
    Application: WB
    Product Size: 100 ul
    Price (USD): $289.00
  • TRIAL 
    Hoxa1 Antibody - C-terminal region (ARP37061_P050) in Rat Small Intestine using Western Blot

    Hoxa1 Antibody - C-terminal region (ARP37061_P050)

    Protein Name:Homeobox protein Hox-A1
    Catalog #:ARP37061_P050
    Type: pAb
    Reacts with: Cow, Dog, Guinea Pig, Horse, Human, Mouse, Rabbit, Rat, Zebrafish
    Application: WB
    Product Size: 100 ul
    Price (USD): $289.00
  • TRIAL 
    SMS antibody - N-terminal region (ARP63040_P050) in Human MCF-7 using Western Blot

    SMS antibody - N-terminal region (ARP63040_P050)

    Protein Name:Spermine synthase
    Catalog #:ARP63040_P050
    Type: pAb
    Reacts with: Cow, Dog, Guinea Pig, Horse, Human, Mouse, Pig, Rabbit, Rat
    Application: WB
    Product Size: 100 ul
    Price (USD): $289.00
  • TRIAL 
    Rb1 Antibody - middle region (ARP33211_P050) in Mouse Heart using Western Blot

    Rb1 Antibody - middle region (ARP33211_P050)

    Protein Name:Retinoblastoma-associated protein
    Catalog #:ARP33211_P050
    Type: pAb
    Reacts with: Cow, Dog, Guinea Pig, Horse, Human, Mouse, Rabbit, Rat
    Application: WB
    Product Size: 100 ul
    Price (USD): $289.00
  • TRIAL 
    4930567H17Rik antibody - middle region (ARP31541_P050) in Mouse Kidney using Western Blot

    4930567H17Rik antibody - middle region (ARP31541_P050)

    Protein Name:Protein 4930567H17Rik Ensembl ENSMUSP00000090060
    Catalog #:ARP31541_P050
    Type: pAb
    Reacts with: Cow, Dog, Horse, Human, Mouse, Pig, Rabbit, Rat, Yeast, Zebrafish
    Application: WB
    Product Size: 100 ul
    Price (USD): $289.00
  • TRIAL 
    SSTR4 antibody - middle region (ARP33359_T100) in Human Jurkat using Western Blot

    SSTR4 antibody - middle region (ARP33359_T100)

    Protein Name:Somatostatin receptor type 4
    Catalog #:ARP33359_T100
    Type: pAb
    Reacts with: Mouse, Rabbit
    Application: WB
    Product Size: 100 ul
    Price (USD): $229.00

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Showing 421 - 450 of 4223