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Now Offering Over 85,203 Antibodies & 34,301 Antigens!

Transcription Factor Antibodies

Transcription factors are proteins that regulate gene expression by binding to DNA via one or more DNA-binding domains. This binding is achieved via a combination of electrostatic and van der waals forces and can occur at many closely-related sequences flanking different genes. Once bound to DNA directly or as part of a complex, they can promote or inhibit RNA polymerase recruitment, thereby acting as activators or repressors, respectively. Alternatively, transcription factors can act to recruit coactivators and corepressors or to catalyze histone acetylation and deacetylation. Transcription factors can function downstream of signaling cascades triggered by biological or environmental (ex. hypoxia, hyperthermia) stimuli to alter the expression of target genes. Ligand binding is necessary to activate some transcription factors as this can cause nuclear translocation and changes in the binding affinities for DNA and cofactors. During development, various stimuli can cause transcription factors to up- or down-regulate expression of specific genes at distinct time points to ensure proper development. Transcription factors can function as oncogenes or tumor suppressors and have thus been linked to various cancers. Accordingly, some therapeutic approaches in cancer therapy involve targeting transcription factor families[1].

1. Darnell JE Jr. 2002. Transcription factors as targets for cancer therapy. Nat Rev Cancer. Oct;2(10):740-9.

Transcription Factor Antibodies Top 20 Showcase

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Transcription Factors are involved in transcriptional regulation in the form of up regulation or down regulation acting as either repressors or activators of transcription. We have manufactured more than 3000 antibody products covering almost every known human and mouse transcription factors.

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Showing 421 - 450 of 3998
  Type Catalog # Product Product Images Price (USD)
  pAb ARP72325_P050 ZNF90 Antibody - C-terminal region (ARP72325_P050)
Reacts with
Human
Application
WB
$289.00
  pAb ARP48661_P050 Oxsr1 antibody - middle region (ARP48661_P050)
Reacts with
Human, Rat, Dog, Bovine, Pig, Horse, Guinea pig, Mouse, Zebrafish, Rabbit, Yeast
Application
WB
$289.00
  pAb ARP72499_P050 HEY1 Antibody - N-terminal region (ARP72499_P050)
Reacts with
Human, Zebrafish, Sheep, Rat, Bovine, Pig, Horse, Dog, Rabbit, Guinea pig, Mouse
Application
WB
$289.00
  pAb ARP30727_P050 NPY2R Antibody - N-terminal region (ARP30727_P050)
Reacts with
Bovine, Rabbit, Pig, Human, Mouse, Rat, Horse, Guinea pig
Application
WB
$289.00
  pAb ARP51800_P050 C4orf46 antibody - N-terminal region (ARP51800_P050)
Reacts with
Human, Horse
Application
WB
$289.00
  pAb ARP34488_P050 NKX6-3 Antibody - C-terminal region (ARP34488_P050)
Reacts with
Human, Rat, Rabbit, Mouse
Application
WB
$289.00
  pAb ARP31670_P050 Ng35 antibody - middle region (ARP31670_P050)
Reacts with
Pig, Rat, Bovine, Guinea pig, Dog, Mouse, Human, Yeast
Application
WB
$289.00
  pAb ARP37446_P050 Sp7 Antibody - N-terminal region (ARP37446_P050)
Reacts with
Mouse, Bovine, Pig, Horse, Human, Rat, Dog, Rabbit, Guinea pig
Application
WB
$289.00
  pAb ARP39495_P050 HOXA11 Antibody - C-terminal region (ARP39495_P050)
Reacts with
Mouse, Zebrafish, Sheep, Bovine, Dog, Horse, Rabbit, Rat, Guinea pig, Human
Application
WB
$289.00
  pAb ARP57250_P050 ALLC antibody - N-terminal region (ARP57250_P050)
Reacts with
Human, Rabbit, Dog, Horse, Bovine, Pig, Rat
Application
WB
$289.00
  pAb ARP41307_P050 Wdr5 antibody - C-terminal region (ARP41307_P050)
Reacts with
Dog, Pig, Mouse, Horse, Bovine, Rat, Guinea pig, Human, Zebrafish
Application
WB
$289.00
  pAb ARP38943_P050 Dpf3 antibody - N-terminal region (ARP38943_P050)
Reacts with
Mouse, Pig, Horse, Rabbit, Guinea pig, Human, Rat, Zebrafish
Application
WB
$289.00
  pAb ARP39632_P050 ZNF746 Antibody - N-terminal region (ARP39632_P050)
Reacts with
Human, Rat, Bovine, Dog, Pig, Horse, Rabbit, Guinea pig, Mouse
Application
WB
$289.00
  pAb ARP35741_P050 Lrrfip1 Antibody - middle region (ARP35741_P050)
Reacts with
Mouse, Bovine, Human, Dog, Horse, Rabbit, Guinea pig, Rat, Zebrafish
Application
WB
$289.00
  pAb ARP38119_P050 Hpcal1 antibody - C-terminal region (ARP38119_P050)
Reacts with
Sheep, Human, Horse, Rabbit, Rat, Guinea pig, Dog, Bovine, Mouse, Zebrafish
Application
WB
$289.00
  pAb ARP32244_P050 ZNF48 Antibody - C-terminal region (ARP32244_P050)
Reacts with
Human, Rabbit, Bovine, Pig, Goat, Guinea pig, Dog, Rat, Mouse
Application
WB
$289.00
  pAb ARP32803_P050 DBI antibody - N-terminal region (ARP32803_P050)
Reacts with
Human
Application
WB
$289.00
  pAb ARP36812_P050 Mxi1 Antibody - N-terminal region (ARP36812_P050)
Reacts with
Dog, Rat, Pig, Bovine, Mouse, Horse, Guinea pig, Human
Application
WB
$289.00
  pAb ARP38333_P050 ZNF8 Antibody - N-terminal region (ARP38333_P050)
Reacts with
Human, Bovine, Dog, Pig, Horse, Rat, Mouse, Rabbit
Application
WB
$289.00
  pAb ARP63041_P050 Sms antibody - middle region (ARP63041_P050)
Reacts with
Human, Mouse, Pig, Horse, Rabbit, Rat, Guinea pig, Bovine, Dog, Zebrafish
Application
WB
$289.00
  pAb ARP32256_T100 NR2F6 antibody - N-terminal region (ARP32256_T100)
Reacts with
Human, Dog, Bovine, Pig, Guinea pig, Rat, Mouse
Application
WB
$229.00
  pAb ARP32628_P050 NR4A1 antibody - C-terminal region (ARP32628_P050)
Reacts with
Human, Horse, Rabbit, Rat, Dog, Mouse, Guinea pig, Bovine, Zebrafish
Application
WB
$289.00
  pAb ARP47709_P050 ZSCAN21 Antibody - middle region (ARP47709_P050)
Reacts with
Mouse, Pig, Human, Dog, Horse, Guinea pig, Rat, Bovine, Rabbit
Application
WB
$289.00
  pAb ARP64823_P050 CD96 antibody - C-terminal region (ARP64823_P050)
Reacts with
Human, Guinea pig
Application
WB
$289.00
  pAb ARP69130_P050 MEX3A Antibody - N-terminal region (ARP69130_P050)
Reacts with
Human, Rat, Bovine, Dog, Pig, Horse, Rabbit, Mouse, Guinea pig
Application
WB
$289.00
  pAb ARP39256_P050 LIMA1 antibody - C-terminal region (ARP39256_P050)
Reacts with
Human, Bovine, Rat, Horse, Rabbit, Dog, Mouse, Pig, Yeast, Zebrafish
Application
WB
$289.00
  pAb ARP40566_P050 HNRNPF antibody - C-terminal region (ARP40566_P050)
Reacts with
Human, Dog, Pig, Horse, Rabbit, Rat, Guinea pig, Mouse, Bovine
Application
WB
$289.00
  pAb ARP72898_P050 SMARCD3 Antibody - C-terminal region (ARP72898_P050)
Reacts with
Zebrafish, Human, Dog, Pig, Horse, Rabbit, Rat, Guinea pig, Bovine, Mouse
Application
WB
$289.00
  pAb ARP30936_P050 MYB Antibody - C-terminal region (ARP30936_P050)
Reacts with
Human, Pig, Dog
Application
WB
$289.00
  pAb ARP54405_P050 C10orf132 antibody - N-terminal region (ARP54405_P050)
Reacts with
Rat, Dog, Pig, Bovine, Human, Mouse, Horse, Rabbit, Zebrafish
Application
WB
$289.00

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Showing 421 - 450 of 3998