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Now Offering Over 85,203 Antibodies & 34,301 Antigens!

Transcription Factor Antibodies

Transcription factors are proteins that regulate gene expression by binding to DNA via one or more DNA-binding domains. This binding is achieved via a combination of electrostatic and van der waals forces and can occur at many closely-related sequences flanking different genes. Once bound to DNA directly or as part of a complex, they can promote or inhibit RNA polymerase recruitment, thereby acting as activators or repressors, respectively. Alternatively, transcription factors can act to recruit coactivators and corepressors or to catalyze histone acetylation and deacetylation. Transcription factors can function downstream of signaling cascades triggered by biological or environmental (ex. hypoxia, hyperthermia) stimuli to alter the expression of target genes. Ligand binding is necessary to activate some transcription factors as this can cause nuclear translocation and changes in the binding affinities for DNA and cofactors. During development, various stimuli can cause transcription factors to up- or down-regulate expression of specific genes at distinct time points to ensure proper development. Transcription factors can function as oncogenes or tumor suppressors and have thus been linked to various cancers. Accordingly, some therapeutic approaches in cancer therapy involve targeting transcription factor families[1].

1. Darnell JE Jr. 2002. Transcription factors as targets for cancer therapy. Nat Rev Cancer. Oct;2(10):740-9.

Transcription Factor Antibodies Top 20 Showcase

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Transcription Factors are involved in transcriptional regulation in the form of up regulation or down regulation acting as either repressors or activators of transcription. We have manufactured more than 3000 antibody products covering almost every known human and mouse transcription factors.

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Showing 421 - 450 of 3998
  Type Catalog # Product Product Images Price (USD)
  pAb ARP70505_P050 GREB1 Antibody - N-terminal region (ARP70505_P050)
Reacts with
Mouse, Bovine, Dog, Rat, Pig, Horse, Human, Rabbit, Guinea pig, Zebrafish
Application
WB
$289.00
  pAb ARP41435_P050 Hao2 antibody - middle region (ARP41435_P050)
Reacts with
Horse, Human, Dog, Pig, Rat, Mouse, Bovine
Application
WB
$289.00
  pAb ARP34444_P050 Trim35 Antibody - middle region (ARP34444_P050)
Reacts with
Dog, Bovine, Horse, Rabbit, Human, Pig, Rat, Guinea pig, Mouse
Application
WB
$289.00
  pAb ARP39275_P050 Hoxb9 antibody - C-terminal region (ARP39275_P050)
Reacts with
Pig, Bovine, Horse, Rabbit, Dog, Rat, Guinea pig, Mouse, Human, Zebrafish
Application
WB
$289.00
  pAb ARP36400_P050 Ddx20 Antibody - middle region (ARP36400_P050)
Reacts with
Human, Rat, Pig, Horse, Mouse, Bovine, Dog, Guinea pig
Application
WB
$289.00
  pAb ARP38924_P050 ZHX1 antibody - N-terminal region (ARP38924_P050)
Reacts with
Human, Horse, Rabbit, Dog, Pig, Bovine, Rat, Mouse
Application
WB
$289.00
  pAb ARP32266_P050 EWSR1 Antibody - C-terminal region (ARP32266_P050)
Reacts with
Bovine, Human, Rat, Dog, Pig, Horse, Rabbit, Mouse, Zebrafish, Guinea pig
Application
WB
$289.00
  pAb ARP42892_P050 Rab13 antibody - middle region (ARP42892_P050)
Reacts with
Human, Mouse, Dog, Pig, Horse, Rabbit, Rat, Guinea pig, Bovine, Zebrafish
Application
WB
$289.00
  pAb ARP32633_P050 Hnf4g Antibody - middle region (ARP32633_P050)
Reacts with
Bovine, Human, Dog, Rabbit, Guinea pig, Rat, Mouse, Horse
Application
WB
$289.00
  pAb ARP51638_P050 MYCNOS antibody - N-terminal region (ARP51638_P050)
Reacts with
Human
Application
WB
$289.00
  pAb ARP40148_P050 Tbx18 Antibody - N-terminal region (ARP40148_P050)
Reacts with
Mouse, Rat, Pig, Bovine, Dog, Horse, Rabbit, Guinea pig, Human
Application
WB
$289.00
  pAb ARP37038_P050 Esr2 Antibody - N-terminal region (ARP37038_P050)
Reacts with
Dog, Mouse, Pig, Goat, Rat, Sheep, Bovine, Horse, Guinea pig, Human, Rabbit
Application
WB
$289.00
  pAb ARP63639_P050 CDC73 antibody - C-terminal region (ARP63639_P050)
Reacts with
Dog, Bovine, Rat, Horse, Rabbit, Human, Mouse, Zebrafish
Application
WB
$289.00
  pAb ARP58193_P050 RORC Antibody - N-terminal region (ARP58193_P050)
Reacts with
Human, Pig, Bovine, Dog, Rabbit, Mouse, Horse, Guinea pig
Application
WB
$289.00
  pAb ARP34591_P050 METTL3 antibody - C-terminal region (ARP34591_P050)
Reacts with
Bovine, Human, Dog, Pig, Horse, Goat, Rabbit, Mouse, Rat, Guinea pig, Zebrafish
Application
WB
$289.00
  pAb ARP64882_P050 LTV1 antibody - C-terminal region (ARP64882_P050)
Reacts with
Horse, Human, Dog, Rabbit, Rat, Bovine, Guinea pig, Mouse
Application
WB
$289.00
  pAb ARP72093_P050 ZNF772 Antibody - middle region (ARP72093_P050)
Reacts with
Human, Horse
Application
WB
$289.00
  pAb ARP62050_P050 ACOT8 antibody - N-terminal region (ARP62050_P050)
Reacts with
Human
Application
WB
$289.00
  pAb ARP34244_P050 CDC25A Antibody - N-terminal region (ARP34244_P050)
Reacts with
Bovine, Human, Dog, Horse, Rabbit, Rat, Guinea pig, Mouse
Application
WB
$289.00
  pAb ARP49151_P050 NAT8L antibody - C-terminal region (ARP49151_P050)
Reacts with
Rat, Bovine, Dog, Pig, Horse, Rabbit, Guinea pig, Mouse, Human, Zebrafish
Application
WB
$289.00
  pAb ARP30967_P050 WT1 Antibody - N-terminal region (ARP30967_P050)
Reacts with
Mouse, Rat, Dog, Pig, Rabbit, Human, Zebrafish
Application
WB
$289.00
  pAb ARP54551_P050 LAMA4 antibody - C-terminal region (ARP54551_P050)
Reacts with
Human
Application
WB
$289.00
  pAb ARP38998_P050 SETDB1 Antibody - N-terminal region (ARP38998_P050)
Reacts with
Human, Dog, Horse, Bovine, Rat, Guinea pig, Rabbit
Application
WB
$289.00
  pAb ARP34818_P050 KLHL3 Antibody - N-terminal region (ARP34818_P050)
Reacts with
Human, Mouse, Rat, Bovine, Dog, Pig, Horse, Guinea pig, Rabbit, Yeast, Zebrafish
Application
WB
$289.00
  pAb ARP56510_P050 Rangap1 antibody - N-terminal region (ARP56510_P050)
Reacts with
Bovine, Rat, Dog, Horse, Rabbit, Guinea pig, Human, Mouse, Zebrafish
Application
WB
$289.00
  pAb ARP50860_P050 ZBTB41 Antibody - C-terminal region (ARP50860_P050)
Reacts with
Mouse, Dog, Horse, Rabbit, Guinea pig, Human, Rat, Bovine
Application
WB
$289.00
  pAb ARP37587_P050 Radil Antibody - C-terminal region (ARP37587_P050)
Reacts with
Mouse, Rat, Guinea pig
Application
WB
$289.00
  pAb ARP59927_P050 MRGPRX4 antibody - C-terminal region (ARP59927_P050)
Reacts with
Human, Rabbit, Mouse
Application
WB
$289.00
  pAb ARP70067_P050 CSRNP3 Antibody - N-terminal region (ARP70067_P050)
Reacts with
Rat, Human, Pig, Horse, Rabbit, Guinea pig, Dog, Mouse, Bovine, Zebrafish
Application
WB
$289.00
  pAb ARP42516_P050 Lrp2bp antibody - middle region (ARP42516_P050)
Reacts with
Human, Bovine, Dog, Pig, Horse, Rabbit, Rat, Mouse, Guinea pig, Zebrafish
Application
WB
$289.00

Page of 134

Showing 421 - 450 of 3998