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Now Offering Over 85,203 Antibodies & 34,301 Antigens!

Transcription Factor Antibodies

Transcription factors are proteins that regulate gene expression by binding to DNA via one or more DNA-binding domains. This binding is achieved via a combination of electrostatic and van der waals forces and can occur at many closely-related sequences flanking different genes. Once bound to DNA directly or as part of a complex, they can promote or inhibit RNA polymerase recruitment, thereby acting as activators or repressors, respectively. Alternatively, transcription factors can act to recruit coactivators and corepressors or to catalyze histone acetylation and deacetylation. Transcription factors can function downstream of signaling cascades triggered by biological or environmental (ex. hypoxia, hyperthermia) stimuli to alter the expression of target genes. Ligand binding is necessary to activate some transcription factors as this can cause nuclear translocation and changes in the binding affinities for DNA and cofactors. During development, various stimuli can cause transcription factors to up- or down-regulate expression of specific genes at distinct time points to ensure proper development. Transcription factors can function as oncogenes or tumor suppressors and have thus been linked to various cancers. Accordingly, some therapeutic approaches in cancer therapy involve targeting transcription factor families[1].

1. Darnell JE Jr. 2002. Transcription factors as targets for cancer therapy. Nat Rev Cancer. Oct;2(10):740-9.

Transcription Factor Antibodies Top 20 Showcase

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Transcription Factors are involved in transcriptional regulation in the form of up regulation or down regulation acting as either repressors or activators of transcription. We have manufactured more than 3000 antibody products covering almost every known human and mouse transcription factors.

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Showing 421 - 450 of 3976
  Type Catalog # Product Product Images Price (USD)
  pAb ARP30619_P050 TFDP2 Antibody - C-terminal region (ARP30619_P050)
Reacts with
Dog, Horse, Human, Rat, Pig, Bovine, Mouse, Guinea pig, Rabbit
Application
WB
$289.00
  pAb ARP50929_P050 LOC730644 antibody - middle region (ARP50929_P050)
Reacts with
Human
Application
WB
$289.00
  pAb ARP47667_P050 RNF213 Antibody - N-terminal region (ARP47667_P050)
Reacts with
Human
Application
WB
$289.00
  pAb ARP34326_P050 LRRC14 Antibody - N-terminal region (ARP34326_P050)
Reacts with
Human
Application
WB
$289.00
  pAb ARP49814_P050 Mfsd11 antibody - C-terminal region (ARP49814_P050)
Reacts with
Rat, Dog, Bovine, Horse, Guinea pig, Human, Mouse, Rabbit
Application
WB
$289.00
  pAb ARP37945_P050 Naca-rs Antibody - C-terminal region (ARP37945_P050)
Reacts with
Mouse; Human
Application
WB
$289.00
  pAb ARP37463_P050 Ptges2 Antibody - N-terminal region (ARP37463_P050)
Reacts with
Mouse, Human, Rat
Application
WB
$289.00
  pAb ARP64147_P050 NTSR2 antibody - C-terminal region (ARP64147_P050)
Reacts with
Human, Yeast, Horse
Application
WB
$289.00
  pAb ARP32585_P050 OR13C5 Antibody - N-terminal region (ARP32585_P050)
Reacts with
Dog, Pig, Horse, Human, Rat, Bovine
Application
WB
$289.00
  pAb ARP33330_T100 SOX12 antibody - C-terminal region (ARP33330_T100)
Reacts with
Human, Rat, Dog, Horse, Pig, Mouse, Guinea pig
Application
WB
$229.00
  pAb ARP43698_P050 Dlg3 antibody - N-terminal region (ARP43698_P050)
Reacts with
Mouse, Bovine, Rabbit, Guinea pig, Human, Rat, Dog
Application
WB
$289.00
  pAb ARP57999_P050 GPS1 antibody - N-terminal region (ARP57999_P050)
Reacts with
Human
Application
WB
$289.00
  pAb ARP72332_P050 ZNF254 Antibody - middle region (ARP72332_P050)
Reacts with
Human, Bovine, Dog, Horse, Mouse, Rat
Application
WB
$289.00
  pAb ARP41316_P050 Wdr12 antibody - middle region (ARP41316_P050)
Reacts with
Human, Pig, Horse, Rabbit, Rat, Guinea pig, Bovine, Dog, Mouse, Zebrafish, Yeast
Application
WB
$289.00
  pAb ARP39094_P050 Cnot3 antibody - N-terminal region (ARP39094_P050)
Reacts with
Horse, Rabbit, Human, Rat, Bovine, Dog, Zebrafish, Pig, Guinea pig, Mouse, Goat, Yeast
Application
WB
$289.00
  pAb ARP67508_P050 FAM50A Antibody - C-terminal region (ARP67508_P050)
Reacts with
Rat, Bovine, Dog, Zebrafish, Horse, Rabbit, Pig, Mouse, Human, Guinea pig, Goat
Application
WB
$289.00
  pAb ARP38142_P050 Mxd1 antibody - C-terminal region (ARP38142_P050)
Reacts with
Human, Bovine, Rat, Pig, Guinea pig, Mouse, Horse, Rabbit, Dog
Application
WB
$289.00
  pAb ARP39608_P050 ZNF750 Antibody - N-terminal region (ARP39608_P050)
Reacts with
Bovine, Rat, Mouse, Dog, Zebrafish, Pig, Horse, Rabbit, Guinea pig, Human
Application
WB
$289.00
  pAb ARP32426_P050 DACH2 Antibody - C-terminal region (ARP32426_P050)
Reacts with
Human, Horse, Rabbit, Mouse, Dog, Rat, Bovine
Application
WB
$289.00
  pAb ARP35727_P050 MED21 antibody - C-terminal region (ARP35727_P050)
Reacts with
Pig, Horse, Rat, Dog, Human, Bovine, Guinea pig, Mouse
Application
WB
$289.00
  pAb ARP58031_P050 MID1 Antibody - N-terminal region (ARP58031_P050)
Reacts with
Human, Mouse, Bovine, Dog, Pig, Horse, Rat, Guinea pig, Rabbit, Zebrafish
Application
WB
$289.00
  pAb ARP37038_P050 Esr2 Antibody - N-terminal region (ARP37038_P050)
Reacts with
Dog, Mouse, Pig, Goat, Rat, Sheep, Bovine, Horse, Guinea pig, Human, Rabbit
Application
WB
$289.00
  pAb ARP63105_P050 Angpt1 antibody - C-terminal region (ARP63105_P050)
Reacts with
Human, Rat, Dog, Pig, Horse, Rabbit, Mouse, Bovine, Sheep, Guinea pig
Application
WB
$289.00
  pAb ARP71990_P050 WDR61 Antibody - N-terminal region (ARP71990_P050)
Reacts with
Human, Dog, Pig, Horse, Rat, Guinea pig, Rabbit, Bovine, Mouse
Application
WB
$289.00
  pAb ARP33492_P050 SF1 antibody - N-terminal region (ARP33492_P050)
Reacts with
Bovine, Horse, Zebrafish, Rabbit, Human, Mouse, Dog, Rat, Pig, Guinea pig, Yeast, Goat
Application
WB
$289.00
  pAb ARP32384_T100 SIRT2 antibody - N-terminal region (ARP32384_T100)
Reacts with
Rabbit, Human, Pig, Bovine, Horse, Mouse, Guinea pig, Dog, Yeast, Rat
Application
WB
$229.00
  pAb ARP34855_P050 ZFP2 antibody - N-terminal region (ARP34855_P050)
Reacts with
Human, Guinea pig
Application
WB
$289.00
  pAb ARP31546_P050 JDP2 antibody - N-terminal region (ARP31546_P050)
Reacts with
Horse, Human, Bovine, Rabbit, Guinea pig, Mouse, Rat, Dog
Application
WB
$289.00
  pAb ARP38337_P050 ZNF195 Antibody - N-terminal region (ARP38337_P050)
Reacts with
Human, Mouse, Rat, Horse, Rabbit, Dog
Application
WB
$289.00
  pAb ARP30932_P050 LYL1 Antibody - C-terminal region (ARP30932_P050)
Reacts with
Pig, Human
Application
WB
$289.00

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Showing 421 - 450 of 3976