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Now Offering Over 85,203 Antibodies & 34,301 Antigens!

Transcription Factor Antibodies

Transcription factors are proteins that regulate gene expression by binding to DNA via one or more DNA-binding domains. This binding is achieved via a combination of electrostatic and van der waals forces and can occur at many closely-related sequences flanking different genes. Once bound to DNA directly or as part of a complex, they can promote or inhibit RNA polymerase recruitment, thereby acting as activators or repressors, respectively. Alternatively, transcription factors can act to recruit coactivators and corepressors or to catalyze histone acetylation and deacetylation. Transcription factors can function downstream of signaling cascades triggered by biological or environmental (ex. hypoxia, hyperthermia) stimuli to alter the expression of target genes. Ligand binding is necessary to activate some transcription factors as this can cause nuclear translocation and changes in the binding affinities for DNA and cofactors. During development, various stimuli can cause transcription factors to up- or down-regulate expression of specific genes at distinct time points to ensure proper development. Transcription factors can function as oncogenes or tumor suppressors and have thus been linked to various cancers. Accordingly, some therapeutic approaches in cancer therapy involve targeting transcription factor families[1].

1. Darnell JE Jr. 2002. Transcription factors as targets for cancer therapy. Nat Rev Cancer. Oct;2(10):740-9.

Transcription Factor Antibodies Top 20 Showcase

View the entire product list by clicking here.

Transcription Factors are involved in transcriptional regulation in the form of up regulation or down regulation acting as either repressors or activators of transcription. We have manufactured more than 3000 antibody products covering almost every known human and mouse transcription factors.

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Showing 1 - 30 of 229
  Type Catalog # Product Product Images Price (USD)
  pAb ARP30544_T100 MAP2K4 Antibody - C-terminal region (ARP30544_T100)
Reacts with
Human
Application
WB
$229.00
  pAb ARP74648_P050 MTA2 Antibody - C-terminal region (ARP74648_P050)
Reacts with
Human
Application
WB
$289.00
  pAb ARP74059_P050 MEF2C Antibody - middle region (ARP74059_P050)
Reacts with
Human
Application
WB
$289.00
  pAb ARP75323_P050 MAMD1 Antibody - C-terminal region (ARP75323_P050)
Reacts with
Human
Application
WB
$289.00
  pAb ARP72678_P050 MAP3K7 Antibody - C-terminal region (ARP72678_P050)
Reacts with
Human
Application
WB
$289.00
  pAb ARP75251_P050 MED17 Antibody - middle region (ARP75251_P050)
Reacts with
Human
Application
WB
$289.00
  pAb ARP75584_P050 MED15 Antibody - C-terminal region (ARP75584_P050)
Reacts with
Human
Application
WB
$289.00
  pAb ARP51650_P050 MLX Antibody - N-terminal region (ARP51650_P050)
Reacts with
Human
Application
WB
$289.00
  pAb ARP72516_P050 MAF Antibody - C-terminal region (ARP72516_P050)
Reacts with
Human
Application
WB
$289.00
  pAb ARP75292_P050 MAML1 Antibody - middle region (ARP75292_P050)
Reacts with
Human
Application
WB
$289.00
  pAb ARP74056_P050 MECP2 Antibody - N-terminal region (ARP74056_P050)
Reacts with
Human
Application
WB
$289.00
  pAb ARP58372_P050 MFSD3 Antibody - N-terminal region (ARP58372_P050)
Reacts with
Human
Application
WB
$289.00
  pAb ARP32704_P050 MNT Antibody - C-terminal region (ARP32704_P050)
Reacts with
Human
Application
WB
$289.00
  pAb ARP50514_P050 MDFI Antibody - middle region (ARP50514_P050)
Reacts with
Human
Application
WB
$289.00
  pAb ARP56437_P050 MK11 Antibody - N-terminal region (ARP56437_P050)
Reacts with
Human
Application
WB
$289.00
  pAb ARP33721_T100 MORF4L2 antibody - N-terminal region (ARP33721_T100)
Reacts with
Mouse, Human, Dog, Pig, Horse, Rabbit, Rat, Bovine, Guinea pig
Application
IHC, WB
$229.00
  pAb ARP33720_T100 MORF4L2 antibody - N-terminal region (ARP33720_T100)
Reacts with
Human, Mouse, Dog, Pig, Horse, Rabbit, Rat, Yeast, Bovine, Guinea pig
Application
IHC, WB
$229.00
  pAb ARP68610_P050 MACROD1 Antibody - N-terminal region (ARP68610_P050)
Reacts with
Pig, Horse, Rat, Guinea pig, Bovine, Mouse, Human, Dog
Application
WB
$289.00
  pAb ARP32018_P050 MEOX1 Antibody - C-terminal region (ARP32018_P050)
Reacts with
Pig, Bovine, Human, Dog, Horse, Rabbit, Guinea pig, Rat, Mouse
Application
WB
$289.00
  pAb ARP50710_P050 Maf1 antibody - N-terminal region (ARP50710_P050)
Reacts with
Bovine, Mouse, Human, Pig, Horse, Rat, Guinea pig
Application
WB
$289.00
  pAb ARP32777_T100 MXD4 antibody - N-terminal region (ARP32777_T100)
Reacts with
Human, Dog, Pig, Rabbit, Guinea pig, Sheep, Bovine, Mouse
Application
WB
$229.00
  pAb ARP37098_P050 Msx3 Antibody - N-terminal region (ARP37098_P050)
Reacts with
Mouse, Rat
Application
WB
$289.00
  pAb ARP43219_P050 March2 antibody - middle region (ARP43219_P050)
Reacts with
Dog, Pig, Horse, Rabbit, Mouse, Rat, Guinea pig, Human, Bovine
Application
WB
$289.00
  pAb ARP38628_P050 MED6 Antibody - C-terminal region (ARP38628_P050)
Reacts with
Human, Horse, Rabbit, Dog, Rat, Bovine, Mouse
Application
IHC, WB
$289.00
  pAb ARP35727_P050 MED21 antibody - C-terminal region (ARP35727_P050)
Reacts with
Pig, Horse, Rat, Dog, Human, Bovine, Guinea pig, Mouse
Application
WB
$289.00
  pAb ARP50617_P050 MBTD1 Antibody - N-terminal region (ARP50617_P050)
Reacts with
Mouse, Dog, Bovine, Pig, Horse, Rabbit, Rat, Guinea pig, Human, Zebrafish, Yeast
Application
WB
$289.00
  pAb ARP64117_P050 MYOT antibody - C-terminal region (ARP64117_P050)
Reacts with
Mouse, Human, Rat, Dog, Bovine, Pig, Horse, Rabbit, Guinea pig
Application
WB
$289.00
  pAb ARP64512_P050 MAEA antibody - N-terminal region (ARP64512_P050)
Reacts with
Human, Dog, Bovine, Horse, Rabbit, Rat, Guinea pig, Mouse, Zebrafish
Application
WB
$289.00
  pAb ARP32010_P050 Mafg Antibody - N-terminal region (ARP32010_P050)
Reacts with
Bovine, Dog, Zebrafish, Horse, Rat, Guinea pig, Human, Mouse
Application
WB
$289.00
  pAb ARP31212_P050 MITF Antibody - middle region (ARP31212_P050)
Reacts with
Human, Pig, Bovine, Horse, Rabbit, Rat, Guinea pig, Dog, Sheep, Mouse
Application
WB
$289.00

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Showing 1 - 30 of 229