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Transcription Factor Antibodies

Transcription factors are proteins that regulate gene expression by binding to DNA via one or more DNA-binding domains. This binding is achieved via a combination of electrostatic and van der waals forces and can occur at many closely-related sequences flanking different genes. Once bound to DNA directly or as part of a complex, they can promote or inhibit RNA polymerase recruitment, thereby acting as activators or repressors, respectively. Alternatively, transcription factors can act to recruit coactivators and corepressors or to catalyze histone acetylation and deacetylation. Transcription factors can function downstream of signaling cascades triggered by biological or environmental (ex. hypoxia, hyperthermia) stimuli to alter the expression of target genes. Ligand binding is necessary to activate some transcription factors as this can cause nuclear translocation and changes in the binding affinities for DNA and cofactors. During development, various stimuli can cause transcription factors to up- or down-regulate expression of specific genes at distinct time points to ensure proper development. Transcription factors can function as oncogenes or tumor suppressors and have thus been linked to various cancers. Accordingly, some therapeutic approaches in cancer therapy involve targeting transcription factor families[1].

1. Darnell JE Jr. 2002. Transcription factors as targets for cancer therapy. Nat Rev Cancer. Oct;2(10):740-9.

Transcription Factor Antibodies Top 20 Showcase

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Transcription Factors are involved in transcriptional regulation in the form of up regulation or down regulation acting as either repressors or activators of transcription. We have manufactured more than 3000 antibody products covering almost every known human and mouse transcription factors.

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Showing 1 - 30 of 284
  Type Catalog # Product Product Images Price (USD)
  pAb ARP72403_P050 PCNA Antibody - N-terminal region (ARP72403_P050)
Reacts with
Human
Application
WB
$289.00
  pAb ARP72562_P050 PROX1 Antibody - middle region (ARP72562_P050)
Reacts with
Human
Application
WB
$289.00
  pAb ARP38557_P050 PA24B Antibody - C-terminal region (ARP38557_P050)
Reacts with
Human
Application
WB
$289.00
  pAb ARP58059_P050 PSMD4 Antibody - C-terminal region (ARP58059_P050)
Reacts with
Human, Horse, Rabbit, Dog, Rat, Guinea pig, Sheep, Bovine, Mouse, Zebrafish
Application
WB
$289.00
  pAb ARP33217_P050 PRD12 Antibody - C-terminal region (ARP33217_P050)
Reacts with
Human
Application
WB
$289.00
  pAb ARP38063_P050 PAX6 Antibody - C-terminal region (ARP38063_P050)
Reacts with
Human
Application
WB
$289.00
  pAb ARP72430_P050 PTRF Antibody - C-terminal region (ARP72430_P050)
Reacts with
Human
Application
WB
$289.00
  pAb ARP34415_T100 PCGF3 antibody - middle region (ARP34415_T100)
Reacts with
Human, Dog, Rat, Bovine, Pig, Mouse, Rabbit, Horse, Guinea pig, Yeast
Application
WB
$229.00
  pAb ARP36965_T100 PTRF antibody - middle region (ARP36965_T100)
Reacts with
Mouse, Horse, Rat, Dog, Human, Bovine, Rabbit
Application
IHC, WB
$229.00
  pAb ARP34416_P050 PCGF3 antibody - middle region (ARP34416_P050)
Reacts with
Human, Horse, Pig, Dog, Bovine, Rat, Rabbit, Guinea pig, Mouse
Application
WB
$289.00
  pAb ARP33008_P050 Prrx2 Antibody - middle region (ARP33008_P050)
Reacts with
Dog, Human, Rat, Bovine, Pig, Horse, Rabbit, Guinea pig, Mouse
Application
WB
$289.00
  pAb ARP62226_P050 PPP1R16B antibody - N-terminal region (ARP62226_P050)
Reacts with
Mouse, Rat, Dog, Pig, Rabbit, Guinea pig, Bovine, Human
Application
WB
$289.00
  pAb ARP37462_P050 Ptges2 Antibody - middle region (ARP37462_P050)
Reacts with
Rat, Horse, Mouse, Pig, Guinea pig, Bovine, Dog, Human
Application
WB
$289.00
  pAb ARP52340_P050 PSORS1C1 antibody - N-terminal region (ARP52340_P050)
Reacts with
Human
Application
WB
$289.00
  pAb ARP56585_P050 Pfkfb4 antibody - middle region (ARP56585_P050)
Reacts with
Human, Mouse, Dog, Pig, Horse, Rabbit, Rat, Guinea pig, Bovine, Yeast, Zebrafish
Application
WB
$289.00
  pAb ARP39402_P050 PRDM7 Antibody - N-terminal region (ARP39402_P050)
Reacts with
Horse, Rabbit, Pig, Human, Bovine, Rat, Mouse
Application
WB
$289.00
  pAb ARP61895_P050 Pkn2 Antibody - C-terminal region (ARP61895_P050)
Reacts with
Human, Zebrafish, Rat, Bovine, Dog, Pig, Horse, Rabbit, Mouse, Guinea pig, Yeast
Application
WB
$289.00
  pAb ARP62354_P050 Pitpnc1 antibody - middle region (ARP62354_P050)
Reacts with
Human, Pig, Rat, Dog, Horse, Rabbit, Guinea pig, Mouse, Zebrafish
Application
WB
$289.00
  pAb ARP64805_P050 PACS1 antibody - C-terminal region (ARP64805_P050)
Reacts with
Human, Bovine, Dog, Rat, Pig, Horse, Guinea pig, Mouse, Zebrafish, Rabbit
Application
WB
$289.00
  pAb ARP41634_P050 Pcdh10 antibody - C-terminal region (ARP41634_P050)
Reacts with
Rat, Dog, Mouse, Bovine, Rabbit, Guinea pig, Human, Zebrafish
Application
WB
$289.00
  pAb ARP31220_P050 PAX2 Antibody - middle region (ARP31220_P050)
Reacts with
Sheep, Bovine, Dog, Pig, Horse, Zebrafish, Rabbit, Human, Rat, Guinea pig, Mouse
Application
WB
$289.00
  pAb ARP34068_P050 Ppara antibody - C-terminal region (ARP34068_P050)
Reacts with
Human, Horse, Pig, Rabbit, Goat, Mouse, Rat, Bovine, Dog, Zebrafish, Guinea pig, Sheep
Application
WB
$289.00
  pAb ARP31119_P050 PGR Antibody - N-terminal region (ARP31119_P050)
Reacts with
Human, Mouse, Rat, Pig, Yeast, Rabbit, Goat
Application
WB
$289.00
  pAb ARP51233_P050 Phf23 antibody - N-terminal region (ARP51233_P050)
Reacts with
Bovine, Human, Dog, Pig, Rabbit, Rat, Guinea pig, Mouse
Application
WB
$289.00
  pAb ARP34559_P050 PER3 Antibody - C-terminal region (ARP34559_P050)
Reacts with
Human, Dog, Horse, Mouse, Rat, Sheep, Pig, Zebrafish
Application
WB
$289.00
  pAb ARP62420_P050 PPP6C antibody - N-terminal region (ARP62420_P050)
Reacts with
Yeast, Pig, Horse, Rabbit, Rat, Guinea pig, Dog, Human, Bovine, Zebrafish, Mouse, Goat
Application
WB
$289.00
  pAb ARP46119_P050 PLK1 antibody - N-terminal region (ARP46119_P050)
Reacts with
Human, Dog, Horse, Rat, Guinea pig, Bovine, Rabbit, Mouse
Application
WB
$289.00
  pAb ARP61144_P050 Prom1 antibody - N-terminal region (ARP61144_P050)
Reacts with
Human, Guinea pig, Zebrafish, Horse, Rat, Bovine, Dog, Mouse
Application
WB
$289.00
  pAb ARP36287_P050 PRDM6 Antibody - C-terminal region (ARP36287_P050)
Reacts with
Bovine, Rat, Dog, Pig, Horse, Rabbit, Guinea pig, Mouse, Human, Zebrafish
Application
WB
$289.00
  pAb ARP64050_P050 PROKR2 antibody - C-terminal region (ARP64050_P050)
Reacts with
Human, Mouse, Horse, Rabbit, Rat, Dog, Bovine, Guinea pig
Application
WB
$289.00

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Showing 1 - 30 of 284