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Now Offering Over 48,216 Antibodies & 21,887 Antigens!

Transcription Factor Antibodies

Transcription factors are proteins that regulate gene expression by binding to DNA via one or more DNA-binding domains. This binding is achieved via a combination of electrostatic and van der waals forces and can occur at many closely-related sequences flanking different genes. Once bound to DNA directly or as part of a complex, they can promote or inhibit RNA polymerase recruitment, thereby acting as activators or repressors, respectively. Alternatively, transcription factors can act to recruit coactivators and corepressors or to catalyze histone acetylation and deacetylation. Transcription factors can function downstream of signaling cascades triggered by biological or environmental (ex. hypoxia, hyperthermia) stimuli to alter the expression of target genes. Ligand binding is necessary to activate some transcription factors as this can cause nuclear translocation and changes in the binding affinities for DNA and cofactors. During development, various stimuli can cause transcription factors to up- or down-regulate expression of specific genes at distinct time points to ensure proper development. Transcription factors can function as oncogenes or tumor suppressors and have thus been linked to various cancers. Accordingly, some therapeutic approaches in cancer therapy involve targeting transcription factor families[1].

1. Darnell JE Jr. 2002. Transcription factors as targets for cancer therapy. Nat Rev Cancer. Oct;2(10):740-9.

Transcription Factor Antibodies Top 20 Showcase

View the entire product list by clicking here.

ARP46323_CENP-M CENPM Antibody
ARP57258_CENP-N CENPN Antibody
ARP30312_TP53 TP53 Antibody
ARP38253_P050-STAT3-IHC-01 STAT3 Antibody
ARP37894_P050_TGF-beta-1 TGFB1 Antibody
ARP30947_PAX7_IF_image_01 PAX7 Antibody
ARP41404_CYP1A1_IHC_image_01 CYP1A1 Antibody
ARP33326_SOX10 SOX10 Antibody
ARP45222_P050_HMOX1_WB_imag HMOX1 Antibody
ARP32548-p50-GATA3-IF-img-0 GATA3 Antibody
ARP32372-HES1-WB-01 HES1 Antibody
ARP37018-ATF4-IF-image-01 ATF4 Antibody
ARP48127_CD36 CD36 Antibody
ARP31400-TFAM-WB-04 TFAM Antibody
ARP32752_OLIG2 Nterm OLIG2 N term Antibody
ARP31859-p50-GATA6-IF-img-02 GATA6 Antibody
ARP33090_T100_MMP9 MMP9 Antibody
AVARP20016_T100_MMP-2 MMP2 Antibody
AVARP20010_KDR KDR Antibody
ARP41456-MUC1-IHC-image-01 MUC1 Antibody

Polyclonal Antibody - Transcription Factors

Transcription Factors are involved in transcriptional regulation in the form of up regulation or down regulation acting as either repressors or activators of transcription. We have manufactured more than 3000 antibody products covering almost every known human and mouse transcription factors.

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Showing 1 - 30 of 196
  Type Catalog # Product Product Images Price (USD)
  pAb ARP30077_P050 MIXL1 antibody - N-terminal region (ARP30077_P050)
Reacts with
Human
Application
WB
 $289.00
  pAb ARP30089_T100 MXD3 antibody - N-terminal region (ARP30089_T100)
Reacts with
Human, Bovine, Dog, Pig
Application
WB
 $229.00
  pAb ARP30292_P050 MYC antibody - N-terminal region (ARP30292_P050)
Reacts with
African clawed frog, Bovine, Chicken, Dog, Guinea pig, Human, Mouse, Pig, Rabbit, Rat, Sheep, Zebrafish
Application
WB
 $289.00
  pAb ARP30649_T100 MAP3K8 antibody - C-terminal region (ARP30649_T100)
Reacts with
Bovine, Dog, Horse, Human, Rat, Mouse, Chicken, Rabbit
Application
WB
 $229.00
  pAb ARP30650_P050 MAP3K8 antibody - N-terminal region (ARP30650_P050)
Reacts with
Human, Horse, Mouse, Bovine
Application
WB
 $289.00
  pAb ARP31396_T100 MSX1 antibody - middle region (ARP31396_T100)
Reacts with
Bovine, Dog, Guinea pig, Human, Pig, Mouse, Rat
Application
WB, IHC
 $229.00
  pAb ARP31398_P050 MSX2 antibody - N-terminal region (ARP31398_P050)
Reacts with
Bovine, Dog, Human, Mouse
Application
WB
 $289.00
  pAb ARP31402_P050 MXI1 antibody - middle region (ARP31402_P050)
Reacts with
Bovine, Chicken, Dog, Human, Mouse, Pig, Rabbit, Rat, African clawed frog, Zebrafish
Application
WB
 $289.00
  pAb ARP31403_P050 MXI1 antibody - middle region (ARP31403_P050)
Reacts with
Bovine, Dog, Human, Mouse, Pig, Rabbit, Rat, Chicken, Zebrafish
Application
WB, IHC
 $289.00
  pAb ARP31406_P050 MYF5 antibody - C-terminal region (ARP31406_P050)
Reacts with
Bovine, Dog, Goat, Human, Pig
Application
WB
 $289.00
  pAb ARP31409_P050 MYF6 antibody - middle region (ARP31409_P050)
Reacts with
Bovine, Goat, Human, Pig, Sheep, Dog, Mouse, Rat
Application
WB
 $289.00
  pAb ARP31452_P050 MED16 antibody - N-terminal region (ARP31452_P050)
Reacts with
Bovine, Dog, Guinea pig, Human, Mouse, Pig, Rat, Chicken, African clawed frog
Application
WB
 $289.00
  pAb ARP31518_P050 MYST2 antibody - N-terminal region (ARP31518_P050)
Reacts with
Horse, Mouse, Pig, Rat, African clawed frog, Chicken
Application
WB
 $289.00
  pAb ARP31860_P050 MYCBP antibody - middle region (ARP31860_P050)
Reacts with
Guinea pig, Human, Bovine, Chicken, Dog, Mouse, Pig
Application
WB, IHC
 $289.00
  pAb ARP31860_T100 MYCBP antibody - middle region (ARP31860_T100)
Reacts with
Guinea pig, Human, Bovine, Chicken, Dog, Mouse, Pig
Application
WB, IHC
 $229.00
  pAb ARP31887_P050 MKX antibody - middle region (ARP31887_P050)
Reacts with
African clawed frog, Bovine, Chicken, Dog, Human, Rabbit, Mouse, Rat
Application
WB
 $289.00
  pAb ARP31938_P050 MNX1 antibody - N-terminal region (ARP31938_P050)
Reacts with
Human, Pig, Dog, Mouse
Application
WB
 $289.00
  pAb ARP32010_P050 Mafg Antibody - N-terminal region (ARP32010_P050)
Reacts with
Application
WB
 $289.00
  pAb ARP32012_P050 MBD1 antibody - C-terminal region (ARP32012_P050)
Reacts with
Bovine, Dog, Guinea pig, Horse, Human, Pig, Rabbit, Mouse, Rat
Application
WB
 $289.00
  pAb ARP32016_T100 MEFV antibody - N-terminal region (ARP32016_T100)
Reacts with
Bovine, Dog, Guinea pig, Human, Mouse, Horse
Application
WB
 $229.00
  pAb ARP32017_P050 MEIS1 antibody - middle region (ARP32017_P050)
Reacts with
Bovine, Chicken, Dog, Guinea pig, Horse, Human, Rabbit, Mouse, Zebrafish, African clawed frog, Rat
Application
WB
 $289.00
  pAb ARP32027_T100 MTF1 antibody - C-terminal region (ARP32027_T100)
Reacts with
Bovine, Dog, Horse, Human, Mouse, Rat, Guinea pig, Rabbit
Application
WB
 $229.00
  pAb ARP32028_P050 MYBL1 antibody - middle region (ARP32028_P050)
Reacts with
Dog, Human, Pig, Bovine, Chicken, Guinea pig, Horse, Mouse, Rabbit, Rat
Application
WB
 $289.00
  pAb ARP32030_T100 MYCN antibody - C-terminal region (ARP32030_T100)
Reacts with
Bovine, Dog, Horse, Human, Rat, Mouse
Application
WB
 $229.00
  pAb ARP32065_P050 MYEF2 antibody - N-terminal region (ARP32065_P050)
Reacts with
Human, Guinea pig, Mouse, Rabbit, Rat, Pig, Bovine, Horse, Dog
Application
WB
 $289.00
  pAb ARP32134_P050 MYF5 antibody - N-terminal region (ARP32134_P050)
Reacts with
Bovine, Chicken, Goat, Human, Mouse, Pig, Rat, Sheep, Dog, African clawed frog, Zebrafish
Application
WB
 $289.00
  pAb ARP32135_P050 MYF6 antibody - N-terminal region (ARP32135_P050)
Reacts with
African clawed frog, Bovine, Chicken, Dog, Goat, Human, Mouse, Pig, Rat, Sheep, Zebrafish
Application
WB, IHC
 $289.00
  pAb ARP32402_P050 MAP3K7IP2 antibody - N-terminal region (ARP32402_P050)
Reacts with
Mouse, Bovine, Dog, Rat, Human, Chicken
Application
WB, IHC
 $289.00
  pAb ARP32485_P050 MBD2 antibody - N-terminal region (ARP32485_P050)
Reacts with
Human, Mouse, Rat
Application
WB
 $289.00
  pAb ARP32543_P050 MIZF antibody - middle region (ARP32543_P050)
Reacts with
Rat, Zebrafish
Application
WB
 $289.00

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Showing 1 - 30 of 196

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