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Now Offering Over 85,203 Antibodies & 34,301 Antigens!

Transcription Factor Antibodies

Transcription factors are proteins that regulate gene expression by binding to DNA via one or more DNA-binding domains. This binding is achieved via a combination of electrostatic and van der waals forces and can occur at many closely-related sequences flanking different genes. Once bound to DNA directly or as part of a complex, they can promote or inhibit RNA polymerase recruitment, thereby acting as activators or repressors, respectively. Alternatively, transcription factors can act to recruit coactivators and corepressors or to catalyze histone acetylation and deacetylation. Transcription factors can function downstream of signaling cascades triggered by biological or environmental (ex. hypoxia, hyperthermia) stimuli to alter the expression of target genes. Ligand binding is necessary to activate some transcription factors as this can cause nuclear translocation and changes in the binding affinities for DNA and cofactors. During development, various stimuli can cause transcription factors to up- or down-regulate expression of specific genes at distinct time points to ensure proper development. Transcription factors can function as oncogenes or tumor suppressors and have thus been linked to various cancers. Accordingly, some therapeutic approaches in cancer therapy involve targeting transcription factor families[1].

1. Darnell JE Jr. 2002. Transcription factors as targets for cancer therapy. Nat Rev Cancer. Oct;2(10):740-9.

Transcription Factor Antibodies Top 20 Showcase

View the entire product list by clicking here.

Transcription Factors are involved in transcriptional regulation in the form of up regulation or down regulation acting as either repressors or activators of transcription. We have manufactured more than 3000 antibody products covering almost every known human and mouse transcription factors.

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Showing 1 - 30 of 280
  Type Catalog # Product Product Images Price (USD)
  pAb ARP30947_P050 Pax7 antibody - middle region (ARP30947_P050)
Reacts with
Zebrafish, Rat, Bovine, Dog, Human, Rabbit, Mouse, Guinea pig, Goat
Application
IF, WB
$289.00
  pAb ARP30948_P050 PBX1 antibody - N-terminal region (ARP30948_P050)
Reacts with
Human, Rat, Mouse, Bovine, Dog, Pig
Application
WB
$289.00
  pAb ARP31119_P050 PGR Antibody - N-terminal region (ARP31119_P050)
Reacts with
Human, Mouse, Rat, Pig, Yeast, Rabbit, Goat
Application
WB
$289.00
  pAb ARP31218_P050 POU3F2 antibody - middle region (ARP31218_P050)
Reacts with
Rat, Guinea pig, Dog, Human, Mouse, Bovine
Application
IHC, WB
$289.00
  pAb ARP31220_P050 PAX2 Antibody - middle region (ARP31220_P050)
Reacts with
Sheep, Bovine, Dog, Pig, Horse, Zebrafish, Rabbit, Human, Rat, Guinea pig, Mouse
Application
WB
$289.00
  pAb ARP31221_P050 Pax2 antibody - middle region (ARP31221_P050)
Reacts with
Rat, Sheep, Bovine, Dog, Pig, Horse, Rabbit, Mouse, Human, Guinea pig, Zebrafish
Application
WB
$289.00
  pAb ARP31418_T100 POU1F1 antibody - N-terminal region (ARP31418_T100)
Reacts with
Goat, Pig, Bovine, Horse, Rabbit, Human, Sheep, Dog, Mouse, Rat, Guinea pig
Application
WB
$229.00
  pAb ARP31419_P050 POU1F1 antibody - C-terminal region (ARP31419_P050)
Reacts with
Bovine, Goat, Pig, Dog, Mouse, Rat, Horse, Rabbit, Guinea pig, Human, Sheep, Zebrafish
Application
IHC, WB
$289.00
  pAb ARP31433_P050 POU6F1 antibody - middle region (ARP31433_P050)
Reacts with
Human, Bovine, Dog, Horse, Rabbit, Rat, Mouse, Zebrafish
Application
IHC, WB
$289.00
  pAb ARP31454_T100 PQBP1 antibody - middle region (ARP31454_T100)
Reacts with
Human, Dog, Horse, Pig, Bovine, Rat, Mouse, Rabbit, Guinea pig
Application
IHC, WB
$229.00
  pAb ARP31507_P050 PPARGC1A antibody - N-terminal region (ARP31507_P050)
Reacts with
Human, Dog, Rat, Guinea pig, Goat, Bovine, Mouse, Horse, Rabbit, Zebrafish
Application
IF, WB
$289.00
  pAb ARP31516_P050 Prdm4 Antibody - C-terminal region (ARP31516_P050)
Reacts with
Rabbit, Rat, Human, Dog, Horse, Yeast, Bovine, Pig, Mouse
Application
WB
$289.00
  pAb ARP31527_T100 PMF1 antibody - middle region (ARP31527_T100)
Reacts with
Human, Goat, Rat, Mouse, Pig, Horse, Guinea pig, Bovine, Rabbit, Dog
Application
WB
$229.00
  pAb ARP31534_P050 POU6F2 antibody - N-terminal region (ARP31534_P050)
Reacts with
Rat, Bovine, Mouse, Human, Dog, Rabbit, Guinea pig
Application
WB
$289.00
  pAb ARP31558_P050 POU5F2 antibody - N-terminal region (ARP31558_P050)
Reacts with
Human, Rat, Mouse
Application
WB
$289.00
  pAb ARP31726_P050 PHOX2A antibody - N-terminal region (ARP31726_P050)
Reacts with
Human, Dog, Bovine, Pig, Horse, Rabbit, Rat, Guinea pig, Mouse, Zebrafish
Application
IHC, WB
$289.00
  pAb ARP31778_P050 PDK2 antibody - middle region (ARP31778_P050)
Reacts with
Human, Rat, Dog, Horse, Rabbit, Guinea pig, Mouse, Zebrafish, Bovine
Application
IHC, WB
$289.00
  pAb ARP31839_T100 PTF1A antibody - N-terminal region (ARP31839_T100)
Reacts with
Human, Bovine, Pig, Rat, Mouse, Zebrafish, Dog, Horse
Application
WB
$229.00
  pAb ARP32062_P050 PAWR antibody - middle region (ARP32062_P050)
Reacts with
Rat, Guinea pig, Human, Horse, Mouse, Rabbit
Application
IHC, WB
$289.00
  pAb ARP32064_P050 PAX4 antibody - middle region (ARP32064_P050)
Reacts with
Human, Mouse, Rabbit, Dog, Bovine, Pig, Horse, Guinea pig, Rat
Application
WB
$289.00
  pAb ARP32068_P050 PAX7 antibody - middle region (ARP32068_P050)
Reacts with
Rat, Bovine, Dog, Horse, Rabbit, Mouse, Guinea pig, Human, Zebrafish
Application
WB
$289.00
  pAb ARP32069_P050 PBX2 antibody - N-terminal region (ARP32069_P050)
Reacts with
Pig, Horse, Guinea pig, Mouse, Human, Rat
Application
WB
$289.00
  pAb ARP32070_T100 PBX3 antibody - N-terminal region (ARP32070_T100)
Reacts with
Human, Rat, Mouse, Guinea pig, Bovine, Zebrafish
Application
IHC, WB
$229.00
  pAb ARP32081_P050 PHOX2A antibody - N-terminal region (ARP32081_P050)
Reacts with
Dog, Bovine, Pig, Horse, Rabbit, Rat, Guinea pig, Human, Mouse
Application
WB
$289.00
  pAb ARP32280_P050 PQBP1 antibody - middle region (ARP32280_P050)
Reacts with
Human, Dog, Horse, Pig, Rat, Guinea pig, Bovine, Rabbit
Application
WB
$289.00
  pAb ARP32318_P050 POU1F1 antibody - middle region (ARP32318_P050)
Reacts with
Bovine, Goat, Pig, Dog, Horse, Rabbit, Guinea pig, Human, Sheep, Rat, Mouse
Application
WB
$289.00
  pAb ARP32339_P050 PITX1 antibody - N-terminal region (ARP32339_P050)
Reacts with
Human, Dog, Bovine, Pig, Mouse, Rat, Guinea pig
Application
WB
$289.00
  pAb ARP32340_P050 PITX1 antibody - middle region (ARP32340_P050)
Reacts with
Dog, Horse, Pig, Rat, Guinea pig, Mouse, Human, Bovine
Application
WB
$289.00
  pAb ARP32341_P050 PSMD4 antibody - C-terminal region (ARP32341_P050)
Reacts with
Sheep, Horse, Rabbit, Human, Rat, Bovine, Pig, Dog, Mouse, Guinea pig
Application
WB
$289.00
  pAb ARP32342_T100 PSMD4 antibody - N-terminal region (ARP32342_T100)
Reacts with
Sheep, Human, Horse, Rabbit, Dog, Mouse, Rat, Guinea pig, Bovine, Zebrafish, Yeast
Application
WB
$229.00

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Showing 1 - 30 of 280