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Now Offering Over 85,203 Antibodies & 34,301 Antigens!

Transcription Factor Antibodies

Transcription factors are proteins that regulate gene expression by binding to DNA via one or more DNA-binding domains. This binding is achieved via a combination of electrostatic and van der waals forces and can occur at many closely-related sequences flanking different genes. Once bound to DNA directly or as part of a complex, they can promote or inhibit RNA polymerase recruitment, thereby acting as activators or repressors, respectively. Alternatively, transcription factors can act to recruit coactivators and corepressors or to catalyze histone acetylation and deacetylation. Transcription factors can function downstream of signaling cascades triggered by biological or environmental (ex. hypoxia, hyperthermia) stimuli to alter the expression of target genes. Ligand binding is necessary to activate some transcription factors as this can cause nuclear translocation and changes in the binding affinities for DNA and cofactors. During development, various stimuli can cause transcription factors to up- or down-regulate expression of specific genes at distinct time points to ensure proper development. Transcription factors can function as oncogenes or tumor suppressors and have thus been linked to various cancers. Accordingly, some therapeutic approaches in cancer therapy involve targeting transcription factor families[1].

1. Darnell JE Jr. 2002. Transcription factors as targets for cancer therapy. Nat Rev Cancer. Oct;2(10):740-9.

Transcription Factor Antibodies Top 20 Showcase

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Transcription Factors are involved in transcriptional regulation in the form of up regulation or down regulation acting as either repressors or activators of transcription. We have manufactured more than 3000 antibody products covering almost every known human and mouse transcription factors.

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Showing 421 - 450 of 4022
  Type Catalog # Product Product Images Price (USD)
  pAb ARP32426_P050 DACH2 Antibody - C-terminal region (ARP32426_P050)
Reacts with
Human, Horse, Rabbit, Mouse, Dog, Rat, Bovine
Application
WB
$289.00
  pAb ARP50680_P050 Plekhf2 antibody - N-terminal region (ARP50680_P050)
Reacts with
Mouse, Rat, Rabbit, Human, Bovine, Horse, Guinea pig
Application
WB
$289.00
  pAb ARP38163_P050 Nfic Antibody - N-terminal region (ARP38163_P050)
Reacts with
Mouse, Bovine, Human, Zebrafish, Dog, Pig, Rat, Horse, Guinea pig, Sheep
Application
WB
$289.00
  pAb ARP36823_P050 Arntl Antibody - C-terminal region (ARP36823_P050)
Reacts with
Rat, Mouse, Horse, Pig, Human, Sheep, Bovine, Rabbit, Guinea pig, Dog
Application
WB
$289.00
  pAb ARP63516_P050 Reg1 antibody - middle region (ARP63516_P050)
Reacts with
Human, Rat, Mouse, Rabbit
Application
WB
$289.00
  pAb ARP37038_P050 Esr2 Antibody - N-terminal region (ARP37038_P050)
Reacts with
Dog, Mouse, Pig, Goat, Rat, Sheep, Bovine, Horse, Guinea pig, Human, Rabbit
Application
WB
$289.00
  pAb ARP63749_P050 CD226 antibody - C-terminal region (ARP63749_P050)
Reacts with
Human, Rat, Horse, Guinea pig
Application
WB
$289.00
  pAb ARP47578_P050 ZNF397 Antibody - middle region (ARP47578_P050)
Reacts with
Human, Bovine, Pig, Horse, Rabbit, Rat, Guinea pig, Dog, Mouse, Goat
Application
WB
$289.00
  pAb ARP43555_P050 Dpy19l1 antibody - C-terminal region (ARP43555_P050)
Reacts with
Mouse, Rat, Zebrafish, Bovine, Dog, Horse, Rabbit, Guinea pig, Human
Application
WB
$289.00
  pAb ARP60528_P050 Vps25 Antibody - C-terminal region (ARP60528_P050)
Reacts with
Mouse, Dog, Human, Rat, Bovine, Guinea pig
Application
WB
$289.00
  pAb ARP46669_P050 Man1a antibody - N-terminal region (ARP46669_P050)
Reacts with
Mouse, Bovine, Dog, Pig, Horse, Rabbit, Rat, Human, Zebrafish
Application
WB
$289.00
  pAb ARP34181_T100 CSRP3 antibody - middle region (ARP34181_T100)
Reacts with
Human, Pig, Dog, Horse, Rabbit, Rat, Guinea pig, Mouse, Bovine
Application
WB
$229.00
  pAb ARP31253_P050 Atf3 Antibody - C-terminal region (ARP31253_P050)
Reacts with
Dog, Pig, Horse, Rabbit, Guinea pig, Human, Rat, Bovine, Mouse, Zebrafish
Application
WB
$289.00
  pAb ARP72147_P050 SOHLH2 Antibody - N-terminal region (ARP72147_P050)
Reacts with
Human, Dog, Rat, Guinea pig
Application
WB
$289.00
  pAb ARP53268_P050 C11orf42 antibody - C-terminal region (ARP53268_P050)
Reacts with
Human, Rat, Bovine, Horse, Guinea pig, Mouse, Dog, Rabbit
Application
WB
$289.00
  pAb ARP31119_P050 PGR Antibody - N-terminal region (ARP31119_P050)
Reacts with
Human, Mouse, Rat, Pig, Yeast, Rabbit, Goat
Application
WB
$289.00
  pAb ARP62184_P050 NSL1 antibody - C-terminal region (ARP62184_P050)
Reacts with
Human, Bovine
Application
WB
$289.00
  pAb ARP39402_P050 PRDM7 Antibody - N-terminal region (ARP39402_P050)
Reacts with
Horse, Rabbit, Pig, Human, Bovine, Rat, Mouse
Application
WB
$289.00
  pAb ARP37587_P050 Radil Antibody - C-terminal region (ARP37587_P050)
Reacts with
Mouse, Rat, Guinea pig
Application
WB
$289.00
  pAb ARP60696_P050 HSH2D antibody - C-terminal region (ARP60696_P050)
Reacts with
Human
Application
WB
$289.00
  pAb ARP53574_P050 AURKA Antibody - middle region (ARP53574_P050)
Reacts with
Human, Bovine, Dog, Horse, Mouse, Rabbit, Rat, Guinea pig, Zebrafish, Sheep
Application
WB
$289.00
  pAb ARP35035_P050 Accn2 antibody - N-terminal region (ARP35035_P050)
Reacts with
Human, Horse, Rabbit, Guinea pig, Dog, Rat, Mouse, Bovine
Application
WB
$289.00
  pAb ARP50985_P050 ZNF679 Antibody - N-terminal region (ARP50985_P050)
Reacts with
Human
Application
WB
$289.00
  pAb ARP34068_P050 Ppara antibody - C-terminal region (ARP34068_P050)
Reacts with
Human, Horse, Pig, Rabbit, Goat, Mouse, Rat, Bovine, Dog, Zebrafish, Guinea pig, Sheep
Application
WB
$289.00
  pAb ARP39560_P050 Prrx1 Antibody - C-terminal region (ARP39560_P050)
Reacts with
Bovine, Dog, Rabbit, Rat, Guinea pig, Human, Mouse, Zebrafish
Application
WB
$289.00
  pAb ARP43174_P050 Ubox5 antibody - middle region (ARP43174_P050)
Reacts with
Dog, Bovine, Pig, Horse, Rabbit, Human, Rat, Guinea pig, Mouse
Application
WB
$289.00
  pAb ARP33008_P050 Prrx2 Antibody - middle region (ARP33008_P050)
Reacts with
Dog, Human, Rat, Bovine, Pig, Horse, Rabbit, Guinea pig, Mouse
Application
WB
$289.00
  pAb ARP52904_P050 Paqr4 antibody - C-terminal region (ARP52904_P050)
Reacts with
Bovine, Human, Dog, Rat, Guinea pig, Mouse, Goat, Rabbit
Application
WB
$289.00
  pAb ARP38312_P050 ZFX Antibody - C-terminal region (ARP38312_P050)
Reacts with
Zebrafish, Mouse, Human, Rat, Dog, Bovine, Pig, Horse, Rabbit, Guinea pig
Application
WB
$289.00
  pAb ARP38020_P050 Ldb2 antibody - N-terminal region (ARP38020_P050)
Reacts with
Rat, Human, Dog, Bovine, Horse, Rabbit, Guinea pig, Mouse, Zebrafish
Application
WB
$289.00

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Showing 421 - 450 of 4022