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Now Offering Over 85,203 Antibodies & 34,301 Antigens!

Transcription Factor Antibodies

Transcription factors are proteins that regulate gene expression by binding to DNA via one or more DNA-binding domains. This binding is achieved via a combination of electrostatic and van der waals forces and can occur at many closely-related sequences flanking different genes. Once bound to DNA directly or as part of a complex, they can promote or inhibit RNA polymerase recruitment, thereby acting as activators or repressors, respectively. Alternatively, transcription factors can act to recruit coactivators and corepressors or to catalyze histone acetylation and deacetylation. Transcription factors can function downstream of signaling cascades triggered by biological or environmental (ex. hypoxia, hyperthermia) stimuli to alter the expression of target genes. Ligand binding is necessary to activate some transcription factors as this can cause nuclear translocation and changes in the binding affinities for DNA and cofactors. During development, various stimuli can cause transcription factors to up- or down-regulate expression of specific genes at distinct time points to ensure proper development. Transcription factors can function as oncogenes or tumor suppressors and have thus been linked to various cancers. Accordingly, some therapeutic approaches in cancer therapy involve targeting transcription factor families[1].

1. Darnell JE Jr. 2002. Transcription factors as targets for cancer therapy. Nat Rev Cancer. Oct;2(10):740-9.

Transcription Factor Antibodies Top 20 Showcase

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Transcription Factors are involved in transcriptional regulation in the form of up regulation or down regulation acting as either repressors or activators of transcription. We have manufactured more than 3000 antibody products covering almost every known human and mouse transcription factors.

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Showing 421 - 450 of 4153
  Type Catalog # Product Product Images Price (USD)
  pAb ARP34597_P050 PRDM11 Antibody - C-terminal region (ARP34597_P050)
Reacts with
Human, Bovine, Dog, Pig, Mouse, Horse, Rabbit, Rat
Application
WB
$289.00
  pAb ARP32033_P050 NAB2 Antibody - N-terminal region (ARP32033_P050)
Reacts with
Dog, Pig, Horse, Rabbit, Human, Bovine
Application
WB
$289.00
  pAb ARP51638_P050 MYCNOS antibody - N-terminal region (ARP51638_P050)
Reacts with
Human
Application
WB
$289.00
  pAb ARP34748_P050 BANP Antibody - N-terminal region (ARP34748_P050)
Reacts with
Human, Horse, Bovine, Rat, Guinea pig, Rabbit, Mouse, Yeast, Dog
Application
WB
$289.00
  pAb ARP37264_P050 Rybp Antibody - N-terminal region (ARP37264_P050)
Reacts with
Rat, Rabbit, Mouse, Bovine, Dog, Pig, Horse, Guinea pig, Human, Zebrafish, Yeast
Application
WB
$289.00
  pAb ARP63639_P050 CDC73 antibody - C-terminal region (ARP63639_P050)
Reacts with
Dog, Bovine, Rat, Horse, Rabbit, Human, Mouse, Zebrafish
Application
WB
$289.00
  pAb ARP34591_P050 METTL3 antibody - C-terminal region (ARP34591_P050)
Reacts with
Bovine, Human, Dog, Pig, Horse, Goat, Rabbit, Mouse, Rat, Guinea pig, Zebrafish
Application
WB
$289.00
  pAb ARP39301_P050 ZNF280D Antibody - N-terminal region (ARP39301_P050)
Reacts with
Human, Dog, Horse, Rabbit, Guinea pig, Rat, Mouse, Bovine
Application
IHC, WB
$289.00
  pAb ARP64882_P050 LTV1 antibody - C-terminal region (ARP64882_P050)
Reacts with
Horse, Human, Dog, Rabbit, Rat, Bovine, Guinea pig, Mouse
Application
WB
$289.00
  pAb ARP62050_P050 ACOT8 antibody - N-terminal region (ARP62050_P050)
Reacts with
Human
Application
WB
$289.00
  pAb ARP50617_P050 MBTD1 Antibody - N-terminal region (ARP50617_P050)
Reacts with
Mouse, Dog, Bovine, Pig, Horse, Rabbit, Rat, Guinea pig, Human, Zebrafish, Yeast
Application
WB
$289.00
  pAb ARP34244_P050 CDC25A Antibody - N-terminal region (ARP34244_P050)
Reacts with
Bovine, Human, Dog, Horse, Rabbit, Rat, Guinea pig, Mouse
Application
WB
$289.00
  pAb ARP49151_P050 NAT8L antibody - C-terminal region (ARP49151_P050)
Reacts with
Rat, Bovine, Dog, Pig, Horse, Rabbit, Guinea pig, Mouse, Human, Zebrafish
Application
WB
$289.00
  pAb ARP66128_P050 AKNA Antibody - C-terminal region (ARP66128_P050)
Reacts with
Human, Rabbit, Rat
Application
WB
$289.00
  pAb ARP30932_P050 LYL1 Antibody - C-terminal region (ARP30932_P050)
Reacts with
Pig, Human
Application
WB
$289.00
  pAb ARP54551_P050 LAMA4 antibody - C-terminal region (ARP54551_P050)
Reacts with
Human
Application
WB
$289.00
  pAb ARP71985_P050 WDR31 Antibody - middle region (ARP71985_P050)
Reacts with
Human, Guinea pig, Rat, Bovine, Mouse
Application
WB
$289.00
  pAb ARP33371_P050 BRD3 Antibody - middle region (ARP33371_P050)
Reacts with
Human
Application
WB
$289.00
  pAb ARP56510_P050 Rangap1 antibody - N-terminal region (ARP56510_P050)
Reacts with
Bovine, Rat, Dog, Horse, Rabbit, Guinea pig, Human, Mouse, Zebrafish
Application
WB
$289.00
  pAb ARP38237_P050 SP8 Antibody - middle region (ARP38237_P050)
Reacts with
Zebrafish, Rat, Mouse, Dog, Horse, Rabbit, Guinea pig, Human, Bovine
Application
WB
$289.00
  pAb ARP59927_P050 MRGPRX4 antibody - C-terminal region (ARP59927_P050)
Reacts with
Human, Rabbit, Mouse
Application
WB
$289.00
  pAb ARP42516_P050 Lrp2bp antibody - middle region (ARP42516_P050)
Reacts with
Human, Bovine, Dog, Pig, Horse, Rabbit, Rat, Mouse, Guinea pig, Zebrafish
Application
WB
$289.00
  pAb ARP41046_P050 BRD9 Antibody - N-terminal region (ARP41046_P050)
Reacts with
Horse, Rabbit, Human, Dog, Rat, Bovine, Guinea pig, Mouse, Yeast, Zebrafish
Application
WB
$289.00
  pAb ARP35254_P050 Kctd3 antibody - middle region (ARP35254_P050)
Reacts with
Human, Rat, Dog, Zebrafish, Pig, Horse, Rabbit, Guinea pig, Bovine, Mouse
Application
WB
$289.00
  pAb ARP35182_P050 ABCC4 antibody - C-terminal region (ARP35182_P050)
Reacts with
Rabbit, Human, Mouse, Dog, Rat, Bovine, Horse, Guinea pig, Yeast
Application
WB
$289.00
  pAb ARP40188_P050 Gapdh Antibody - C-terminal region (ARP40188_P050)
Reacts with
Bovine, Rat, Horse, Rabbit, Guinea pig, Human, Dog, Mouse
Application
WB
$289.00
  pAb ARP43824_P050 Slc31a1 antibody - N-terminal region (ARP43824_P050)
Reacts with
Mouse, Horse, Rat, Human, Dog, Rabbit
Application
WB
$289.00
  pAb ARP70576_P050 INO80C Antibody - N-terminal region (ARP70576_P050)
Reacts with
Human, Mouse, Rabbit, Rat, Bovine, Dog, Pig, Horse, Guinea pig
Application
WB
$289.00
  pAb ARP30574_P050 ID3 Antibody - N-terminal region (ARP30574_P050)
Reacts with
Pig, Horse, Rabbit, Human, Dog, Sheep, Rat, Bovine, Mouse, Guinea pig
Application
WB
$289.00
  pAb ARP37358_P050 Ilf2 Antibody - N-terminal region (ARP37358_P050)
Reacts with
Rat, Human, Dog, Bovine, Horse, Rabbit, Guinea pig, Mouse, Zebrafish
Application
WB
$289.00

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Showing 421 - 450 of 4153