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Now Offering Over 85,203 Antibodies & 34,301 Antigens!

Transcription Factor Antibodies

Transcription factors are proteins that regulate gene expression by binding to DNA via one or more DNA-binding domains. This binding is achieved via a combination of electrostatic and van der waals forces and can occur at many closely-related sequences flanking different genes. Once bound to DNA directly or as part of a complex, they can promote or inhibit RNA polymerase recruitment, thereby acting as activators or repressors, respectively. Alternatively, transcription factors can act to recruit coactivators and corepressors or to catalyze histone acetylation and deacetylation. Transcription factors can function downstream of signaling cascades triggered by biological or environmental (ex. hypoxia, hyperthermia) stimuli to alter the expression of target genes. Ligand binding is necessary to activate some transcription factors as this can cause nuclear translocation and changes in the binding affinities for DNA and cofactors. During development, various stimuli can cause transcription factors to up- or down-regulate expression of specific genes at distinct time points to ensure proper development. Transcription factors can function as oncogenes or tumor suppressors and have thus been linked to various cancers. Accordingly, some therapeutic approaches in cancer therapy involve targeting transcription factor families[1].

1. Darnell JE Jr. 2002. Transcription factors as targets for cancer therapy. Nat Rev Cancer. Oct;2(10):740-9.

Transcription Factor Antibodies Top 20 Showcase

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Transcription Factors are involved in transcriptional regulation in the form of up regulation or down regulation acting as either repressors or activators of transcription. We have manufactured more than 3000 antibody products covering almost every known human and mouse transcription factors.

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Showing 421 - 450 of 3976
  Type Catalog # Product Product Images Price (USD)
  pAb ARP30108_P050 Tsc22d4 Antibody - N-terminal region (ARP30108_P050)
Reacts with
Rat, Human, Dog, Rabbit, Guinea pig, Bovine, Mouse, Horse
Application
WB
$289.00
  pAb ARP61198_P050 GET4 antibody - N-terminal region (ARP61198_P050)
Reacts with
Human, Mouse, Rat, Dog, Guinea pig, Horse, Bovine, Zebrafish
Application
WB
$289.00
  pAb ARP72092_P050 ZNF772 Antibody - N-terminal region (ARP72092_P050)
Reacts with
Human, Horse, Rat, Pig, Zebrafish, Rabbit, Dog, Bovine, Mouse, Guinea pig
Application
WB
$289.00
  pAb ARP50659_P050 ZNF20 Antibody - C-terminal region (ARP50659_P050)
Reacts with
Mouse, Human
Application
WB
$289.00
  pAb ARP30665_P050 CHAT antibody - C-terminal region (ARP30665_P050)
Reacts with
Human, Dog, Horse, Pig
Application
WB
$289.00
  pAb ARP32044_P050 NKX2-2 Antibody - N-terminal region (ARP32044_P050)
Reacts with
Bovine, Dog, Horse, Rabbit, Pig, Human, Rat, Sheep, Mouse, Guinea pig
Application
WB
$289.00
  pAb ARP62985_P050 CD2 antibody - C-terminal region (ARP62985_P050)
Reacts with
Human, Pig, Dog, Horse, Bovine, Sheep, Rabbit
Application
WB
$289.00
  pAb ARP36809_P050 Dbx1 Antibody - C-terminal region (ARP36809_P050)
Reacts with
Mouse, Rat, Dog, Horse, Rabbit, Pig, Yeast, Human, Guinea pig, Bovine
Application
WB
$289.00
  pAb ARP38330_P050 ZNF586 Antibody - middle region (ARP38330_P050)
Reacts with
Human, Dog, Horse, Bovine, Pig, Rabbit, Rat, Mouse
Application
WB
$289.00
  pAb ARP62354_P050 Pitpnc1 antibody - middle region (ARP62354_P050)
Reacts with
Human, Pig, Rat, Dog, Horse, Rabbit, Guinea pig, Mouse, Zebrafish
Application
WB
$289.00
  pAb ARP64778_P050 MMP28 antibody - C-terminal region (ARP64778_P050)
Reacts with
Human, Horse, Dog, Bovine
Application
WB
$289.00
  pAb ARP35960_P050 MESP1 antibody - C-terminal region (ARP35960_P050)
Reacts with
Human, Bovine, Horse
Application
WB
$289.00
  pAb ARP69905_P050 ZBTB34 Antibody - N-terminal region (ARP69905_P050)
Reacts with
Rabbit, Rat, Guinea pig, Human, Mouse, Bovine, Horse, Dog
Application
WB
$289.00
  pAb ARP42116_P050 Timp2 antibody - C-terminal region (ARP42116_P050)
Reacts with
Mouse, Human, Pig, Sheep, Bovine, Dog, Horse, Rat, Rabbit, Guinea pig, Zebrafish
Application
WB
$289.00
  pAb ARP72898_P050 SMARCD3 Antibody - C-terminal region (ARP72898_P050)
Reacts with
Zebrafish, Human, Dog, Pig, Horse, Rabbit, Rat, Guinea pig, Bovine, Mouse
Application
WB
$289.00
  pAb ARP45630_P050 Rorb antibody - N-terminal region (ARP45630_P050)
Reacts with
Zebrafish, Sheep, Human, Goat, Rat, Bovine, Dog, Pig, Horse, Rabbit, Guinea pig, Mouse, Yeast
Application
WB
$289.00
  pAb ARP34179_P050 PAX8 Antibody - C-terminal region (ARP34179_P050)
Reacts with
Bovine, Horse, Pig, Dog, Human, Mouse, Rat, Guinea pig
Application
WB
$289.00
  pAb ARP41879_P050 KLK3 antibody - middle region (ARP41879_P050)
Reacts with
Human, Mouse, Rat, Dog
Application
WB
$289.00
  pAb ARP37439_P050 Vsx1 Antibody - C-terminal region (ARP37439_P050)
Reacts with
Mouse, Rat
Application
WB
$289.00
  pAb ARP39531_P050 NR1I2 Antibody - N-terminal region (ARP39531_P050)
Reacts with
Human
Application
WB
$289.00
  pAb ARP64105_P050 PEX13 antibody - C-terminal region (ARP64105_P050)
Reacts with
Human, Dog, Pig, Horse, Rabbit, Guinea pig, Mouse, Rat
Application
WB
$289.00
  pAb ARP42955_P050 Rfwd2 antibody - middle region (ARP42955_P050)
Reacts with
Bovine, Dog, Human, Pig, Horse, Rabbit, Guinea pig, Rat, Mouse
Application
WB
$289.00
  pAb ARP57979_P050 KDM2A Antibody - middle region (ARP57979_P050)
Reacts with
Pig, Bovine, Dog, Horse, Rabbit, Human, Rat, Mouse, Guinea pig
Application
WB
$289.00
  pAb ARP34759_P050 Arhgap5 antibody - N-terminal region (ARP34759_P050)
Reacts with
Human, Mouse, Rat, Bovine, Pig, Horse, Rabbit, Guinea pig, Dog, Zebrafish
Application
WB
$289.00
  pAb ARP58078_P050 SLC18A1 Antibody - N-terminal region (ARP58078_P050)
Reacts with
Human, Bovine, Pig, Dog, Horse
Application
WB
$289.00
  pAb ARP45622_P050 RORC antibody - N-terminal region (ARP45622_P050)
Reacts with
Pig, Bovine, Horse, Human, Rat, Guinea pig, Dog, Mouse, Rabbit
Application
WB, IHC
$289.00
  pAb ARP38138_P050 Aff3 antibody - C-terminal region (ARP38138_P050)
Reacts with
Mouse, Rat, Dog, Pig, Horse, Rabbit, Human, Bovine, Zebrafish
Application
WB
$289.00
  pAb ARP31582_P050 ZNF586 Antibody - middle region (ARP31582_P050)
Reacts with
Human, Dog, Horse, Bovine, Pig, Rabbit, Guinea pig, Rat, Mouse
Application
WB
$289.00
  pAb ARP30901_P050 CBFB Antibody - N-terminal region (ARP30901_P050)
Reacts with
Human, Bovine, Dog, Rabbit, Rat, Pig, Mouse, Zebrafish, Yeast, Horse, Guinea pig
Application
WB
$289.00
  pAb ARP32262_P050 NR2E3 Antibody - middle region (ARP32262_P050)
Reacts with
Human, Bovine, Horse, Zebrafish, Pig, Rat, Guinea pig, Mouse
Application
WB
$289.00

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Showing 421 - 450 of 3976