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Transcription Factor Antibodies

Transcription factors are proteins that regulate gene expression by binding to DNA via one or more DNA-binding domains. This binding is achieved via a combination of electrostatic and van der waals forces and can occur at many closely-related sequences flanking different genes. Once bound to DNA directly or as part of a complex, they can promote or inhibit RNA polymerase recruitment, thereby acting as activators or repressors, respectively. Alternatively, transcription factors can act to recruit coactivators and corepressors or to catalyze histone acetylation and deacetylation. Transcription factors can function downstream of signaling cascades triggered by biological or environmental (ex. hypoxia, hyperthermia) stimuli to alter the expression of target genes. Ligand binding is necessary to activate some transcription factors as this can cause nuclear translocation and changes in the binding affinities for DNA and cofactors. During development, various stimuli can cause transcription factors to up- or down-regulate expression of specific genes at distinct time points to ensure proper development. Transcription factors can function as oncogenes or tumor suppressors and have thus been linked to various cancers. Accordingly, some therapeutic approaches in cancer therapy involve targeting transcription factor families[1].

1. Darnell JE Jr. 2002. Transcription factors as targets for cancer therapy. Nat Rev Cancer. Oct;2(10):740-9.

Transcription Factor Antibodies Top 20 Showcase

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Transcription Factors are involved in transcriptional regulation in the form of up regulation or down regulation acting as either repressors or activators of transcription. We have manufactured more than 3000 antibody products covering almost every known human and mouse transcription factors.

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Showing 1 - 30 of 283
  Type Catalog # Product Product Images Price (USD)
  pAb ARP72403_P050 PCNA Antibody - N-terminal region (ARP72403_P050)
Reacts with
Human
Application
WB
$289.00
  pAb ARP72562_P050 PROX1 Antibody - middle region (ARP72562_P050)
Reacts with
Human
Application
WB
$289.00
  pAb ARP72430_P050 PTRF Antibody - C-terminal region (ARP72430_P050)
Reacts with
Human
Application
WB
$289.00
  pAb ARP38063_P050 PAX6 Antibody - C-terminal region (ARP38063_P050)
Reacts with
Human
Application
WB
$289.00
  pAb ARP58059_P050 PSMD4 Antibody - C-terminal region (ARP58059_P050)
Reacts with
Human, Horse, Rabbit, Dog, Rat, Guinea pig, Sheep, Bovine, Mouse, Zebrafish
Application
WB
$289.00
  pAb ARP33217_P050 PRD12 Antibody - C-terminal region (ARP33217_P050)
Reacts with
Human
Application
WB
$289.00
  pAb ARP34597_P050 PRDM11 Antibody - C-terminal region (ARP34597_P050)
Reacts with
Human, Bovine, Dog, Pig, Mouse, Horse, Rabbit, Rat
Application
WB
$289.00
  pAb ARP63674_P050 PGM2 antibody - C-terminal region (ARP63674_P050)
Reacts with
Human, Dog, Pig, Horse, Guinea pig, Mouse, Rabbit, Rat, Zebrafish, Bovine
Application
WB
$289.00
  pAb ARP64806_P050 PACS1 antibody - C-terminal region (ARP64806_P050)
Reacts with
Human, Bovine, Dog, Rat, Pig, Horse, Rabbit, Guinea pig, Mouse
Application
WB
$289.00
  pAb ARP34180_P050 Pax8 antibody - C-terminal region (ARP34180_P050)
Reacts with
Mouse, Rat, Bovine, Horse, Rabbit, Human, Pig, Dog, Guinea pig
Application
WB
$289.00
  pAb ARP33060_P050 Pou3f1 Antibody - C-terminal region (ARP33060_P050)
Reacts with
Bovine, Dog, Pig, Horse, Rabbit, Guinea pig, Rat, Mouse, Human, Zebrafish
Application
WB
$289.00
  pAb ARP56087_P050 Pepd antibody - middle region (ARP56087_P050)
Reacts with
Mouse, Rat, Dog, Pig, Horse, Rabbit, Guinea pig, Human, Bovine, Zebrafish, Goat
Application
WB
$289.00
  pAb ARP31516_P050 Prdm4 Antibody - C-terminal region (ARP31516_P050)
Reacts with
Rabbit, Rat, Human, Dog, Horse, Yeast, Bovine, Pig, Mouse
Application
WB
$289.00
  pAb ARP53839_P050 Pias2 antibody - N-terminal region (ARP53839_P050)
Reacts with
Dog, Rat, Bovine, Horse, Rabbit, Guinea pig, Human, Mouse, Zebrafish
Application
WB
$289.00
  pAb ARP37243_P050 Ptf1a Antibody - N-terminal region (ARP37243_P050)
Reacts with
Mouse, Bovine, Pig, Rat, Human, Horse, Dog
Application
WB
$289.00
  pAb ARP50680_P050 Plekhf2 antibody - N-terminal region (ARP50680_P050)
Reacts with
Mouse, Rat, Rabbit, Human, Bovine, Horse, Guinea pig
Application
WB
$289.00
  pAb ARP39402_P050 PRDM7 Antibody - N-terminal region (ARP39402_P050)
Reacts with
Horse, Rabbit, Pig, Human, Bovine, Rat, Mouse
Application
WB
$289.00
  pAb ARP50246_P050 Pigu antibody - N-terminal region (ARP50246_P050)
Reacts with
Human, Pig, Dog, Bovine, Horse, Rabbit, Rat, Mouse, Zebrafish, Guinea pig
Application
WB
$289.00
  pAb ARP61895_P050 Pkn2 Antibody - C-terminal region (ARP61895_P050)
Reacts with
Human, Zebrafish, Rat, Bovine, Dog, Pig, Horse, Rabbit, Mouse, Guinea pig, Yeast
Application
WB
$289.00
  pAb ARP62122_P050 Pitpna antibody - C-terminal region (ARP62122_P050)
Reacts with
Human, Dog, Horse, Rabbit, Rat, Pig, Mouse, Bovine, Zebrafish
Application
WB
$289.00
  pAb ARP64105_P050 PEX13 antibody - C-terminal region (ARP64105_P050)
Reacts with
Human, Dog, Pig, Horse, Rabbit, Guinea pig, Mouse, Rat
Application
WB
$289.00
  pAb ARP40189_P050 Prmt6 antibody - C-terminal region (ARP40189_P050)
Reacts with
Dog, Horse, Rat, Guinea pig, Bovine, Human, Mouse
Application
WB
$289.00
  pAb ARP58238_P050 PHLDA2 antibody - N-terminal region (ARP58238_P050)
Reacts with
Human, Bovine, Rat, Pig, Horse, Guinea pig
Application
WB
$289.00
  pAb ARP57888_P050 Pou3f3 Antibody - C-terminal region (ARP57888_P050)
Reacts with
Rat, Pig, Human, Mouse, Dog
Application
WB
$289.00
  pAb ARP34179_P050 PAX8 Antibody - C-terminal region (ARP34179_P050)
Reacts with
Bovine, Horse, Pig, Dog, Human, Mouse, Rat, Guinea pig
Application
WB
$289.00
  pAb ARP62355_P050 PROSC antibody - C-terminal region (ARP62355_P050)
Reacts with
Human, Rat, Guinea pig, Dog, Mouse
Application
WB
$289.00
  pAb ARP42369_P050 PPP2R3B antibody - N-terminal region (ARP42369_P050)
Reacts with
Human
Application
WB
$289.00
  pAb ARP56720_P050 Pskh1 antibody - C-terminal region (ARP56720_P050)
Reacts with
Dog, Horse, Rabbit, Rat, Guinea pig, Human, Bovine, Mouse, Zebrafish
Application
WB
$289.00
  pAb ARP36287_P050 PRDM6 Antibody - C-terminal region (ARP36287_P050)
Reacts with
Bovine, Rat, Dog, Pig, Horse, Rabbit, Guinea pig, Mouse, Human, Zebrafish
Application
WB
$289.00
  pAb ARP64048_P050 PRKAG3 antibody - N-terminal region (ARP64048_P050)
Reacts with
Human
Application
WB
$289.00

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Showing 1 - 30 of 283