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Now Offering Over 48,216 Antibodies & 21,887 Antigens!

Transcription Factor Antibodies

Transcription factors are proteins that regulate gene expression by binding to DNA via one or more DNA-binding domains. This binding is achieved via a combination of electrostatic and van der waals forces and can occur at many closely-related sequences flanking different genes. Once bound to DNA directly or as part of a complex, they can promote or inhibit RNA polymerase recruitment, thereby acting as activators or repressors, respectively. Alternatively, transcription factors can act to recruit coactivators and corepressors or to catalyze histone acetylation and deacetylation. Transcription factors can function downstream of signaling cascades triggered by biological or environmental (ex. hypoxia, hyperthermia) stimuli to alter the expression of target genes. Ligand binding is necessary to activate some transcription factors as this can cause nuclear translocation and changes in the binding affinities for DNA and cofactors. During development, various stimuli can cause transcription factors to up- or down-regulate expression of specific genes at distinct time points to ensure proper development. Transcription factors can function as oncogenes or tumor suppressors and have thus been linked to various cancers. Accordingly, some therapeutic approaches in cancer therapy involve targeting transcription factor families[1].

1. Darnell JE Jr. 2002. Transcription factors as targets for cancer therapy. Nat Rev Cancer. Oct;2(10):740-9.

Transcription Factor Antibodies Top 20 Showcase

View the entire product list by clicking here.

ARP46323_CENP-M CENPM Antibody
ARP57258_CENP-N CENPN Antibody
ARP30312_TP53 TP53 Antibody
ARP38253_P050-STAT3-IHC-01 STAT3 Antibody
ARP37894_P050_TGF-beta-1 TGFB1 Antibody
ARP30947_PAX7_IF_image_01 PAX7 Antibody
ARP41404_CYP1A1_IHC_image_01 CYP1A1 Antibody
ARP33326_SOX10 SOX10 Antibody
ARP45222_P050_HMOX1_WB_imag HMOX1 Antibody
ARP32548-p50-GATA3-IF-img-0 GATA3 Antibody
ARP32372-HES1-WB-01 HES1 Antibody
ARP37018-ATF4-IF-image-01 ATF4 Antibody
ARP48127_CD36 CD36 Antibody
ARP31400-TFAM-WB-04 TFAM Antibody
ARP32752_OLIG2 Nterm OLIG2 N term Antibody
ARP31859-p50-GATA6-IF-img-02 GATA6 Antibody
ARP33090_T100_MMP9 MMP9 Antibody
AVARP20016_T100_MMP-2 MMP2 Antibody
AVARP20010_KDR KDR Antibody
ARP41456-MUC1-IHC-image-01 MUC1 Antibody

Polyclonal Antibody - Transcription Factors

Transcription Factors are involved in transcriptional regulation in the form of up regulation or down regulation acting as either repressors or activators of transcription. We have manufactured more than 3000 antibody products covering almost every known human and mouse transcription factors.

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Showing 1 - 30 of 206
  Type Catalog # Product Product Images Price (USD)
  pAb ARP30103_T100 RBM10 antibody - N-terminal region (ARP30103_T100)
Reacts with
Bovine, Dog, Guinea pig, Horse, Human, Mouse, Pig, Rabbit, Rat
Application
WB, IHC
 $229.00
  pAb ARP30104_T100 RBM10 antibody - N-terminal region (ARP30104_T100)
Reacts with
Bovine, Guinea pig, Horse, Human, Mouse, Pig, Rabbit, Dog
Application
WB, IHC
 $229.00
  pAb ARP30305_P050 RELA antibody - middle region (ARP30305_P050)
Reacts with
Bovine, Mouse, Pig, Rat
Application
WB
 $289.00
  pAb ARP30371_P050 RELA antibody - middle region (ARP30371_P050)
Reacts with
Application
WB
 $289.00
  pAb ARP30954_P050 RUNX1 antibody - middle region (ARP30954_P050)
Reacts with
African clawed frog, Chicken, Human, Bovine, Dog, Horse, Pig, Rabbit, Mouse, Rat
Application
WB, IHC
 $289.00
  pAb ARP31064_P050 Runx2 antibody - C-terminal region (ARP31064_P050)
Reacts with
African clawed frog, Bovine, Chicken, Dog, Guinea pig, Horse, Human, Mouse, Pig, Rat, Zebrafish
Application
WB
 $289.00
  pAb ARP31121_P050 RBPSUH antibody - C-terminal region (ARP31121_P050)
Reacts with
Mouse
Application
WB, IHC
 $289.00
  pAb ARP31513_T100 RIPK3 antibody - N-terminal region (ARP31513_T100)
Reacts with
Human, Dog, Horse, Mouse, Pig, Bovine
Application
WB, IHC
 $229.00
  pAb ARP31819_P050 RYBP antibody - middle region (ARP31819_P050)
Reacts with
Bovine, Dog, Guinea pig, Horse, Human, Pig, Rabbit, Mouse, Rat, Chicken
Application
WB, IHC
 $289.00
  pAb ARP31905_T100 RACGAP1 antibody - N-terminal region (ARP31905_T100)
Reacts with
Bovine, Dog, Horse, Human, Rabbit, African clawed frog, Mouse, Rat
Application
WB
 $229.00
  pAb ARP31916_P050 REPIN1 antibody - middle region (ARP31916_P050)
Reacts with
Human, Mouse, Rabbit
Application
WB
 $289.00
  pAb ARP31926_P050 RAX antibody - N-terminal region (ARP31926_P050)
Reacts with
Bovine, Guinea pig, Horse, Human, Mouse, Pig, Rat, Rabbit, Dog
Application
WB, IHC
 $289.00
  pAb ARP32145_P050 Rnf166 antibody - middle region (ARP32145_P050)
Reacts with
Horse, Mouse, Bovine, Dog, Chicken
Application
WB
 $289.00
  pAb ARP32150_P050 RNF12 antibody - N-terminal region (ARP32150_P050)
Reacts with
Human, Mouse
Application
WB
 $289.00
  pAb ARP32151_P050 RNF12 antibody - C-terminal region (ARP32151_P050)
Reacts with
African clawed frog, Chicken, Human, Mouse
Application
WB, IHC
 $289.00
  pAb ARP32164_P050 RAX antibody - N-terminal region (ARP32164_P050)
Reacts with
Dog, Guinea pig, Rat
Application
WB
 $289.00
  pAb ARP32378_T100 RUVBL2 antibody - N-terminal region (ARP32378_T100)
Reacts with
Dog, Guinea pig, Horse, Mouse, Pig, Rabbit, Rat, African clawed frog, Zebrafish
Application
WB, IHC
 $229.00
  pAb ARP32379_P050 RUVBL2 antibody - N-terminal region (ARP32379_P050)
Reacts with
Dog, Guinea pig, Horse, Human, Mouse, Pig, Rabbit, Rat, African clawed frog, Zebrafish
Application
WB, IHC
 $289.00
  pAb ARP32478_P050 REST antibody - middle region (ARP32478_P050)
Reacts with
Human, Bovine, Chicken, Dog, Guinea pig, Horse, Mouse, Pig, Rabbit, Rat, African clawed frog
Application
WB
 $289.00
  pAb ARP32490_P050 RBL1 antibody - middle region (ARP32490_P050)
Reacts with
Bovine, Dog, Horse, Human, Mouse, Rat, Chicken, Rabbit
Application
WB
 $289.00
  pAb ARP32595_P050 RACGAP1 antibody - N-terminal region (ARP32595_P050)
Reacts with
Bovine, Human, Dog, Rabbit, Mouse
Application
WB
 $289.00
  pAb ARP32713_P050 RERE antibody - N-terminal region (ARP32713_P050)
Reacts with
African clawed frog, Bovine, Human, Mouse, Rabbit, Rat, Horse, Zebrafish
Application
WB
 $289.00
  pAb ARP32835_P050 RIPK3 antibody - N-terminal region (ARP32835_P050)
Reacts with
Human, Bovine, Pig, Rat, Horse, Mouse
Application
WB
 $289.00
  pAb ARP32914_T100 RNF130 antibody - N-terminal region (ARP32914_T100)
Reacts with
Bovine, Human, Mouse, Rabbit
Application
WB
 $229.00
  pAb ARP32933_P050 REXO4 antibody - C-terminal region (ARP32933_P050)
Reacts with
Dog, Human, Mouse, Rat, Horse, African clawed frog, Guinea pig, Bovine
Application
WB
 $289.00
  pAb ARP32934_P050 REXO4 antibody - middle region (ARP32934_P050)
Reacts with
Human
Application
WB
 $289.00
  pAb ARP32971_P050 RBAK antibody - N-terminal region (ARP32971_P050)
Reacts with
Human, Bovine, Rat, Guinea pig, Horse, Mouse, Pig, Dog
Application
WB
 $289.00
  pAb ARP32972_P050 RBAK antibody - middle region (ARP32972_P050)
Reacts with
Bovine, Guinea pig, Horse, Human, Pig, Mouse, Rat, Rabbit
Application
WB, IHC
 $289.00
  pAb ARP32972_T100 RBAK antibody - middle region (ARP32972_T100)
Reacts with
Bovine, Guinea pig, Horse, Human, Pig, Mouse, Rat, Rabbit
Application
WB
 $229.00
  pAb ARP33005_P050 RNF138 antibody - C-terminal region (ARP33005_P050)
Reacts with
Dog, Guinea pig, Horse, Rat, Chicken
Application
WB
 $289.00

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Showing 1 - 30 of 206

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