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Now Offering Over 85,203 Antibodies & 34,301 Antigens!

Transcription Factor Antibodies

Transcription factors are proteins that regulate gene expression by binding to DNA via one or more DNA-binding domains. This binding is achieved via a combination of electrostatic and van der waals forces and can occur at many closely-related sequences flanking different genes. Once bound to DNA directly or as part of a complex, they can promote or inhibit RNA polymerase recruitment, thereby acting as activators or repressors, respectively. Alternatively, transcription factors can act to recruit coactivators and corepressors or to catalyze histone acetylation and deacetylation. Transcription factors can function downstream of signaling cascades triggered by biological or environmental (ex. hypoxia, hyperthermia) stimuli to alter the expression of target genes. Ligand binding is necessary to activate some transcription factors as this can cause nuclear translocation and changes in the binding affinities for DNA and cofactors. During development, various stimuli can cause transcription factors to up- or down-regulate expression of specific genes at distinct time points to ensure proper development. Transcription factors can function as oncogenes or tumor suppressors and have thus been linked to various cancers. Accordingly, some therapeutic approaches in cancer therapy involve targeting transcription factor families[1].

1. Darnell JE Jr. 2002. Transcription factors as targets for cancer therapy. Nat Rev Cancer. Oct;2(10):740-9.

Transcription Factor Antibodies Top 20 Showcase

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Transcription Factors are involved in transcriptional regulation in the form of up regulation or down regulation acting as either repressors or activators of transcription. We have manufactured more than 3000 antibody products covering almost every known human and mouse transcription factors.

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Showing 421 - 450 of 3998
  Type Catalog # Product Product Images Price (USD)
  pAb ARP51215_P050 Fxn antibody - C-terminal region (ARP51215_P050)
Reacts with
Dog, Human, Rat, Horse, Rabbit, Guinea pig, Mouse, Bovine, Zebrafish, Yeast
Application
WB
$289.00
  pAb ARP50768_P050 ZNF678 Antibody - middle region (ARP50768_P050)
Reacts with
Human, Dog, Bovine, Mouse, Rat, Pig, Horse, Guinea pig, Rabbit
Application
WB
$289.00
  pAb ARP48592_P050 LOC640502 antibody - C-terminal region (ARP48592_P050)
Reacts with
Bovine, Rat, Dog, Pig, Horse, Rabbit, Guinea pig, Human, Mouse, Zebrafish
Application
WB
$289.00
  pAb ARP70162_P050 DUX4L9 Antibody - C-terminal region (ARP70162_P050)
Reacts with
Human
Application
WB
$289.00
  pAb ARP66349_P050 ESF1 Antibody - C-terminal region (ARP66349_P050)
Reacts with
Human, Pig, Rabbit, Rat, Dog, Horse
Application
WB
$289.00
  pAb ARP53673_P050 CABYR antibody - middle region (ARP53673_P050)
Reacts with
Human, Rat, Mouse, Rabbit, Pig, Dog, Horse, Bovine
Application
WB
$289.00
  pAb ARP50985_P050 ZNF679 Antibody - N-terminal region (ARP50985_P050)
Reacts with
Human
Application
WB
$289.00
  pAb ARP30913_P050 FOXO1 Antibody - C-terminal region (ARP30913_P050)
Reacts with
Pig, Dog, Horse, Human, Rabbit, Rat, Bovine, Guinea pig, Mouse
Application
WB
$289.00
  pAb ARP31431_P050 TCF7 Antibody - C-terminal region (ARP31431_P050)
Reacts with
Human
Application
WB
$289.00
  pAb ARP62420_P050 PPP6C antibody - N-terminal region (ARP62420_P050)
Reacts with
Yeast, Pig, Horse, Rabbit, Rat, Guinea pig, Dog, Human, Bovine, Zebrafish, Mouse, Goat
Application
WB
$289.00
  pAb ARP35900_P050 ZBTB7A Antibody - N-terminal region (ARP35900_P050)
Reacts with
Dog, Guinea pig, Human, Bovine, Mouse, Rat
Application
WB
$289.00
  pAb ARP60815_P050 Aacs antibody - N-terminal region (ARP60815_P050)
Reacts with
Bovine, Dog, Pig, Human, Horse, Rabbit, Rat, Guinea pig, Mouse, Zebrafish
Application
WB
$289.00
  pAb ARP32649_T100 AIRE antibody - N-terminal region (ARP32649_T100)
Reacts with
Human, Pig, Dog, Horse, Bovine, Rat
Application
WB
$229.00
  pAb ARP38016_P050 CHD2 Antibody - N-terminal region (ARP38016_P050)
Reacts with
Human, Bovine, Rat, Mouse, Pig, Horse, Rabbit, Dog, Zebrafish
Application
WB
$289.00
  pAb ARP42859_P050 Anxa13 Antibody - C-terminal region (ARP42859_P050)
Reacts with
Human, Rat, Horse, Mouse, Guinea pig, Dog, Rabbit, Bovine
Application
WB
$289.00
  pAb ARP64456_P050 GPRC6A antibody - C-terminal region (ARP64456_P050)
Reacts with
Human, Horse, Yeast, Dog
Application
WB
$289.00
  pAb ARP36587_P050 Anxa11 antibody - C-terminal region (ARP36587_P050)
Reacts with
Human, Mouse, Dog, Bovine, Pig, Horse, Rabbit, Rat, Guinea pig, Zebrafish
Application
WB
$289.00
  pAb ARP60158_P050 DAXX Antibody - C-terminal region (ARP60158_P050)
Reacts with
Human, Horse, Rat, Dog
Application
WB
$289.00
  pAb ARP38148_P050 Meis1 antibody - N-terminal region (ARP38148_P050)
Reacts with
Bovine, Rat, Human, Dog, Horse, Rabbit, Mouse, Guinea pig, Zebrafish
Application
WB
$289.00
  pAb ARP72147_P050 SOHLH2 Antibody - N-terminal region (ARP72147_P050)
Reacts with
Human, Dog, Rat, Guinea pig
Application
WB
$289.00
  pAb ARP47735_P050 Zfp367 Antibody - C-terminal region (ARP47735_P050)
Reacts with
Horse, Bovine, Rabbit, Pig, Mouse, Rat, Human, Dog, Guinea pig, Zebrafish
Application
WB
$289.00
  pAb ARP48771_P050 Tnik antibody - middle region (ARP48771_P050)
Reacts with
Yeast, Bovine, Dog, Human, Horse, Rabbit, Rat, Guinea pig, Mouse, Zebrafish
Application
WB
$289.00
  pAb ARP33388_P050 SUPT6H Antibody - N-terminal region (ARP33388_P050)
Reacts with
Human
Application
WB
$289.00
  pAb ARP51732_P050 EBF4 antibody - C-terminal region (ARP51732_P050)
Reacts with
Human, Bovine, Dog, Pig, Horse, Rabbit, Rat, Mouse, Guinea pig
Application
WB
$289.00
  pAb ARP37194_P050 Uncx Antibody - N-terminal region (ARP37194_P050)
Reacts with
Bovine, Rat, Mouse, Human, Dog, Pig, Zebrafish
Application
WB
$289.00
  pAb ARP64032_P050 RAP2A antibody - C-terminal region (ARP64032_P050)
Reacts with
Human, Sheep, Bovine, Horse, Mouse, Rat, Dog, Rabbit, Guinea pig, Zebrafish
Application
WB
$289.00
  pAb ARP31243_P050 VDR antibody - N-terminal region (ARP31243_P050)
Reacts with
Pig, Human, Dog, Horse, Rabbit, Rat, Mouse, Bovine, Guinea pig, Zebrafish
Application
WB
$289.00
  pAb ARP51028_P050 ZNF701 Antibody - middle region (ARP51028_P050)
Reacts with
Human, Mouse, Zebrafish, Bovine, Rat, Dog, Pig, Horse, Rabbit
Application
WB
$289.00
  pAb ARP50710_P050 Maf1 antibody - N-terminal region (ARP50710_P050)
Reacts with
Bovine, Mouse, Human, Pig, Horse, Rat, Guinea pig
Application
WB
$289.00
  pAb ARP53574_P050 AURKA Antibody - middle region (ARP53574_P050)
Reacts with
Human, Bovine, Dog, Horse, Mouse, Rabbit, Rat, Guinea pig, Zebrafish, Sheep
Application
WB
$289.00

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Showing 421 - 450 of 3998