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Now Offering Over 48,216 Antibodies & 21,887 Antigens!

Transcription Factor Antibodies

Transcription factors are proteins that regulate gene expression by binding to DNA via one or more DNA-binding domains. This binding is achieved via a combination of electrostatic and van der waals forces and can occur at many closely-related sequences flanking different genes. Once bound to DNA directly or as part of a complex, they can promote or inhibit RNA polymerase recruitment, thereby acting as activators or repressors, respectively. Alternatively, transcription factors can act to recruit coactivators and corepressors or to catalyze histone acetylation and deacetylation. Transcription factors can function downstream of signaling cascades triggered by biological or environmental (ex. hypoxia, hyperthermia) stimuli to alter the expression of target genes. Ligand binding is necessary to activate some transcription factors as this can cause nuclear translocation and changes in the binding affinities for DNA and cofactors. During development, various stimuli can cause transcription factors to up- or down-regulate expression of specific genes at distinct time points to ensure proper development. Transcription factors can function as oncogenes or tumor suppressors and have thus been linked to various cancers. Accordingly, some therapeutic approaches in cancer therapy involve targeting transcription factor families[1].

1. Darnell JE Jr. 2002. Transcription factors as targets for cancer therapy. Nat Rev Cancer. Oct;2(10):740-9.

Transcription Factor Antibodies Top 20 Showcase

View the entire product list by clicking here.

Transcription Factors are involved in transcriptional regulation in the form of up regulation or down regulation acting as either repressors or activators of transcription. We have manufactured more than 3000 antibody products covering almost every known human and mouse transcription factors.

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Showing 271 - 300 of 3657
  Type Catalog # Product Product Images Price (USD)
  pAb ARP31830_T100 ZFP95 antibody - N-terminal region (ARP31830_T100)
Reacts with
Western Gorilla, Pygmy chimpanzee, Pig-tailed macaque, Chimpanzee, Human, Common woolly monkey, Mouse
Application
WB
$229.00
  pAb ARP31834_P050 NR5A1 antibody - middle region (ARP31834_P050)
Reacts with
Human, Dog, Guinea pig, Pig, Rabbit
Application
WB, IHC
$289.00
  pAb ARP31836_T100 ZNF620 antibody - middle region (ARP31836_T100)
Reacts with
Bovine, Sumatran orangutan, Human
Application
WB
$229.00
  pAb ARP31839_T100 PTF1A antibody - N-terminal region (ARP31839_T100)
Reacts with
Human, African clawed frog, Bovine, Mouse, Rat, Zebrafish, Dog, Horse
Application
WB
$229.00
  pAb ARP31841_T100 SPDEF antibody - N-terminal region (ARP31841_T100)
Reacts with
Human, Mouse, Pig, Rabbit, Rat, Dog, Bovine
Application
WB
$229.00
  pAb ARP31848_T100 C20ORF194 antibody - C-terminal region (ARP31848_T100)
Reacts with
Human, Bovine, Chicken, Dog, Horse
Application
WB
$229.00
  pAb ARP31852_P050 ZNF500 antibody - middle region (ARP31852_P050)
Reacts with
Human
Application
WB, IHC
$289.00
  pAb ARP31853_T100 ZBTB20 antibody - middle region (ARP31853_T100)
Reacts with
Bovine, Dog, Horse, Human, Mouse, Rabbit, Rat, Guinea pig
Application
WB
$229.00
  pAb ARP31855_T100 GATA2 antibody - N-terminal region (ARP31855_T100)
Reacts with
Bovine, Dog, Guinea pig, Horse, Human, Mouse, Pig, Rat, African clawed frog, Chicken
Application
WB, IHC
$229.00
  pAb ARP31856_P050 NKX2-8 antibody - C-terminal region (ARP31856_P050)
Reacts with
Rabbit, Rat, Bovine
Application
WB
$289.00
  pAb ARP31857_P050 GATA3 antibody - N-terminal region (ARP31857_P050)
Reacts with
Bovine, Chicken, Dog, Horse, Human, Mouse, Pig, Rabbit, Rat, Sheep, Guinea pig, Zebrafish
Application
WB, IHC
$289.00
  pAb ARP31859_P050 GATA6 antibody - middle region (ARP31859_P050)
Reacts with
Horse, Human, Pig, Rabbit, Sheep, Bovine, Rat, Guinea pig, Chicken, Mouse
Application
WB, IF, IHC
$289.00
  pAb ARP31860_P050 MYCBP antibody - middle region (ARP31860_P050)
Reacts with
Guinea pig, Human, Bovine, Chicken, Dog, Mouse, Pig
Application
WB, IHC
$289.00
  pAb ARP31860_T100 MYCBP antibody - middle region (ARP31860_T100)
Reacts with
Guinea pig, Human, Bovine, Chicken, Dog, Mouse, Pig
Application
WB, IHC
$229.00
  pAb ARP31861_T100 EHF antibody - N-terminal region (ARP31861_T100)
Reacts with
Bovine, Chicken, Dog, Human, Rabbit, Mouse, Rat
Application
WB, IHC
$229.00
  pAb ARP31862_T100 GBX2 antibody - middle region (ARP31862_T100)
Reacts with
Bovine, Dog, Human, Rabbit, Guinea pig, Pig, Mouse, Rat
Application
WB
$229.00
  pAb ARP31866_T100 HEYL antibody - N-terminal region (ARP31866_T100)
Reacts with
Human, Mouse, Rat, Bovine, Dog, Pig
Application
WB
$229.00
  pAb ARP31867_P050 AATF antibody - N-terminal region (ARP31867_P050)
Reacts with
Human, Rabbit, Horse, Dog
Application
WB, IHC
$289.00
  pAb ARP31869_P050 GFI1 antibody - N-terminal region (ARP31869_P050)
Reacts with
Bovine, Dog, Guinea pig, Horse, Human, Mouse, Pig, Rabbit, Rat
Application
WB
$289.00
  pAb ARP31877_P050 TAF5L antibody - N-terminal region (ARP31877_P050)
Reacts with
Dog, Horse, Human, Rabbit, Bovine, Pig, Mouse, Rat, Chicken
Application
WB
$289.00
  pAb ARP31879_P050 Aff4 Antibody - middle region (ARP31879_P050)
Reacts with
Application
WB
$289.00
  pAb ARP31884_P050 HTATSF1 antibody - C-terminal region (ARP31884_P050)
Reacts with
Human, Mouse, Rabbit, Rat, Bovine, Guinea pig, Dog
Application
WB
$289.00
  pAb ARP31885_T100 GLI2 antibody - N-terminal region (ARP31885_T100)
Reacts with
Human
Application
WB, IHC
$229.00
  pAb ARP31887_P050 MKX antibody - middle region (ARP31887_P050)
Reacts with
African clawed frog, Bovine, Chicken, Dog, Human, Rabbit, Mouse, Rat
Application
WB
$289.00
  pAb ARP31890_T100 ZNF620 antibody - C-terminal region (ARP31890_T100)
Reacts with
Human, Bovine, Pig, Mouse, Rat, Pygmy chimpanzee, Sumatran orangutan, Western Gorilla, Bornean orangutan, White-tufted-ear marmoset, Dog, eastern European house mouse, Southeastern Asian house mouse, Steppe mouse, Macedonian mouse, Japanese house mouse, w
Application
WB
$229.00
  pAb ARP31893_P050 ZNF545 antibody - C-terminal region (ARP31893_P050)
Reacts with
Rat, Mouse, Crab-eating macaque, Human, Bovine
Application
WB
$289.00
  pAb ARP31896_P050 ZNF775 antibody - N-terminal region (ARP31896_P050)
Reacts with
Human
Application
WB
$289.00
  pAb ARP31900_P050 KLF15 antibody - middle region (ARP31900_P050)
Reacts with
Human, Rabbit, Guinea pig, Mouse, Rat, Pig
Application
WB
$289.00
  pAb ARP31902_P050 FHL1 antibody - N-terminal region (ARP31902_P050)
Reacts with
Bovine, Dog, Guinea pig, Mouse, Pig, Rabbit, Rat, Sheep, Horse, African clawed frog, Human
Application
WB
$289.00
  pAb ARP31905_T100 RACGAP1 antibody - N-terminal region (ARP31905_T100)
Reacts with
Bovine, Dog, Horse, Human, Rabbit, African clawed frog, Mouse, Rat
Application
WB
$229.00

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Showing 271 - 300 of 3657