website statistics

Aviva Systems Biology

Account Login 

Aviva's office will be closed on 4/18/2014 for Good Friday holiday. Please go here for more info.

Now Offering Over 85,203 Antibodies & 34,301 Antigens!

Transcription Factor Antibodies

Transcription factors are proteins that regulate gene expression by binding to DNA via one or more DNA-binding domains. This binding is achieved via a combination of electrostatic and van der waals forces and can occur at many closely-related sequences flanking different genes. Once bound to DNA directly or as part of a complex, they can promote or inhibit RNA polymerase recruitment, thereby acting as activators or repressors, respectively. Alternatively, transcription factors can act to recruit coactivators and corepressors or to catalyze histone acetylation and deacetylation. Transcription factors can function downstream of signaling cascades triggered by biological or environmental (ex. hypoxia, hyperthermia) stimuli to alter the expression of target genes. Ligand binding is necessary to activate some transcription factors as this can cause nuclear translocation and changes in the binding affinities for DNA and cofactors. During development, various stimuli can cause transcription factors to up- or down-regulate expression of specific genes at distinct time points to ensure proper development. Transcription factors can function as oncogenes or tumor suppressors and have thus been linked to various cancers. Accordingly, some therapeutic approaches in cancer therapy involve targeting transcription factor families[1].

1. Darnell JE Jr. 2002. Transcription factors as targets for cancer therapy. Nat Rev Cancer. Oct;2(10):740-9.

Transcription Factor Antibodies Top 20 Showcase

View the entire product list by clicking here.

Transcription Factors are involved in transcriptional regulation in the form of up regulation or down regulation acting as either repressors or activators of transcription. We have manufactured more than 3000 antibody products covering almost every known human and mouse transcription factors.

Page of 8

Showing 1 - 30 of 217
  Type Catalog # Product Product Images Price (USD)
  pAb ARP30019_P050 MINA Antibody - C-terminal region (ARP30019_P050)
Reacts with
Human, Rabbit, Rat, Dog, Pig
Application
WB
$289.00
  pAb ARP30077_P050 MIXL1 antibody - N-terminal region (ARP30077_P050)
Reacts with
Human
Application
WB
$289.00
  pAb ARP30089_T100 MXD3 antibody - N-terminal region (ARP30089_T100)
Reacts with
Human, Bovine, Horse, Rat, Dog, Pig, Rabbit, Mouse
Application
WB
$229.00
  pAb ARP30292_P050 MYC antibody - N-terminal region (ARP30292_P050)
Reacts with
Zebrafish, Mouse, Human, Rat, Pig, Dog, Horse, Rabbit, Guinea pig, Sheep, Bovine
Application
WB
$289.00
  pAb ARP30544_T100 MAP2K4 Antibody - C-terminal region (ARP30544_T100)
Reacts with
Human
Application
WB
$229.00
  pAb ARP30649_T100 MAP3K8 antibody - C-terminal region (ARP30649_T100)
Reacts with
Bovine, Human, Dog, Horse, Rat, Guinea pig, Mouse, Rabbit
Application
WB
$229.00
  pAb ARP30650_P050 MAP3K8 antibody - N-terminal region (ARP30650_P050)
Reacts with
Human, Horse, Mouse, Bovine
Application
WB
$289.00
  pAb ARP30936_P050 MYB Antibody - C-terminal region (ARP30936_P050)
Reacts with
Human, Pig, Dog
Application
WB
$289.00
  pAb ARP31212_P050 MITF Antibody - middle region (ARP31212_P050)
Reacts with
Human, Pig, Bovine, Horse, Rabbit, Rat, Guinea pig, Dog, Sheep, Mouse
Application
WB
$289.00
  pAb ARP31396_T100 MSX1 antibody - middle region (ARP31396_T100)
Reacts with
Human, Pig, Bovine, Dog, Horse, Rat, Guinea pig, Mouse
Application
IHC, WB
$229.00
  pAb ARP31398_P050 MSX2 antibody - N-terminal region (ARP31398_P050)
Reacts with
Human, Horse, Bovine, Dog, Rabbit, Mouse, Rat
Application
IF, WB
$289.00
  pAb ARP31402_P050 MXI1 antibody - middle region (ARP31402_P050)
Reacts with
Human, Dog, Rabbit, Rat, Guinea pig, Mouse, Bovine, Yeast, Horse, Zebrafish
Application
WB
$289.00
  pAb ARP31403_P050 MXI1 antibody - middle region (ARP31403_P050)
Reacts with
Human, Dog, Rabbit, Rat, Guinea pig, Mouse, Bovine, Zebrafish, Yeast
Application
IHC, WB
$289.00
  pAb ARP31406_P050 MYF5 antibody - C-terminal region (ARP31406_P050)
Reacts with
Pig, Horse, Rabbit, Goat, Guinea pig, Human, Bovine, Dog, Rat
Application
WB
$289.00
  pAb ARP31409_P050 MYF6 antibody - middle region (ARP31409_P050)
Reacts with
Sheep, Goat, Horse, Human, Bovine, Pig, Rabbit, Rat, Guinea pig, Dog, Mouse
Application
WB
$289.00
  pAb ARP31452_P050 MED16 antibody - N-terminal region (ARP31452_P050)
Reacts with
Human, Rat, Dog, Mouse, Pig, Bovine, Guinea pig, Horse
Application
WB
$289.00
  pAb ARP31510_P050 MORF4L1 Antibody - C-terminal region (ARP31510_P050)
Reacts with
Mouse, Human, Bovine, Zebrafish, Dog, Pig, Horse, Rabbit, Rat, Guinea pig
Application
WB
$289.00
  pAb ARP31518_P050 MYST2 antibody - N-terminal region (ARP31518_P050)
Reacts with
Rat, Pig, Dog, Horse, Rabbit, Guinea pig, Human, Bovine, Mouse
Application
WB
$289.00
  pAb ARP31860_P050 MYCBP antibody - middle region (ARP31860_P050)
Reacts with
Rat, Guinea pig, Human, Horse, Rabbit, Dog, Bovine, Mouse
Application
IHC, WB
$289.00
  pAb ARP31860_T100 MYCBP antibody - middle region (ARP31860_T100)
Reacts with
Rat, Guinea pig, Human, Horse, Rabbit, Dog, Bovine, Mouse
Application
IHC, WB
$229.00
  pAb ARP31887_P050 MKX antibody - middle region (ARP31887_P050)
Reacts with
Bovine, Dog, Horse, Rabbit, Rat, Guinea pig, Human, Mouse, Zebrafish
Application
WB
$289.00
  pAb ARP31938_P050 MNX1 antibody - N-terminal region (ARP31938_P050)
Reacts with
Human, Pig, Dog, Mouse, Rat
Application
WB
$289.00
  pAb ARP32010_P050 Mafg Antibody - N-terminal region (ARP32010_P050)
Reacts with
Bovine, Dog, Zebrafish, Horse, Rat, Guinea pig, Human, Mouse
Application
WB
$289.00
  pAb ARP32012_P050 MBD1 antibody - C-terminal region (ARP32012_P050)
Reacts with
Human, Dog, Pig, Horse, Rabbit, Rat, Guinea pig, Bovine, Mouse
Application
WB
$289.00
  pAb ARP32016_T100 MEFV antibody - N-terminal region (ARP32016_T100)
Reacts with
Human, Bovine, Dog, Pig, Rabbit, Rat, Guinea pig, Mouse, Horse
Application
WB
$229.00
  pAb ARP32017_P050 MEIS1 antibody - middle region (ARP32017_P050)
Reacts with
Bovine, Human, Dog, Pig, Horse, Rabbit, Rat, Guinea pig, Mouse, Zebrafish
Application
WB
$289.00
  pAb ARP32018_P050 MEOX1 Antibody - C-terminal region (ARP32018_P050)
Reacts with
Pig, Bovine, Human, Dog, Horse, Rabbit, Guinea pig, Rat, Mouse
Application
WB
$289.00
  pAb ARP32027_T100 MTF1 antibody - C-terminal region (ARP32027_T100)
Reacts with
Human, Rat, Dog, Horse, Mouse, Bovine, Rabbit, Guinea pig
Application
WB
$229.00
  pAb ARP32028_P050 MYBL1 antibody - middle region (ARP32028_P050)
Reacts with
Pig, Dog, Human, Rat, Bovine, Mouse, Horse, Rabbit, Guinea pig
Application
WB
$289.00
  pAb ARP32030_T100 MYCN antibody - C-terminal region (ARP32030_T100)
Reacts with
Human, Bovine, Dog, Horse, Mouse, Pig, Rat, Rabbit
Application
WB
$229.00

Page of 8

Showing 1 - 30 of 217