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Now Offering Over 85,203 Antibodies & 34,301 Antigens!

Transcription Factor Antibodies

Transcription factors are proteins that regulate gene expression by binding to DNA via one or more DNA-binding domains. This binding is achieved via a combination of electrostatic and van der waals forces and can occur at many closely-related sequences flanking different genes. Once bound to DNA directly or as part of a complex, they can promote or inhibit RNA polymerase recruitment, thereby acting as activators or repressors, respectively. Alternatively, transcription factors can act to recruit coactivators and corepressors or to catalyze histone acetylation and deacetylation. Transcription factors can function downstream of signaling cascades triggered by biological or environmental (ex. hypoxia, hyperthermia) stimuli to alter the expression of target genes. Ligand binding is necessary to activate some transcription factors as this can cause nuclear translocation and changes in the binding affinities for DNA and cofactors. During development, various stimuli can cause transcription factors to up- or down-regulate expression of specific genes at distinct time points to ensure proper development. Transcription factors can function as oncogenes or tumor suppressors and have thus been linked to various cancers. Accordingly, some therapeutic approaches in cancer therapy involve targeting transcription factor families[1].

1. Darnell JE Jr. 2002. Transcription factors as targets for cancer therapy. Nat Rev Cancer. Oct;2(10):740-9.

Transcription Factor Antibodies Top 20 Showcase

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Transcription Factors are involved in transcriptional regulation in the form of up regulation or down regulation acting as either repressors or activators of transcription. We have manufactured more than 3000 antibody products covering almost every known human and mouse transcription factors.

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Showing 1 - 30 of 229
  Type Catalog # Product Product Images Price (USD)
  pAb ARP72678_P050 MAP3K7 Antibody - C-terminal region (ARP72678_P050)
Reacts with
Human
Application
WB
$289.00
  pAb ARP75251_P050 MED17 Antibody - middle region (ARP75251_P050)
Reacts with
Human
Application
WB
$289.00
  pAb ARP75584_P050 MED15 Antibody - C-terminal region (ARP75584_P050)
Reacts with
Human
Application
WB
$289.00
  pAb ARP51650_P050 MLX Antibody - N-terminal region (ARP51650_P050)
Reacts with
Human
Application
WB
$289.00
  pAb ARP72516_P050 MAF Antibody - C-terminal region (ARP72516_P050)
Reacts with
Human
Application
WB
$289.00
  pAb ARP75292_P050 MAML1 Antibody - middle region (ARP75292_P050)
Reacts with
Human
Application
WB
$289.00
  pAb ARP30544_T100 MAP2K4 Antibody - C-terminal region (ARP30544_T100)
Reacts with
Human
Application
WB
$229.00
  pAb ARP74648_P050 MTA2 Antibody - C-terminal region (ARP74648_P050)
Reacts with
Human
Application
WB
$289.00
  pAb ARP74059_P050 MEF2C Antibody - middle region (ARP74059_P050)
Reacts with
Human
Application
WB
$289.00
  pAb ARP75323_P050 MAMD1 Antibody - C-terminal region (ARP75323_P050)
Reacts with
Human
Application
WB
$289.00
  pAb ARP32704_P050 MNT Antibody - C-terminal region (ARP32704_P050)
Reacts with
Cow; Dog; Guinea Pig; Horse; Human; Mouse; Rabbit; Zebrafish
Application
WB
$289.00
  pAb ARP50514_P050 MDFI Antibody - middle region (ARP50514_P050)
Reacts with
Cow; Dog; Human; Pig; Rabbit; Sheep
Application
WB
$289.00
  pAb ARP56437_P050 MK11 Antibody - N-terminal region (ARP56437_P050)
Reacts with
Cow; Human; Mouse; Rat; Zebrafish
Application
WB
$289.00
  pAb ARP74056_P050 MECP2 Antibody - N-terminal region (ARP74056_P050)
Reacts with
Human
Application
WB
$289.00
  pAb ARP58372_P050 MFSD3 Antibody - N-terminal region (ARP58372_P050)
Reacts with
Human; Pig
Application
WB
$289.00
  pAb ARP33721_T100 MORF4L2 antibody - N-terminal region (ARP33721_T100)
Reacts with
Cow; Dog; Guinea Pig; Horse; Human; Mouse; Pig; Rabbit; Rat
Application
IHC, WB
$229.00
  pAb ARP33720_T100 MORF4L2 antibody - N-terminal region (ARP33720_T100)
Reacts with
Cow; Dog; Guinea Pig; Horse; Human; Mouse; Pig; Rabbit; Rat; Yeast
Application
IHC, WB
$229.00
  pAb ARP57928_P050 MED16 Antibody - middle region (ARP57928_P050)
Reacts with
Cow; Dog; Guinea Pig; Horse; Human; Mouse; Rat; Zebrafish
Application
WB
$289.00
  pAb ARP59878_P050 MAGEA12 antibody - N-terminal region (ARP59878_P050)
Reacts with
Human
Application
WB
$289.00
  pAb ARP30019_P050 MINA Antibody - C-terminal region (ARP30019_P050)
Reacts with
Dog; Human; Pig; Rabbit; Rat
Application
WB
$289.00
  pAb ARP34591_P050 METTL3 antibody - C-terminal region (ARP34591_P050)
Reacts with
Cow; Dog; Goat; Guinea Pig; Horse; Human; Mouse; Rabbit; Rat; Zebrafish
Application
WB
$289.00
  pAb ARP32693_P050 MBD1 antibody - C-terminal region (ARP32693_P050)
Reacts with
Cow; Dog; Guinea Pig; Horse; Human; Rabbit; Rat
Application
WB
$289.00
  pAb ARP37299_P050 Mlxipl Antibody - N-terminal region (ARP37299_P050)
Reacts with
Cow; Dog; Guinea Pig; Horse; Human; Mouse; Pig; Rabbit; Rat
Application
WB
$289.00
  pAb ARP45395_P050 Mfng antibody - middle region (ARP45395_P050)
Reacts with
Cow; Dog; Guinea Pig; Horse; Human; Mouse; Rabbit; Rat; Zebrafish
Application
WB
$289.00
  pAb ARP39664_P050 MXD3 Antibody - C-terminal region (ARP39664_P050)
Reacts with
Cow; Dog; Guinea Pig; Horse; Human; Mouse; Pig; Rabbit; Rat; Zebrafish
Application
WB
$289.00
  pAb ARP49192_P050 Mgat5b antibody - C-terminal region (ARP49192_P050)
Reacts with
Cow; Dog; Guinea Pig; Horse; Human; Mouse; Rat; Zebrafish
Application
WB
$289.00
  pAb ARP55596_P050 MED19 Antibody - middle region (ARP55596_P050)
Reacts with
Cow; Dog; Guinea Pig; Horse; Human; Mouse; Rabbit; Rat; Zebrafish
Application
WB, CHIP
$289.00
  pAb ARP64144_P050 MAGED1 antibody - C-terminal region (ARP64144_P050)
Reacts with
Cow; Dog; Goat; Guinea Pig; Horse; Human; Mouse; Rabbit; Rat
Application
WB
$289.00
  pAb ARP64778_P050 MMP28 antibody - C-terminal region (ARP64778_P050)
Reacts with
Cow; Dog; Horse; Human
Application
WB
$289.00
  pAb ARP69130_P050 MEX3A Antibody - N-terminal region (ARP69130_P050)
Reacts with
Cow; Dog; Guinea Pig; Horse; Human; Mouse; Rabbit; Rat
Application
WB
$289.00

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Showing 1 - 30 of 229