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Now Offering Over 85,203 Antibodies & 34,301 Antigens!

Transcription Factor Antibodies

Transcription factors are proteins that regulate gene expression by binding to DNA via one or more DNA-binding domains. This binding is achieved via a combination of electrostatic and van der waals forces and can occur at many closely-related sequences flanking different genes. Once bound to DNA directly or as part of a complex, they can promote or inhibit RNA polymerase recruitment, thereby acting as activators or repressors, respectively. Alternatively, transcription factors can act to recruit coactivators and corepressors or to catalyze histone acetylation and deacetylation. Transcription factors can function downstream of signaling cascades triggered by biological or environmental (ex. hypoxia, hyperthermia) stimuli to alter the expression of target genes. Ligand binding is necessary to activate some transcription factors as this can cause nuclear translocation and changes in the binding affinities for DNA and cofactors. During development, various stimuli can cause transcription factors to up- or down-regulate expression of specific genes at distinct time points to ensure proper development. Transcription factors can function as oncogenes or tumor suppressors and have thus been linked to various cancers. Accordingly, some therapeutic approaches in cancer therapy involve targeting transcription factor families[1].

1. Darnell JE Jr. 2002. Transcription factors as targets for cancer therapy. Nat Rev Cancer. Oct;2(10):740-9.

Transcription Factor Antibodies Top 20 Showcase

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Transcription Factors are involved in transcriptional regulation in the form of up regulation or down regulation acting as either repressors or activators of transcription. We have manufactured more than 3000 antibody products covering almost every known human and mouse transcription factors.

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Showing 421 - 450 of 4181
  Type Catalog # Product Product Images Price (USD)
  pAb ARP70067_P050 CSRNP3 Antibody - N-terminal region (ARP70067_P050)
Reacts with
Cow, Dog, Guinea Pig, Horse, Human, Mouse, Rabbit, Rat, Zebrafish
Application
WB
$289.00
  pAb ARP41763_P050 GH1 antibody - C-terminal region (ARP41763_P050)
Reacts with
Cow, Goat, Horse, Human, Mouse, Pig, Rabbit, Rat, Sheep
Application
WB
$289.00
  pAb ARP72370_P050 TBX20 Antibody - C-terminal region (ARP72370_P050)
Reacts with
Cow, Dog, Guinea Pig, Horse, Human, Mouse, Rabbit, Rat, Zebrafish
Application
WB
$289.00
  pAb ARP32044_P050 NKX2-2 Antibody - N-terminal region (ARP32044_P050)
Reacts with
Cow, Dog, Guinea Pig, Horse, Human, Mouse, Pig, Rabbit, Rat, Sheep
Application
WB
$289.00
  pAb ARP51638_P050 MYCNOS antibody - N-terminal region (ARP51638_P050)
Reacts with
Human
Application
WB
$289.00
  pAb ARP34748_P050 BANP Antibody - N-terminal region (ARP34748_P050)
Reacts with
Cow, Dog, Guinea Pig, Horse, Human, Mouse, Rabbit, Rat, Yeast
Application
WB
$289.00
  pAb ARP37179_P050 Irf5 Antibody - middle region (ARP37179_P050)
Reacts with
Cow, Dog, Guinea Pig, Horse, Human, Mouse, Pig, Rabbit, Rat
Application
WB
$289.00
  pAb ARP63639_P050 CDC73 antibody - C-terminal region (ARP63639_P050)
Reacts with
Cow, Dog, Horse, Human, Mouse, Rabbit, Rat, Zebrafish
Application
WB
$289.00
  pAb ARP34591_P050 METTL3 antibody - C-terminal region (ARP34591_P050)
Reacts with
Cow, Dog, Goat, Guinea Pig, Horse, Human, Mouse, Rabbit, Rat, Zebrafish
Application
WB
$289.00
  pAb ARP34360_T100 MGC4618 antibody - N-terminal region (ARP34360_T100)
Reacts with
Dog, Guinea Pig, Horse, Human, Mouse, Rat
Application
WB
$229.00
  pAb ARP64882_P050 LTV1 antibody - C-terminal region (ARP64882_P050)
Reacts with
Cow, Dog, Guinea Pig, Horse, Human, Mouse, Rabbit, Rat
Application
WB
$289.00
  pAb ARP62050_P050 ACOT8 antibody - N-terminal region (ARP62050_P050)
Reacts with
Human
Application
WB
$289.00
  pAb ARP50344_P050 ZNF271 Antibody - middle region (ARP50344_P050)
Reacts with
Cow, Dog, Guinea Pig, Horse, Human, Mouse, Pig, Rabbit, Rat
Application
WB
$289.00
  pAb ARP34244_P050 CDC25A Antibody - N-terminal region (ARP34244_P050)
Reacts with
Cow, Dog, Guinea Pig, Horse, Human, Mouse, Rabbit, Rat
Application
WB
$289.00
  pAb ARP49151_P050 NAT8L antibody - C-terminal region (ARP49151_P050)
Reacts with
Cow, Dog, Guinea Pig, Horse, Human, Mouse, Rabbit, Rat, Zebrafish
Application
WB
$289.00
  pAb ARP30936_P050 MYB Antibody - C-terminal region (ARP30936_P050)
Reacts with
Dog, Human, Pig
Application
WB
$289.00
  pAb ARP54551_P050 LAMA4 antibody - C-terminal region (ARP54551_P050)
Reacts with
Human
Application
WB
$289.00
  pAb ARP72331_P050 ZNF680 Antibody - middle region (ARP72331_P050)
Reacts with
Human
Application
WB
$289.00
  pAb ARP33388_P050 SUPT6H Antibody - N-terminal region (ARP33388_P050)
Reacts with
Cow, Dog, Guinea Pig, Horse, Human, Mouse, Rabbit, Rat, Zebrafish
Application
WB
$289.00
  pAb ARP56510_P050 Rangap1 antibody - N-terminal region (ARP56510_P050)
Reacts with
Cow, Dog, Guinea Pig, Horse, Human, Mouse, Rabbit, Rat, Zebrafish
Application
WB
$289.00
  pAb ARP37943_P050 Foxk1 Antibody - middle region (ARP37943_P050)
Reacts with
Cow, Dog, Guinea Pig, Horse, Human, Mouse, Rabbit, Rat, Zebrafish
Application
WB
$289.00
  pAb ARP59927_P050 MRGPRX4 antibody - C-terminal region (ARP59927_P050)
Reacts with
Human, Mouse, Rabbit
Application
WB
$289.00
  pAb ARP42516_P050 Lrp2bp antibody - middle region (ARP42516_P050)
Reacts with
Cow, Dog, Guinea Pig, Horse, Human, Mouse, Pig, Rabbit, Rat, Zebrafish
Application
WB
$289.00
  pAb ARP56521_P050 Rfc1 Antibody - C-terminal region (ARP56521_P050)
Reacts with
Dog, Guinea Pig, Horse, Human, Mouse, Rabbit, Rat
Application
WB
$289.00
  pAb ARP39208_P050 Pparg Antibody - C-terminal region (ARP39208_P050)
Reacts with
Cow, Dog, Goat, Guinea Pig, Horse, Human, Mouse, Rabbit, Rat, Sheep, Zebrafish
Application
WB
$289.00
  pAb ARP42892_P050 Rab13 antibody - middle region (ARP42892_P050)
Reacts with
Cow, Dog, Guinea Pig, Horse, Human, Mouse, Rabbit, Rat, Zebrafish
Application
WB
$289.00
  pAb ARP33566_T100 ZNF426 antibody - N-terminal region (ARP33566_T100)
Reacts with
Human, Mouse, Rat
Application
WB
$229.00
  pAb ARP43824_P050 Slc31a1 antibody - N-terminal region (ARP43824_P050)
Reacts with
Dog, Horse, Human, Mouse, Rabbit, Rat
Application
WB
$289.00
  pAb ARP31580_P050 IRX2 Antibody - middle region (ARP31580_P050)
Reacts with
Dog, Guinea Pig, Horse, Human, Mouse, Rabbit, Rat
Application
WB
$289.00
  pAb ARP30574_P050 ID3 Antibody - N-terminal region (ARP30574_P050)
Reacts with
Cow, Dog, Guinea Pig, Horse, Human, Mouse, Pig, Rabbit, Rat, Sheep
Application
WB
$289.00

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Showing 421 - 450 of 4181