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Now Offering Over 85,203 Antibodies & 34,301 Antigens!

Transcription Factor Antibodies

Transcription factors are proteins that regulate gene expression by binding to DNA via one or more DNA-binding domains. This binding is achieved via a combination of electrostatic and van der waals forces and can occur at many closely-related sequences flanking different genes. Once bound to DNA directly or as part of a complex, they can promote or inhibit RNA polymerase recruitment, thereby acting as activators or repressors, respectively. Alternatively, transcription factors can act to recruit coactivators and corepressors or to catalyze histone acetylation and deacetylation. Transcription factors can function downstream of signaling cascades triggered by biological or environmental (ex. hypoxia, hyperthermia) stimuli to alter the expression of target genes. Ligand binding is necessary to activate some transcription factors as this can cause nuclear translocation and changes in the binding affinities for DNA and cofactors. During development, various stimuli can cause transcription factors to up- or down-regulate expression of specific genes at distinct time points to ensure proper development. Transcription factors can function as oncogenes or tumor suppressors and have thus been linked to various cancers. Accordingly, some therapeutic approaches in cancer therapy involve targeting transcription factor families[1].

1. Darnell JE Jr. 2002. Transcription factors as targets for cancer therapy. Nat Rev Cancer. Oct;2(10):740-9.

Transcription Factor Antibodies Top 20 Showcase

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Transcription Factors are involved in transcriptional regulation in the form of up regulation or down regulation acting as either repressors or activators of transcription. We have manufactured more than 3000 antibody products covering almost every known human and mouse transcription factors.

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Showing 421 - 450 of 3998
  Type Catalog # Product Product Images Price (USD)
  pAb ARP35894_P050 ZFYVE26 Antibody - N-terminal region (ARP35894_P050)
Reacts with
Human, Rabbit, Rat, Bovine, Dog, Pig, Horse, Guinea pig, Mouse
Application
WB
$289.00
  pAb ARP59775_P050 Opn1mw antibody - C-terminal region (ARP59775_P050)
Reacts with
Rat, Mouse, Human, Horse, Rabbit, Dog, Guinea pig, Goat, Bovine
Application
WB
$289.00
  pAb ARP37948_P050 Vgll1 Antibody - C-terminal region (ARP37948_P050)
Reacts with
Mouse
Application
WB
$289.00
  pAb ARP64419_P050 KRT6A antibody - middle region (ARP64419_P050)
Reacts with
Human, Rat, Bovine, Pig, Horse, Rabbit, Mouse, Sheep, Dog
Application
WB
$289.00
  pAb ARP36411_P050 Dhx38 antibody - N-terminal region (ARP36411_P050)
Reacts with
Human, Rat, Dog, Bovine, Horse, Rabbit, Guinea pig, Mouse, Zebrafish
Application
WB
$289.00
  pAb ARP39065_P050 NFYC Antibody - N-terminal region (ARP39065_P050)
Reacts with
Mouse, Zebrafish, Human, Dog, Pig, Horse, Rabbit, Rat, Guinea pig, Bovine
Application
WB
$289.00
  pAb ARP37828_P050 Zfp872 antibody - middle region (ARP37828_P050)
Reacts with
Mouse, Human, Pig, Horse, Guinea pig, Rat, Zebrafish, Bovine
Application
WB
$289.00
  pAb ARP51222_P050 Ints12 Antibody - C-terminal region (ARP51222_P050)
Reacts with
Dog, Horse, Rabbit, Rat, Guinea pig, Bovine, Human, Mouse, Zebrafish
Application
WB
$289.00
  pAb ARP47718_P050 Zkscan6 Antibody - C-terminal region (ARP47718_P050)
Reacts with
Human, Dog, Bovine, Pig, Horse, Rabbit, Rat, Mouse, Zebrafish
Application
WB
$289.00
  pAb ARP48260_P050 ERH antibody - middle region (ARP48260_P050)
Reacts with
Rat, Pig, Horse, Rabbit, Mouse, Guinea pig, Dog, Human, Bovine, Zebrafish
Application
WB
$289.00
  pAb ARP51129_P050 LOC652119 Antibody - N-terminal region (ARP51129_P050)
Reacts with
Human
Application
WB
$289.00
  pAb ARP33371_P050 BRD3 Antibody - middle region (ARP33371_P050)
Reacts with
Human
Application
WB
$289.00
  pAb ARP39112_P050 NT5C antibody - C-terminal region (ARP39112_P050)
Reacts with
Human
Application
IHC, WB
$289.00
  pAb ARP33529_P050 ZSCAN22 Antibody - N-terminal region (ARP33529_P050)
Reacts with
Human, Rat, Rabbit, Mouse, Bovine, Dog, Horse, Guinea pig
Application
WB
$289.00
  pAb ARP32237_P050 ZNF280B antibody - N-terminal region (ARP32237_P050)
Reacts with
Human, Bovine, Pig, Rat, Rabbit, Goat, Dog
Application
WB
$289.00
  pAb ARP37256_P050 Hdac7 Antibody - N-terminal region (ARP37256_P050)
Reacts with
Mouse, Rat, Bovine, Guinea pig, Human, Dog, Horse
Application
WB
$289.00
  pAb ARP64048_P050 PRKAG3 antibody - N-terminal region (ARP64048_P050)
Reacts with
Human
Application
WB
$289.00
  pAb ARP31114_P050 NFE2L1 antibody - C-terminal region (ARP31114_P050)
Reacts with
Mouse, Bovine, Human, Rat, Dog, Rabbit
Application
WB
$289.00
  pAb ARP32232_P050 SPIC antibody - C-terminal region (ARP32232_P050)
Reacts with
Pig, Rat, Dog, Horse, Rabbit, Human, Bovine, Mouse, Guinea pig, Zebrafish
Application
WB
$289.00
  pAb ARP47540_P050 NOBOX Antibody - N-terminal region (ARP47540_P050)
Reacts with
Human, Rabbit
Application
WB
$289.00
  pAb ARP31305_P050 Lmo1 Antibody - C-terminal region (ARP31305_P050)
Reacts with
Pig, Dog, Human, Horse, Rat, Guinea pig, Mouse, Rabbit, Bovine, Zebrafish
Application
WB
$289.00
  pAb ARP61366_P050 CYSLTR1 antibody - C-terminal region (ARP61366_P050)
Reacts with
Human, Bovine, Horse, Dog, Guinea pig, Rabbit
Application
WB
$289.00
  pAb ARP61895_P050 Pkn2 Antibody - C-terminal region (ARP61895_P050)
Reacts with
Human, Zebrafish, Rat, Bovine, Dog, Pig, Horse, Rabbit, Mouse, Guinea pig, Yeast
Application
WB
$289.00
  pAb ARP31591_P050 DDIT3 Antibody - N-terminal region (ARP31591_P050)
Reacts with
Horse, Human, Guinea pig, Rabbit, Rat, Mouse, Dog, Goat, Bovine, Sheep
Application
WB
$289.00
  pAb ARP40086_P050 RFX4 antibody - N-terminal region (ARP40086_P050)
Reacts with
Zebrafish, Human, Mouse, Dog, Horse, Rabbit, Rat, Guinea pig, Yeast
Application
WB
$289.00
  pAb ARP62628_P050 KANK2 antibody - C-terminal region (ARP62628_P050)
Reacts with
Human, Dog, Bovine, Horse, Rat, Pig, Guinea pig, Mouse, Rabbit
Application
WB
$289.00
  pAb ARP50946_P050 YBX1 Antibody - C-terminal region (ARP50946_P050)
Reacts with
Mouse, Rat, Pig, Rabbit, Dog, Human, Sheep, Guinea pig, Bovine, Horse
Application
WB
$289.00
  pAb ARP36046_P050 ZNF671 Antibody - C-terminal region (ARP36046_P050)
Reacts with
Human, Horse, Pig, Bovine, Mouse, Dog, Rabbit, Rat, Guinea pig
Application
WB
$289.00
  pAb ARP61755_P050 Tbce antibody - N-terminal region (ARP61755_P050)
Reacts with
Human, Mouse, Pig, Rabbit, Guinea pig, Horse, Bovine, Rat, Dog, Zebrafish, Yeast
Application
WB
$289.00
  pAb ARP64564_P050 DRP2 antibody - middle region (ARP64564_P050)
Reacts with
Human, Horse, Rabbit, Guinea pig, Bovine, Dog, Rat, Mouse
Application
WB
$289.00

Page of 134

Showing 421 - 450 of 3998