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Now Offering Over 48,216 Antibodies & 21,887 Antigens!

Transcription Factor Antibodies

Transcription factors are proteins that regulate gene expression by binding to DNA via one or more DNA-binding domains. This binding is achieved via a combination of electrostatic and van der waals forces and can occur at many closely-related sequences flanking different genes. Once bound to DNA directly or as part of a complex, they can promote or inhibit RNA polymerase recruitment, thereby acting as activators or repressors, respectively. Alternatively, transcription factors can act to recruit coactivators and corepressors or to catalyze histone acetylation and deacetylation. Transcription factors can function downstream of signaling cascades triggered by biological or environmental (ex. hypoxia, hyperthermia) stimuli to alter the expression of target genes. Ligand binding is necessary to activate some transcription factors as this can cause nuclear translocation and changes in the binding affinities for DNA and cofactors. During development, various stimuli can cause transcription factors to up- or down-regulate expression of specific genes at distinct time points to ensure proper development. Transcription factors can function as oncogenes or tumor suppressors and have thus been linked to various cancers. Accordingly, some therapeutic approaches in cancer therapy involve targeting transcription factor families[1].

1. Darnell JE Jr. 2002. Transcription factors as targets for cancer therapy. Nat Rev Cancer. Oct;2(10):740-9.

Transcription Factor Antibodies Top 20 Showcase

View the entire product list by clicking here.

ARP46323_CENP-M CENPM Antibody
ARP57258_CENP-N CENPN Antibody
ARP30312_TP53 TP53 Antibody
ARP38253_P050-STAT3-IHC-01 STAT3 Antibody
ARP37894_P050_TGF-beta-1 TGFB1 Antibody
ARP30947_PAX7_IF_image_01 PAX7 Antibody
ARP41404_CYP1A1_IHC_image_01 CYP1A1 Antibody
ARP33326_SOX10 SOX10 Antibody
ARP45222_P050_HMOX1_WB_imag HMOX1 Antibody
ARP32548-p50-GATA3-IF-img-0 GATA3 Antibody
ARP32372-HES1-WB-01 HES1 Antibody
ARP37018-ATF4-IF-image-01 ATF4 Antibody
ARP48127_CD36 CD36 Antibody
ARP31400-TFAM-WB-04 TFAM Antibody
ARP32752_OLIG2 Nterm OLIG2 N term Antibody
ARP31859-p50-GATA6-IF-img-02 GATA6 Antibody
ARP33090_T100_MMP9 MMP9 Antibody
AVARP20016_T100_MMP-2 MMP2 Antibody
AVARP20010_KDR KDR Antibody
ARP41456-MUC1-IHC-image-01 MUC1 Antibody

Polyclonal Antibody - Transcription Factors

Transcription Factors are involved in transcriptional regulation in the form of up regulation or down regulation acting as either repressors or activators of transcription. We have manufactured more than 3000 antibody products covering almost every known human and mouse transcription factors.

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Showing 1 - 30 of 40
  Type Catalog # Product Product Images Price (USD)
  pAb ARP31414_P050 OTX2 antibody - middle region (ARP31414_P050)
Reacts with
Bovine, Dog, Guinea pig, Human, Rabbit, Rat, Sheep, African clawed frog, Chicken, Mouse, Zebrafish
Application
WB
 $289.00
  pAb ARP31464_P050 OLIG2 antibody - N-terminal region (ARP31464_P050)
Reacts with
Chicken, Guinea pig, Human, Mouse, Rat
Application
WB, IHC
 $289.00
  pAb ARP31539_P050 OSR2 antibody - N-terminal region (ARP31539_P050)
Reacts with
Human, African clawed frog, Bovine, Dog, Guinea pig, Horse, Mouse, Pig, Rabbit, Rat, Chicken
Application
WB
 $289.00
  pAb ARP32292_P050 OPTN antibody - N-terminal region (ARP32292_P050)
Reacts with
Human, Horse, Rabbit, Rat, Pig, Bovine, Dog, Mouse
Application
WB
 $289.00
  pAb ARP32396_P050 OTX1 antibody - middle region (ARP32396_P050)
Reacts with
Human, Dog, Mouse, Rabbit, Bovine, Guinea pig, Rat
Application
WB
 $289.00
  pAb ARP32439_P050 OTX2 antibody - N-terminal region (ARP32439_P050)
Reacts with
Bovine, Chicken, Dog, Guinea pig, Human, Mouse, Rabbit, Rat, Sheep, Zebrafish, African clawed frog
Application
WB, IHC
 $289.00
  pAb ARP32440_P050 OTX2 antibody - middle region (ARP32440_P050)
Reacts with
African clawed frog, Bovine, Dog, Guinea pig, Human, Rabbit, Rat, Sheep, Chicken, Mouse, Zebrafish
Application
WB
 $289.00
  pAb ARP32752_P050 OLIG2 antibody - N-terminal region (ARP32752_P050)
Reacts with
Human, Mouse, Rat, Guinea pig
Application
WB, IHC
 $289.00
  pAb ARP32753_P050 OLIG2 Antibody - C-terminal region (ARP32753_P050)
Reacts with
Human, Guinea pig, Mouse, Rat, Chicken
Application
WB, IHC
 $289.00
  pAb ARP33204_P050 OVOL2 antibody - middle region (ARP33204_P050)
Reacts with
Bovine, Dog, Horse, Human, Mouse, Pig, Rabbit, Rat, Chicken
Application
WB
 $289.00
  pAb ARP34594_P050 OTUD7B antibody - middle region (ARP34594_P050)
Reacts with
Bovine, Dog, Guinea pig, Human, Mouse, Pig, Rat
Application
WB
 $289.00
  pAb ARP34633_P050 OTP antibody - N-terminal region (ARP34633_P050)
Reacts with
Bovine, Dog, Guinea pig, Horse, Human, Mouse, Rabbit, Rat, Chicken, Zebrafish
Application
WB
 $289.00
  pAb ARP35750_T100 ONECUT2 antibody - middle region (ARP35750_T100)
Reacts with
Dog, Guinea pig, Horse, Mouse, Pig, Rabbit
Application
WB, IHC
 $229.00
  pAb ARP36247_P050 Olig3 antibody - N-terminal region (ARP36247_P050)
Reacts with
Bovine, Dog, Human, Mouse, Rabbit, Rat, Horse
Application
WB
 $289.00
  pAb ARP37480_P050 Onecut3 antibody - C-terminal region (ARP37480_P050)
Reacts with
Bovine, Dog, Pig, Zebrafish
Application
WB
 $289.00
  pAb ARP37481_P050 Onecut3 antibody - C-terminal region (ARP37481_P050)
Reacts with
Application
WB
 $289.00
  pAb ARP37740_P050 ONECUT2 antibody - N-terminal region (ARP37740_P050)
Reacts with
Guinea pig, Pig, Mouse
Application
WB
 $289.00
  pAb ARP39102_P050 OTX1 antibody - N-terminal region (ARP39102_P050)
Reacts with
African clawed frog, Bovine, Dog, Guinea pig, Human, Mouse, Rabbit, Rat, Zebrafish
Application
WB
 $289.00
  pAb ARP39103_T100 OTX1 antibody - C-terminal region (ARP39103_T100)
Reacts with
Bovine, Dog, Human, Mouse, Rat, Zebrafish
Application
WB
 $229.00
  pAb ARP39499_P050 OVOL2 antibody - N-terminal region (ARP39499_P050)
Reacts with
Bovine, Dog, Horse, Human, Pig, Rabbit, Mouse, Rat
Application
WB, IF
 $289.00
  pAb ARP39500_P050 OVOL2 antibody - middle region (ARP39500_P050)
Reacts with
Human
Application
WB, IF
 $289.00
  pAb ARP39525_P050 OPTN antibody - N-terminal region (ARP39525_P050)
Reacts with
Human, Bovine, Horse, Dog, Pig
Application
WB
 $289.00
  pAb ARP39678_P050 OTP antibody - N-terminal region (ARP39678_P050)
Reacts with
Bovine, Dog, Guinea pig, Horse, Human, Mouse, Rabbit, Rat, Zebrafish
Application
WB
 $289.00
  pAb ARP39679_P050 OTP antibody - C-terminal region (ARP39679_P050)
Reacts with
Bovine, Chicken, Dog, Guinea pig, Human, Mouse, Rat, Zebrafish
Application
WB
 $289.00
  pAb ARP40402_P050 Oas1g antibody - N-terminal region (ARP40402_P050)
Reacts with
Mouse
Application
WB
 $289.00
  pAb ARP41767_P050 Otc antibody - C-terminal region (ARP41767_P050)
Reacts with
Bovine, Chicken, Dog, Horse, Human, Mouse, Pig, Rabbit, Rat, African clawed frog, Guinea pig, Sheep, Zebrafish
Application
WB
 $289.00
  pAb ARP42889_P050 OCLN antibody - N-terminal region (ARP42889_P050)
Reacts with
Bovine, Dog, Guinea pig, Horse, Human, Mouse, Pig, Rabbit, Rat, African clawed frog, Zebrafish
Application
WB
 $289.00
  pAb ARP43601_P050 OPTN antibody - C-terminal region (ARP43601_P050)
Reacts with
Dog, Horse, Human, Mouse, Rabbit, Rat, African clawed frog, Bovine, Pig, Chicken, Zebrafish
Application
WB
 $289.00
  pAb ARP44255_P050 OCA2 antibody - middle region (ARP44255_P050)
Reacts with
Bovine, Dog, Guinea pig, Horse, Pig, Rabbit, Chicken, Zebrafish
Application
WB
 $289.00
  pAb ARP48661_P050 Oxsr1 antibody - middle region (ARP48661_P050)
Reacts with
Bovine, Dog, Horse, Human, Pig, Rat, African clawed frog, Mouse, Zebrafish, Chicken
Application
WB
 $289.00

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Showing 1 - 30 of 40

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